Enhydra lutris kenyoni (northern sea otter): 111139613 Help Entry 111139613         CDS       T05871                                  Definition (RefSeq) protein kinase C gamma type   KO K19663   classical protein kinase C gamma type [EC:2.7.11.13] Organism elk  Enhydra lutris kenyoni (northern sea otter) Pathway elk01521   EGFR tyrosine kinase inhibitor resistance elk04010   MAPK signaling pathway elk04012   ErbB signaling pathway elk04014   Ras signaling pathway elk04015   Rap1 signaling pathway elk04020   Calcium signaling pathway elk04066   HIF-1 signaling pathway elk04070   Phosphatidylinositol signaling system elk04071   Sphingolipid signaling pathway elk04150   mTOR signaling pathway elk04270   Vascular smooth muscle contraction elk04310   Wnt signaling pathway elk04370   VEGF signaling pathway elk04510   Focal adhesion elk04540   Gap junction elk04650   Natural killer cell mediated cytotoxicity elk04666   Fc gamma R-mediated phagocytosis elk04670   Leukocyte transendothelial migration elk04713   Circadian entrainment elk04720   Long-term potentiation elk04723   Retrograde endocannabinoid signaling elk04724   Glutamatergic synapse elk04725   Cholinergic synapse elk04726   Serotonergic synapse elk04727   GABAergic synapse elk04728   Dopaminergic synapse elk04730   Long-term depression elk04750   Inflammatory mediator regulation of TRP channels elk04911   Insulin secretion elk04916   Melanogenesis elk04918   Thyroid hormone synthesis elk04919   Thyroid hormone signaling pathway elk04921   Oxytocin signaling pathway elk04925   Aldosterone synthesis and secretion elk04928   Parathyroid hormone synthesis, secretion and action elk04929   GnRH secretion elk04935   Growth hormone synthesis, secretion and action elk04960   Aldosterone-regulated sodium reabsorption elk04961   Endocrine and other factor-regulated calcium reabsorption elk04970   Salivary secretion elk04971   Gastric acid secretion elk04972   Pancreatic secretion elk05017   Spinocerebellar ataxia elk05022   Pathways of neurodegeneration - multiple diseases elk05031   Amphetamine addiction elk05032   Morphine addiction elk05143   African trypanosomiasis elk05146   Amoebiasis elk05161   Hepatitis B elk05163   Human cytomegalovirus infection elk05170   Human immunodeficiency virus 1 infection elk05171   Coronavirus disease - COVID-19 elk05200   Pathways in cancer elk05205   Proteoglycans in cancer elk05206   MicroRNAs in cancer elk05214   Glioma elk05223   Non-small cell lung cancer elk05225   Hepatocellular carcinoma elk05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:elk00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     111139613    04012 ErbB signaling pathway     111139613    04014 Ras signaling pathway     111139613    04015 Rap1 signaling pathway     111139613    04310 Wnt signaling pathway     111139613    04370 VEGF signaling pathway     111139613    04066 HIF-1 signaling pathway     111139613    04020 Calcium signaling pathway     111139613    04070 Phosphatidylinositol signaling system     111139613    04071 Sphingolipid signaling pathway     111139613    04150 mTOR signaling pathway     111139613  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     111139613    04540 Gap junction     111139613  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     111139613    04666 Fc gamma R-mediated phagocytosis     111139613    04670 Leukocyte transendothelial migration     111139613   09152 Endocrine system    04911 Insulin secretion     111139613    04929 GnRH secretion     111139613    04921 Oxytocin signaling pathway     111139613    04935 Growth hormone synthesis, secretion and action     111139613    04918 Thyroid hormone synthesis     111139613    04919 Thyroid hormone signaling pathway     111139613    04928 Parathyroid hormone synthesis, secretion and action     111139613    04916 Melanogenesis     111139613    04925 Aldosterone synthesis and secretion     111139613   09153 Circulatory system    04270 Vascular smooth muscle contraction     