KEGG   ENZYME: 2.1.1.355
Entry
EC 2.1.1.355                Enzyme                                 

Name
[histone H3]-lysine9 N-trimethyltransferase;
KMT1A (gene name);
KMT1B (gene name);
KMT1C (gene name);
KMT1D (gene name);
KMT1F (gene name);
MT8 (gene name);
SUV39H1 (gene name);
G9A (gene name);
EHMT1 (gene name);
PRDM2 (gene name)
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:[histone H3]-L-lysine9 N6-trimethyltransferase
Reaction(IUBMB)
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine9 = 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9 (overall reaction);
(1a) S-adenosyl-L-methionine + a [histone H3]-L-lysine9 = S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine9;
(1b) S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine9 = S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine9;
(1c) S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine9 = S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9
Reaction(KEGG)
(other) R03875 R04866 R04867
Substrate
S-adenosyl-L-methionine [CPD:C00019];
[histone H3]-L-lysine9;
[histone H3]-N6-methyl-L-lysine9;
[histone H3]-N6,N6-dimethyl-L-lysine9
Product
S-adenosyl-L-homocysteine [CPD:C00021];
[histone H3]-N6,N6,N6-trimethyl-L-lysine9;
[histone H3]-N6-methyl-L-lysine9;
[histone H3]-N6,N6-dimethyl-L-lysine9
Comment
This entry describes several enzymes that successively methylate the L-lysine9 residue of histone H3 (H3K9), ultimately generating a trimethylated form. These modifications influence the binding of chromatin-associated proteins. In general, the methylation of H3K9 leads to transcriptional repression of the affected target genes. cf. EC 2.1.1.367, [histone H3]-lysine9 N-methyltransferase, EC 2.1.1.368, [histone H3]-lysine9 N-dimethyltransferase, and EC 2.1.1.366, [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase.
History
EC 2.1.1.355 created 1976 as EC 2.1.1.43, modified 1982, modified 1983, part transferred 2019 to EC 2.1.1.355, modified 2020
Pathway
ec00310  Lysine degradation
ec01100  Metabolic pathways
Orthology
K11419  [histone H3]-lysine9 N-trimethyltransferase SUV39H
K11420  [histone H3]-lysine9 N-trimethyltransferase EHMT
K11432  [histone H3]-lysine9 N-trimethyltransferase PRDM2
K18494  [histone H3]-lysine9 N-trimethyltransferase SETDB2
Genes
HSA: 10919(EHMT2) 6839(SUV39H1) 7799(PRDM2) 79723(SUV39H2) 79813(EHMT1) 83852(SETDB2)
PTR: 107971148(SUV39H1) 452719(SETDB2) 462572(EHMT2) 464891(EHMT1) 466014(SUV39H2) 469125(PRDM2)
PPS: 100968253(EHMT1) 100977497(SUV39H1) 100982469(SUV39H2) 100986951(SETDB2) 100991724(EHMT2) 103782930(PRDM2)
GGO: 101125370(PRDM2) 101126338(SUV39H2) 101139808(EHMT2) 101141713(SETDB2) 101146540(SUV39H1) 101151843(EHMT1)
PON: 100172621(SUV39H1) 100436926(SUV39H2) 100436958(PRDM2) 100437576(SETDB2) 100449422(EHMT1) 100460372(EHMT2)
