KEGG   ENZYME: 1.1.1.373
Entry
EC 1.1.1.373                Enzyme                                 

Name
sulfolactaldehyde 3-reductase;
yihU (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase
Reaction(IUBMB)
2,3-dihydroxypropane-1-sulfonate + NAD+ = 2-hydroxy-3-oxopropane-1-sulfonate + NADH + H+ [RN:R10719]
Reaction(KEGG)
R10719
Substrate
2,3-dihydroxypropane-1-sulfonate [CPD:C20797];
NAD+ [CPD:C00003]
Product
2-hydroxy-3-oxopropane-1-sulfonate [CPD:C20798];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, characterized from the bacterium Escherichia coli, is involved in the degradation pathway of sulfoquinovose, the polar headgroup of sulfolipids found in the photosynthetic membranes of all higher plants, mosses, ferns, algae, and most photosynthetic bacteria, as well as the surface layer of some archaea.
History
EC 1.1.1.373 created 2014
Orthology
K08318  4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase
Genes
PXY: 105397329
ECO: b3882(yihU)
ECJ: JW3853(yihU)
ECD: ECDH10B_4072(yihU)
EBW: BWG_3552(yihU)
ECOK: ECMDS42_3321(yihU)
ECE: Z5420(yihU)
ECS: ECs4805
ECF: ECH74115_5329
ETW: ECSP_4938(yihU)
EOI: ECO111_4702(yihU)
EOJ: ECO26_4708(yihU)
EOH: ECO103_4289(yihU)
ESL: O3K_24495
ESO: O3O_00840
ESM: O3M_24415
EOK: G2583_4683(yihU)
ELH: ETEC_4152
ECP: ECP_4088
ENA: ECNA114_3975(yihU)
ECOS: EC958_4354(yihU)
ECY: ECSE_4165
ECR: ECIAI1_4082(yihU)
ECQ: ECED1_4582(yihU)
EUM: ECUMN_4409(yihU)
ECT: ECIAI39_3118(yihU)
EOC: CE10_4546(yihU)
EBR: ECB_03767(yihU)
EBL: ECD_03767(yihU)
EBE: B21_03716(yihU)
EBD: ECBD_4145
ECI: UTI89_C4463(yihU)
ECC: c4826(yihU)
ESE: ECSF_3733
EKF: KO11_03195(yihU)
EDJ: ECDH1ME8569_3753(yihU)
ELW: ECW_m4186(yihU)
ELL: WFL_20395(yihU)
ELC: i14_4419(yihU)
ELD: i02_4419(yihU)
ELF: LF82_610
ECOI: ECOPMV1_04237(garR_4)
ECOJ: P423_21510
ESZ: FEM44_09220(yihU)
STY: STY3855(yihU)
STT: t3598(yihU)
STM: STM4023(yihU)
SEO: STM14_4836(yihU)
SEY: SL1344_3969(yihU)
SEJ: STMUK_4006(yihU)
SEB: STM474_4200(yihU)
SEF: UMN798_4360(yihU)
SENR: STMDT2_38831(yihU)
SEND: DT104_40301(yihU)
SENI: CY43_21025
SPT: SPA3864(yihU)
SEK: SSPA3594
SEI: SPC_4126(yihU)
SEC: SCH_3913(yihU)
SHB: SU5_0119
SENS: Q786_19720
SED: SeD_A4411
SEG: SG3402(yihU)
SEL: SPUL_3649(yihU)
SEGA: SPUCDC_3635(yihU)
SET: SEN3811(yihU)
SENA: AU38_19695
SENO: AU37_19710
SENV: AU39_19730
SENQ: AU40_22020
SENL: IY59_20190
SEEP: I137_17525
SENE: IA1_19550
SBG: SBG_3540(yihU)
SBZ: A464_4064
SFL: SF3954(yihU)
SFX: S3792(yihU)
SFV: SFV_3617(yihU)
SFE: SFxv_4308(yihU)
SFN: SFy_5649
SFS: SFyv_5712
SFT: NCTC1_04280(yihU)
SSN: SSON_4048(yihU)
SBO: SBO_3887(yihU)
ENC: ECL_05103
ECLX: LI66_22510
ECLY: LI62_24595
ECLZ: LI64_21625
ECLO: ENC_00300
EEC: EcWSU1_04480(yihU)
ECHG: FY206_24275(yihU)
EBG: FAI37_07030(yihU)
ESA: ESA_04058
CSK: ES15_0037
CTU: CTU_41740(yihU)
CRO: ROD_38791
CKO: CKO_03131
CPOT: FOB25_10635(yihU)
CAMA: F384_21000
LER: GNG29_22755(yihU)
LEA: GNG26_22095(yihU)
AHN: NCTC12129_04955(garR_2)
YAL: AT01_41
RAA: Q7S_20720
PAM: PANA_3497(yihU)
PLF: PANA5342_0554(yihU)
PAJ: PAJ_2726(yihU)
PSTW: DSJ_21395
MTHI: C7M52_01008(yihU)
LRI: NCTC12151_00811(Hgd)
BFN: OI25_3878
BBR: BB4070
RBM: TEF_16385
PSF: PSE_2341(garR)
RID: RIdsm_01292(hgd_4)
SPKC: KC8_02205
SHUM: STHU_22030
SVC: STVA_25540(garR)
HTQ: FRZ44_48020(yihU)
 » show all
Reference
1  [PMID:24463506]
  Authors
Denger K, Weiss M, Felux AK, Schneider A, Mayer C, Spiteller D, Huhn T, Cook AM, Schleheck D
  Title
Sulphoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulphur cycle.
  Journal
Nature 507:114-7 (2014)
DOI:10.1038/nature12947
  Sequence
[eco:b3882]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.373
IUBMB Enzyme Nomenclature: 1.1.1.373
ExPASy - ENZYME nomenclature database: 1.1.1.373
BRENDA, the Enzyme Database: 1.1.1.373
LinkDB

DBGET integrated database retrieval system