| Entry |
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| Name |
geraniol dehydrogenase (NAD+);
GeDH;
geoA (gene name)
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
geraniol:NAD+ oxidoreductase
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| Reaction(IUBMB) |
geraniol + NAD+ = geranial + NADH + H+ [RN: R10308]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme from the bacterium Castellaniella defragrans is most active in vitro with perillyl alcohol [2]. The enzyme from the prune mite Carpoglyphus lactis also acts (more slowly) on farnesol but not on nerol [1].
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| History |
EC 1.1.1.347 created 2013
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| Pathway |
| ec01130 | Biosynthesis of antibiotics |
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| Orthology |
| K19653 | geraniol dehydrogenase (NAD+) |
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| Genes |
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| Reference |
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| Authors |
Noge K, Kato M, Mori N, Kataoka M, Tanaka C, Yamasue Y, Nishida R, Kuwahara Y |
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| Title |
Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae). |
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| Journal |
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| Reference |
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| Authors |
Luddeke F, Wulfing A, Timke M, Germer F, Weber J, Dikfidan A, Rahnfeld T, Linder D, Meyerdierks A, Harder J |
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| Title |
Geraniol and geranial dehydrogenases induced in anaerobic monoterpene degradation by Castellaniella defragrans. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.1.1.347 |
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| LinkDB |
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