Homo sapiens (human): 1445 Entry 1445              CDS       T01001                                  Gene name CSK Definition (RefSeq) C-terminal Src kinase   KO K05728   c-src tyrosine kinase [EC:2.7.10.2] Organism hsa  Homo sapiens (human) Pathway hsa05120   Epithelial cell signaling in Helicobacter pylori infection Brite KEGG Orthology (KO) [BR:hsa00001]  09160 Human Diseases   09171 Infectious disease: bacterial    05120 Epithelial cell signaling in Helicobacter pylori infection     1445 (CSK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     1445 (CSK)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     1445 (CSK) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      1445 (CSK) Protein kinases [BR:hsa01001]  Non-receptor tyrosine kinases   CSK family    1445 (CSK) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    1445 (CSK) SSDB Motif Pfam:  Pkinase_Tyr Pkinase SH2 SH3_1 SH3_9 SH3_2 APH SH3_3 Other DBs NCBI-GeneID:  1445 NCBI-ProteinID:  NP_001120662 OMIM:  124095 HGNC:  2444 Ensembl:  ENSG00000103653 Vega:  OTTHUMG00000142814 Pharos:  P41240(Tchem) UniProt:  P41240 B2R6Q4 A8K3B6 LinkDB Structure PDB:  3EAZ 3EAC 1BYG 1CSK 3D7T 3D7U Position 15q24.1 AA seq 450 aa MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGII PANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV SCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQ DEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVM TQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCE AMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALRE KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMK NCWHLDAAMRPSFLQLREQLEHIKTHELHL NT seq 1353 nt   +upstreamnt  +downstreamnt atgtcagcaatacaggccgcctggccatccggtacagaatgtattgccaagtacaacttc cacggcactgccgagcaggacctgcccttctgcaaaggagacgtgctcaccattgtggcc gtcaccaaggaccccaactggtacaaagccaaaaacaaggtgggccgtgagggcatcatc ccagccaactacgtccagaagcgggagggcgtgaaggcgggtaccaaactcagcctcatg ccttggttccacggcaagatcacacgggagcaggctgagcggcttctgtacccgccggag acaggcctgttcctggtgcgggagagcaccaactaccccggagactacacgctgtgcgtg agctgcgacggcaaggtggagcactaccgcatcatgtaccatgccagcaagctcagcatc gacgaggaggtgtactttgagaacctcatgcagctggtggagcactacacctcagacgca gatggactctgtacgcgcctcattaaaccaaaggtcatggagggcacagtggcggcccag gatgagttctaccgcagcggctgggccctgaacatgaaggagctgaagctgctgcagacc atcgggaagggggagttcggagacgtgatgctgggcgattaccgagggaacaaagtcgcc gtcaagtgcattaagaacgacgccactgcccaggccttcctggctgaagcctcagtcatg acgcaactgcggcatagcaacctggtgcagctcctgggcgtgatcgtggaggagaagggc gggctctacatcgtcactgagtacatggccaaggggagccttgtggactacctgcggtct aggggtcggtcagtgctgggcggagactgtctcctcaagttctcgctagatgtctgcgag gccatggaatacctggagggcaacaatttcgtgcatcgagacctggctgcccgcaatgtg ctggtgtctgaggacaacgtggccaaggtcagcgactttggtctcaccaaggaggcgtcc agcacccaggacacgggcaagctgccagtcaagtggacagcccctgaggccctgagagag aagaaattctccactaagtctgacgtgtggagtttcggaatccttctctgggaaatctac tcctttgggcgagtgccttatccaagaattcccctgaaggacgtcgtccctcgggtggag aagggctacaagatggatgcccccgacggctgcccgcccgcagtctatgaagtcatgaag aactgctggcacctggacgccgccatgcggccctccttcctacagctccgagagcagctt gagcacatcaaaacccacgagctgcacctgtga

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