NLE: 100582767(PRDM2) 100584465(EHMT1) 100591032(SUV39H2) 100593118 100598636(SUV39H1) 100606578(EHMT2)
MCC: 697378(SUV39H2) 706277(SETDB2) 711040(SUV39H1) 715824(EHMT2) 716295(PRDM2) 721470(EHMT1)
MCF: 101926557(PRDM2) 102124788(SETDB2) 102125769(EHMT1) 102134179(SUV39H1) 102136014(SUV39H2) 102139754(EHMT2)
CSAB: 103214423(SETDB2) 103221737(EHMT2) 103225565(PRDM2) 103231938(SUV39H1) 103237926(SUV39H2) 103239544(EHMT1)
RRO: 104660660(SUV39H1) 104662745(SETDB2) 104664471(SUV39H2) 104669606(EHMT1) 104674046(PRDM2) 104678126(EHMT2)
RBB: 108517467(SUV39H1) 108519969 108520267(EHMT2) 108530731(SETDB2) 108531071(SUV39H2) 108542880(EHMT1)
CJC: 100385110(PRDM2) 100394788(SETDB2) 100398057(EHMT1) 100401369(SUV39H1) 100401513(SUV39H2) 100408867(EHMT2)
SBQ: 101040475(SUV39H2) 101043411(SETDB2) 101046305(EHMT2) 101052197(SUV39H1) 101054202(PRDM2) 101054241(EHMT1) 104652487
MMU: 107303348(Gm45935) 110147(Ehmt2) 110593(Prdm2) 20937(Suv39h1) 239122(Setdb2) 64707(Suv39h2) 77683(Ehmt1)
MCAL: 110284133(Ehmt2) 110287176(Suv39h1) 110289296(Suv39h2) 110293588(Prdm2) 110309030(Setdb2) 110312405(Ehmt1)
MPAH: 110313347(Suv39h1) 110317691(Ehmt1) 110322886(Prdm2) 110325326(Setdb2) 110333642(Suv39h2) 110335935(Ehmt2)
RNO: 100361710(Setdb2) 302553(Suv39h1) 313678(Prdm2) 361798(Ehmt2) 362078(Ehmt1) 364785(Suv39h2) 501653(RGD1565692)
MUN: 110554698(Suv39h2) 110556467(Prdm2) 110560108(Ehmt2) 110561991(Suv39h1)
CGE: 100754544(Ehmt1) 100755145(Suv39h2) 100764568(Suv39h1) 100769417(Ehmt2) 100774155(Setdb2) 103158597(Prdm2)
NGI: 103724422(Ehmt2) 103732609(Ehmt1) 103735184(Suv39h2) 103741644(Suv39h1) 103752332(Prdm2)
HGL: 101696702(Setdb2) 101697232(Ehmt2) 101699104(Ehmt1) 101699822(Prdm2) 101701917(Suv39h2) 101706867(Suv39h1)
CCAN: 109688969(Ehmt1) 109689573(Ehmt2) 109691104(Setdb2) 109691500(Suv39h2) 109701207(Suv39h1) 109702677(Prdm2)
OCU: 100342335(PHF11) 100348361(EHMT1) 100350859 100354725(SUV39H1) 100355131(EHMT2) 100358024(SUV39H2) 103352508(PRDM2)
TUP: 102468719(SUV39H1) 102472765 102479735(EHMT2) 102498729(EHMT1) 102499550(PRDM2) 102503290(SETDB2)
CFA: 100688431(PRDM2) 474851(EHMT2) 477995(SUV39H2) 485441(SETDB2) 491224(EHMT1) 491868(SUV39H1)
VVP: 112907242(SUV39H1) 112911417(EHMT1) 112913622(EHMT2) 112929764(PRDM2) 112933120(SUV39H2) 112933943(SETDB2)
AML: 100466861(EHMT1) 100468794(EHMT2) 100469547(SUV39H2) 100472595(SUV39H1) 100476962 100481446(PRDM2)
UMR: 103664189(SUV39H2) 103666633(PRDM2) 103666849 103669105(SUV39H1) 103675323(EHMT1) 103677615(SETDB2) 103682289(EHMT2)
UAH: 113241391(SUV39H2) 113243735(EHMT2) 113248390 113248430 113251315 113265922(SUV39H1) 113270485(PRDM2)
ORO: 101364966(PRDM2) 101374258(SUV39H2) 101375740(EHMT1) 101376988(EHMT2) 101381146(SUV39H1) 101381937(SETDB2)
FCA: 101082169(PRDM2) 101083571(SUV39H1) 101087111(EHMT1) 101091940(EHMT2) 101099218(SUV39H2)
