| Entry |
|
|---|
| Name |
Plecanatide (USAN/INN);
Trulance (TN)
|
|---|
| Product |
|
|---|
| Formula |
C65H104N18O26S4
|
|---|
| Exact mass |
1680.6252
|
|---|
| Mol weight |
1681.8863
|
|---|
| Sequence |
Asn Asp Glu Cys Glu Leu Cys Val Asn Val Ala Cys Thr Gly Cys Leu
(Disulfide bridge: 4-12, 7-15) |
|---|
| Type |
Peptide |
|---|
| Remark |
|
|---|
| Efficacy |
Peristaltic accelerator, Enterotoxin receptor agonist |
|---|
| Disease |
Irritable bowel syndrome [DS: H01615] |
|---|
| Comment |
synthetic analog of Uroguanylin [CPD: C16006]
Chronic constipation, irritable bowel syndrome with constipation
|
|---|
| Target |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A06 DRUGS FOR CONSTIPATION
A06A DRUGS FOR CONSTIPATION
A06AX Other drugs for constipation
A06AX07 Plecanatide
D09948 Plecanatide (USAN/INN) <US>
USP drug classification [BR:br08302]
Gastrointestinal Agents
Anti-Constipation Agents
Plecanatide
D09948 Plecanatide (USAN/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Lyases (EC4)
Phosphorus-oxygen lyases
GUCY2C
D09948 Plecanatide (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D09948
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D09948
 |
|---|
| Other DBs |
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|---|
| LinkDB |
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