111139613   09154 Digestive system    04970 Salivary secretion     111139613    04971 Gastric acid secretion     111139613    04972 Pancreatic secretion     111139613   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     111139613    04961 Endocrine and other factor-regulated calcium reabsorption     111139613   09156 Nervous system    04724 Glutamatergic synapse     111139613    04727 GABAergic synapse     111139613    04725 Cholinergic synapse     111139613    04728 Dopaminergic synapse     111139613    04726 Serotonergic synapse     111139613    04720 Long-term potentiation     111139613    04730 Long-term depression     111139613    04723 Retrograde endocannabinoid signaling     111139613   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     111139613   09159 Environmental adaptation    04713 Circadian entrainment     111139613  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111139613    05206 MicroRNAs in cancer     111139613    05205 Proteoglycans in cancer     111139613    05231 Choline metabolism in cancer     111139613   09162 Cancer: specific types    05225 Hepatocellular carcinoma     111139613    05214 Glioma     111139613    05223 Non-small cell lung cancer     111139613   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     111139613    05022 Pathways of neurodegeneration - multiple diseases     111139613   09165 Substance dependence    05031 Amphetamine addiction     111139613    05032 Morphine addiction     111139613   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     111139613    05161 Hepatitis B     111139613    05171 Coronavirus disease - COVID-19     111139613    05163 Human cytomegalovirus infection     111139613   09174 Infectious disease: parasitic    05146 Amoebiasis     111139613    05143 African trypanosomiasis     111139613   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     111139613  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:elk01001]     111139613 Enzymes [BR:elk01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      111139613 Protein kinases [BR:elk01001]  Serine/threonine kinases: AGC group   PKC family [OT]    111139613 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C Kinase-like Motif Other DBs NCBI-GeneID:  111139613 NCBI-ProteinID:  XP_022347647 UniProt:  A0A2Y9IG42 LinkDB All DBs Position Unknown AA seq 697 aa AA seqDB search MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHVTVGEA RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDSKRCFFGTSPGRLHISDFSFLMVLGKG SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD LKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPAKRLGS GPDGEPAIRAHGFFRWMDWERLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL VLASIDQADFQGFTYVNPDFVHPDARSPVSPPPVPVM NT seq 2094 nt NT seq  +upstreamnt  +downstreamnt atggcaggcctgggccccggcggaggcgattcagaggggggaccccggcccctgttttgc agaaagggggctctgaggcagaaggtggtccacgaagtcaagagccacaagttcaccgcc cgcttcttcaagcagccaaccttctgcagccactgcaccgacttcatctgggggattgga aaacagggcctgcaatgtcaagtctgcagctttgtggttcatcgacgatgccacgaattt gtgaccttcgagtgtccaggcgctgggaagggcccccagacggatgacccccgaaacaag cacaagttccgtctgcacagctacagcagccccaccttctgtgaccactgcggctccctt ctctacgggctggtgcaccagggcatgaaatgctcctgctgcgagatgaacgtgcaccgg cgctgtgtgcgcagcgtgccctctctgtgcggggtggaccacacggagcgccgtgggcgg ctgcagctagagatccgagcaccgacggcagatgagatccacgtcacagttggtgaggcc cgtaatctcatcccaatggatcccaatggtctgtcggatccctatgtgaagctgaagctt atcccagaccctcggaacttgacaaaacagaagacccggacggtgaaagccacactaaac cctgtgtggaacgagacctttgtgttcaacctgaagccaggggacgtggagcgccggctc agcgtggaggtgtgggactgggaccggacttcccgcaacgacttcatgggtgccatgtcc ttcggggtctcagagctgctcaaggccccggtggatggctggtacaagttactgaaccag gaggagggcgaatattacaatgtgccggtggctgacgctgacaactgcagcctcctccag aagtttgaggcctgtaactaccccctggaactctatgagcgcgtgcggatgggtccctct tcttctcccatcccttccccatcccccagtcccaccgactccaagcgctgtttctttggg acgagccccggacgtctccacatctctgacttcagcttcctcatggttctaggaaaaggc agttttgggaaggtgatgctggctgagcgcaggggctccgatgagctctatgccatcaag atcttgaagaaagacgtgattgtccaggacgacgacgtggactgcaccctcgtggagaag