Ailuropoda melanoleuca (giant panda): 100480891
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Entry
100480891 CDS
T01329
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X5
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml01524
Platinum drug resistance
aml03440
Homologous recombination
aml03460
Fanconi anemia pathway
aml04120
Ubiquitin mediated proteolysis
aml04151
PI3K-Akt signaling pathway
aml05206
MicroRNAs in cancer
aml05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100480891 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
100480891 (BRCA1)
03460 Fanconi anemia pathway
100480891 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
100480891 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100480891 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
100480891 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100480891 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
aml01009
]
100480891 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
aml04121
]
100480891 (BRCA1)
03036 Chromosome and associated proteins [BR:
aml03036
]
100480891 (BRCA1)
03400 DNA repair and recombination proteins [BR:
aml03400
]
100480891 (BRCA1)
Enzymes [BR:
aml01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
100480891 (BRCA1)
Protein phosphatases and associated proteins [BR:
aml01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100480891 (BRCA1)
Ubiquitin system [BR:
aml04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
100480891 (BRCA1)
Multi subunit type E3
BRCC complex
100480891 (BRCA1)
Chromosome and associated proteins [BR:
aml03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
100480891 (BRCA1)
DNA repair and recombination proteins [BR:
aml03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
100480891 (BRCA1)
BRCA1-A complex
100480891 (BRCA1)
BRCA1-B complex
100480891 (BRCA1)
BRCA1-C complex
100480891 (BRCA1)
BRCA complex
100480891 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
100480891 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4_4
zf-RING_UBOX
zf-C3HC4_2
zf-C3HC4
BRCT_2
zf-Nse
zf-RING_6
zf-RING_5
zf-RING_2
RING_XB3-XBAT31
zf-C3HC4_3
Motif
Other DBs
NCBI-GeneID:
100480891
NCBI-ProteinID:
XP_019648408
Ensembl:
ENSAMEG00000000171
LinkDB
All DBs
Position
13:complement(26633442..26695879)
Genome browser
AA seq
1843 aa
AA seq
DB search
MDLPADRVEEVQDVLNAMQKILECPICLELIKEPVSTKCDHIFCKSLQESTRFSQLVEEL
LKIIHAFELDTGLQFVNSYNFSKENNSPDHLKEEVSIIQSMGYRNRAKRLRQSEPENPTL
