| Entry |
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| Name |
phosphomevalonate kinase;
ATP:5-phosphomevalonate phosphotransferase;
5-phosphomevalonate kinase;
mevalonate phosphate kinase;
mevalonate-5-phosphate kinase;
mevalonic acid phosphate kinase
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
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| Sysname |
ATP:(R)-5-phosphomevalonate phosphotransferase
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| Reaction(IUBMB) |
ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate [RN: R03245]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| History |
EC 2.7.4.2 created 1961
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| Pathway |
| ec00900 | Terpenoid backbone biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K00938 | phosphomevalonate kinase |
| K13273 | phosphomevalonate kinase |
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| Genes |
» show all
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| Reference |
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| Authors |
BLOCH K, CHAYKIN S, PHILLIPS AH, DE WAARD A. |
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| Title |
Mevalonic acid pyrophosphate and isopentenylpyrophosphate. |
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| Journal |
J Biol Chem 234:2595-604 (1959) |
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| Reference |
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| Authors |
HENNING U, MOSLEIN EM, LYNEN F. |
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| Title |
Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase. |
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| Journal |
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| Reference |
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| Authors |
LEVY HR, POPJAK G. |
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| Title |
Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.4.2 |
| ExPASy - ENZYME nomenclature database: | 2.7.4.2 |
| BRENDA, the Enzyme Database: | 2.7.4.2 |
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| LinkDB |
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