Heterocephalus glaber (naked mole rat): 101717788 Entry 101717788         CDS       T02812                                  Gene name Shc4 Definition (RefSeq) SHC adaptor protein 4   KO K17449   SHC-transforming protein 4 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl01522   Endocrine resistance hgl04012   ErbB signaling pathway hgl04014   Ras signaling pathway hgl04062   Chemokine signaling pathway hgl04072   Phospholipase D signaling pathway hgl04510   Focal adhesion hgl04650   Natural killer cell mediated cytotoxicity hgl04722   Neurotrophin signaling pathway hgl04910   Insulin signaling pathway hgl04915   Estrogen signaling pathway hgl04917   Prolactin signaling pathway hgl04926   Relaxin signaling pathway hgl04935   Growth hormone synthesis, secretion and action hgl05034   Alcoholism hgl05100   Bacterial invasion of epithelial cells hgl05206   MicroRNAs in cancer hgl05214   Glioma hgl05220   Chronic myeloid leukemia hgl05224   Breast cancer hgl05225   Hepatocellular carcinoma hgl05226   Gastric cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     101717788 (Shc4)    04012 ErbB signaling pathway     101717788 (Shc4)    04072 Phospholipase D signaling pathway     101717788 (Shc4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     101717788 (Shc4)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     101717788 (Shc4)    04062 Chemokine signaling pathway     101717788 (Shc4)   09152 Endocrine system    04910 Insulin signaling pathway     101717788 (Shc4)    04915 Estrogen signaling pathway     101717788 (Shc4)    04917 Prolactin signaling pathway     101717788 (Shc4)    04926 Relaxin signaling pathway     101717788 (Shc4)    04935 Growth hormone synthesis, secretion and action     101717788 (Shc4)   09156 Nervous system    04722 Neurotrophin signaling pathway     101717788 (Shc4)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     101717788 (Shc4)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     101717788 (Shc4)    05226 Gastric cancer     101717788 (Shc4)    05214 Glioma     101717788 (Shc4)    05220 Chronic myeloid leukemia     101717788 (Shc4)    05224 Breast cancer     101717788 (Shc4)   09165 Substance dependence    05034 Alcoholism     101717788 (Shc4)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     101717788 (Shc4)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101717788 (Shc4)    01522 Endocrine resistance     101717788 (Shc4) SSDB Motif Pfam:  PID SH2 Delta_lysin Other DBs NCBI-GeneID:  101717788 NCBI-ProteinID:  XP_012929931 LinkDB Position Un AA seq 533 aa MRGSGQDSLTGLALCAGLSGPPGMLQRAKYSRFRNEPVQLAEEGGSKGAPQPARLAREPP EDSASPTRDGPTPLCTLVPRVASVKLANPAALLSLKNFCLGTKEAPGPRVRESRDPAPAP PPPEPCLPGPAEPSVRGRRDQPGPKQHLLGAGLSYRVRYMGCIEVLQSMRSLDFGMRTQV TREAISRLCEAVPGASGAIKKRKAPVKFLSAVLGKSNLQFSGMNIKLTISTGSLTLMKLD NQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECRSGTAQDVISTIGQA FELRFKQYLRNTSLNISCESEEVQTDSPASEGEDHEYYNEIPGKQLPAGGVSDLRIRVQS PEQRAYCPIRCEKLCYLPGNSKSSSAYENCLEQSRAAEALEAVQPGATAQPTSSCSLLHI KQQLWNEDCYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGSQAKHLLLVDPE GKVRTKDHVFDNVGHLIRYHMDNSLPIISSGSEVTLKQPVRKEDNPGLLHFKK NT seq 1602 nt   +upstreamnt  +downstreamnt atgcgaggcagcggccaggacagtctgacggggctcgcgctgtgcgccgggctctcggga cccccggggatgctgcagcgggccaagtacagccgcttccgcaacgagccggtccagctg gccgaggagggcgggagcaagggcgccccgcagccggcccgcctcgcccgggagcccccc gaggactccgcctcgcccacccgggacggccctaccccgctgtgcaccctggtaccccgc gtggccagcgtgaagctggccaacccggccgctctgctgagcctgaagaacttttgcctg ggcaccaaggaggctcccgggccgagggtgcgggagagccgggaccccgcgccagccccg ccgccccccgagccctgcctgcccgggcccgcagagccgagcgtccggggcaggcgggac cagccgggcccgaagcagcacctgctgggagccggcctgagctaccgcgtacggtacatg ggctgcattgaagtgctgcaatcgatgaggtccctggatttcggaatgaggacccaagtt acaagggaagcgataagccgcctgtgtgaagctgtccctggggccagtggagccattaaa aagagaaaggctcctgttaagttcctctcagcagttcttggcaaaagtaatcttcagttt tctggaatgaatataaaactgaccatctcaacgggcagccttacactgatgaaacttgat aaccagcagatcattgcaaatcatcatatgcaatctatttcatttgcttctggaggggat cctgatactacagactatgttgcctacgtagctaaagatccagttaatcaacgagcatgc cacatattggaatgccgcagcggaacggcccaggatgtcataagcaccatcgggcaggct tttgaactccgattcaaacagtacttgagaaatacttctctgaacatttcttgtgaaagt gaggaggtgcagactgacagccccgcctcggagggagaagatcatgaatattacaacgag atcccaggcaagcagctgccggcaggcggcgtgtcagaccttcggatcagagtgcaaagc cctgagcagagggcgtactgccccattcgctgtgaaaagctgtgctacttgcctgggaac tccaagagcagcagtgcgtatgagaactgtctggaacaaagcagggcagcagaggccctg gaggccgtgcagcctggtgccacagcccagcccaccagctcatgttctttgctgcacatc aagcagcagctgtggaatgaagactgctaccatggcaagctgagcaggaaggcagcagag agccttctggtgaaggatggggactttttggttcgagagagtgcaacatcccccggccag tatgtactgagtggattacagggcagccaggcaaaacaccttctcctggtggatcctgaa ggcaaggtgaggaccaaggatcatgtattcgataatgttgggcaccttatcagataccat atggataacagtttgcccatcatctcttctggaagcgaagtaaccctcaaacaaccggtg agaaaagaagataaccccggacttttgcatttcaagaaatga

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