KEGG   ENZYME: 1.1.1.367
Entry
EC 1.1.1.367                Enzyme                                 
Name
UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase;
WbjC;
Cap5F
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
UDP-2-acetamido-2,6-dideoxy-L-talose:NADP+ oxidoreductase
Reaction(IUBMB)
UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NAD(P)+ = UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose + NAD(P)H + H+ [RN:R10665]
Reaction(KEGG)
R10665;
(other) R12552 R12553
Substrate
UDP-2-acetamido-2,6-dideoxy-beta-L-talose [CPD:C20768];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose;
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Part of the biosynthesis of UDP-N-acetyl-L-fucosamine. Isolated from the bacteria Pseudomonas aeruginosa and Staphylococcus aureus.
History
EC 1.1.1.367 created 2014
Pathway
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K19068  UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase
Genes
EOJ: ECO26_2944(fnlB)
ECOO: ECRM13514_2753(fnlB)
ECOH: ECRM13516_2621(fnlB)
EAB: ECABU_c23610(fnlB)
ELP: P12B_c2137(capF)
SBZ: A464_2212
SBV: N643_09265
ECAN: CWI88_07915
CUI: AFK65_12840
CTU: CTU_27300
CFAR: CI104_16435
CIE: AN232_13735 AN232_31060
LEA: GNG26_14690
BFT: MNO13_08025
YFR: AW19_2184
YKR: CH54_3602
YKI: HRD70_21635
PALH: B1H58_14580
PGZ: C2E15_13435
MHAN: K6958_13120
PTT: VY86_07665
ASY: AUT07_00149(fcl)
OPO: DSM2777_17405
HPAS: JL26_05870
PMU: PM1008(wbjC)
PMV: PMCN06_0222(wbjC)
PUL: NT08PM_0219
PMP: Pmu_01530(wbjC)
PMUL: DR93_961
PDAG: 4362423_00268(wbjC)
LLZ: LYB30171_02307(wbjC)
LUS: E5843_03575
THES: FHQ07_00275
THEH: G7079_07105
VCZ: VAB027_3591
VSI: MTO69_00765
VFL: AL536_19550
VTA: A2995
VNP: KW548_01100
VLE: ISX51_00535
VFI: VF_0192(fnlB)
PMAI: CF386_03165
SPRO: N7E60_09570
PAP: PSPA7_1981
PNC: NCGM2_4270(wbjC)
PAEB: NCGM1900_3148(wbjC)
PSG: G655_09070
PAEU: BN889_06737
PPAA: B7D75_09290
PPG: PputGB1_1374
PPUH: B479_06960
PMOL: CLJ08_05530
PMOS: O165_002650
PCI: PCH70_40500
PLIJ: KQP88_19080
PFS: PFLU_1658(fnl2)
PMAN: OU5_1708
PTV: AA957_05810
PMED: E3Z27_08410
PFW: PF1751_v1c16220
PFF: PFLUOLIPICF700210
PEN: PSEEN1501
PBA: PSEBR_a1566
PFZ: AV641_08230
PSEC: CCOS191_3871
PUM: HGP31_08955
PPSH: G5J76_11625
PVK: EPZ47_08540
PMAO: PMYSY11_1868(wbjC)
PTRT: HU722_0009235
PXN: HU772_006860
PFAK: KSS94_07160
PORY: EJA05_07540
PHYG: JTY93_09010
PSJY: AA098_07555
PKG: LW136_14055
HAES: LO767_04840
PNN: KEM63_05740
DCE: O6P33_12005
PBAU: OS670_00930
MBS: MRBBS_2501
MLQ: ASQ50_04330
MARA: D0851_05375
MSAN: LPB19_15020
PALI: A3K91_0727
PSYP: E5677_09750
ABZ: ABZJ_00088
ABR: ABTJ_03753
ABAD: ABD1_00590