PTG: 102950897(SUV39H1) 102954489(EHMT1) 102962904(SETDB2) 102963752(SUV39H2) 102966552 102967892(PRDM2) 102968259(EHMT2)
PPAD: 109248069(SUV39H1) 109260239(EHMT1) 109260503(EHMT2) 109265964 109273698(SUV39H2) 109274376(PRDM2)
AJU: 106970864(SUV39H1) 106971016(SUV39H2) 106972687 106983481(EHMT2) 106988167(PRDM2) 106989056(EHMT1)
BTA: 509382(SETDB2) 514062(EHMT2) 523047(SUV39H1) 528606(EHMT1) 536936(SUV39H2) 789222(PRDM2)
BOM: 102264756(SUV39H2) 102271111(EHMT1) 102271191(SUV39H1) 102279999(EHMT2) 102281203(PRDM2) 102287560(SETDB2)
BIU: 109565691(EHMT1) 109566720(SETDB2) 109567973(SUV39H2) 109570372(PRDM2) 109576929(EHMT2)
BBUB: 102392662(SETDB2) 102395323(EHMT1) 102396138(PRDM2) 102401546(SUV39H1) 102405188(EHMT2) 102415169(SUV39H2)
CHX: 102171636(PRDM2) 102174919(SUV39H1) 102176621(SUV39H2) 102178316(EHMT2) 102186776(SETDB2) 102189411(EHMT1)
OAS: 101110031(SUV39H1) 101115739(EHMT2) 101116064(SETDB2) 101116417(SUV39H2) 101123545(EHMT1) 105601941(PRDM2)
SSC: 100124382(EHMT2) 100157885(SETDB2) 100518559(PRDM2) 110258080(EHMT1) 664651(SUV39H2) 767626(SUV39H1)
CFR: 102514882(PRDM2) 102514903 102518579(EHMT2) 102521199(SUV39H2) 102521526(EHMT1)
CDK: 105087443(EHMT2) 105101932 105102102(EHMT1) 105103308(SUV39H1) 105104521(SUV39H2) 105107110(PRDM2)
BACU: 102999710(SUV39H2) 103005831(SUV39H1) 103017152(SETDB2) 103017744(EHMT1) 103018553(EHMT2) 103020862(PRDM2)
LVE: 103068757(SETDB2) 103072310(EHMT2) 103073919(SUV39H1) 103079038(EHMT1) 103083070(PRDM2) 103084616(SUV39H2)
OOR: 101269551(PRDM2) 101272833(EHMT1) 101279239(SUV39H2) 101282385(EHMT2) 101289196(SUV39H1)
DLE: 111169525(SUV39H1) 111170699(EHMT2) 111175303 111176964(EHMT1) 111178089(SUV39H2) 111187234(PRDM2)
PCAD: 102974835(PRDM2) 102978732(EHMT1) 102988226(SUV39H2) 102988363(SUV39H1) 102990347(SETDB2) 102993056(EHMT2)
ECB: 100054973(PRDM2) 100056120(SETDB2) 100058869(EHMT1) 100059118(EHMT2) 100062108(SUV39H1) 100068891(SUV39H2)
EPZ: 103544360 103544897(SUV39H1) 103554163(EHMT1) 103556824(SUV39H2) 103563300(EHMT2) 103563428(SETDB2) 103564688(PRDM2)
EAI: 106822324(EHMT2) 106822761(EHMT1) 106827436(SUV39H1) 106828015(PRDM2) 106829693(SETDB2) 106840452(SUV39H2)
MYB: 102243180(SUV39H1) 102245485(EHMT1) 102248401(SETDB2) 102249747(PRDM2) 102260054(SUV39H2) 102263672(EHMT2)
MYD: 102756540(EHMT1) 102757145(SUV39H2) 102760935(PRDM2) 102763954(SUV39H1) 102765299(SETDB2) 102773857(EHMT2)
MNA: 107531408(SETDB2) 107531564 107534821(SUV39H2) 107536199(EHMT1) 107538997(EHMT2) 107541392(SUV39H1)
HAI: 109373117(EHMT2) 109374812(SUV39H1) 109381271(PRDM2) 109382055(EHMT1) 109387125(SETDB2) 109393823(SUV39H2)
DRO: 112299124(PRDM2) 112302258(EHMT2) 112306260(EHMT1) 112313171 112320455(SUV39H2) 112322458(SUV39H1)
PALE: 102879374(EHMT2) 102879589(PRDM2) 102891996 102893102(EHMT1) 102894853(SUV39H1) 102898400(SUV39H2)
