| Entry |
|
|---|
| Name |
Fentanyl (JAN/USP/INN);
Duragesic (TN);
Subsys (TN)
|
|---|
| Product |
|
|---|
| Generic |
FENTANYL SYSTEM (Alvogen), FENTANYL (Apotex Corp.), FENTANYL (Apotex Corp.), FENTANYL (Bryant Ranch Prepack), FENTANYL (Bryant Ranch Prepack), FENTANYL (Bryant Ranch Prepack), FENTANYL (DirectRX), FENTANYL (DirectRX), FENTANYL (Lake Erie Medical DBA Quality Care Products LLC), FENTANYL (Mylan Pharmaceuticals), FENTANYL (Quality Care Products), FENTANYL (Quality Care Products), FENTANYL (Quality Care Products) |
|---|
| Formula |
C22H28N2O
|
|---|
| Exact mass |
336.2202
|
|---|
| Mol weight |
336.4705
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 8219 |
| Product (DG00791): | D00320<JP/US> D01399<JP/US> |
|
|---|
| Efficacy |
Analgesic (narcotic), Opioid receptor agonist |
|---|
| Comment |
synthetic-opioid
Phenylpiperidine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AH Opioid anesthetics
N01AH01 Fentanyl
D00320 Fentanyl (JAN/USP/INN) <JP/US>
N02 ANALGESICS
N02A OPIOIDS
N02AB Phenylpiperidine derivatives
N02AB03 Fentanyl
D00320 Fentanyl (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Analgesics
Opioid Analgesics, Long-acting
Fentanyl
D00320 Fentanyl (JAN/USP/INN)
Opioid Analgesics, Short-acting
Fentanyl
D00320 Fentanyl (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
8 Narcotics
82 Non-alkaloidal narcotics
821 Synthetic narcotics
8219 Others
D00320 Fentanyl (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D00320 Fentanyl (JAN/USP/INN) <JP/US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00320
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 25
1 N1c N 28.2800 -14.2100
2 C1y C 29.5400 -14.9100
3 C8y C 27.0900 -14.9100
4 C5a C 28.2800 -12.8100
5 C1x C 29.5400 -16.3100
6 C1x C 30.7300 -14.2100
7 C8x C 25.9000 -14.2100
8 C8x C 27.0900 -16.3100
9 C1b C 29.5400 -12.1100
10 O5a O 27.0900 -12.1100
11 C1x C 30.7300 -17.0100
12 C1x C 31.9200 -14.9100
13 C8x C 24.6400 -14.9100
14 C8x C 25.8300 -17.0100
15 C1a C 30.7300 -12.8100
16 N1y N 31.9200 -16.3100
17 C8x C 24.6400 -16.2400
18 C1b C 33.1800 -17.0100
19 C1b C 34.3700 -16.3100
20 C8y C 35.5600 -17.0100
21 C8x C 35.5600 -18.4100
22 C8x C 36.8200 -16.3100
23 C8x C 36.8200 -19.1100
24 C8x C 38.0100 -17.0100
25 C8x C 38.0100 -18.4100
BOND 27
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 1
9 4 10 2
10 5 11 1
11 6 12 1
12 7 13 1
13 8 14 2
14 9 15 1
15 11 16 1
16 13 17 2
17 16 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 20 22 2
22 21 23 2
23 22 24 1
24 23 25 1
25 12 16 1
26 14 17 1
27 24 25 2
|
|---|