QETSLSVHLSDLGIVRSLRTKQQIQPQNKSVYIELGSDSSEDTVNKASYCSVGDDELLQI
TPQGARAEASLNPAKKAACEISEDITNIEYHQSGNKDLTTTEKHATEKHPEKYQGISVSN
LHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEVCNKSKQLGLARSQQSRWAESKETC
NDRQTPSTEKKVLLNADPLHGRKKPRKQKPACSDCPRDSQDVPWITLNSSIQKVNEWFFR
SDEMLTSDDSHDGGSESNTEVAGAVEVPNEVDGYSGSSEKVDLMASDPQDALIRGSERVH
PKSVESNIEDKIFGKTYRRKASLPSHTNEDLIIGVRAIEPQTTRAHPLTNKAKCKRRTTS
GLLPEDFIKKVDLAVVPKTPEKLVEGTNQIARNGHLMNITNNGPENEAKGDYVQNEKNAN
PTESLEKESAFRSKAEPISSSISNMELELNSCCSKASKKNRLRRKSSTRHACALEFVVNR
NPSPPDHSELQIDSCSSSEEMKKQHLDRMPVRHSKTLQLMEGKEPATGARRGSKPGEQIN
KRLASHAFPELNLTSVPGFSANCSSSNKPQEFVNPGLQREEIEESLGRIRVSDSTRDPKE
LLLGGGRGLQTERSVESIHISLVPDTDYGTQDSISLLEADTLRKAKTAPNRRANLCAATE
NPKEPIHGCSKDTRNDTEGFADPLTCEDNHTQETRIAMEESELDTQYLYNTFKVSKRQSF
ALFSNPGDPEKDCAMVCAHSGALRKQSPKVTLEGGQKEENQGKKESEIKHVQAVHATAGF
SAVSQQAKKPGDYAKCSIKGGAKLCPSSPFRGKETELLIANNRGISHNPYHIPPLSPIRS
YVKTLCKKNPSEERFEQHSMSPERAMGNESVIQSTVSTISQNNIRESTLKEVSSSSVNEV
GSSTNEAGSSINEVGSSGENVQAELGRHRGPKVNAMLRLGLMQPEVYKQSPPVSNCKHPE
MKRQGENEGVVLSVNADFSPCLISDNPEQPMGSTHASQVCSETPDDLLNGDKIKGKSSFA
ESDIRERSAVFSKSVQKGAFGRSHLDETHLAQGHQRGARKLESSEENTSSEEEELPCFQH
LLFGKVTNTPSQPTSHNAVATEGLSKKTEENLDSRKNSLSDLSNQGPSAKASQEHYLSEE
ARCSGSLFSSQHSALEDLIVTTNSQDPFLMFDSPSKQVRHQSENLDVLSDKELVSDDDDE
RELGLDEDNHEEQSVDSDLGEAASGYESETSLSEDCSGLSSQSDILTTQQRDTMQDNLIK
LQQEMAELEAVLEQHGSQPSRSSPSLLAGSGAPEDLLNPEQNTSGKAVLTSEKSSDYPIS
QNPESLSADKFQVSLDSSTSKNKEPGTRRSSPSPSRLLDTRWYVHSGPRNLQNRNCPSQK
ELIKVVSVEEQAPTKSEAQEVVEQSLPRPDLEGTPYLESGISLFSDDPESDPSADRAPEP
AHVSSMPTSTSALKLPQFQVEESAKSTAAVHVANTAGYNKREDTVGREKPEVISSVKKIN
GAISMVASGLTPKEFMLVQKFAKKHHIALTNQISEETTHVIMKTDAEFVCERTLKYFLGI
AGGKWVVSYFWVTQSIKERKILDEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEVC
CYGPFTNMPTDQLEWMVHLCGASVVKEPSSFTLSKGTHAVVVVQPDAWADNSGFHAIGQM
CEAFVVTREWVLDSVALYQCQELDTYLIPQIPRAAAPASQPCA
NT seq
5532 nt
NT seq
+upstream
nt +downstream
nt
atggatttacctgcggatcgtgttgaagaagtacaagatgtcctcaatgctatgcagaaa
atcttggagtgtccaatctgtctggagttgatcaaagagcctgtttccacgaagtgtgat
cacatattttgcaaaagcctacaagaaagtacaagatttagtcaacttgttgaagagctg
ttgaaaatcattcatgcttttgagctggacacaggattgcagtttgtaaacagctataat
ttttcaaaagaaaataactctcccgaccatctaaaggaggaagtttctattatccaaagt
atgggctatcgaaaccgtgccaaaagacttcgacagagtgaacctgaaaaccctaccttg
caggaaaccagtcttagtgtccacctctctgaccttggaattgtgagatctctgaggaca
aagcagcagatacagcctcagaataagtctgtctacattgaattgggatctgattcttct
gaagatacagttaataaggcaagttattgcagtgtgggagacgacgagttgttacaaatc
acccctcaaggagccagggctgaagccagtttgaatcctgcaaaaaaggctgcttgtgaa
atttctgaggacataacaaatattgaatatcatcaatctggtaataaagatttgaccacc
