KEGG   ORTHOLOGY: K19663
Entry
K19663                      KO                                     
Symbol
PRKCG
Name
classical protein kinase C gamma type [EC:2.7.11.13]
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map04010  MAPK signaling pathway
map04012  ErbB signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04066  HIF-1 signaling pathway
map04070  Phosphatidylinositol signaling system
map04071  Sphingolipid signaling pathway
map04150  mTOR signaling pathway
map04270  Vascular smooth muscle contraction
map04310  Wnt signaling pathway
map04370  VEGF signaling pathway
map04510  Focal adhesion
map04540  Gap junction
map04613  Neutrophil extracellular trap formation
map04650  Natural killer cell mediated cytotoxicity
map04666  Fc gamma R-mediated phagocytosis
map04670  Leukocyte transendothelial migration
map04713  Circadian entrainment
map04720  Long-term potentiation
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04727  GABAergic synapse
map04728  Dopaminergic synapse
map04730  Long-term depression
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04919  Thyroid hormone signaling pathway
map04921  Oxytocin signaling pathway
map04925  Aldosterone synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04929  GnRH secretion
map04935  Growth hormone synthesis, secretion and action
map04960  Aldosterone-regulated sodium reabsorption
map04961  Endocrine and other factor-regulated calcium reabsorption
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map05017  Spinocerebellar ataxia
map05022  Pathways of neurodegeneration - multiple diseases
map05031  Amphetamine addiction
map05032  Morphine addiction
map05143  African trypanosomiasis
map05146  Amoebiasis
map05161  Hepatitis B
map05163  Human cytomegalovirus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05214  Glioma
map05223  Non-small cell lung cancer
map05225  Hepatocellular carcinoma
map05231  Choline metabolism in cancer
map05415  Diabetic cardiomyopathy
Disease
H00063  Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04012 ErbB signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04014 Ras signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04015 Rap1 signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04310 Wnt signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04370 VEGF signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04066 HIF-1 signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04020 Calcium signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04070 Phosphatidylinositol signaling system
    K19663  PRKCG; classical protein kinase C gamma type
   04071 Sphingolipid signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04150 mTOR signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K19663  PRKCG; classical protein kinase C gamma type
   04540 Gap junction
    K19663  PRKCG; classical protein kinase C gamma type
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K19663  PRKCG; classical protein kinase C gamma type
   04650 Natural killer cell mediated cytotoxicity
    K19663  PRKCG; classical protein kinase C gamma type
   04666 Fc gamma R-mediated phagocytosis
    K19663  PRKCG; classical protein kinase C gamma type
   04670 Leukocyte transendothelial migration
    K19663  PRKCG; classical protein kinase C gamma type
  09152 Endocrine system
   04911 Insulin secretion
    K19663  PRKCG; classical protein kinase C gamma type
   04929 GnRH secretion
    K19663  PRKCG; classical protein kinase C gamma type
   04921 Oxytocin signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04935 Growth hormone synthesis, secretion and action
    K19663  PRKCG; classical protein kinase C gamma type
   04918 Thyroid hormone synthesis
