Ailuropoda melanoleuca (giant panda): 100479481
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Entry
100479481 CDS
T01329
Gene name
MDM2
Definition
(RefSeq) E3 ubiquitin-protein ligase Mdm2 isoform X1
KO
K06643
E3 ubiquitin-protein ligase Mdm2 [EC:
2.3.2.27
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml01522
Endocrine resistance
aml01524
Platinum drug resistance
aml04068
FoxO signaling pathway
aml04110
Cell cycle
aml04115
p53 signaling pathway
aml04120
Ubiquitin mediated proteolysis
aml04144
Endocytosis
aml04151
PI3K-Akt signaling pathway
aml04218
Cellular senescence
aml04625
C-type lectin receptor signaling pathway
aml04919
Thyroid hormone signaling pathway
aml05163
Human cytomegalovirus infection
aml05165
Human papillomavirus infection
aml05169
Epstein-Barr virus infection
aml05200
Pathways in cancer
aml05202
Transcriptional misregulation in cancer
aml05203
Viral carcinogenesis
aml05205
Proteoglycans in cancer
aml05206
MicroRNAs in cancer
aml05214
Glioma
aml05215
Prostate cancer
aml05218
Melanoma
aml05219
Bladder cancer
aml05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100479481 (MDM2)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100479481 (MDM2)
04151 PI3K-Akt signaling pathway
100479481 (MDM2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100479481 (MDM2)
09143 Cell growth and death
04110 Cell cycle
100479481 (MDM2)
04115 p53 signaling pathway
100479481 (MDM2)
04218 Cellular senescence
100479481 (MDM2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
100479481 (MDM2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100479481 (MDM2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100479481 (MDM2)
05202 Transcriptional misregulation in cancer
100479481 (MDM2)
05206 MicroRNAs in cancer
100479481 (MDM2)
05205 Proteoglycans in cancer
100479481 (MDM2)
05203 Viral carcinogenesis
100479481 (MDM2)
09162 Cancer: specific types
05214 Glioma
100479481 (MDM2)
05220 Chronic myeloid leukemia
100479481 (MDM2)
05218 Melanoma
100479481 (MDM2)
05219 Bladder cancer
100479481 (MDM2)
05215 Prostate cancer
100479481 (MDM2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100479481 (MDM2)
05169 Epstein-Barr virus infection
100479481 (MDM2)
05165 Human papillomavirus infection
100479481 (MDM2)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100479481 (MDM2)
01522 Endocrine resistance
100479481 (MDM2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
aml04131
]
100479481 (MDM2)
04121 Ubiquitin system [BR:
aml04121
]
100479481 (MDM2)
Enzymes [BR:
aml01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
100479481 (MDM2)
Membrane trafficking [BR:
aml04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100479481 (MDM2)
Ubiquitin system [BR:
aml04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
MDM2/MDM4 proteins
100479481 (MDM2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
zf-C3HC4_3
SWIB
zf-RanBP
Motif
Other DBs
NCBI-GeneID:
100479481
NCBI-ProteinID:
XP_002918363
Ensembl:
ENSAMEG00000008526
LinkDB
All DBs
Position
15
AA seq
487 aa
AA seq
DB search
MCNTNMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQHEPSDSGT
SVSENRCHLEGGSDQKEPVQELQEEKPSSSDLVSRPSTSSRRRAISETEEHSDELPGERQ
RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDS
VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLA
DYWKCTSCNEMNPPLPPHCNRCWALRENWLPEDKGKIPEKAKLENSTQVEEGFDVPDCKK
TAVNDSRESCAEENDDKITQASQSQESEDYSQPSTSNSIIYSSQEDVKELEREETQDKEE
IVESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQM
IVLTYFP
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atgtgcaataccaacatgtctgtgtctactgatggtgctgtaagcacctcacagattcca
gcttcggaacaggagaccctggttagaccaaagcctttgcttttgaagttgttaaagtct
gttggtgcacaaaaagacacttatactatgaaagaggttatattttatcttggccagtat
attatgactaaacgattatatgatgagaagcaacagcatattgtgtattgttccaatgat
cttctaggggatttgtttggagtgccaagcttctctgtgaaagagcacaggaaaatatat
acaatgatctacagaaacttggtagtagtcaatcagcatgaaccttcagattcaggcaca
tctgtgagtgaaaataggtgtcaccttgaaggtgggagtgatcaaaaggagccggtgcaa
gagttgcaggaagagaaaccttcatcttcagatttggtttctagaccatctacctcatct
agaaggagagcaattagtgagacagaagaacattcagatgaattacctggtgaacggcag
agaaagcgccacaaatctgatagtatttccctttcctttgatgaaagccttgctctgtgt
gtaataagggagatatgctgtgaaagaagcagtagcagtgaatcaacagggacaccatca
aatccggatcttgatgctggtgtaagtgaacattcaggtgactggttggatcaggattca
gtttcagatcaattcagtgtagaatttgaagttgagtctctcgattcagaagattacagt
cttagtgaagaaggacaagaactctcagatgaagacgatgaggtatatcgagtaactgtg
tatcaggcaggggagagtgataccgattcatttgaagaagatcctgaaatttccttagct
gactactggaagtgtacttcgtgcaatgaaatgaatcctcctcttccgcctcattgcaac
agatgttgggcccttcgtgagaactggcttcctgaagataaagggaaaatacctgagaaa
gccaaactagaaaactcaacacaagtagaagagggctttgatgtccctgattgtaaaaaa
actgcagtgaatgattccagagaatcatgtgctgaggaaaatgatgataaaatcacacaa
gcctcccaatcccaagaaagtgaggattattctcagccatcaacttctaacagcatcatt
tatagcagccaagaagatgtcaaagagcttgagagggaagaaacacaagacaaagaagaa
attgtggaatctagttttccccttaatgccattgaaccttgtgtgatttgccaaggtcga
cctaaaaacggttgcattgttcatggcaaaacaggacatcttatggcatgctttacatgt
gcaaagaagctcaagaaaaggaataagccctgtccagtatgtagacaaccaattcaaatg
attgtgctaacttatttcccctag
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