ABAB: BJAB0715_00105
ABAU: IX87_14885
ABAL: ABLAC_36950
AHL: AHTJS_16405
AID: CTZ23_14895
ABER: BSR55_00410
AVB: RYU24_00890(fnlB)
SBP: Sbal223_1481
SJA: SJ2017_1340
SHEJ: MZ182_13320
PNG: PNIG_a0508
PMAA: CPA52_14015
ASEM: NNL22_10180
PMAW: MACH26_31900(fnlB)
MPAF: R5R33_17150
FTD: AS84_1079
FTY: CH70_511
FCF: FNFX1_1463
FCN: FN3523_1490
FPH: Fphi_1263
FPT: BZ13_740
FPI: BF30_1511
FPX: KU46_48
FHA: CDV26_09050
FRC: KX01_1760(capF)
TXA: HQN79_09385
TANI: J8380_09240
TWN: L2Y54_20545
CYS: NYP54_03775
TEE: Tel_08635
THIM: KFB96_06175
APAC: S7S_10530
MPRF: J8N69_05375
NIK: F5I99_05205
EMP: EZMO1_2312
PLEI: Q9312_18920
AAJ: BOQ57_14820
AVR: B565_2780
OCE: GU3_12825
ZDF: AN401_12710
ACRS: LVJ80_06730
DTK: K4H28_02550
CFON: HZU75_02535
CPAU: EHF44_09265
PDQ: CL55_00003260
PANI: DCO16_01735
PPNO: DA70_17325
PPNM: LV28_13500
PRB: X636_09595
POX: MB84_03550
CABA: SBC2_28930(wbjC)
AXY: AXYL_06295
AIS: BUW96_24745
APES: FOC84_13785
AALN: Q3V95_12060
AAQU: D3M96_17705
ODI: ODI_R2816
PACR: FXN63_16085
PARK: LSG25_14390
RAC: RA876_17040
AJS: Ajs_3029
ACIP: CBP36_03065
ACIS: CBP35_15875
VBO: CKY39_06060
COF: FOZ74_09625
CBX: Cenrod_0493
HYR: BSY239_4260
HYB: Q5W_21530
HYN: F9K07_02085
SIMP: C6571_03420
CBAA: SRAA_0133
CBAB: SMCB_0540
KIA: G8A07_07110
EBA: ebA5887
AZA: AZKH_0898
TMZ: Tmz1t_3802
THK: CCZ27_21920
APP: CAP2UW1_0113
RHT: NT26_3156
SZO: K8M09_15615
BSEI: KMZ68_18920
SNO: Snov_3210
HDN: Hden_0186
HDT: HYPDE_23133
DEA: FPZ08_13245
DEVO: H4N61_00950
DOY: JI749_13380
DRH: JI748_11450
MARU: FIU81_15470
PAMO: BAR1_15460
SMAG: AN936_18585
SPHO: C3E99_07080
SECH: B18_28745
SCAB: LZK98_15345
SHAN: PPZ50_17995
SFLA: SPHFLASMR4Y_02428(wbjC)
SPHL: LPB140_06515
BFW: B5J99_05775
PHAO: HF685_11060
SFLV: IC614_08760
ARUE: QQX03_02255
PHZ: CHX26_09060
MFN: Ga0123462_1142
SULG: FJR48_03845
SSEI: FJR45_01380 FJR45_04470
SMAS: HUE87_09305
PACO: AACT_2069
AMYT: AMYT_0911
HCJ: HCR_18440(capF)
GPI: GPICK_06385
GUR: Gura_1693
GBM: Gbem_1622(wbjC)
DEU: DBW_1517
DFL: DFE_2838
DTO: TOL2_C08120(capF)
DMM: dnm_096990
DEK: DSLASN_12280
SFU: Sfum_2863
AORY: AMOR_24340
BBA: Bd1694(capF)
BCR: BCAH187_A5443
BNC: BCN_5195
BTHU: YBT1518_33541
BFD: NCTC4823_03153
BACI: B1NLA3E_20920
OJD: NP439_10445
OON: NP440_10230
LYZ: DCE79_04810
HMN: HM131_05135
HAMY: MUO15_17195
VIL: CFK37_02115
VIM: GWK91_11145
BMUR: ABE28_016005
PPSR: I6J18_19580
PSYO: PB01_03865
PRD: F7984_17695
GRC: GI584_20435
SCIB: HUG20_11465
NMK: CHR53_26470
BOU: I5818_12875
SAU: SA0149(capF)
SAV: SAV0154(capF)
SAW: SAHV_0153(capF)
SAH: SaurJH1_0145
SAJ: SaurJH9_0140
SAM: MW0129(cap8F)
SAS: SAS0129
SAR: SAR0156(capF)
SAC: SACOL0141(cap5F)
SAX: USA300HOU_0168(cap5F)
