KEGG   ORTHOLOGY: K12320
Entry
K12320                      KO                                     

Symbol
GUCY2C
Name
heat-stable enterotoxin receptor [EC:4.6.1.2]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
Disease
H01174  Congenital diarrhea
H01615  Irritable bowel syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K12320  GUCY2C; heat-stable enterotoxin receptor
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K12320  GUCY2C; heat-stable enterotoxin receptor
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.2  guanylate cyclase
     K12320  GUCY2C; heat-stable enterotoxin receptor
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  RGC family [OT]
   K12320  GUCY2C; heat-stable enterotoxin receptor
Other DBs
RN: R00434
GO: 0004383
Genes
HSA: 2984(GUCY2C)
PTR: 473375(GUCY2C)
PPS: 100975209(GUCY2C)
GGO: 101138030(GUCY2C)
PON: 100460918(GUCY2C)
NLE: 100594944(GUCY2C)
MCC: 699191(GUCY2C)
MCF: 102130850(GUCY2C)
CSAB: 103218671(GUCY2C)
CATY: 105585122(GUCY2C)
PANU: 101013490(GUCY2C)
RRO: 104666399(GUCY2C)
RBB: 108530463(GUCY2C)
TFN: 117090471(GUCY2C)
PTEH: 111552055(GUCY2C)
CJC: 100406002(GUCY2C)
SBQ: 101038981(GUCY2C)
MMUR: 105865281(GUCY2C)
MMU: 14917(Gucy2c)
MCAL: 110296529(Gucy2c)
MPAH: 110316487(Gucy2c)
RNO: 25711(Gucy2c)
MCOC: 116098405(Gucy2c)
MUN: 110552758(Gucy2c)
CGE: 100757969(Gucy2c)
PLEU: 114695054(Gucy2c)
NGI: 103752330(Gucy2c)
HGL: 101720874(Gucy2c)
CCAN: 109696930(Gucy2c)
OCU: 100008740(GUCY2C)
OPI: 101523873(GUCY2C)
TUP: 102495739(GUCY2C)
CFA: 486671(GUCY2C)
VVP: 112917486(GUCY2C)
VLG: 121480133(GUCY2C)
AML: 100468576(GUCY2C)
UMR: 103677772(GUCY2C)
UAH: 113257858(GUCY2C)
ORO: 101382463(GUCY2C)
ELK: 111142267
MPUF: 101680691(GUCY2C)
EJU: 114221649(GUCY2C)
MLX: 118025633(GUCY2C)
FCA: 101095109(GUCY2C)
PYU: 121038884(GUCY2C)
PBG: 122473892(GUCY2C)
PTG: 102963095(GUCY2C)
PPAD: 109268647(GUCY2C)
AJU: 106965660(GUCY2C)
HHV: 120236860(GUCY2C)
BTA: 282244(GUCY2C)
BOM: 102284444(GUCY2C)
BIU: 109559629(GUCY2C)
BBUB: 102402674(GUCY2C)
CHX: 108636048(GUCY2C)
OAS: 101108212
ODA: 120858885(GUCY2C)
CCAD: 122423819(GUCY2C)
SSC: 397193(GUCY2C)
CFR: 102516411(GUCY2C)
CBAI: 105062249(GUCY2C)
CDK: 105096521(GUCY2C)
BACU: 103006662(GUCY2C)
LVE: 103081407(GUCY2C)
OOR: 101284028(GUCY2C)
DLE: 111176790(GUCY2C)
PCAD: 102978761(GUCY2C)
ECB: 100063810(GUCY2C)
EPZ: 103559389(GUCY2C)
EAI: 106826729(GUCY2C)
MYB: 102247939(GUCY2C)
MYD: 102772626(GUCY2C)
MMYO: 118649494(GUCY2C)
MNA: 107525360(GUCY2C)
HAI: 109383130(GUCY2C)
DRO: 112318447(GUCY2C)
SHON: 118978455(GUCY2C)
AJM: 119042841(GUCY2C)
MMF: 118624727(GUCY2C)
PALE: 102883474(GUCY2C)
PGIG: 120613746(GUCY2C)
RAY: 107508610(GUCY2C)
MJV: 108397788(GUCY2C)
TOD: 119247682(GUCY2C)
LAV: 100675825(GUCY2C)
TMU: 101340932
MDO: 100016988(GUCY2C)
SHR: 100925538(GUCY2C)
PCW: 110213823(GUCY2C)
OAA: 100091310(GUCY2C)