    K19663  PRKCG; classical protein kinase C gamma type
   04919 Thyroid hormone signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04928 Parathyroid hormone synthesis, secretion and action
    K19663  PRKCG; classical protein kinase C gamma type
   04916 Melanogenesis
    K19663  PRKCG; classical protein kinase C gamma type
   04925 Aldosterone synthesis and secretion
    K19663  PRKCG; classical protein kinase C gamma type
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K19663  PRKCG; classical protein kinase C gamma type
  09154 Digestive system
   04970 Salivary secretion
    K19663  PRKCG; classical protein kinase C gamma type
   04971 Gastric acid secretion
    K19663  PRKCG; classical protein kinase C gamma type
   04972 Pancreatic secretion
    K19663  PRKCG; classical protein kinase C gamma type
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K19663  PRKCG; classical protein kinase C gamma type
   04961 Endocrine and other factor-regulated calcium reabsorption
    K19663  PRKCG; classical protein kinase C gamma type
  09156 Nervous system
   04724 Glutamatergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04727 GABAergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04725 Cholinergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04728 Dopaminergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04726 Serotonergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04720 Long-term potentiation
    K19663  PRKCG; classical protein kinase C gamma type
   04730 Long-term depression
    K19663  PRKCG; classical protein kinase C gamma type
   04723 Retrograde endocannabinoid signaling
    K19663  PRKCG; classical protein kinase C gamma type
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K19663  PRKCG; classical protein kinase C gamma type
  09159 Environmental adaptation
   04713 Circadian entrainment
    K19663  PRKCG; classical protein kinase C gamma type
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K19663  PRKCG; classical protein kinase C gamma type
   05206 MicroRNAs in cancer
    K19663  PRKCG; classical protein kinase C gamma type
   05205 Proteoglycans in cancer
    K19663  PRKCG; classical protein kinase C gamma type
   05207 Chemical carcinogenesis - receptor activation
    K19663  PRKCG; classical protein kinase C gamma type
   05231 Choline metabolism in cancer
    K19663  PRKCG; classical protein kinase C gamma type
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K19663  PRKCG; classical protein kinase C gamma type
   05214 Glioma
    K19663  PRKCG; classical protein kinase C gamma type
   05223 Non-small cell lung cancer
    K19663  PRKCG; classical protein kinase C gamma type
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K19663  PRKCG; classical protein kinase C gamma type
   05161 Hepatitis B
    K19663  PRKCG; classical protein kinase C gamma type
   05171 Coronavirus disease - COVID-19
    K19663  PRKCG; classical protein kinase C gamma type
   05163 Human cytomegalovirus infection
    K19663  PRKCG; classical protein kinase C gamma type
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K19663  PRKCG; classical protein kinase C gamma type
   05143 African trypanosomiasis
    K19663  PRKCG; classical protein kinase C gamma type
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K19663  PRKCG; classical protein kinase C gamma type
   05022 Pathways of neurodegeneration - multiple diseases
    K19663  PRKCG; classical protein kinase C gamma type
  09165 Substance dependence
   05031 Amphetamine addiction
    K19663  PRKCG; classical protein kinase C gamma type
   05032 Morphine addiction
    K19663  PRKCG; classical protein kinase C gamma type
