Entry
Name
6-hydroxyhexanoate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
6-hydroxyhexanoate:NAD+ oxidoreductase
Reaction(IUBMB)
6-hydroxyhexanoate + NAD+ = 6-oxohexanoate + NADH + H+ [RN:
R05283 ]
Reaction(KEGG)
Substrate
Product
Comment
Involved in the cyclohexanol degradation pathway in Acinetobacter NCIB 9871.
History
EC 1.1.1.258 created 2000
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K19961 6-hydroxyhexanoate dehydrogenase
Genes
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Taxonomy
Reference
Authors
Donoghue NA, Trudgill PW.
Title
The metabolism of cyclohexanol by Acinetobacter NCIB 9871.
Journal
Reference
Authors
Hecker LI, Tondeur Y, Farrelly JG.
Title
Formation of epsilon-hydroxycaproate and epsilon-aminocaproate from N-nitrosohexamethyleneimine: evidence that microsomal alpha-hydroxylation of cyclic nitrosamines may not always involve the insertion of molecular oxygen into the substrate.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.258
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.258
LinkDB
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