Entry |
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Name |
biotin---[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase;
biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] synthetase;
biotin-propionyl coenzyme A carboxylase synthetase;
propionyl coenzyme A holocarboxylase synthetase
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Class |
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
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Sysname |
biotin:apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming)
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Reaction(IUBMB) |
ATP + biotin + apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [propionyl-CoA:carbon-dioxide ligase (ADP-forming)] [RN: R04582]
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Reaction(KEGG) |
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Substrate |
ATP [CPD: C00002];
biotin [CPD: C00120];
apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD: C04763]
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Product |
AMP [CPD: C00020];
diphosphate [CPD: C00013];
[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD: C04727]
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History |
EC 6.3.4.10 created 1972
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Pathway |
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Orthology |
K01942 | biotin---protein ligase |
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Genes |
» show all
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Reference |
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Authors |
SIEGEL L, FOOTE JL, COON MJ. |
Title |
THE ENZYMATIC SYNTHESIS OF PROPIONYL COENZYME A HOLOCARBOXYLASE FROM D-BIOTINYL 5'-ADENYLATE AND THE APOCARBOXYLASE. |
Journal |
J Biol Chem 240:1025-31 (1965) |
Other DBs |
ExplorEnz - The Enzyme Database: | 6.3.4.10 |
ExPASy - ENZYME nomenclature database: | 6.3.4.10 |
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LinkDB |
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