Actinomyces oris: AXE84_08290
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Entry
AXE84_08290 CDS
T04280
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
aos
Actinomyces oris
Pathway
aos00020
Citrate cycle (TCA cycle)
aos00630
Glyoxylate and dicarboxylate metabolism
aos00785
Lipoic acid metabolism
aos01100
Metabolic pathways
aos01110
Biosynthesis of secondary metabolites
aos01120
Microbial metabolism in diverse environments
aos01200
Carbon metabolism
aos01210
2-Oxocarboxylic acid metabolism
Module
aos_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
aos00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AXE84_08290 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
AXE84_08290 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AXE84_08290 (kgd)
Enzymes [BR:
aos01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AXE84_08290 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AXE84_08290 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AXE84_08290 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AXE84_08290 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AMD99410
UniProt:
A0A109WAD7
LinkDB
All DBs
Position
complement(2051432..2055259)
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AA seq
1275 aa
AA seq
DB search
MPTQDQISPGFGANEWMVEEMRAAWSADPSSVSPQWRELFETDPGAGLHQPGPASSNGSA
SSAAGGPRRATITPQAASSLRRSSAVQDVTRSDLPPAPPSDTAPPTSPYAQRQAGHPAHD
QDGDAYEDRTTRLKGAAARTAKNMDDSLSMPTATSARAVPAKVLIENRSVINTHLARTRG
GKVSFTHLIGWAVVESLTEMPSMNVSYGVDEAGKPVLHEPAHVAFGLAIDVPGSDGQRRL
LVPSIKQADLMDLSQFVKAYEALVAKARENKLDLDDFRGTTVTLTNPGMIGTLHSVPRLM
PGQGLIVGVGAMDYPAAFAGASPDTLARQAIGKVVTLTSTYDHRVIQGAASGEFLRLVER
KLLGLDGFWNRAFESLRIPLEPVKWVRDTTYDPELETGKPARVAELIHAYRQRGHLAADN
DPLTYRLRRHPDLDITSYGLSLWDLDRSFPTRGLGGRDRATLREILRMLRDAYCRTVGVE
YMHIQDPAQRAWWQERLERDWEDIADEERRRILTKLEQAEAFETFLQTKYVGQKRFSLEG
GESLIVALDRLLDAAAHDGLDEVVIGMAHRGRLNVLTNIAGKSYGQVFDEFEGNGVIEGA
GTGDVKYHLGTVGVFSGTDGVSTRVSLAANPSHLETVDGVVEGIVRAKQDRIGLGEKGYT
VMPVLVHGDAAFAGQGVVYETLNMSQLPAYRTGGTVHVVVNNQIGFTTGSASARSTIYAT
DLAKGLQVPIFHVNADDPETVARTARHAYEYRRTFHKDVIIDLICYRRRGHNEGDDPSMT
QPLMYRLIDSLDSTRGVYTSALVGRGDITPQEAQEIAKSYQDELERVFTEARIQVTGGTG
SDDAGDATDTSTQDLSDPTKVGVPLSSLEIPYSQRAGTGMMLGWTSAVPRDVVERIGDAQ
VAWPESFTVHPKLQAMLSKRREATREGGIDWGLGELIALGSLLMEGVPIRLAGEDARRAT
FAQRHAVLHDHTSGQEWTPLSFLTPDQAPLEIYDSLLSEYAALAFEYGYSVERPEGLTMW
EAQFGDFANGAQSVIDEYVTSAAQKWGQRSGLVMLLPHGQEGQGPDHSSARIERYLQMCA
QDNMLVAQPSTPASYFHLLREHTYHRPRRPLIVFTPKQLLRLKAACSPVEAFTSGTFQPV
IGETDDAVLTSAQKQGVDRVLLCSGRVYYDLLAHRTKTGDTRTAIVRLEQLYPLESSAIA
EALAPFSGAELVWVQDEPANQGMWPYLALNLPTDLTGGVLPTLVSRPEAAAPAVGTAGLH
RAQQEEILRQAFTRH
NT seq
3828 nt
NT seq
+upstream
nt +downstream
nt
gtgcccacgcaggaccagatcagcccaggcttcggtgccaacgagtggatggtggaggag
atgcgggccgcctggtcggcggatccgtcctccgtgagtccgcagtggcgcgagctcttc
gagaccgatccgggtgccggcctgcaccaaccgggccctgcctcctccaacggctcggcg
tcgtcggccgccggtgggccgcgccgggccaccatcacgccccaggccgcctcctccctg
cgccgctcctccgccgtccaggacgtcacgcgctccgacctgccgccggccccgccgtcg
gacaccgcgcccccgacctccccctacgcccagcgccaggccggccaccccgctcatgac
caggacggtgacgcctacgaggaccgcactaccaggctcaagggtgcggcggcccgcacc
gccaagaacatggacgattccctgtccatgcccacggccacctccgcccgggccgtgccc
gccaaggtcctcattgagaaccgctccgttatcaacacccacctggcccgcacccgcggc
ggcaaggtctccttcacccacctcatcggctgggcggtggtcgagtccctgaccgagatg
ccctcgatgaacgtctcctacggggtcgacgaggcgggcaagccggtcctgcacgagccg