cgagtgctggccctggggggccgaggcccggggggccggccccactttctcacccagctg cactccaccttccagaccccggatcgcctgtatttcgtgatggagtatgtcaccgggggc gacttgatgtaccacattcagcagctgggcaagtttaaggagccccatgccgcgttctac gcagcggaaatcgccatcggcctcttcttccttcacaatcagggcatcatctaccgggac ctgaaactagacaacgtcatgctggatgccgaaggacacatcaaaatcactgacttcggc atgtgtaaggagaacgtcttcccggggaccacgacccgcaccttctgtgggaccccagac tacatagcccctgagatcattgcctaccagccctatgggaagtctgtggattggtggtcc tttggggttctgctgtatgagatgctggcaggacagcccccttttgatggggaggatgag gaagagctgtttcaggccatcatggaacaaactgtcacttaccccaagtcgctttcccga gaagccgtggcgatctgcaaggggttcctaactaagcacccagcgaaacgcctgggctca gggcccgacggggagcccgccatccgtgctcatggctttttccgctggatggactgggag cgcctggaacggctggagatagcgcctcctttcagaccccgtccgtgtggacgcagcggc gagaacttcgacaaattcttcacgcgggcggcgcccgcgctgaccccgccggaccgccta gttttggccagcatcgaccaggccgacttccaaggcttcacctacgtgaacccggatttc gtgcaccccgacgcccgcagccccgtcagcccaccgcctgtgccagtcatgtaa

Enhydra lutris kenyoni (northern sea otter): 111158087 Help Entry 111158087         CDS       T05871                                  Definition (RefSeq) protein kinase C alpha type isoform X1   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism elk  Enhydra lutris kenyoni (northern sea otter) Pathway elk01521   EGFR tyrosine kinase inhibitor resistance elk04010   MAPK signaling pathway elk04012   ErbB signaling pathway elk04014   Ras signaling pathway elk04015   Rap1 signaling pathway elk04020   Calcium signaling pathway elk04066   HIF-1 signaling pathway elk04070   Phosphatidylinositol signaling system elk04071   Sphingolipid signaling pathway elk04072   Phospholipase D signaling pathway elk04150   mTOR signaling pathway elk04151   PI3K-Akt signaling pathway elk04261   Adrenergic signaling in cardiomyocytes elk04270   Vascular smooth muscle contraction elk04310   Wnt signaling pathway elk04360   Axon guidance elk04370   VEGF signaling pathway elk04510   Focal adhesion elk04540   Gap junction elk04650   Natural killer cell mediated cytotoxicity elk04664   Fc epsilon RI signaling pathway elk04666   Fc gamma R-mediated phagocytosis elk04670   Leukocyte transendothelial migration elk04713   Circadian entrainment elk04720   Long-term potentiation elk04723   Retrograde endocannabinoid signaling elk04724   Glutamatergic synapse elk04725   Cholinergic synapse elk04726   Serotonergic synapse elk04727   GABAergic synapse elk04728   Dopaminergic synapse elk04730   Long-term depression elk04750   Inflammatory mediator regulation of TRP channels elk04911   Insulin secretion elk04912   GnRH signaling pathway elk04916   Melanogenesis elk04918   Thyroid hormone synthesis elk04919   Thyroid hormone signaling pathway elk04921   Oxytocin signaling pathway elk04925   Aldosterone synthesis and secretion elk04926   Relaxin signaling pathway elk04928   Parathyroid hormone synthesis, secretion and action elk04929   GnRH secretion elk04933   AGE-RAGE signaling pathway in diabetic complications elk04935   Growth hormone synthesis, secretion and action elk04960   Aldosterone-regulated sodium reabsorption elk04961   Endocrine and other factor-regulated calcium reabsorption elk04970   Salivary secretion elk04971   Gastric acid secretion elk04972   Pancreatic secretion elk05017   Spinocerebellar ataxia elk05022   Pathways of neurodegeneration - multiple diseases elk05031   Amphetamine addiction elk05032   Morphine addiction elk05143   African trypanosomiasis elk05146   Amoebiasis elk05161   Hepatitis B elk05163   Human cytomegalovirus infection elk05164   Influenza A elk05170   Human immunodeficiency virus 1 infection elk05171   Coronavirus disease - COVID-19 elk05200   Pathways in cancer elk05205   Proteoglycans in cancer elk05206   MicroRNAs in cancer elk05214   Glioma elk05223   Non-small cell lung cancer elk05225   Hepatocellular carcinoma elk05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:elk00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     111158087    04012 ErbB signaling pathway     111158087    04014 Ras