| Entry |
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| Name |
acetylornithine transaminase;
acetylornithine delta-transaminase;
ACOAT;
acetylornithine 5-aminotransferase;
acetylornithine aminotransferase;
N-acetylornithine aminotransferase;
N-acetylornithine-delta-transaminase;
N2-acetylornithine 5-transaminase;
N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase;
succinylornithine aminotransferase;
2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase
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| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
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| Sysname |
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase
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| Reaction(IUBMB) |
N2-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate [RN: R02283]
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| Reaction(KEGG) |
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| Substrate |
N2-acetyl-L-ornithine [CPD: C00437];
2-oxoglutarate [CPD: C00026]
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| Product |
N-acetyl-L-glutamate 5-semialdehyde [CPD: C01250];
L-glutamate [CPD: C00025]
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| Comment |
A pyridoxal-phosphate protein. Also acts on L-ornithine and N2-succinyl-L-ornithine.
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| History |
EC 2.6.1.11 created 1961, modified 2004 (EC 2.6.1.69 created 1989, incorporated 2004)
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| Pathway |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K00818 | acetylornithine aminotransferase |
| K00821 | acetylornithine/N-succinyldiaminopimelate aminotransferase |
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| Genes |
» show all
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| Reference |
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| Authors |
ALBRECHT AM, VOGEL HJ. |
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| Title |
ACETYLORNITHINE DELTA-TRANSAMINASE. PARTIAL PURIFICATION AND REPRESSION BEHAVIOR. |
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| Journal |
J Biol Chem 239:1872-6 (1964) |
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| Reference |
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| Authors |
Vogel HJ. |
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| Title |
Path of Ornithine Synthesis in Escherichia Coli. |
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| Journal |
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| Reference |
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| Authors |
Vander Wauven C, Stalon V. |
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| Title |
Occurrence of succinyl derivatives in the catabolism of arginine in Pseudomonas cepacia. |
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| Journal |
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| Reference |
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| Authors |
Voellmy R, Leisinger T. |
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| Title |
Dual role for N-2-acetylornithine 5-aminotransferase from Pseudomonas aeruginosa in arginine biosynthesis and arginine catabolism. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.6.1.11 |
| ExPASy - ENZYME nomenclature database: | 2.6.1.11 |
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| LinkDB |
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