GGA: 417968(GUCY2C)
PCOC: 116233426(GUCY2C)
MGP: 100550786(GUCY2C)
CJO: 107313537(GUCY2C)
NMEL: 110392293(GUCY2C)
APLA: 101802157(GUCY2C)
ACYG: 106046052(GUCY2C)
TGU: 100228246(GUCY2C)
LSR: 110483071(GUCY2C)
SCAN: 103813321(GUCY2C)
PMOA: 120498350(GUCY2C)
OTC: 121342383(GUCY2C)
PRUF: 121361116(GUCY2C)
GFR: 102042400(GUCY2C)
FAB: 101816039(GUCY2C)
PHI: 102111535(GUCY2C)
PMAJ: 107204266(GUCY2C)
CCAE: 111934182(GUCY2C)
CCW: 104696375(GUCY2C)
ETL: 114064062(GUCY2C)
FPG: 101913205(GUCY2C)
FCH: 102053014(GUCY2C)
CLV: 102098904(GUCY2C)
EGZ: 104134274(GUCY2C)
NNI: 104021662(GUCY2C)
ACUN: 113491559(GUCY2C)
PADL: 103915916(GUCY2C)
AAM: 106488668(GUCY2C)
AROW: 112967708(GUCY2C)
NPD: 112948190(GUCY2C)
DNE: 112984535(GUCY2C)
ASN: 102374400(GUCY2C)
AMJ: 102558504(GUCY2C)
CPOO: 109316840(GUCY2C)
GGN: 109295825(GUCY2C)
PSS: 102444148(GUCY2C)
CMY: 102947911(GUCY2C)
CPIC: 101940459 101941251(GUCY2C)
TST: 117873400(GUCY2C)
CABI: 116838131(GUCY2C) 116838132
ACS: 100563369(gucy2c)
PVT: 110076095(GUCY2C)
PBI: 103067773(GUCY2C)
PMUR: 107302973(GUCY2C)
TSR: 106539270
PGUT: 117655724(GUCY2C)
PMUA: 114605114(GUCY2C)
ZVI: 118090801(GUCY2C)
GJA: 107118370(GUCY2C)
XLA: 108715011(gucy2c.S) 378662(gucy2c.L)
XTR: 100486678(gucy2c)
DRE: 568219(si:ch73-139e5.4) 572052(gucy2c)
IPU: 108272812(GUCY2C) 108273417
PHYP: 113527433(gucy2c) 113534683
AMEX: 103035855(gucy2c) 103043322
LCO: 104918929 104932052(gucy2c)
ELY: 117246769(si:ch73-139e5.4) 117268026(gucy2c)
PLEP: 121957007(gucy2ca) 121959101
SLUC: 116048739(si:ch73-139e5.4) 116065356(gucy2c)
ECRA: 117937134(si:ch73-139e5.4) 117957487(gucy2c)
GAT: 120819861(gucy2cb) 120828300(gucy2ca)
PPUG: 119212556(si:ch73-139e5.4) 119220890(gucy2c)
MSAM: 119884739(gucy2c) 119915580(si:ch73-139e5.4)
CUD: 121503561(gucy2ca) 121528353(gucy2cb)
OAU: 116327271(gucy2cb) 116327864(gucy2ca)
OLA: 100125818(olgc9) 100125820(olgc6)
OML: 112146531(gucy2c) 112154200(si:ch73-139e5.4)
CVG: 107089523 107093098(gucy2c)
CTUL: 119793772(si:ch73-139e5.4) 119799351(gucy2c)
NFU: 107376314(gucy2c) 107395148
KMR: 108235883(si:ch73-139e5.4) 108236050(gucy2c)
ALIM: 106520689(gucy2c) 106532355
XGL: 120793937(gucy2cb) 120806797(gucy2ca)
BPEC: 110159629 110162279(gucy2c)
MALB: 109952646
OMY: 110485178 110499093(si:ch73-139e5.4) 110502872 110538365
ELS: 105025088 105025779(gucy2c)
AANG: 118216790(gucy2c) 118220888(si:ch73-139e5.4)
LOC: 102697444(gucy2c)
PSPA: 121306199
LCM: 102346928(GUCY2C)
CMK: 103172259
RTP: 109919097(gucy2c)
 » show all
Reference
PMID:1718270
  Authors
Singh S, Singh G, Heim JM, Gerzer R
  Title
Isolation and expression of a guanylate cyclase-coupled heat stable enterotoxin receptor cDNA from a human colonic cell line.
  Journal
Biochem Biophys Res Commun 179:1455-63 (1991)
DOI:10.1016/0006-291X(91)91736-V
  Sequence
[hsa:2984]
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