signaling pathway     111158087    04015 Rap1 signaling pathway     111158087    04310 Wnt signaling pathway     111158087    04370 VEGF signaling pathway     111158087    04066 HIF-1 signaling pathway     111158087    04020 Calcium signaling pathway     111158087    04070 Phosphatidylinositol signaling system     111158087    04072 Phospholipase D signaling pathway     111158087    04071 Sphingolipid signaling pathway     111158087    04151 PI3K-Akt signaling pathway     111158087    04150 mTOR signaling pathway     111158087  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     111158087    04540 Gap junction     111158087  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     111158087    04664 Fc epsilon RI signaling pathway     111158087    04666 Fc gamma R-mediated phagocytosis     111158087    04670 Leukocyte transendothelial migration     111158087   09152 Endocrine system    04911 Insulin secretion     111158087    04929 GnRH secretion     111158087    04912 GnRH signaling pathway     111158087    04921 Oxytocin signaling pathway     111158087    04926 Relaxin signaling pathway     111158087    04935 Growth hormone synthesis, secretion and action     111158087    04918 Thyroid hormone synthesis     111158087    04919 Thyroid hormone signaling pathway     111158087    04928 Parathyroid hormone synthesis, secretion and action     111158087    04916 Melanogenesis     111158087    04925 Aldosterone synthesis and secretion     111158087   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     111158087    04270 Vascular smooth muscle contraction     111158087   09154 Digestive system    04970 Salivary secretion     111158087    04971 Gastric acid secretion     111158087    04972 Pancreatic secretion     111158087   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     111158087    04961 Endocrine and other factor-regulated calcium reabsorption     111158087   09156 Nervous system    04724 Glutamatergic synapse     111158087    04727 GABAergic synapse     111158087    04725 Cholinergic synapse     111158087    04728 Dopaminergic synapse     111158087    04726 Serotonergic synapse     111158087    04720 Long-term potentiation     111158087    04730 Long-term depression     111158087    04723 Retrograde endocannabinoid signaling     111158087   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     111158087   09158 Development and regeneration    04360 Axon guidance     111158087   09159 Environmental adaptation    04713 Circadian entrainment     111158087  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111158087    05206 MicroRNAs in cancer     111158087    05205 Proteoglycans in cancer     111158087    05231 Choline metabolism in cancer     111158087   09162 Cancer: specific types    05225 Hepatocellular carcinoma     111158087    05214 Glioma     111158087    05223 Non-small cell lung cancer     111158087   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     111158087    05022 Pathways of neurodegeneration - multiple diseases     111158087   09165 Substance dependence    05031 Amphetamine addiction     111158087    05032 Morphine addiction     111158087   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     111158087   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     111158087    05161 Hepatitis B     111158087    05171 Coronavirus disease - COVID-19     111158087    05164 Influenza A     111158087    05163 Human cytomegalovirus infection     111158087   09174 Infectious disease: parasitic    05146 Amoebiasis     111158087    05143 African trypanosomiasis     111158087   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     111158087  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:elk01001]     111158087   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:elk04131]     111158087 Enzymes [BR:elk01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      111158087 Protein kinases [BR:elk01001]  Serine/threonine kinases: AGC group   PKC family [OT]    111158087 