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K19663  PRKCG; classical protein kinase C gamma type
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K19663  PRKCG; classical protein kinase C gamma type
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K19663  PRKCG; classical protein kinase C gamma type
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     K19663  PRKCG; classical protein kinase C gamma type
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   K19663  PRKCG; classical protein kinase C gamma type
Other DBs
GO: 0004697
Genes
HSA: 5582(PRKCG)
PTR: 456276(PRKCG)
PPS: 100990245(PRKCG)
GGO: 101139074(PRKCG)
PON: 100451563(PRKCG)
PPYG: 129019849(PRKCG)
NLE: 100601464(PRKCG)
HMH: 116479165(PRKCG)
SSYN: 129460671(PRKCG)
MCC: 720263(PRKCG)
MCF: 101865773(PRKCG)
MTHB: 126943319
MNI: 105497021(PRKCG)
CSAB: 103235232(PRKCG)
CATY: 105595654(PRKCG)
PANU: 100137333(PRKCG)
TGE: 112613317(PRKCG)
MLEU: 105539692(PRKCG)
RRO: 104676027(PRKCG)
RBB: 108529452(PRKCG)
TFN: 117091710(PRKCG)
PTEH: 111530493(PRKCG)
CANG: 105524211(PRKCG)
CJC: 100404028(PRKCG)
SBQ: 101032613(PRKCG)
CIMI: 108282129(PRKCG)
ANAN: 105732524(PRKCG)
CSYR: 103276479(PRKCG)
MMUR: 105874723(PRKCG)
LCAT: 123624654(PRKCG)
PCOQ: 105809569(PRKCG)
OGA: 100956877(PRKCG)
MMU: 18752(Prkcg)
MCAL: 110297763(Prkcg)
MPAH: 110336366(Prkcg)
RNO: 24681(Prkcg)
MCOC: 116101512(Prkcg)
ANU: 117701003(Prkcg)
MUN: 110556016(Prkcg)
CGE: 100762950(Prkcg)
MAUA: 101828136(Prkcg)
PROB: 127238613(Prkcg)
PLEU: 114687523(Prkcg)
MORG: 121449728(Prkcg)
MFOT: 126493096
AAMP: 119820784(Prkcg)
NGI: 103729666(Prkcg)
HGL: 101698346(Prkcg)
CPOC: 100733947(Prkcg)
CCAN: 109693140(Prkcg)
DORD: 105994311(Prkcg)
DSP: 122110671(Prkcg)
PLOP: 125338673(Prkcg)
NCAR: 124967611
MMMA: 107158898(Prkcg)
OCU: 100009102(PRKCG)
OPI: 101534827(PRKCG)
TUP: 102497204(PRKCG)
GVR: 103583388 103599669(PRKCG)
CFA: 100855828(PRKCG)
CLUD: 112645036(PRKCG)
VVP: 112909321(PRKCG)
VLG: 121480810(PRKCG)
NPO: 129500385(PRKCG)
AML: 100484719(PRKCG)
UMR: 103672914(PRKCG)
UAH: 113247385(PRKCG)
UAR: 123786995(PRKCG)
ELK: 111139613
LLV: 125089171
MPUF: 101671536(PRKCG)
MNP: 132004993(PRKCG)
MLK: 131818861(PRKCG)
NVS: 122911685(PRKCG)
ORO: 101363254(PRKCG)
EJU: 114201798(PRKCG)
ZCA: 113935801(PRKCG)
MLX: 117997993(PRKCG)
NSU: 110573626(PRKCG)
LWW: 102741890(PRKCG)
FCA: 101082196(PRKCG)
PYU: 121018827(PRKCG)
PCOO: 112850908(PRKCG)
PBG: 122494748(PRKCG)
PVIV: 125153700(PRKCG)
LRUF: 124527789
PTG: 102956490(PRKCG)
PPAD: 109259277(PRKCG)
PUC: 125915497
AJU: 106980855
HHV: 120239766(PRKCG)
BTA: 282002(PRKCG)
BOM: 102265831(PRKCG)
BIU: 109572998(PRKCG)
BBUB: 102397646(PRKCG)
BBIS: 105000236(PRKCG)
CHX: 102175984(PRKCG)
OAS: 101116423(PRKCG)
BTAX: 128063096(PRKCG)
ODA: 120871941(PRKCG)
CCAD: 122420171(PRKCG)
MBEZ: 129546400(PRKCG)
SSC: 100518074(PRKCG)
CFR: 102513516(PRKCG)
CBAI: 105074322(PRKCG)
CDK: 105103265(PRKCG)
VPC: 102542323(PRKCG)
BACU: 103017540(PRKCG)
BMUS: 118884764(PRKCG)
LVE: 103086653(PRKCG)
OOR: 101276418(PRKCG)
DLE: 111180981(PRKCG)
PCAD: 102983841(PRKCG)
PSIU: 116743766(PRKCG)
NASI: 112397907(PRKCG)
ECB: 100062549(PRKCG)
EPZ: 103556196(PRKCG)
EAI: 106840859(PRKCG)
MYB: 102249897(PRKCG)
MYD: 102756030(PRKCG)
MMYO: 118660957(PRKCG)
MLF: 102419083
MDT: 132216549(PRKCG)
PKL: 118719731(PRKCG)
EFUS: 103303678(PRKCG)
MNA: 107540426(PRKCG)
DRO: 112321262(PRKCG)
SHON: 118986634(PRKCG)
AJM: 119036009(PRKCG)
PDIC: 114511158(PRKCG)
PHAS: 123824140(PRKCG)
MMF: 118638191(PRKCG)
PPAM: 129081586(PRKCG)
HAI: 109372505(PRKCG)
RFQ: 117035150(PRKCG)
PALE: 102888961(PRKCG)
PGIG: 120616484(PRKCG)
PVP: 105309462(PRKCG)
RAY: 107503061(PRKCG)
MJV: 108395733(PRKCG)
TOD: 119249714(PRKCG)
SARA: 101539279(PRKCG)
SETR: 126027978(PRKCG)
LAV: 100671733(PRKCG)
