KEGG   Bos indicus (zebu cattle): 109558908
Entry
109558908         CDS       T04792                                 

Gene name
PTPN6
Definition
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X1
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu04520  Adherens junction
biu04630  JAK-STAT signaling pathway
biu04650  Natural killer cell mediated cytotoxicity
biu04660  T cell receptor signaling pathway
biu04662  B cell receptor signaling pathway
biu05140  Leishmaniasis
biu05205  Proteoglycans in cancer
biu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:biu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    109558908 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    109558908 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    109558908 (PTPN6)
   04660 T cell receptor signaling pathway
    109558908 (PTPN6)
   04662 B cell receptor signaling pathway
    109558908 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    109558908 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109558908 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    109558908 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:biu01009]
    109558908 (PTPN6)
Enzymes [BR:biu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     109558908 (PTPN6)
Protein phosphatases and associated proteins [BR:biu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    109558908 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 109558908
NCBI-ProteinID: XP_019815802
UniProt: A0A6P5BMN1
LinkDB
Position
5
AA seq 597 aa
MLSHGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSXLRVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKRTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEE
TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVVLQGRDSNIPG
SDYINANYVKNQLLGPDENAKTYIASQGCLEATVNDFWQMVWQENTCVIVMTTREVEKGR
NKCVPYWPEVGSQRVYGPYTVTNCGEHDTTEYKLRNLQVSPLENENLIREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGRESEYGN
ITYPPAMKNAHAKASRTSSKHREDVYENVHSKNKKEEKVKKQRSADKEKNKGSLKRK
NT seq 1794 nt   +upstreamnt  +downstreamnt
atgctgtcccatgggtggtttcaccgagacctcagtgggctggatgcggagaccctgctc
aagggccgaggggtccacggaagcttcctggcacggcccagccgcaagaaccagggtgac
ttctccctctccgtcagggttggggaccaggtgactcatattcggatccagaactctggg
gacttctacgatctgtatggaggggagaagttcgcaacgttgacrgagctggtggagtac
tacacgcagcagcagggtgttctacaggaccgagacggcactatcatccacctcaagtac
ccgctgaactgctcagaccccaccagtgagaggtggtaccatggccacatgtctggaggg
caggcagagactttgctgcaggccaagggggagccttggactttccttgtgcgtgagagc
ctcagccagcctggagattttgtgctgtccgtgctcagcgaccagcccaaggctggcccc
ggctcccygctcagagtcacccatatcaaagtcatgtgtgagggcggacgctacacagtg
gggggttcggagaccttcgacagcctcactgacctggtggagcatttcaagaggacgggg
atcgaggaggcctccggcgctttcgtctacctacggcagccatactatgccacgagggtg
aacgcggctgacattgagaaccgggtcttggaactgaacaagaagcaggagtcagaggag
acagccaaggccggcttctgggaggagtttgagagtctgcagaagcaggaggtgaaaaac
ttgcaccagcggctggaagggcagcggccagaaaacaagagcaagaaccgttacaagaac
atccttccgtttgaccacagtcgagtggtcctgcagggacgcgacagtaacatccctggg
tctgactacattaacgccaactatgtgaagaaccagctgctaggccctgatgagaacgct
aagacctacatcgccagccagggctgcctggaggccacggtcaacgacttttggcagatg
gtgtggcaggagaacacctgcgtcattgtcatgaccacccgggaggtggagaagggccgg
aacaaatgtgttccatactggccagaagtgggcagtcagcgtgtttacggaccctacacc
gtaaccaattgcggggaacacgacacaactgagtacaaactccgaaacttacaggtctcc
ccgctggaaaatgagaacctgattcgggagatttggcactaccagtacctgagctggcct
gatcacggggtccccagtgagcctgggggtgttctcagcttcctggaccagatcaaccag
cggcaggagagtctgcctcacgcagggcccatcatcgtgcattgcagcgccggcatcggc
cgcacgggcaccatcattgtcatcgacatgctcatggagagcatctccaccaagggcctg
gactgtgacatcgacatccagaagaccatccagatggtgcgggcccagcgctcgggcatg
gtgcagacggaggctcagtacaagttcatctacgtggccatcgcccagttcatcgagacc
accaagaagaagttggaggtcatgcagtcccagaagggccgggaatcggaatacgggaac
atcacctacccgccagcaatgaagaacgcccacgccaaggcctcccgcacctcctctaaa
cacagggaggacgtgtatgagaatgtgcacagtaagaacaagaaggaggagaaggtgaag
aaacagcggtcagcagacaaggagaagaacaagggctccttgaagaggaagtga

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