KEGG   DRUG: シプロフロキサシン塩酸塩水和物
エントリ  
D02216                      Drug                                   

一般名   
シプロフロキサシン塩酸塩水和物 (JP17);
塩酸シプロフロキサシン;
シプロフロキサシン一塩酸塩一水和物;
Ciprofloxacin hydrochloride (USP);
Ciprofloxacin hydrochloride hydrate (JP17)
商品名   
  後発品
米国の商品 
  後発品
CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (Actavis Pharma), CIPROFLOXACIN (American Health Packaging), CIPROFLOXACIN (Aphena Pharma Solutions - Tennessee), CIPROFLOXACIN (AvKARE), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Cardinal Health), CIPROFLOXACIN (Clinical Solutions Wholesale), CIPROFLOXACIN (DIRECT RX), CIPROFLOXACIN (Denton Pharma), CIPROFLOXACIN (Denton Pharma), CIPROFLOXACIN (Denton Pharma), CIPROFLOXACIN (Denton Pharma), CIPROFLOXACIN (Denton Pharma), CIPROFLOXACIN (Direct_Rx), CIPROFLOXACIN (Direct_Rx), CIPROFLOXACIN (Direct_Rx), CIPROFLOXACIN (Dr. Reddy's Laboratories Limited), CIPROFLOXACIN (Golden State Medical Supply), CIPROFLOXACIN (Hikma Pharmaceuticals USA), CIPROFLOXACIN (Lake Erie Medical DBA Quality Care Products LLC), CIPROFLOXACIN (Leading Pharma), CIPROFLOXACIN (Major Pharmaceuticals), CIPROFLOXACIN (Medsource Pharmaceuticals), CIPROFLOXACIN (Medsource Pharmaceuticals), CIPROFLOXACIN (Medsource Pharmaceuticals), CIPROFLOXACIN (Method Pharmaceuticals), CIPROFLOXACIN (Mylan Pharmaceuticals), CIPROFLOXACIN (NCS HealthCare of KY), CIPROFLOXACIN (NCS HealthCare of KY), CIPROFLOXACIN (NuCare Pharmaceuticals), CIPROFLOXACIN (NuCare Pharmaceuticals), CIPROFLOXACIN (NuCare Pharmaceuticals), CIPROFLOXACIN (NuCare Pharmaceuticals), CIPROFLOXACIN (NuCare Pharmaceuticals), CIPROFLOXACIN (NuCare Pharmaceuticals), CIPROFLOXACIN (NuCare Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PharmPak), CIPROFLOXACIN (PharmPak), CIPROFLOXACIN (Preferred Pharmaceuticals), CIPROFLOXACIN (Preferred Pharmaceuticals), CIPROFLOXACIN (Preferred Pharmaceuticals), CIPROFLOXACIN (Proficient Rx LP), CIPROFLOXACIN (Proficient Rx LP), CIPROFLOXACIN (Proficient Rx LP), CIPROFLOXACIN (Proficient Rx LP), CIPROFLOXACIN (Quality Care Products), CIPROFLOXACIN (Quality Care Products), CIPROFLOXACIN (REMEDYREPACK), CIPROFLOXACIN (REMEDYREPACK), CIPROFLOXACIN (REMEDYREPACK), CIPROFLOXACIN (REMEDYREPACK), CIPROFLOXACIN (REMEDYREPACK), CIPROFLOXACIN (RPK Pharmaceuticals), CIPROFLOXACIN (RPK Pharmaceuticals), CIPROFLOXACIN (RedPharm Drug), CIPROFLOXACIN (RedPharm Drug), CIPROFLOXACIN (RedPharm Drug), CIPROFLOXACIN (RedPharm Drug), CIPROFLOXACIN (RedPharm Drug), CIPROFLOXACIN (RedPharm Drug), CIPROFLOXACIN (RedPharm Drug), CIPROFLOXACIN (Rising Pharmaceuticals), CIPROFLOXACIN (St Marys Medical Park Pharmacy), CIPROFLOXACIN (medsource pharmaceuticals), CIPROFLOXACIN (medsource pharmaceuticals), CIPRO (Advanced Rx Pharmacy of Tennessee), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (A-S Medication Solutions), CIPROFLOXACIN (Akorn), CIPROFLOXACIN HCL OPHTHALMIC (Altaire Pharmaceuticals), CIPROFLOXACIN (American Health Packaging), CIPROFLOXACIN (Aphena Pharma Solutions - Tennessee), CIPROFLOXACIN (Aphena Pharma Solutions - Tennessee), CIPROFLOXACIN (Asclemed USA), CIPROFLOXACIN (Aurobindo Pharma Limited), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (CHARTWELL