Membrane trafficking [BR:elk04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     111158087 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 APH Motif Other DBs NCBI-GeneID:  111158087 NCBI-ProteinID:  XP_022375624 UniProt:  A0A2Y9KWD6 LinkDB All DBs Position Unknown AA seq 672 aa AA seqDB search MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE LRQKFEKAKLGPAGNKVISPSEDRRQTSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRI DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN PQFVHPILQSAV NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccacgag tttgtcactttttcttgtccgggtgcggataagggacctgacaccgatgaccccagaagc aagcacaagttcaaaatccacacctatggaagccccaccttctgtgatcactgtggctcc ttgctgtatggacttattcatcaagggatgaaatgtgacacctgtgacatgaacgtgcac aagcagtgcgtgatcaacgtgcccagcctctgcgggatggaccacacggagaagcggggc cgcatctacctgaaggccgaggtcaccgacgagaagctccacgtcaccgtacgcgatgca aaaaatctaattcctatggatccaaatgggctttcagatccttatgtgaagctgaaactt attcctgatcccaagaatgaaagcaaacagaaaaccaaaactatccgctccacattaaac ccccagtggaatgagtcttttacgttcaagttaaagccttcggataaagaccgacgactg tccgtagaaatctgggactgggatcgaacaacaaggaatgatttcatgggctccctttcc tttggcgtctcggagctgatgaagatgccggccagcggatggtacaagctgcttaaccaa gaggaaggtgagtactacaatgtgcccattccagaaggggatgaagaaggcaacgtggag ctcaggcagaagttcgagaaagccaagcttggccctgctggtaacaaagtcatcagtcct tcagaagacaggagacaaacttccaacaacctggacagagtgaaactcaccgacttcaat ttcctcatggtgctggggaaggggagttttggaaaggtgatgctcgctgaccggaagggc acagaggaactgtatgccatcaaaatcctgaagaaggacgtggtgattcaagatgacgac gtggagtgcaccatggtggagaagcgagtcctggccctgctggacaagcccccgttcctg acacagctacactcctgcttccagaccgtggaccggctgtatttcgtcatggaatacgtc aatggcggggacctcatgtaccacattcagcaagtgggaaaatttaaggaaccacaagca gtattttatgcagcagaaatttccattggattgttctttcttcataaaaggggaatcata tacagggatctgaagttagataatgtcatgctggattcggaagggcatatcaagattgct gattttgggatgtgcaaggaacacatgatggatggggtcaccaccaggaccttctgtggg acaccggattacatcgccccagagataatcgcgtatcagccgtatggaaaatccgtggac tggtgggcctacggtgtcctattatatgaaatgctagccgggcagcctccctttgacggc gaagacgaagacgagctatttcagtccataatggagcataacgtctcttatcccaaatcc ttgtccaaggaggccgtttccatctgcaaaggactgatgaccaaacacccaggcaagcgg ctgggttgcgggccagagggggagagggatgtgcgggagcatgccttcttccggaggatc gactgggagaaacttgagaacagggagatccagccgcccttcaagcccaaagtgtgtggc aaaggcgcagaaaactttgacaagttcttcacgcgagggcagcccgtcttgacaccaccc gatcagctggtcattgctaacatagaccagtctgatttcgaggggttctcgtatgtcaac ccccagtttgtgcaccccatcttacagagcgcagtatga

Enhydra lutris kenyoni (northern sea otter): 111162208 Help Entry 111162208         CDS       T05871                                  Definition (RefSeq) protein kinase C beta type isoform X1   KO K19662   classical protein kinase C beta type [EC:2.7.11.13] Organism elk  Enhydra lutris kenyoni (northern sea otter) Pathway elk01521   EGFR tyrosine kinase inhibitor resistance elk04010   MAPK signaling pathway elk04012   ErbB signaling pathway elk04014   Ras signaling pathway elk04015   Rap1 signaling pathway elk04020   Calcium signaling pathway elk04062   Chemokine signaling pathway elk04064   NF-kappa B signaling pathway elk04066   HIF-1 signaling pathway elk04070   Phosphatidylinositol signaling system elk04071   Sphingolipid signaling pathway elk04150   mTOR signaling pathway elk04270   Vascular smooth muscle contraction elk04310   Wnt signaling pathway elk04370   VEGF signaling pathway elk04510   Focal adhesion elk04540   Gap junction elk04650   Natural killer cell mediated cytotoxicity elk04662   B cell receptor signaling pathway elk04666   Fc gamma R-mediated phagocytosis elk04670   Leukocyte transendothelial migration elk04713   Circadian entrainment elk04720   Long-term potentiation elk04723   Retrograde endocannabinoid signaling elk04724   Glutamatergic synapse elk04725   Cholinergic synapse elk04726   Serotonergic synapse elk04727   GABAergic synapse elk04728   Dopaminergic synapse elk04730   Long-term depression elk04750   Inflammatory mediator regulation of TRP channels elk04911   Insulin secretion elk04912   GnRH signaling pathway elk04916   Melanogenesis elk04918   Thyroid