SAA: SAUSA300_0157(cap5F)
SAO: SAOUHSC_00119
SAE: NWMN_0100(capF)
SAD: SAAV_0122(cap5F)
SUU: M013TW_0144
SUV: SAVC_00540
SUE: SAOV_0101
SUJ: SAA6159_00138(cap8F)
SUK: SAA6008_00132(cap5F)
SUC: ECTR2_111
SUT: SAT0131_00144
SUQ: HMPREF0772_10344
SUZ: MS7_0148(capF)
SUD: ST398NM01_0168
SUX: SAEMRSA15_01200(capF)
SUW: SATW20_01650(capF)
SUG: SAPIG0168
SUF: SARLGA251_01280(capF)
SAUA: SAAG_00637
SAUE: RSAU_000108(capF)
SAUN: SAKOR_00134
SAUS: SA40_0121(capF)
SAUU: SA957_0136(capF)
SAUG: SA268_0133(capF)
SAUZ: SAZ172_0164
SAUT: SAI1T1_2001090(cap5F)
SAUJ: SAI2T2_1001090(cap5F)
SAUK: SAI3T3_1001090(cap5F)
SAUQ: SAI4T8_1001090(cap5F)
SAUV: SAI7S6_1001090
SAUW: SAI5S5_1001080
SAUX: SAI6T6_1001090
SAUY: SAI8T7_1001090
SAUF: X998_0137
SAB: SAB0095(capF)
SUY: SA2981_0155(capF)
SAUB: C248_0143(capF)
SAUM: BN843_1600
SAUC: CA347_165
SAUR: SABB_01687(capF)
SAUI: AZ30_00810
SAUD: CH52_04955
SAMS: NI36_00705
SUH: SAMSHR1132_01280
SHA: SH0393(capF)
SHH: ShL2_00298(cap5F)
SLG: SLGD_00328
SLN: SLUG_03250(capF)
SHU: SHYC_02145
SAGQ: EP23_07990
SARL: SAP2_22730
SPIC: SAMEA4384060_1738
SSH: NCTC13712_00109
SDB: CNQ82_05965
STAS: HYI43_01750
SROT: ML435_00600
MVT: I6J10_00250
MACR: BHM04_11830
MEPI: KFV12_12050
MEQU: KFV11_10310
SHV: AAT16_04055
LGZ: NCTC10812_01730
EAT: EAT1b_1188
EAP: KB235_04665 KB235_04855
EAUR: NMQ00_03460
EPF: OE059_02800
PAEH: H70357_28055
PAEJ: H70737_24330
KYR: CVV65_01740
SOB: CSE16_04875
PLN: Plano_2327
PLL: I858_011150
PMAR: B0X71_14590
PLAY: DNR44_008530
LLR: llh_0475
SPN: SP_0359(cps4K)
SNM: SP70585_0426
EFD: EFD32_1894
EGA: AL523_16080
MPX: MPD5_1385
VFV: K5K99_13355
VIE: OL234_02465
AUN: AWM73_05385
AUI: APT62_03040
ASAN: AWM72_06995
ALOY: CJ190_005575
GSG: CYJ72_009460
FCT: NRE15_06265
CARC: NY10_927
CARN: FPV25_02520
JEP: BW721_05895
JAR: G7057_08180 G7057_08365
CCHV: BTM20_03715
CGAS: J1C67_09575
CCAA: KQH81_02655
CGEL: psyc5s11_50950
CTHD: CDO33_01150
HHJ: NQ487_03400
PROQ: P6M73_08125
FSA: C5Q98_00735
RCH: RUM_09630
FPR: FP2_31570
SVJ: NQ490_01355
TMEL: NOG13_00250
PALM: RBG61_13225
SLP: Slip_0164
DRS: DEHRE_09885
DRM: Dred_3032
AACX: DEACI_3856 DEACI_3920 DEACI_3923 DEACI_3975
ELM: ELI_4558
ELIM: B2M23_15715
AWI: CHL1_003283
ALKA: J0B03_04225
ACAE: HYG86_00815
ALAC: JYE50_05280
BPEN: NQ488_00585
CBAF: JS518_03690
BPB: bpr_I0350
BHU: bhn_I0406
BYL: A4V09_01945
CPY: Cphy_3503
HSD: SD1D_1290
PXV: FXF36_15580
ACEL: acsn021_22510 acsn021_22560
ACHT: bsdcttw_26930 bsdcttw_26950
RGN: RGna_12005
DFM: NQ560_02630
SSUN: H9Q77_13985
MFOR: NQ534_01355
CBIL: EUBC25_21150
CBAR: PATL70BA_0362(wbjC)
AMIC: Ami3637_06440
GFE: Gferi_11335
TMY: TEMA_39650(wbjC)
TEB: T8CH_2470