TMU: 101351254
ETF: 101651846(PRKCG)
DNM: 101447351(PRKCG)
SHR: 100935225(PRKCG)
AFZ: 127556522
PCW: 110220182(PRKCG)
TVP: 118839200(PRKCG)
OAA: 100085442(PRKCG)
CJO: 107307120
GFR: 102040754
PHI: 102099121
FPG: 101910888(CACNG7)
FCH: 102049511
SHAB: 115602904(PRKCG)
CUCA: 104064246(PRKCG)
RTD: 128903859
ASN: 102371860(PRKCG)
AMJ: 102574559(PRKCG)
PSS: 102459783
CMY: 102932331(PRKCG)
CCAY: 125627876(PRKCG)
DCC: 119847377(PRKCG)
CPIC: 101937053(PRKCG)
TST: 117870501(PRKCG)
CABI: 116832380
MRV: 120388263(PRKCG)
ACS: 100559682(prkcg)
ASAO: 132777885(PRKCG)
PVT: 110078510(PRKCG)
SUND: 121932615(PRKCG)
PBI: 103055466(PRKCG)
CTIG: 120304480(PRKCG)
TSR: 106538053(PRKCG)
PGUT: 117666672(PRKCG)
APRI: 131198774(PRKCG)
PTEX: 113443569(PRKCG)
NSS: 113418514(PRKCG)
VKO: 123032105(PRKCG)
PMUA: 114581744(PRKCG)
PRAF: 128399462(PRKCG)
ZVI: 118094978(PRKCG)
HCG: 128329341(PRKCG)
GJA: 107113125(PRKCG)
STOW: 125444571(PRKCG)
EMC: 129338720(PRKCG)
XTR: 100496779(prkcg)
NPR: 108797498(PRKCG)
RTEM: 120915291(PRKCG)
BBUF: 121003127(PRKCG)
BGAR: 122926643(PRKCG)
MUO: 115466532(PRKCG)
GSH: 117368368(PRKCG)
DRE: 100003514(prkcg)
LROH: 127178761(prkcg)
OMC: 131521212(prkcg)
PPRM: 120484709(prkcg)
RKG: 130103639(prkcg)
MAMB: 125242974(prkcg)
CIDE: 127497283
CERY: 137025670(prkcg)
TROS: 130557446(prkcg)
TDW: 130433482(prkcg)
MANU: 129447854(prkcg)
IPU: 108266582(prkcg)
IFU: 128608413(prkcg)
PHYP: 113542453
SMEO: 124384840(prkcg)
TFD: 113643727(prkcg)
TVC: 132845349(prkcg)
TRN: 134310216(prkcg)
AMEX: 103042824(prkcg)
CMAO: 118824989(prkcg)
CHAR: 105894611(prkcg)
TRU: 101079823
TFS: 130532931(prkcg)
LCO: 104929793
NCC: 104960432
TBEN: 117480431(prkcg)
CGOB: 115021190
PGEO: 117461588(prkcg)
GACU: 117543213(prkcg)
EMAC: 134861768(prkcg)
ELY: 117265709(prkcg)
EFO: 125893640(prkcg)
PLEP: 121945942(prkcg)
SLUC: 116049652(prkcg)
ECRA: 117946209(prkcg)
ESP: 116691362
PFLV: 114557331
GAT: 120809973(prkcg)
PPUG: 119198242(prkcg)
AFB: 129109298(prkcg)
CLUM: 117745270(prkcg)
PSWI: 130213123(prkcg)
MSAM: 119897496(prkcg)
SCHU: 122882022(prkcg)
CUD: 121513601(prkcg)
ALAT: 119006482(prkcg)
ASTR: 137601235(prkcg)
MZE: 101481445
ONL: 100699493
OAU: 116323881(prkcg)
OLA: 101164921
OML: 112143416(prkcg)
CSAI: 133433875(prkcg)
XMA: 102229029
XCO: 114141948
XHE: 116716059
PRET: 103478059
PFOR: 103136673
PLAI: 106938420
PMEI: 106931041
GAF: 122830524(prkcg)
PPRL: 129371521(prkcg)
CVG: 107100308
CTUL: 119782956(prkcg)
GMU: 124866124(prkcg)
NFU: 107379571
KMR: 108235495(prkcg)
ALIM: 106520517
NWH: 119409381(prkcg)
AOCE: 111569071
MCEP: 125015974(prkcg)
CSEM: 103387841
POV: 109633056
SSEN: 122774138(prkcg)
HHIP: 117777363(prkcg)
HSP: 118113177(prkcg)
PPLT: 128449406(prkcg)
SMAU: 118314827(prkcg)
LCF: 108887298(prkcg)
SDU: 111230118
SLAL: 111669824
XGL: 120784226(prkcg)
HCQ: 109515431
SSCV: 125975667
SBIA: 133501023(prkcg)
PEE: 133401470(prkcg)
PTAO: 133480082(prkcg)
BPEC: 110163020
MALB: 109970170
BSPL: 114843025(prkcg)
SJO: 128365943(prkcg)
OMY: 110512786 118945770(prkcg)
OGO: 124005945
OKI: 109886787
SNH: 120036642
ELS: 105019084
SFM: 108924427
PKI: 111853291
AANG: 118221921(prkcg)
PSPA: 121302494(prkcg)
PSEX: 120518916
LCM: 102352260(PRKCG)
SCLV: 120333729
 » show all
Reference
  Authors
Saito N, Shirai Y
  Title
Protein kinase C gamma (PKC gamma): function of neuron specific isotype.
  Journal
J Biochem 132:683-7 (2002)
DOI:10.1093/oxfordjournals.jbchem.a003274
  Sequence
[hsa:5582]
Reference
PMID:3755548
  Authors
Coussens L, Parker PJ, Rhee L, Yang-Feng TL, Chen E, Waterfield MD, Francke U, Ullrich A
  Title
Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.
  Journal
Science 233:859-66 (1986)
DOI:10.1126/science.3755548
  Sequence
[hsa:5582]
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