RAY: 107498490(EHMT2) 107503067(EHMT1) 107504834(SUV39H2) 107510017(SETDB2) 107513143(PRDM2) 107515026(SUV39H1)
MJV: 108397103(SUV39H2) 108397963(PRDM2) 108400840(EHMT2) 108403560(SETDB2) 108408400(SUV39H1)
LAV: 100653780(SUV39H1) 100658021(PRDM2) 100659207(EHMT2) 100670438 100674328(SUV39H2)
MDO: 100010516(PRDM2) 100014806(SUV39H2) 100018670(SUV39H1) 100023838(EHMT1) 100025360(EHMT2) 100028710(SETDB2)
SHR: 100922258(SUV39H1) 100931147(EHMT2) 100932927(EHMT1) 100933751(SUV39H2) 100934863 111719909(PRDM2)
PCW: 110198885(PRDM2) 110199440(EHMT2) 110201087(SUV39H1) 110205249(EHMT1) 110213411(SETDB2) 110217388(SUV39H2)
OAA: 100078328(EHMT1) 100082943(EHMT2) 100083315(SETDB2) 100084051(SUV39H1) 100085175(SUV39H2) 100681503(PRDM2)
GGA: 112529925 112529927(SUV39H1) 417250(EHMT1) 418866(SETDB2) 419478(PRDM2) 426314(SUV39H2)
CJO: 107307203(SUV39H1) 107308162 107319605(SUV39H2) 107321652(EHMT1) 107323354(PRDM2)
NMEL: 110391539(SUV39H1) 110392282(SUV39H2) 110406734(EHMT1) 110408674(PRDM2)
APLA: 101790074 101795723(PRDM2) 101796000(SUV39H2) 101805087(EHMT1)
ACYG: 106037080(EHMT1) 106040216(PRDM2) 106040219 106046190(SUV39H2)
TGU: 100217666(EHMT1) 100222565 100225827(SUV39H2) 100231131
LSR: 110469585 110470972(SUV39H2) 110476787(PRDM2) 110476956(EHMT1) 110481760(SUV39H1)
SCAN: 103813741(SUV39H2) 103819172(EHMT1) 103820835 103827401
GFR: 102031848(SUV39H2) 102036198(EHMT1) 106631968(PRDM2)
FAB: 101806838(EHMT1) 101812782(PRDM2) 101812936(PHF11) 101814584 101816158(SUV39H2)
PHI: 102099526(EHMT1) 102104074(SETDB2) 102110616(SUV39H1) 102111894(PRDM2) 102114300(SUV39H2)
PMAJ: 107204624(SUV39H2) 107211503 107212039(EHMT1) 107213672(PRDM2)
CCAE: 111923103(SUV39H2) 111935294 111936927(EHMT1) 111938730(PRDM2)
CCW: 104688230(EHMT1) 104689965 104693258(PRDM2) 104693366 104694491(SUV39H2)
ETL: 114065121(PRDM2) 114067139(EHMT1) 114067551(SUV39H2)
FPG: 101912815(SUV39H2) 101914490(PRDM2) 101916063(EHMT1) 101917763(SETDB2) 106112052
FCH: 102055395 102057247(EHMT1) 102059458(SUV39H2) 102059903 106631029(PRDM2)
CLV: 102085960(EHMT1) 102088543 102092575(PRDM2) 102098917(SUV39H2)
EGZ: 104124045(EHMT1) 104132393(SUV39H2) 104133098(PRDM2)
NNI: 104009017 104009090 104014630(SUV39H2) 104022219(EHMT1)
ACUN: 113486655(EHMT1) 113487883(PRDM2) 113489768(SUV39H2)
PADL: 103915032(SUV39H2) 103918059(PRDM2) 103918930(EHMT1)
AAM: 106482427(PRDM2) 106482431 106485143(SUV39H2) 106493032(EHMT1)
ASN: 102371718(PRDM2) 102374916(EHMT1) 102375358(SUV39H2) 102378805(SUV39H1) 102380189 102381770(EHMT2)
AMJ: 102558468(SUV39H1) 102561958(PRDM2) 102563656(SUV39H2) 102564850(EHMT1) 102574756(EHMT2) 102576351(SETDB2)
PSS: 102444308 102449381 102450225(EHMT1) 102450951 102454204(SUV39H2) 102462370(SUV39H1)
CMY: 102932781(SETDB2) 102933671(EHMT1) 102937045(SUV39H2) 102937831(SUV39H1) 102942942(PRDM2)
CPIC: 101939547(PRDM2) 101942163(EHMT1) 101945875(SUV39H2) 101947321(EHMT2) 101951503(SUV39H1)