THYR: P4S50_04810
EAC: EAL2_c20140
TXY: Thexy_1803
AFT: BBF96_11320
CKI: Calkr_2280
CLC: Calla_0173
TIZ: RBU61_15530
PUF: UFO1_4150
ERH: ERH_0859
ERS: K210_02150
ERL: AOC36_02525
ERI: EEI45_05840
ERD: G7062_06980
EIO: H9L01_07865
EUC: EC1_12020
AARG: Aargi30884_24440
LCG: L3BBH23_17550
ERM: EYR00_04310
TSF: NQ543_04005 NQ543_06840 NQ543_08000
CALK: HUE98_16965
ACL: ACL_1044
AAXA: NCTC10138_00337
MBJ: KQ51_00735
CSTC: LK434_09630
EGD: GS424_003815
CMD: B841_09300
CPEG: CPELA_00510
CGK: CGERO_00500
CPSO: CPPEL_00485
CSUR: N24_0491
DIZ: CT688_13275
PSIC: J4E96_17160
AGY: ATC03_14105
MYL: C3E77_02890
AGG: C1N71_10855
MANT: BHD05_03280
ARU: ASPU41_19425
AJG: KKR91_12385
APN: Asphe3_25570
PSEY: GU243_10715
GNC: QQS42_06740
RSA: RSal33209_1612(capF)
CMUA: P8192_03275
KSE: Ksed_18630
CFL: Cfla_0760
JME: EEW87_010815
TED: U5C87_10850
DCO: SAMEA4475696_2247
AUS: IPK37_01965
MICG: GJV80_08200
TDF: H9L22_12380
PROP: QQ658_01130
NDK: I601_1757
NOI: FCL41_02135
NOO: FE634_12355
NDP: E2C04_02755
NSN: EXE58_10525
NPI: G7071_07150
MCAB: HXZ27_11020
MSAG: GCM10017556_43940
MCHL: PVK74_01490
MPRN: Q3V37_27855
PLK: CIK06_10365
PLAB: C6361_29210
PLAT: C6W10_06230
PSUU: Psuf_011570
FLH: EJ997_04865
DMR: Deima_2967
DPT: Deipr_2059
DPD: Deipe_0923
DEZ: DKM44_11275
DFC: DFI_17510
OBG: Verru16b_02063
RUL: UC8_50260
MFF: MFFC18_22180
PND: Pla175_07580(wbiB)
BMEI: Spa11_33920
PBU: L21SP3_00953
PBP: STSP1_00660
VBC: C5Q97_11320 C5Q97_18390
SPER: EW093_13165
SBU: SpiBuddy_0258
SASS: MUG09_01995
SCD: Spica_0525
LIL: LA_1644
LIE: LIF_A1330
LIC: LIC_12140
LIS: LIL_12274(wcaG3)
LMAY: DPV73_15785
LWL: FHG68_08490
LNO: MAL08_11050
LKR: FH602_15560
GEX: GETHOR_25490
FNC: HMPREF0946_01288
FPD: CTM68_07390
FVA: FV113G1_07630
FUL: C4N20_02505
FPEI: C4N17_00395
FHO: H9Q81_07405
FSU: Fisuc_2694
FSC: FSU_3261
BTH: BT_0382
BTHO: Btheta7330_02108 Btheta7330_02998
BFR: BF1107
BFG: BF638R_1089 BF638R_3769
BFB: VU15_04775
BHL: Bache_2245
BCEL: BcellWH2_04978
BHF: C3V43_13540
BUN: Bun01g_26120
BFE: K6V30_14845 K6V30_24440
BNO: K8P02_02075
BHUM: JXR92_012460
BFC: BacF7301_20295
BFIN: BFINE_35860
BVU: BVU_0694 BVU_1540
PBT: ING2E5B_0564
DYH: G7051_07330
PPN: Palpr_0958
PDI: BDI_3832
PARC: CI960_13475
PMER: INE87_00424(wbjC)
PGOL: K6V26_10520 K6V26_11950
PJO: LK449_12390
PFAI: NXY11_06855
BUY: D8S85_13780
BFH: F1611_15565
PRU: PRU_0102
PCOI: LK433_14505
ALQ: C7Y71_007845
RBC: BN938_0769 BN938_1959
TTZ: FHG85_00420
BACC: BRDCF_p1467
DORI: FH5T_21510
CPI: Cpin_4751
CHIH: GWR21_01125
NIA: A8C56_07980
SEDT: TEGAF0_25640(fnlB)
PCM: AY601_4544
PSTY: BFS30_06920
SHT: KO02_22560
SPHZ: E3D81_15985
SFAE: MUK51_19455
MDA: IPZ59_16905