hormone synthesis elk04919   Thyroid hormone signaling pathway elk04921   Oxytocin signaling pathway elk04925   Aldosterone synthesis and secretion elk04928   Parathyroid hormone synthesis, secretion and action elk04929   GnRH secretion elk04931   Insulin resistance elk04933   AGE-RAGE signaling pathway in diabetic complications elk04935   Growth hormone synthesis, secretion and action elk04960   Aldosterone-regulated sodium reabsorption elk04961   Endocrine and other factor-regulated calcium reabsorption elk04970   Salivary secretion elk04971   Gastric acid secretion elk04972   Pancreatic secretion elk04973   Carbohydrate digestion and absorption elk05017   Spinocerebellar ataxia elk05022   Pathways of neurodegeneration - multiple diseases elk05031   Amphetamine addiction elk05032   Morphine addiction elk05140   Leishmaniasis elk05143   African trypanosomiasis elk05146   Amoebiasis elk05161   Hepatitis B elk05163   Human cytomegalovirus infection elk05164   Influenza A elk05170   Human immunodeficiency virus 1 infection elk05171   Coronavirus disease - COVID-19 elk05200   Pathways in cancer elk05205   Proteoglycans in cancer elk05206   MicroRNAs in cancer elk05214   Glioma elk05223   Non-small cell lung cancer elk05225   Hepatocellular carcinoma elk05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:elk00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     111162208    04012 ErbB signaling pathway     111162208    04014 Ras signaling pathway     111162208    04015 Rap1 signaling pathway     111162208    04310 Wnt signaling pathway     111162208    04370 VEGF signaling pathway     111162208    04064 NF-kappa B signaling pathway     111162208    04066 HIF-1 signaling pathway     111162208    04020 Calcium signaling pathway     111162208    04070 Phosphatidylinositol signaling system     111162208    04071 Sphingolipid signaling pathway     111162208    04150 mTOR signaling pathway     111162208  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     111162208    04540 Gap junction     111162208  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     111162208    04662 B cell receptor signaling pathway     111162208    04666 Fc gamma R-mediated phagocytosis     111162208    04670 Leukocyte transendothelial migration     111162208    04062 Chemokine signaling pathway     111162208   09152 Endocrine system    04911 Insulin secretion     111162208    04929 GnRH secretion     111162208    04912 GnRH signaling pathway     111162208    04921 Oxytocin signaling pathway     111162208    04935 Growth hormone synthesis, secretion and action     111162208    04918 Thyroid hormone synthesis     111162208    04919 Thyroid hormone signaling pathway     111162208    04928 Parathyroid hormone synthesis, secretion and action     111162208    04916 Melanogenesis     111162208    04925 Aldosterone synthesis and secretion     111162208   09153 Circulatory system    04270 Vascular smooth muscle contraction     111162208   09154 Digestive system    04970 Salivary secretion     111162208    04971 Gastric acid secretion     111162208    04972 Pancreatic secretion     111162208    04973 Carbohydrate digestion and absorption     111162208   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     111162208    04961 Endocrine and other factor-regulated calcium reabsorption     111162208   09156 Nervous system    04724 Glutamatergic synapse     111162208    04727 GABAergic synapse     111162208    04725 Cholinergic synapse     111162208    04728 Dopaminergic synapse     111162208    04726 Serotonergic synapse     111162208    04720 Long-term potentiation     111162208    04730 Long-term depression     111162208    04723 Retrograde endocannabinoid signaling     111162208   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     111162208   09159 Environmental adaptation    04713 Circadian entrainment     111162208  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111162208    05206 MicroRNAs in cancer     111162208    05205 Proteoglycans