Entry |
|
Name |
(2R)-sulfolactate sulfo-lyase;
Suy;
SuyAB;
3-sulfolactate bisulfite-lyase;
sulfolactate sulfo-lyase (ambigious);
(2R)-3-sulfolactate bisulfite-lyase (pyruvate-forming)
|
Class |
Lyases;
Carbon-sulfur lyases;
Carbon-sulfur lyases (only sub-subclass identified to date)
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Sysname |
(2R)-3-sulfolactate hydrogensulfite-lyase (pyruvate-forming)
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Reaction(IUBMB) |
(2R)-3-sulfolactate = pyruvate + hydrogensulfite [RN: R07633]
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Reaction(KEGG) |
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Substrate |
(2R)-3-sulfolactate [CPD: C11537]
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Product |
pyruvate [CPD: C00022];
hydrogensulfite
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Comment |
Requires iron(II). This inducible enzyme participates in cysteate degradation by the bacterium Paracoccus pantotrophus NKNCYSA and in 3-sulfolactate degradation by the bacterium Chromohalobacter salexigens. The enzyme is specific for the (R) isomer of its substrate.
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History |
EC 4.4.1.24 created 2006, modified 2011
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Pathway |
ec00270 | Cysteine and methionine metabolism |
|
Orthology |
K16845 | (2R)-sulfolactate sulfo-lyase subunit alpha |
K16846 | (2R)-sulfolactate sulfo-lyase subunit beta |
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Genes |
» show all
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Reference |
|
Authors |
Graham DE, White RH. |
Title |
Elucidation of methanogenic coenzyme biosyntheses: from spectroscopy to genomics. |
Journal |
|
Reference |
|
Authors |
Rein U, Gueta R, Denger K, Ruff J, Hollemeyer K, Cook AM |
Title |
Dissimilation of cysteate via 3-sulfolactate sulfo-lyase and a sulfate exporter in Paracoccus pantotrophus NKNCYSA. |
Journal |
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Sequence |
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Reference |
|
Authors |
Denger K, Cook AM |
Title |
Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase. |
Journal |
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Sequence |
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Other DBs |
ExplorEnz - The Enzyme Database: | 4.4.1.24 |
ExPASy - ENZYME nomenclature database: | 4.4.1.24 |
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LinkDB |
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