gcccacgtggccttcggcctggccatcgacgtgcccggctccgacgggcagcgccgcctg
ctggtgccctccatcaagcaggccgacctcatggacctgtcccagttcgtgaaggcctac
gaggccctcgtggccaaggcccgcgagaacaagctggaccttgacgacttccggggtacc
accgtgaccctgaccaaccccggcatgatcggcaccctgcactcggtgccgcgcctcatg
cccggccaggggctcatcgtgggggtcggcgccatggactacccggccgccttcgccggt
gccagccccgacaccctggcccgccaggccatcggcaaggtcgtcaccctgacctccacc
tacgaccaccgagtcatccagggcgccgcctccggtgagttcctgcgcctggtggagcgc
aagctgctgggactggacggtttctggaaccgggccttcgagtccctgcgcattcccctc
gagccggtcaagtgggtgcgtgacaccacttacgaccccgagctggagaccggcaagccg
gcgcgcgtggccgagctcatccacgcctaccgccagcgcggccacctggcggccgacaac
gacccgctcacctaccgcctgcgccgtcaccccgacctggacatcacctcctacgggctg
agcctgtgggacctggaccgctccttccccacccggggcctgggcgggcgcgaccgggcc
accctgcgcgagatcctcaggatgctgcgcgacgcctactgccgcaccgtgggcgtggag
tacatgcacatccaggaccccgcgcagcgcgcctggtggcaggagcggctcgagcgcgac
tgggaggacatcgccgacgaggagcgccgtcggatcctcaccaagctggagcaggccgag
gccttcgagaccttcctgcagaccaagtacgtgggccagaagcgcttcagcctcgagggc
ggggagtccctcatcgtggccctggaccgcctgctcgacgccgccgcccacgacggcctc
gacgaggtcgtcatcggcatggcccaccgcggccgcctcaacgtgctcaccaacatcgcc
ggcaagtcctacggccaggtcttcgacgagttcgagggcaacggcgtcatcgagggcgcc
ggcaccggggacgtcaagtaccacctgggcaccgtgggcgtcttctccgggaccgacggc
gtctccacccgcgtctccctggccgccaacccctcccacctggagacggtcgacggcgtc
gtcgagggcatcgtgcgcgccaagcaggaccgcatcggcctgggcgagaagggctacacg
gtcatgccggtcctcgtccacggtgacgccgccttcgccggccagggcgtggtctacgag
accctcaacatgagccagctgcccgcctaccgcaccggcggcaccgtccacgtcgtcgtc
aacaaccagatcggattcaccaccggctcggcttcggcccgctccaccatctacgccacc
gacctggccaagggcctgcaggtgccgatcttccacgtcaacgccgacgaccccgagacg
gtggcccgcaccgcccgccacgcctacgagtaccgacgcaccttccacaaggacgtcatc
atcgacctcatctgctatcggcgccgcggccacaacgagggcgacgacccctcgatgacc
cagccgctcatgtaccggctcatcgactcgctggactccacccgcggcgtctatacctcc
gccctcgtggggcgcggcgacatcaccccgcaggaggcccaggagatcgccaagagctac
caggacgagctggagcgggtcttcaccgaggcccgcatccaggtcaccgggggcacgggc
tccgacgacgccggggacgccaccgacacctccacacaggacctgtcggacccgacgaag
gtgggcgtgcccctgtcctccctggagatcccctactcccagcgggcgggtaccggcatg
atgctcggctggacctcggccgtgccgcgcgacgtcgtcgagcgcatcggcgacgcccag
gtcgcctggcccgagtccttcaccgtccaccccaagctccaggccatgctctccaagcgc
cgcgaggccacccgcgagggcggcatcgactgggggctcggggagctcatcgccctgggg
agcctgctcatggagggcgtgccgatccgactggccggcgaggacgcccgccgcgccacc
ttcgcccagcgccacgccgtcctgcacgaccacacctccgggcaggagtggacgcccctg
agcttcctgaccccggaccaggcgcccctggagatctacgactccctgctcagcgagtac
gccgccctggccttcgagtacggctactccgtggagcgccccgagggactgaccatgtgg
gaggcccagttcggcgacttcgccaacggcgcccagtccgtcatcgatgagtacgtcacc
tccgccgcccagaagtgggggcagcgctccggcctggtcatgctgctcccccacggccag
gaggggcagggacccgaccactcctcggcccgcatcgagcgctacctgcagatgtgcgcc
caggacaacatgctggtggcccagccctccacgcccgccagctacttccacctcctgcgg
gagcacacctaccaccgcccgcgccgcccgctgatcgtcttcacccccaagcagctgctg
cgtctgaaggccgcttgctccccggtggaggccttcacctccggcaccttccagccggtc
atcggggagaccgacgacgccgtcctgacctcggcgcagaaacagggcgtggaccgggtg
ctgctgtgctcgggtcgcgtctactacgacctgctggcccaccggaccaagaccggggac
acgagaacggccatcgtccgcctcgagcagctctacccgctggagagctcggccatcgcc
gaggcactagcccccttcagcggggccgagctcgtgtgggtccaggacgagcccgccaac
cagggcatgtggccctacctggcgctcaacctgccaaccgacctgaccggcggcgtcctg
cccacgctggtctcccggcccgaggccgccgccccggccgtgggcaccgccggtctccac
cgcgcccagcaggaggagatcctccgccaggccttcacccgccactga
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