in cancer     111162208    05231 Choline metabolism in cancer     111162208   09162 Cancer: specific types    05225 Hepatocellular carcinoma     111162208    05214 Glioma     111162208    05223 Non-small cell lung cancer     111162208   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     111162208    05022 Pathways of neurodegeneration - multiple diseases     111162208   09165 Substance dependence    05031 Amphetamine addiction     111162208    05032 Morphine addiction     111162208   09167 Endocrine and metabolic disease    04931 Insulin resistance     111162208    04933 AGE-RAGE signaling pathway in diabetic complications     111162208   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     111162208    05161 Hepatitis B     111162208    05171 Coronavirus disease - COVID-19     111162208    05164 Influenza A     111162208    05163 Human cytomegalovirus infection     111162208   09174 Infectious disease: parasitic    05146 Amoebiasis     111162208    05140 Leishmaniasis     111162208    05143 African trypanosomiasis     111162208   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     111162208  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:elk01001]     111162208 Enzymes [BR:elk01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      111162208 Protein kinases [BR:elk01001]  Serine/threonine kinases: AGC group   PKC family [OT]    111162208 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 Kinase-like CEP76-C2 APH Motif Other DBs NCBI-GeneID:  111162208 NCBI-ProteinID:  XP_022382145 UniProt:  A0A2Y9LK98 LinkDB All DBs Position Unknown AA seq 673 aa AA seqDB search MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE LRQKFERAKISQGTKAPEEKTTNTISKLDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF RYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFS FVNSEFLKPEVKS NT seq 2022 nt NT seq  +upstreamnt  +downstreamnt atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttc gcccgcaaaggcgccctccggcagaagaacgtgcacgaggtgaagaaccacaaattcacc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc gggaagcaaggattccagtgccaagtctgctgttttgtcgtgcacaagcggtgccatgaa ttcgtcaccttctcctgcccaggtgccgacaaaggcccagcctctgatgatccccggagc aaacacaagtttaagatccacacgtactccagccccacgttttgtgaccactgtgggtca ctgctgtacggactcatccaccaggggatgaaatgtgacacctgcatgatgaacgtgcac aagcgctgcgtgatgaacgtccccagcctgtgcggcacagaccacacggagcgccgcggc cgcatctacatccaggcccacattgagagggaagtcctcatcgtcgtcgtaagagatgct aaaaaccttgtacctatggaccccaatggcttgtcagacccttacgtgaaactgaaactg attcccgaccccaagagcgagagcaagcagaagaccaaaaccatcaaatgctccctcaac cctgagtggaacgagacattcagattccagttgaaagaatcggacaaagacagaagactg tccgtggagatttgggactgggatctgaccagcaggaatgacttcatgggatctttgtcg tttgggatttccgaactgcagaaagctggtgttgatggctggttcaagttgctgagccag gaggaaggcgagtacttcaacgtgcctgtgccgccagaaggaagcgagggcaatgaagag ctgaggcagaaattcgagagagccaagatcagtcaggggaccaaggctccggaagaaaag acgaccaataccatatccaaacttgacaacaatgggaacagagaccgaatgaaactgact gattttaacttcctgatggtgctcgggaaaggaagctttggcaaggtcatgctctccgag cggaaaggcacggacgagctctacgccgtgaagatcctgaagaaggacgtggtgatccag gacgacgacgtggagtgcacgatggtggagaagcgggtgctggccctgccagggaagccg ccgttcctgacccagctgcattcctgcttccagaccatggaccgcctgtactttgtgatg gagtacgtgaacgggggtgacctcatgtaccacatccagcaagttggccggtttaaggag cctcatgctgtattttacgctgcagaaattgccatcggtctgttcttcttgcagagcaag ggcatcatttaccgtgacctcaaacttgacaatgtgatgctggattcagagggccacatc aagattgctgattttggcatgtgtaaggaaaacatctgggatggggtgaccactaagaca ttctgtggaactccagactacatcgcccctgagatcattgcctaccagccctacgggaag tctgtggattggtgggccttcggagtcctgctgtatgaaatgttggctgggcaggcaccc tttgaaggcgaggatgaggatgagctcttccagtccatcatggaacacaacgtggcttac cccaagtccatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccg ggcaaacgcctggggtgcggacccgaaggtgaacgcgacatcaaggagcacgcgtttttc cggtatattgattgggagaaactggagcgcaaagagatccagcccccgtacaagccaaaa gcctgtgggcgaaatgctgaaaacttcgaccggtttttcacccgccatccaccagtccta acacctcccgaccaggaagtcatcaggaatattgaccagtcagaattcgaaggattttcc tttgttaactctgaatttttaaaacctgaagtcaagagctaa

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