GOVERNMENTAL & SPECIALTY RX LLC), CIPROFLOXACIN (Cardinal Health), CIPROFLOXACIN (Carlsbad Technology), CIPROFLOXACIN (DIRECT RX), CIPROFLOXACIN (Denton Pharma), CIPROFLOXACIN (Henry Schein), CIPROFLOXACIN (Lake Erie Medical DBA Quality Care Products LLC), CIPROFLOXACIN (Mckesson Corporation DBA SKY Packaginng), CIPROFLOXACIN (Medsource Pharmaceuticals), CIPROFLOXACIN (NorthStar Rx LLC), CIPROFLOXACIN (NuCare Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (PD-Rx Pharmaceuticals), CIPROFLOXACIN (Preferred Pharmaceuticals), CIPROFLOXACIN HYDROCHLORIDE (Preferred Preferred Phamraceuticals Inc.), CIPROFLOXACIN (Proficient Rx LP), CIPROFLOXACIN HYDROCHLORIDE (Proficient Rx LP), CIPROFLOXACIN (Quality Care Products), CIPROFLOXACIN HYDROCHLORIDE (RPK Pharmaceuticals), CIPROFLOXACIN (RPK Pharmaceuticals), CIPROFLOXACIN (RedPharm Drug), CIPROFLOXACIN HYDROCHLORIDE (Sandoz), CIPROFLOXACIN (Taro Pharmaceuticals U.S.A.), CIPROFLOXACIN HYDROCHLORIDE (medsource pharmaceuticals), CIPROFLOXACIN (DIRECT RX), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Bryant Ranch Prepack), CIPROFLOXACIN (Denton Pharma), CIPROFLOXACIN (Preferred Pharmaceutical), CIPROFLOXACIN (Preferred Pharmaceuticals), CIPROFLOXACIN (REMEDYREPACK), CIPROFLOXACIN (St Mary's Medical Park Pharmacy), CIPROFLOXACIN (Yiling Pharmaceutical)
組成式   
C17H18FN3O3. HCl. H2O
質量    
385.1205
分子量   
385.8177
構造式   
Simcomp   
クラス   
抗菌薬
 DG01550  キノロン系抗生物質
  DG01549  フルオロキノロン系抗生物質
その他
 DG01529  トポイソメラーゼ阻害薬
  DG01528  トポイソメラーゼIV阻害薬
代謝酵素阻害薬
 DG01634  CYP1A2阻害薬
コード   
同一コード: C13993
薬効分類: 6241
ATCコード: J01MA02 S01AE03 S02AA15 S03AA07
化学構造グループ: DG00617
商品 (DG00617): D00186<JP/US> D02216<JP/US>
商品 (mixture): D10296<US> D11089<US> D11582<US>
効能    
抗菌薬, 核酸合成阻害薬
  疾患
胆のう炎 [DS:H01213]
炭疽 [DS:H00328]
ターゲット 
DNA gyrase [KO:K02469 K02470]
相互作用  
CYP inhibition: CYP1A2 [HSA:1544]

構造マップ 
map07014  キノロン系
他のマップ 
map04976  胆汁の分泌
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 6  病原生物に対する医薬品
  62  化学療法剤
   624  合成抗菌剤
    6241  ピリドンカルボン酸系製剤
     D02216  シプロフロキサシン塩酸塩水和物 (JP17); 塩酸シプロフロキサシン; シプロフロキサシン一塩酸塩一水和物
医療用医薬品のATC分類 [BR:jp08303]
 J 全身用抗感染薬
  J01 全身用抗菌薬
   J01M キノロン系抗菌薬
    J01MA フルオロキノロン
     J01MA02 シプロフロキサシン
      D02216  シプロフロキサシン塩酸塩水和物 (JP17) <JP/US>
 S 感覚器
  S01 眼科用薬
   S01A 抗感染薬
    S01AE フルオロキノロン
     S01AE03 シプロフロキサシン
      D02216  シプロフロキサシン塩酸塩水和物 (JP17) <JP/US>
  S02 耳科用薬
   S02A 抗感染薬
    S02AA 抗感染薬
     S02AA15 シプロフロキサシン
      D02216  シプロフロキサシン塩酸塩水和物 (JP17) <JP/US>
  S03 眼科・耳科用製剤
   S03A 抗感染薬
    S03AA 抗感染薬
     S03AA07 シプロフロキサシン
      D02216  シプロフロキサシン塩酸塩水和物 (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗菌薬
  キノロン系抗菌薬
   シプロフロキサシン
    D02216  シプロフロキサシン塩酸塩水和物 (JP17)
 眼科用薬
  眼科用抗感染症薬
   抗菌薬, 眼科用薬
    シプロフロキサシン
     D02216  シプロフロキサシン塩酸塩水和物 (JP17)
 耳鼻科用薬
  耳鼻科用抗感染症薬
   シプロフロキサシン
    D02216  シプロフロキサシン塩酸塩水和物 (JP17)
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D02216  シプロフロキサシン塩酸塩水和物
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D02216
リンク   
CAS: 86393-32-0
PubChem: 7849275
ChEBI: 59936
ChEMBL: CHEMBL4303345
DrugBank: DB00537
LigandBox: D02216
日化辞: J245.528E
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