KEGG   COMPOUND: C00026Help
Entry
C00026                      Compound                               

Name
2-Oxoglutarate;
Oxoglutaric acid;
2-Ketoglutaric acid;
alpha-Ketoglutaric acid
Formula
C5H6O5
Exact mass
146.0215
Mol weight
146.0981
Structure
Mol fileKCF fileDB search
Reaction
R00021 R00093 R00114 R00243 R00248 R00250 R00258 R00264
R00265 R00267 R00268 R00269 R00270 R00271 R00272 R00279
R00298 R00355 R00372 R00457 R00474 R00563 R00621 R00667
R00668 R00684 R00694 R00709 R00715 R00716 R00734 R00895
R00896 R00908 R01090 R01148 R01155 R01161 R01197 R01214
R01252 R01339 R01412 R01580 R01582 R01587 R01648 R01684
R01700 R01879 R01939 R01956 R02077 R02160 R02199 R02274
R02283 R02397 R02433 R02444 R02445 R02486 R02619 R02700
R02772 R02773 R03008 R03009 R03053 R03063 R03120 R03126
R03207 R03218 R03219 R03225 R03243 R03248 R03266 R03376
 » show all
Pathway
map00020  Citrate cycle (TCA cycle)
map00040  Pentose and glucuronate interconversions
map00053  Ascorbate and aldarate metabolism
map00220  Arginine biosynthesis
map00250  Alanine, aspartate and glutamate metabolism
map00300  Lysine biosynthesis
map00340  Histidine metabolism
map00365  Furfural degradation
map00430  Taurine and hypotaurine metabolism
map00471  D-Glutamine and D-glutamate metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map00650  Butanoate metabolism
map00660  C5-Branched dibasic acid metabolism
map00720  Carbon fixation pathways in prokaryotes
map01060  Biosynthesis of plant secondary metabolites
map01061  Biosynthesis of phenylpropanoids
map01062  Biosynthesis of terpenoids and steroids
map01063  Biosynthesis of alkaloids derived from shikimate pathway
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01065  Biosynthesis of alkaloids derived from histidine and purine
map01066  Biosynthesis of alkaloids derived from terpenoid and polyketide
map01070  Biosynthesis of plant hormones
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01130  Biosynthesis of antibiotics
map01200  Carbon metabolism
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map04066  HIF-1 signaling pathway
map04727  GABAergic synapse
map04922  Glucagon signaling pathway
map04964  Proximal tubule bicarbonate reclamation
map04976  Bile secretion
map05230  Central carbon metabolism in cancer
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00173  Reductive citrate cycle (Arnon-Buchanan cycle)
M00433  Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
M00532  Photorespiration
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
M00620  Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate
M00740  Methylaspartate cycle
Enzyme
1.1.1.41        1.1.1.42        1.1.1.95        1.1.1.286       
1.1.1.399       1.1.99.2        1.1.99.24       1.1.99.39       
1.1.99.40       1.2.1.3         1.2.1.26        1.2.1.52        
1.2.1.-         1.2.4.2         1.2.7.3         1.2.7.11        
1.4.1.2         1.4.1.3         1.4.1.4         1.4.1.13        
1.4.1.14        1.4.3.7         1.4.3.11        1.4.3.15        
1.4.7.1         1.5.1.7         1.5.1.8         1.5.1.19        
1.5.1.51        1.8.1.4         1.13.12.19      1.14.11.1       
1.14.11.2       1.14.11.3       1.14.11.4       1.14.11.6       
1.14.11.7       1.14.11.8       1.14.11.9       1.14.11.10      
1.14.11.11      1.14.11.12      1.14.11.13      1.14.11.14      
1.14.11.15      1.14.11.16      1.14.11.17      1.14.11.18      
1.14.11.20      1.14.11.21      1.14.11.24      1.14.11.25      
1.14.11.26      1.14.11.27      1.14.11.28      1.14.11.31      
1.14.11.32      1.14.11.35      1.14.11.36      1.14.11.37      
1.14.11.38      1.14.11.39      1.14.11.40      1.14.11.41      
1.14.11.42      1.14.11.43      1.14.11.44      1.14.11.45      
1.14.11.46      1.14.11.48      1.14.11.49      1.14.11.51      
1.14.11.52      1.14.11.55      1.14.11.56      1.14.11.57      
1.14.11.58      1.14.11.59      1.14.11.-       1.14.20.1       
1.14.20.3       1.14.20.4       1.14.20.5       1.14.20.6       
1.14.20.7       1.14.20.8       1.14.20.-       2.2.1.5         
2.2.1.9         2.3.1.61        2.3.3.4         2.3.3.14        
2.6.1.1         2.6.1.2         2.6.1.3         2.6.1.4         
2.6.1.5         2.6.1.6         2.6.1.7         2.6.1.8         
2.6.1.9         2.6.1.11        2.6.1.13        2.6.1.17        
2.6.1.19        2.6.1.21        2.6.1.22        2.6.1.23        
2.6.1.24        2.6.1.26        2.6.1.27        2.6.1.29        
2.6.1.33        2.6.1.34        2.6.1.36        2.6.1.38        
2.6.1.39        2.6.1.40        2.6.1.42        2.6.1.44        
2.6.1.48        2.6.1.49        2.6.1.52        2.6.1.54        
2.6.1.55        2.6.1.57        2.6.1.59        2.6.1.65        
2.6.1.67        2.6.1.72        2.6.1.74        2.6.1.75        
2.6.1.76        2.6.1.79        2.6.1.80        2.6.1.81        
2.6.1.82        2.6.1.83        2.6.1.87        2.6.1.89        
2.6.1.90        2.6.1.92        2.6.1.93        2.6.1.94        
2.6.1.95        2.6.1.98        2.6.1.102       2.6.1.103       
2.6.1.104       2.6.1.106       2.6.1.107       2.6.1.109       
2.6.1.110       2.6.1.111       2.6.1.114       2.6.1.-         
3.5.1.3         3.5.1.36        3.5.1.111       3.5.1.128       
4.1.1.71        4.2.1.168       6.4.1.7
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Organic acids
  Carboxylic acids
   2-Oxocarboxylic acids
    C00026  2-Oxoglutarate
BRITE hierarchy
Other DBs
CAS: 328-50-7
PubChem: 3328
ChEBI: 16810 30915
ChEMBL: CHEMBL1686
KNApSAcK: C00000769
PDB-CCD: AKG[PDBj]
3DMET: B00008
NIKKAJI: J11.847H
LinkDB All DBs
KCF data Show

ATOM        10
            1   C5a C    27.7045  -20.9076
            2   C1b C    26.4954  -20.2102
            3   C6a C    28.9072  -20.2102
            4   O5a O    27.7045  -22.3718
            5   C1b C    25.2927  -20.9076
            6   O6a O    30.1100  -20.9139
            7   O6a O    28.9007  -18.8219
            8   C6a C    24.0836  -20.2102
            9   O6a O    24.0899  -18.8219
            10  O6a O    22.8808  -20.9139
BOND        9
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     8   9 2
            9     8  10 1

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