AANH: G9X63_04175
ALS: DJ013_17375
MAQA: LAG90_12540
CHRW: KA713_20640
FPS: FP1286(fnlB)
FPC: FPSM_02198
FPY: FPG101_11015
FPQ: IB65_06065
FPV: IA03_06170
FPW: IA04_06075
FPK: IA06_06110
FBR: FBFL15_1033(fnlB)
FIN: KQS_03315(fnlB)
FGL: EM308_00745
FKI: FK004_09020
FEN: J0383_14325
FCB: LOS89_02635
FKE: MG292_05655
FCU: NOX80_07430
COC: Coch_1111
CCM: Ccan_23350
CAPH: CGC49_04775
MART: BTR34_14765
CLY: Celly_2635
CBAT: M666_12275
COMN: PBN93_13180
KDI: Krodi_2767
DDO: I597_2182
NDO: DDD_3541(fnlB)
POB: LPB03_07080
MYR: MYRA21_3294
MCLA: P3875_07145
TDI: AUW17_02390
TFI: PJJ26_03065
MESQ: C7H62_1057
MARX: INR76_09920
SINH: LS482_11755
ASAG: FGM00_01225
MLT: VC82_2498
FBQ: D1817_01460
ELZ: FCS00_14710
CIH: ATE47_11270
CHH: A0O34_14030
CIO: CEQ15_13470
CHRY: CEY12_09720
CHRZ: CO230_02260
CARH: EGY05_16415
CSHA: EG350_15240
CNK: EG343_08470
CJT: EG359_09455
CIL: EG358_16295
CGLE: NCTC11432_02310
CTAI: NCTC12078_01305
CTAK: 4412677_01081
CSAL: NBC122_00352(wbjC_1) NBC122_02873(wbjC_2)
CNP: M0D58_15510
CDAE: MUU74_09400
CCAB: PFY12_05400
CORA: N0B40_00650
CGAM: PFY09_07715
CHRA: F7R58_09375
CFLU: ODZ84_09060
CJG: NCTC13459_02733
CANT: NCTC13489_01522
KHI: EG338_06405
CBAU: H1R16_04185
CNR: EB819_08340
ESTE: HNV03_12265
BBAU: AEM51_06820
CLZ: BIU88_00470
PPH: Ppha_0559
THER: Y592_04250
FPE: Ferpe_0105
FIA: NA23_00520
FRR: IB67_01690
CABY: Cabys_3398
NMV: NITMOv2_3488
NLI: G3M70_09945
MFK: E2N92_02925
 » show all
Reference
1  [PMID:12464616]
  Authors
Kneidinger B, O'Riordan K, Li J, Brisson JR, Lee JC, Lam JS
  Title
Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucosamine biosynthetic pathway.
  Journal
J Biol Chem 278:3615-27 (2003)
DOI:10.1074/jbc.M203867200
  Sequence
[paeb:NCGM1900_3148]
Reference
2  [PMID:15778500]
  Authors
Mulrooney EF, Poon KK, McNally DJ, Brisson JR, Lam JS
  Title
Biosynthesis of UDP-N-acetyl-L-fucosamine, a precursor to the biosynthesis of lipopolysaccharide in Pseudomonas aeruginosa serotype O11.
  Journal
J Biol Chem 280:19535-42 (2005)
DOI:10.1074/jbc.M500612200
Reference
3  [PMID:18540063]
  Authors
Miyafusa T, Tanaka Y, Kuroda M, Ohta T, Tsumoto K
  Title
Expression, purification, crystallization and preliminary diffraction analysis of CapF, a capsular polysaccharide-synthesis enzyme from Staphylococcus aureus.
  Journal
Acta Crystallogr Sect F Struct Biol Cryst Commun 64:512-5 (2008)
DOI:10.1107/S174430910801213X
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.367
IUBMB Enzyme Nomenclature: 1.1.1.367
ExPASy - ENZYME nomenclature database: 1.1.1.367
BRENDA, the Enzyme Database: 1.1.1.367
LinkDB

DBGET integrated database retrieval system