actgagaagcatgcaactgagaagcatccagaaaagtatcagggtatttctgtttcaaac
ttgcatgtggagccatgtggcacaaatactcatgccagctcattacagcatgagaacagc
agtttattactcactaaagacagaatgaatgtagaaaaggctgaagtctgtaataaaagc
aaacagcttggcttagcaaggagccaacagagcagatgggctgaaagtaaggaaacatgt
aatgataggcagactcccagcacagagaaaaaggtacttctgaatgctgatcccctgcat
gggagaaaaaaaccgaggaagcagaaacctgcatgctctgactgtcctagagattctcaa
gatgttccttggataacactgaatagtagcatacagaaagttaatgagtggtttttcaga
agtgatgaaatgttaacttctgatgactcacatgacgggggatctgaatcgaatactgaa
gtagctggtgcagtagaagttccaaatgaagtggacggatattctggttcttctgagaaa
gtagatttaatggccagtgatcctcaggatgctttgatacgtggaagtgaaagagtccac
cccaagtcagtagagagtaatatcgaagataaaatatttgggaaaacctaccggaggaag
gcgagcctccctagccacacgaatgaagatctaattataggagtgcgtgctattgagcct
cagacaacgcgagcccatcccctcacaaataaagcaaagtgtaaaaggagaactacgtca
ggccttcttcctgaggattttatcaagaaagtagatttggccgttgttccaaagactcct
gaaaagctagttgagggaaccaaccaaatcgcgcgaaatggtcacttgatgaatattaca
aataacggtcctgagaatgaagcaaaaggtgattatgttcagaatgagaaaaatgctaac
ccaacagaatcattggaaaaagaatctgcttttagaagcaaagctgaaccgataagcagc
agtataagcaatatggaactggaattaaatagctgctgttcgaaagcctctaagaagaac
agactgaggaggaagtcctccaccaggcacgcttgtgcgcttgaattcgtagtcaataga
aatccaagcccgcctgatcatagcgaactacagatcgatagttgttctagcagtgaagag
atgaagaaacagcatttggaccgaatgccagtcagacacagcaaaacgcttcagctcatg
gaaggtaaagaacctgcaactggagccaggaggggcagtaagccaggtgaacagataaat
aagagacttgccagtcatgctttcccagagctaaatttgacaagtgtacctggtttttcc
gctaactgttcaagttctaataaacctcaagagtttgtcaaccctggccttcaaagagaa
gaaatagaagagagcctaggaagaattcgagtgtctgatagcaccagagatcccaaagag
ctgctcttgggtggaggaagaggtttgcaaactgaaagatctgtggagagtatccatatt
tcactggtacctgatactgattacggcactcaggacagtatctcgttactggaagctgac
accctaaggaaggcaaaaacagcaccaaatcgacgtgcgaatctgtgcgcagcaactgaa
aaccccaaggaacctatccacggttgttctaaagatactagaaatgacacagagggtttt
gcagatccactgacatgtgaagataaccacactcaggagacaagaatagcaatggaagag
agtgaacttgacacacagtatttatacaacacgttcaaggtttcaaagcgtcagtcattt
gctctgttttcaaatccaggagatccagaaaaggactgtgcaatggtctgtgcccactcc
ggggccttaaggaaacaaagtccaaaagtcactcttgaaggtggacaaaaagaagaaaat
cagggaaagaaagagtctgaaatcaagcatgtgcaggcagttcatgcaactgcaggcttt
tctgcagtgagtcagcaagctaagaagccaggtgattatgccaaatgtagcataaaagga
ggcgctaagctttgtccgtcatctccgttcagaggcaaggaaacggaactccttattgca
aataaccgtggaatttcccacaacccttatcatataccaccactttctcccatcagatca
tatgttaaaactctatgtaagaaaaacccgtcagaggaaaggtttgagcagcattcaatg
tcacccgaaagagcaatgggaaatgagagcgtcattcaaagtacagtgagcacaattagc
caaaataacattagagaaagcactttgaaggaagtcagctcaagcagtgttaatgaagta
ggttccagtactaatgaagcaggctctagcattaatgaagtgggttccagtggtgaaaac
