KEGG   Balaenoptera acutorostrata scammoni (minke whale): 103010512
Entry
103010512         CDS       T03086                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
bacu  Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu01521  EGFR tyrosine kinase inhibitor resistance
bacu01522  Endocrine resistance
bacu04010  MAPK signaling pathway
bacu04012  ErbB signaling pathway
bacu04014  Ras signaling pathway
bacu04062  Chemokine signaling pathway
bacu04068  FoxO signaling pathway
bacu04072  Phospholipase D signaling pathway
bacu04150  mTOR signaling pathway
bacu04151  PI3K-Akt signaling pathway
bacu04380  Osteoclast differentiation
bacu04510  Focal adhesion
bacu04540  Gap junction
bacu04550  Signaling pathways regulating pluripotency of stem cells
bacu04630  JAK-STAT signaling pathway
bacu04650  Natural killer cell mediated cytotoxicity
bacu04660  T cell receptor signaling pathway
bacu04662  B cell receptor signaling pathway
bacu04664  Fc epsilon RI signaling pathway
bacu04714  Thermogenesis
bacu04722  Neurotrophin signaling pathway
bacu04910  Insulin signaling pathway
bacu04912  GnRH signaling pathway
bacu04915  Estrogen signaling pathway
bacu04917  Prolactin signaling pathway
bacu04926  Relaxin signaling pathway
bacu04935  Growth hormone synthesis, secretion and action
bacu05034  Alcoholism
bacu05160  Hepatitis C
bacu05161  Hepatitis B
bacu05163  Human cytomegalovirus infection
bacu05165  Human papillomavirus infection
bacu05200  Pathways in cancer
bacu05203  Viral carcinogenesis
bacu05205  Proteoglycans in cancer
bacu05206  MicroRNAs in cancer
bacu05210  Colorectal cancer
bacu05211  Renal cell carcinoma
bacu05213  Endometrial cancer
bacu05214  Glioma
bacu05215  Prostate cancer
bacu05220  Chronic myeloid leukemia
bacu05221  Acute myeloid leukemia
bacu05223  Non-small cell lung cancer
bacu05224  Breast cancer
bacu05225  Hepatocellular carcinoma
bacu05226  Gastric cancer
bacu05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:bacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103010512 (GRB2)
   04012 ErbB signaling pathway
    103010512 (GRB2)
   04014 Ras signaling pathway
    103010512 (GRB2)
   04630 JAK-STAT signaling pathway
    103010512 (GRB2)
   04068 FoxO signaling pathway
    103010512 (GRB2)
   04072 Phospholipase D signaling pathway
    103010512 (GRB2)
   04151 PI3K-Akt signaling pathway
    103010512 (GRB2)
   04150 mTOR signaling pathway
    103010512 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103010512 (GRB2)
   04540 Gap junction
    103010512 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    103010512 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    103010512 (GRB2)
   04660 T cell receptor signaling pathway
    103010512 (GRB2)
   04662 B cell receptor signaling pathway
    103010512 (GRB2)
   04664 Fc epsilon RI signaling pathway
    103010512 (GRB2)
   04062 Chemokine signaling pathway
    103010512 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103010512 (GRB2)
   04912 GnRH signaling pathway
    103010512 (GRB2)
   04915 Estrogen signaling pathway
    103010512 (GRB2)
   04917 Prolactin signaling pathway
    103010512 (GRB2)
   04926 Relaxin signaling pathway
    103010512 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    103010512 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    103010512 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103010512 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    103010512 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103010512 (GRB2)
   05206 MicroRNAs in cancer
    103010512 (GRB2)
   05205 Proteoglycans in cancer
    103010512 (GRB2)
   05203 Viral carcinogenesis
    103010512 (GRB2)
   05231 Choline metabolism in cancer
    103010512 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103010512 (GRB2)
   05225 Hepatocellular carcinoma
    103010512 (GRB2)
   05226 Gastric cancer
    103010512 (GRB2)
   05214 Glioma
    103010512 (GRB2)
   05221 Acute myeloid leukemia
    103010512 (GRB2)
   05220 Chronic myeloid leukemia
    103010512 (GRB2)
   05211 Renal cell carcinoma
    103010512 (GRB2)
   05215 Prostate cancer
    103010512 (GRB2)
   05213 Endometrial cancer
    103010512 (GRB2)
   05224 Breast cancer
    103010512 (GRB2)
   05223 Non-small cell lung cancer
    103010512 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    103010512 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    103010512 (GRB2)
   05160 Hepatitis C
    103010512 (GRB2)
   05163 Human cytomegalovirus infection
    103010512 (GRB2)
   05165 Human papillomavirus infection
    103010512 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103010512 (GRB2)
   01522 Endocrine resistance
    103010512 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bacu04131]
    103010512 (GRB2)
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:bacu04990]
    103010512 (GRB2)
Membrane trafficking [BR:bacu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    103010512 (GRB2)
Domain-containing proteins not elsewhere classified [BR:bacu04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   103010512 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 103010512
NCBI-ProteinID: XP_007185733
UniProt: A0A384AEP8
LinkDB
Position
Un
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccaccgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagag
ctcaatgggaaagacggcttcatccccaagaattacatagaaatgaaaccgcatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcctttcttatccgagagagcgagagtgctcctggggatttctccctctccgtcaag
tttggaaatgatgtacagcacttcaaggtgctccgagatggggctggaaagtatttcctc
tgggtggtcaagttcaattctttgaatgagctggtagattatcacagatctacatccgtc
tccagaaaccagcagatatttctccgggacatagagcaggtgccacagcaaccgacgtac
gtccaagccctctttgactttgatccccaagaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgtttccacgcaattacgtcacccccgtgaaccggaacgtctaa

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