KEGG   Delphinapterus leucas (beluga whale): 111176702
Entry
111176702         CDS       T05885                                 

Gene name
PTPN6
Definition
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X1
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle04520  Adherens junction
dle04630  JAK-STAT signaling pathway
dle04650  Natural killer cell mediated cytotoxicity
dle04660  T cell receptor signaling pathway
dle04662  B cell receptor signaling pathway
dle05140  Leishmaniasis
dle05205  Proteoglycans in cancer
dle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    111176702 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    111176702 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    111176702 (PTPN6)
   04660 T cell receptor signaling pathway
    111176702 (PTPN6)
   04662 B cell receptor signaling pathway
    111176702 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    111176702 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111176702 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    111176702 (PTPN6)
Enzymes [BR:dle01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     111176702 (PTPN6)
Protein phosphatases and associated proteins [BR:dle01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    111176702 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase HGAL
Other DBs
NCBI-GeneID: 111176702
NCBI-ProteinID: XP_022433175
UniProt: A0A2Y9NJV6
LinkDB
Position
Unknown
AA seq 597 aa
MLSHGWFHRDLSGLDAETLLKGRGVNGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPDSPLRVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKRTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVVLQGRNSNIPG
SDYINANYVKNQLLGPDENAKTYIASQGCLEATVNDFWQMVWQENTRVVVMTTREVEKGR
NKCVPYWPEVGTQHVYGLYAVTNCREHDAAEYKLRTLQVSPLDNGDLVREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGWESEYGN
ITYPPAMKNAHAKAARTSSKHKEDVYENVHSKNKKGEKVKKQRSADKEKSKGSLKRK
NT seq 1794 nt   +upstreamnt  +downstreamnt
atgctgtcccatgggtggtttcaccgagacctcagtgggctggatgccgagaccctgctc
aagggccgaggggtcaacgggagcttcctggctcggcccagtcgcaagaaccagggcgac
ttctccctctccgtcagggtgggggatcaggtgacccacattcggatccagaactcgggg
gatttctacgacctgtatggaggggagaagttcgcgacgctgacggagctggtggagtac
tacacgcagcagcagggcgtcctgcaggaccgcgacggcaccatcatccacctcaagtac
ccgctgaactgctcggaccccaccagtgagaggtggtaccatggccacatgtctggaggg
caggcagagacactgctgcaggccaagggtgagccctggacttttctcgtgcgtgaaagt
ctcagccagcctggagattttgtgctgtccgtgctcagcgaccagcccaaggctgggccg
gactccccgctcagagtcacccatatcaaggtcatgtgtgagggtggacgctacacagtg
ggcggttcggagaccttcgacagcctcacggacctggtggagcatttcaagaggacgggg
atcgaggaggcctcgggcgccttcgtctacctgcggcagccgtactacgctacgagggtg
aacgcagctgacattgagaaccgggtcttggaactgaacaagaagcaggagtcggaggac
acagccaaggctggcttctgggaggagtttgagagtctgcagaagcaggaggtgaagaac
ttgcaccagcggctggaagggcagcggccagaaaacaagagcaagaaccgttacaagaac
atccttccgttcgaccacagccgagtggtcctgcagggacgcaacagtaacatccctggg
tccgactacattaacgccaactacgtcaagaaccagctgctaggccctgatgagaatgct
aagacctacatcgccagccagggctgcctggaggccacagtcaacgacttctggcagatg
gtgtggcaggagaacacccgtgtcgtcgtcatgaccacccgggaggtggagaagggccgg
aacaaatgtgtcccatactggccagaggtgggcactcagcacgtttatggactctacgct
gtaaccaactgcagggaacacgacgcagctgagtacaaactccgcaccttacaggtctcc
ccgctggacaatggggacctggttcgggagatctggcactaccagtacctgagctggcct
gaccacggggtccccagcgagcctgggggtgtcctcagcttcctggaccagatcaaccag
cggcaggaaagtctgcctcacgcagggcccatcatcgtgcactgcagcgccggcattggc
cgcaccggcaccatcattgtcatcgacatgcttatggagagcatctccaccaagggcctg
gactgtgacatcgacatccagaagacgatccagatggtacgggcccagcgctcgggcatg
gtgcagacggaggcgcagtacaagttcatctacgtggccatcgcccagttcatcgaaacc
accaagaagaagctggaggtcatgcagtcccagaagggctgggagtcggagtacgggaac
attacctaccccccagccatgaagaatgcccatgccaaggccgcccgcacctcctccaaa
cacaaggaggacgtgtatgagaacgtgcacagtaagaacaagaagggcgagaaggtgaag
aagcagcggtcggcggacaaggagaagagcaagggttccctgaagaggaagtga

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