gttcaggcagaactaggtagacaccgaggacctaaagtaaacgctatgctcagattaggt
cttatgcaacctgaagtctataagcaaagccctcctgtaagtaattgtaaacatccggaa
atgaaaaggcaaggagaaaacgaaggcgtagttctgtctgttaatgcagatttctctcca
tgtctaatttcagataaccccgaacaaccgatgggaagcactcacgcttctcaggtttgt
tcggagacacctgatgacctattaaatggtgacaaaataaagggaaaaagcagctttgcc
gaaagtgacattagggaaagatctgctgtttttagcaaaagtgtccagaaaggagccttc
ggaaggagccatttagacgaaacacatttggcccagggtcaccaaagaggggccaggaaa
ttagagtcctcagaagagaacacatccagtgaagaggaagagcttccgtgcttccaacac
ttactatttggtaaagtaaccaacacaccttctcagcctaccagtcacaatgctgttgcc
acagagggtctgtctaagaaaacagaggagaacctagactcacggaagaatagtttaagt
gacctcagtaaccagggaccatcagcaaaggcatcccaggaacattatcttagtgaggag
gcaaggtgttctgggagcttattttcttcacagcacagtgcattggaagacttgatagtt
actacaaatagccaggatcctttcttgatgttcgattccccttccaaacaagtgaggcat
cagtctgaaaacctggatgttctgagcgacaaggaattggtttcagatgatgatgatgaa
agggaacttggcctggacgaagataatcacgaagaacagagtgtggattcagacttaggt
gaagcggcatccgggtatgagagtgaaacgagcctctccgaagactgttcagggttgtcc
tctcagagtgatattttaaccactcagcagagggataccatgcaagataacctgataaag
ctccagcaggaaatggccgaactggaagccgtgttagagcagcacgggagccagccttct
cgcagctccccttccctcctagcaggttctggtgccccagaggatctgctaaatccggaa
caaaacacatcaggaaaagcagtattaacttcagagaaaagtagtgactatcctataagc
cagaatcccgaaagcctttctgctgacaaatttcaagtatctctggatagttccaccagt
aaaaataaagaaccaggaacaagaaggtcttccccttctccatcccggttgttagatacc
aggtggtatgtgcacagcggcccaaggaatcttcagaacagaaactgcccgtctcaaaag
gagctcattaaggtcgtcagtgtggaggaacaagcaccgactaagtcagaggcgcaagag
gtcgtggagcagtctttgccaagaccagatctggagggaaccccttacctcgagtctgga
atcagcctcttctctgatgaccctgagtctgatccctctgcagacagagccccagagcca
gctcatgttagcagcatgccaacttcaacctctgctttgaaattaccccaatttcaagtt
gaagaatcagccaagagtacagctgctgtccatgttgctaatactgctgggtataataag
agggaagacactgtgggcagggagaagccagaagttatatcttcagtaaaaaaaatcaac
ggagcaatatctatggtggcatcaggcttaaccccaaaagaatttatgcttgtgcagaag
tttgccaaaaaacaccacattgctttaacgaatcaaatttctgaagagactactcacgtc
atcatgaaaacagatgctgagtttgtgtgcgaacggacgctgaaatattttctgggtatc
gcaggaggaaaatgggtagttagctatttctgggtgacccagtctattaaagaaagaaag
atactagatgagcatgattttgaagtcagaggagatgttgtgaatggaagaaaccaccaa
ggtccgaagcgagcaagagaatcccaggacagaaagatcttcaggggcctagaagtctgt
tgctatgggccctttaccaacatgcccacagatcagctagagtggatggtgcacctctgt
ggggcttctgtggtgaaggagccttcgtcattcactcttagcaagggtactcacgcagtg
gtggtcgtgcagccggatgcctgggcagacaacagtggcttccatgcgattgggcagatg
tgtgaggcatttgtggtgacccgagagtgggtgttggacagtgtagccctctaccagtgc
caggagctggacacctacctgatcccgcagattcccagagctgctgctcccgccagccag
ccatgtgcatag
DBGET
integrated database retrieval system
