KEGG   COMPOUND: C00022
Entry
C00022                      Compound                               
Name
Pyruvate;
Pyruvic acid;
2-Oxopropanoate;
2-Oxopropanoic acid;
Pyroracemic acid
Formula
C3H4O3
Exact mass
88.016
Mol weight
88.0621
Structure
Reaction
Pathway
map00010  Glycolysis / Gluconeogenesis
map00020  Citrate cycle (TCA cycle)
map00030  Pentose phosphate pathway
map00040  Pentose and glucuronate interconversions
map00053  Ascorbate and aldarate metabolism
map00250  Alanine, aspartate and glutamate metabolism
map00260  Glycine, serine and threonine metabolism
map00261  Monobactam biosynthesis
map00270  Cysteine and methionine metabolism
map00290  Valine, leucine and isoleucine biosynthesis
map00330  Arginine and proline metabolism
map00350  Tyrosine metabolism
map00360  Phenylalanine metabolism
map00362  Benzoate degradation
map00430  Taurine and hypotaurine metabolism
map00440  Phosphonate and phosphinate metabolism
map00470  D-Amino acid metabolism
map00620  Pyruvate metabolism
map00621  Dioxin degradation
map00622  Xylene degradation
map00630  Glyoxylate and dicarboxylate metabolism
map00650  Butanoate metabolism
map00660  C5-Branched dibasic acid metabolism
map00680  Methane metabolism
map00710  Carbon fixation in photosynthetic organisms
map00720  Carbon fixation pathways in prokaryotes
map00730  Thiamine metabolism
map00760  Nicotinate and nicotinamide metabolism
map00770  Pantothenate and CoA biosynthesis
map00900  Terpenoid backbone biosynthesis
map00997  Biosynthesis of various other secondary metabolites
map00998  Biosynthesis of various antibiotics
map01060  Biosynthesis of plant secondary metabolites
map01061  Biosynthesis of phenylpropanoids
map01062  Biosynthesis of terpenoids and steroids
map01063  Biosynthesis of alkaloids derived from shikimate pathway
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01065  Biosynthesis of alkaloids derived from histidine and purine
map01066  Biosynthesis of alkaloids derived from terpenoid and polyketide
map01070  Biosynthesis of plant hormones
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01210  2-Oxocarboxylic acid metabolism
map01220  Degradation of aromatic compounds
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map01502  Vancomycin resistance
map02060  Phosphotransferase system (PTS)
map04066  HIF-1 signaling pathway
map04152  AMPK signaling pathway
map04911  Insulin secretion
map04922  Glucagon signaling pathway
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map05230  Central carbon metabolism in cancer
map05415  Diabetic cardiomyopathy
Module
M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002  Glycolysis, core module involving three-carbon compounds
M00008  Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00061  D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P
M00096  C5 isoprenoid biosynthesis, non-mevalonate pathway
M00169  CAM (Crassulacean acid metabolism), light
M00171  C4-dicarboxylic acid cycle, NAD - malic enzyme type
M00172  C4-dicarboxylic acid cycle, NADP - malic enzyme type
M00173  Reductive citrate cycle (Arnon-Buchanan cycle)
M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
M00308  Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P
M00309  Non-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate
M00374  Dicarboxylate-hydroxybutyrate cycle
M00376  3-Hydroxypropionate bi-cycle
M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
M00620  Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate
M00631  D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P
M00633  Semi-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate-3P
Enzyme
1.1.1.27        1.1.1.28        1.1.1.38        1.1.1.39        
1.1.1.40        1.1.1.83        1.1.2.3         1.1.2.4         
1.1.2.5         1.1.3.2         1.1.5.12        1.1.99.6        
1.1.99.7        1.1.99.40       1.2.1.22        1.2.1.23        
1.2.1.49        1.2.1.51        1.2.1.104       1.2.3.3         
1.2.3.6         1.2.3.15        1.2.4.1         1.2.5.1         
1.2.7.1         1.2.7.11        1.2.7.-         1.3.1.110       
1.4.1.1         1.4.1.17        1.4.3.3         1.4.3.19        
1.5.1.11        1.5.1.16        1.5.1.17        1.5.1.22        
1.5.1.23        1.5.1.24        1.5.1.26        1.5.1.28        
1.5.1.52        1.14.11.43      1.14.11.44      2.1.3.1         
2.2.1.6         2.2.1.7         2.2.1.12        2.3.1.54        
2.3.3.21        2.6.1.2         2.6.1.12        2.6.1.15        
2.6.1.18        2.6.1.21        2.6.1.30        2.6.1.37        
2.6.1.40        2.6.1.41        2.6.1.43        2.6.1.44        
2.6.1.46        2.6.1.47        2.6.1.51        2.6.1.56        
2.6.1.58        2.6.1.66        2.6.1.71        2.6.1.77        
2.6.1.84        2.6.1.96        2.6.1.99        2.6.1.108       
2.6.1.113       2.6.1.115       2.6.1.119       2.6.3.1         
2.7.1.40        2.7.1.121       2.7.3.9         2.7.9.1         
2.7.9.2         2.8.1.2         3.1.3.60        3.3.2.1         
3.3.2.13        3.3.2.15        3.5.99.10       3.7.1.5         
3.7.1.6         3.7.1.20        3.7.1.23        3.7.1.26        
3.7.1.-         3.11.1.3        4.1.1.1         4.1.1.64        
4.1.1.78        4.1.1.112       4.1.1.-         4.1.2.14        
4.1.2.18        4.1.2.20        4.1.2.21        4.1.2.23        
4.1.2.28        4.1.2.34        4.1.2.45        4.1.2.51        
4.1.2.52        4.1.2.53        4.1.2.54        4.1.2.55        
4.1.2.58        4.1.2.-         4.1.3.3         4.1.3.16        
4.1.3.17        4.1.3.22        4.1.3.25        4.1.3.27        
4.1.3.30        4.1.3.32        4.1.3.38        4.1.3.39        
4.1.3.40        4.1.3.42        4.1.3.43        4.1.3.44        
4.1.3.45        4.1.3.46        4.1.99.1        4.1.99.2        
4.2.1.-         4.2.99.20       4.2.99.21       4.3.1.10        
4.3.1.13        4.3.1.15        4.3.1.17        4.3.1.18        
4.3.1.19        4.3.3.7         4.4.1.1         4.4.1.13        
4.4.1.15        4.4.1.24        4.4.1.25        4.4.1.28        
4.4.1.35        4.4.1.36        4.4.1.-         4.5.1.2         
6.4.1.1         7.2.4.2
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Organic acids
  Carboxylic acids
   2-Oxocarboxylic acids
    C00022  Pyruvate; 2-Oxopropanoate
Lipids [BR:br08002]
 FA  Fatty acyls
  FA01 Fatty Acids and Conjugates
   FA0106 Oxo fatty acids
    C00022  2-Oxopropanoic acid
Other DBs
CAS: 127-17-3
PubChem: 3324
ChEBI: 15361 32816
LIPIDMAPS: LMFA01060077
LipidBank: DFA0385
KNApSAcK: C00001200
PDB-CCD: PYR[PDBj]
3DMET: B00006
NIKKAJI: J2.015J
LinkDB
KCF data

ATOM        6
            1   C1a C    12.6924  -17.4300
            2   C5a C    13.9049  -16.7300
            3   C6a C    15.1173  -17.4300
            4   O6a O    16.3318  -16.7288
            5   O5a O    13.9049  -15.3302
            6   O6a O    15.1173  -18.8300
BOND        5
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     2   5 2
            5     3   6 2

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