ACS: 100552443(setdb2) 100553897(suv39h1) 100556375(ehmt2) 100565730(ehmt1) 100567365(prdm2)
PVT: 110072610 110081193(SUV39H1) 110088696(EHMT2) 110089799(EHMT1)
PBI: 103049261(EHMT2) 103052540(SUV39H1) 103053645 103057390(EHMT1) 103060604(PRDM2) 103067345
PMUR: 107291380(PRDM2) 107295037(EHMT2) 107300048(SUV39H1)
TSR: 106546114(SUV39H1) 106553032(PRDM2)
PMUA: 114588136(SUV39H1) 114589035(EHMT1) 114592073(EHMT2) 114593254(SETDB2) 114602405(PRDM2)
GJA: 107105480(EHMT2) 107106223(PRDM2) 107112843(SUV39H1) 107118801(EHMT1)
XLA: 100037174(suv39h2.L) 108696585(prdm2.L) 108698163(ehmt1.L) 108698559(ehmt2.L) 108699889(ehmt1.S) 108700299(suv39h1.S) 108713053(suv39h2.S) 398711(setdb2.S) 431943(suv39h1.L) 494709(prdm2.S)
XTR: 100124713(ehmt1) 100124743(setdb2) 100170624(prdm2) 100484992(ehmt2) 116408207 549262(suv39h2)
NPR: 108783946(PRDM2) 108786543(EHMT2) 108788266(SUV39H1) 108794066(SUV39H2) 108797823(SETDB2)
DRE: 100003615(prdm2a) 100005761(ehmt1a) 326906(suv39h1b) 335153(setdb2) 402830(ehmt1b) 445198(suv39h1a) 569250(ehmt2) 797296(prdm2b)
NCC: 104944159(ehmt1) 104951536(prdm2) 104953540(suv39h1) 104955184 104964983(ehmt2)
ONL: 100691163 100693758(suv39h1) 100697429(prdm2) 100697605(ehmt2) 100700166(ehmt1) 102080474 102081996(creg1)
XMA: 102218201(suv39h1) 102218386 102219854(ehmt1) 102225394 102225694(prdm2) 102232589(ehmt2)
CVG: 107083748(ehmt1) 107086188(ehmt2) 107088877 107089331(prdm2) 107090999(suv39h1) 107099179
KMR: 108228258(setdb2) 108231376(prdm2b) 108231967 108236789(prdm2a) 108243867(ehmt2) 108249279(ehmt1b) 108251110(ehmt1a)
CSEM: 103384853(suv39h1) 103384937 103385671(prdm2) 103389803(setdb2) 103394057(ehmt2) 103397363
BPEC: 110154648(ehmt1) 110156027(suv39h1) 110158800 110166512 110168576(prdm2) 110173288(ehmt2)
SFM: 108918498(prdm2) 108922673(ehmt1) 108924930 108934780(suv39h1) 108935584(ehmt2) 108937739
LCM: 102351913 102359250(PRDM2) 102360554(SUV39H2) 102361297(EHMT1) 102363588(SETDB2)
CMK: 103173106 103180404(ehmt1) 103181338(prdm2)
RTP: 109911717(setdb2) 109919887(ehmt2) 109921345(suv39h2) 109926709(ehmt1) 109937263(prdm2)
CIN: 100186548
DME: Dmel_CG2995(G9a) Dmel_CG43664(Su(var)3-9)
DER: 6555648
DSE: 6615843
DSI: Dsimw501_GD16494(Dsim_GD16494)
DSR: 110180428
DVI: 6633588
AAG: 5573963
AME: 413388
BIM: 100740627
CCAL: 108623497
ACEP: 105619940
HAW: 110370326
TNL: 113498295
PVM: 113827542
CSCU: 111614908
BMY: Bm1_19060
TSP: Tsp_05330
SHX: MS3_09983
EPA: 110242114
ADF: 107356587
AMIL: 114953395
PDAM: 113686615
SPIS: 111341162
DGT: 114521829
ATH: AT2G22740(SUVH6) AT2G33290(SUVH2) AT2G35160(SUVH5) AT4G13460(SUVH9) AT5G13960(SUVH4)
LJA: Lj1g3v3904410.1(Lj1g3v3904410.1) Lj2g3v1989010.1(Lj2g3v1989010.1)
DOSA: Os01t0927000-01(Os01g0927000) Os07t0435900-01(Os07g0435900) Os08t0565700-01(Os08g0565700) Os09t0362900-01(Os09g0362900)
ATS: 109741537(LOC109741537) 109769961(LOC109769961) 109770115 109774279(LOC109774279)
OLU: OSTLU_25709(SDG3507)
NCR: NCU04402(dim-5)
NTE: NEUTE1DRAFT121214(NEUTE1DRAFT_121214)
MGR: MGG_06852
SSCK: SPSK_07647
NHE: NECHADRAFT_94199(SDG2104)
MAW: MAC_09094
MAJ: MAA_00272
CMT: CCM_00746
BFU: BCIN_11g02360(BcDIM5)
MBE: MBM_05751
ANI: AN1170.2
ANG: ANI_1_1828074(An08g03380)
ABE: ARB_02816
TVE: TRV_01916
PTE: PTT_11395
ZTR: MYCGRDRAFT_107709(SDG2411)
SPO: SPBC428.08c(clr4)
CNE: CNH00720
CNB: CNBL0680
TASA: A1Q1_02905
LBC: LACBIDRAFT_296206(SDG16210) LACBIDRAFT_300409(SDG16205)
ABP: AGABI1DRAFT108076(AGABI1DRAFT_108076) AGABI1DRAFT129982(AGABI1DRAFT_129982)
ABV: AGABI2DRAFT146074(AGABI2DRAFT_146074) AGABI2DRAFT180791(AGABI2DRAFT_180791)
 » show all
Reference
1  [PMID:11094092]
  Authors
O'Carroll D, Scherthan H, Peters AH, Opravil S, Haynes AR, Laible G, Rea S, Schmid M, Lebersorger A, Jerratsch M, Sattler L, Mattei MG, Denny P, Brown SD, Schweizer D, Jenuwein T
  Title
Isolation and characterization of Suv39h2, a second histone H3 methyltransferase  gene that displays testis-specific expression.
  Journal
Mol Cell Biol 20:9423-33 (2000)
DOI:10.1128/mcb.20.24.9423-9433.2000
  Sequence
[mmu:20937 64707]
Reference
2  [PMID:11867540]
  Authors
Schotta G, Ebert A, Krauss V, Fischer A, Hoffmann J, Rea S, Jenuwein T, Dorn R, Reuter G
  Title
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.
  Journal
EMBO J 21:1121-31 (2002)
DOI:10.1093/emboj/21.5.1121
  Sequence
Reference
3  [PMID:12130538]
  Authors
Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M, Fukuda M, Takeda N, Niida H, Kato H, Shinkai Y
  Title
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.
  Journal
Genes Dev 16:1779-91 (2002)
DOI:10.1101/gad.989402
  Sequence
[mmu:110147]
Reference
4  [PMID:11959841]
  Authors
Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ 3rd
  Title
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase  that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins.
  Journal
Genes Dev 16:919-32 (2002)
DOI:10.1101/gad.973302
  Sequence
[hsa:9869]
Reference
5  [PMID:14633678]
  Authors
Kim KC, Geng L, Huang S
  Title
Inactivation of a histone methyltransferase by mutations in human cancers.
  Journal
Cancer Res 63:7619-23 (2003)
  Sequence
[hsa:7799]
Reference
6  [PMID:20084102]
  Authors
Wu H, Min J, Lunin VV, Antoshenko T, Dombrovski L, Zeng H, Allali-Hassani A, Campagna-Slater V, Vedadi M, Arrowsmith CH, Plotnikov AN, Schapira M
  Title
Structural biology of human H3K9 methyltransferases.
  Journal
PLoS One 5:e8570 (2010)
DOI:10.1371/journal.pone.0008570
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.355
IUBMB Enzyme Nomenclature: 2.1.1.355
ExPASy - ENZYME nomenclature database: 2.1.1.355
BRENDA, the Enzyme Database: 2.1.1.355
LinkDB

DBGET integrated database retrieval system