KEGG T01001: 200186

Homo sapiens (human): 200186

Entry

200186 CDS T01001

Gene name

CRTC2, TORC-2, TORC2

Definition

(RefSeq) CREB regulated transcription coactivator 2

K16333

CREB-regulated transcription coactivator 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04151

PI3K-Akt signaling pathway

hsa04152

AMPK signaling pathway

hsa04922

Glucagon signaling pathway

hsa04931

Insulin resistance

hsa05166

Human T-cell leukemia virus 1 infection

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    200186 (CRTC2)
   04152 AMPK signaling pathway
    200186 (CRTC2)
09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    200186 (CRTC2)
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    200186 (CRTC2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    200186 (CRTC2)

SSDB

Motif

Pfam:

TORC_M TORC_C TORC_N

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

Q53ET0(Tbio)

UniProt:

Q53ET0

LinkDB

Structure

PDB:

4HTM

Position

1q21.3

AA seq 693 aa
MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLA
YTRSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRR
YTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVM
NPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSS
RPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPS
LSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQ
PQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPAST
PGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTD
QRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPS
GHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPHTF
NHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFEVSAAGLELGLGLEDELRM
EPLGLEGLNMLSDPCALLPDPAVEESFRSDRLQ

NT seq 2082 nt +upstreamnt +downstreamnt
atggcgacgtcgggggcgaacgggcctggttcggccacggcctcggcttccaatccgcgc
aaatttagtgagaagattgcgctgcagaagcagcgtcaggccgaggagacggcggccttc
gaggaggtgatgatggacatcggctccacccggttacaggcccaaaaactgcgactggca
tacacaaggagctctcattatggtgggtctctgcccaatgttaaccagattggctctggc
ctggccgagttccagagccccctccactcacctttggattcatctcggagcactcggcac
catgggctggtggaacgggtgcagcgagatcctcgaagaatggtgtccccacttcgccga
tacacccgccacattgacagctctccctatagtcctgcctacttatctcctcccccagag
tctagctggcgaaggacgatggcctggggcaatttccctgcagagaaggggcagttgttt
cgactaccatctgcacttaacaggacaagctctgactctgcccttcatacaagtgtgatg
aaccccagtccccaggatacctacccaggccccacacctcccagcatcctgcccagccga
cgtgggggtattctggatggtgaaatggaccccaaagtacctgctattgaggagaacttg
ctagatgacaagcatttgctgaagccatgggatgctaagaagctatcctcatcctcttcc
cgacctcggtcctgtgaagtccctggaattaacatctttccatctcctgaccagcctgcc
aatgtgcctgtcctcccacctgccatgaacacggggggctccctacctgacctcaccaac
ctgcactttcccccaccactgcccacccccctggaccctgaagagacagcctaccctagc
ctgagtgggggcaacagtacctccaatttgacccacaccatgactcacctgggcatcagc
aggggcatgggcctgggcccaggctatgatgcaccaggacttcattcacctctcagccac
ccatccctgcagtcctccctaagcaatcccaacctccaggcttccctgagcagtcctcag
ccccagcttcagggctcccacagccacccctctctgcctgcctcctccttggcccgccat
gtactgcccaccacctccctgggccacccctcactcagtgctccggctctctcctcctcc
tcttcctcctcctccacttcatctcctgttttgggcgccccctcttaccctgcttctacc
cctggggcctccccccaccaccgccgtgtgcccctcagccccctgagtttgctcgcgggc
ccagccgacgccagaaggtcccaacagcagctgcccaaacagttttcgccaacaatgtca
cccaccttgtcttccatcactcagggcgtccccctggataccagtaaactgtccactgac
cagcggttacccccatacccatacagctccccaagtctggttctgcctacccagccccac
accccaaagtctctacagcagccagggctgccctctcagtcttgttcagtgcagtcctca
ggtgggcagcccccaggcaggcagtctcattatgggacaccgtacccacctgggcccagt
gggcatgggcaacagtcttaccaccggccaatgagtgacttcaacctggggaatctggag
cagttcagcatggagagcccatcagccagcctggtgctggatccccctggcttttctgaa
gggcctggatttttagggggtgaggggccaatgggtggcccccaggatccccacaccttc
aaccaccagaacttgacccactgttcccgccatggctcagggcctaacatcatcctcaca
ggggactcctctccaggtttctctaaggagattgcagcagccctggccggagtgcctggc
tttgaggtgtcagcagctggattggagctagggcttgggctagaagatgagctgcgcatg
gagccactgggcctggaagggctaaacatgctgagtgacccctgtgccctgctgcctgat
cctgctgtggaggagtcattccgcagtgaccggctccaatga

Homo sapiens (human): 23373

Entry

23373 CDS T01001

Gene name

CRTC1, MAML2, MECT1, Mam-2, TORC-1, TORC1, WAMTP1

Definition

(RefSeq) CREB regulated transcription coactivator 1

K15309

CREB-regulated transcription coactivator 1

Organism

hsa Homo sapiens (human)

Pathway

hsa05166

Human T-cell leukemia virus 1 infection

Disease

H01508

Salivary gland cancer

Brite

KEGG Orthology (KO) [BR:hsa00001]
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    23373 (CRTC1)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:hsa03029]
    23373 (CRTC1)
Mitochondrial biogenesis [BR:hsa03029]
Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Coactivators
    23373 (CRTC1)

SSDB

Motif

Pfam:

TORC_M TORC_C TORC_N

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

Q6UUV9(Tbio)

UniProt:

Q6UUV9

LinkDB

Position

19p13.11

AA seq 634 aa
MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQY
YGGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLS
VDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRV
LLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIFPSADQENTTALIPATH
NTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTP
GSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGS
QQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSS
LPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTL
GSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGS
HGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPLDEL
KIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL

NT seq 1905 nt +upstreamnt +downstreamnt
atggcgacttcgaacaatccgcggaaattcagcgagaagatcgcgctgcacaatcagaag
caggcggaggagacggcggccttcgaggaggtcatgaaggacctgagcctgacgcgggcc
gcgcggctccagctccagaaatcccagtacctgcaactgggccccagccgaggccagtac
tatggcgggtccctgcccaacgtgaaccagatcgggagtggcaccatggacctgcccttc
cagacccccttccaatcctcgggcctggacaccagccggaccacccggcaccatgggctg
gtggacagggtgtaccgggagcgtggccggctcggctccccacaccgccggcccctgtca
gtggacaaacacggacggcaggccgacagctgcccctatggcaccatgtacctctcacca
cccgcggacaccagctggagaaggaccaattctgactccgccctgcaccagagcacaatg
acgcccacgcagccagaatcctttagcagtgggtcccaggacgtgcaccagaaaagagtc
ttactgttaacagtcccaggaatggaagagaccacatcagaggcagacaaaaacctttcc
aagcaagcatgggacaccaagaagacggggtccaggcccaagtcctgtgaggtccccgga
atcaacatcttcccgtctgccgaccaggaaaacactacagccctgatccccgccacccac
aacacaggggggtccctgcccgacctgaccaacatccacttcccctccccgctcccgacc
ccgctggaccccgaggagcccaccttccctgcactgagcagctccagcagcaccggcaac
ctcgcggccaacctgacgcacctgggcatcggtggcgccggccagggaatgagcacacct
ggctcctctccacagcaccgcccagctggcgtcagccccctgtccctgagcacagaggca
aggcgtcagcaggcatcgcccaccctgtccccgctgtcacccatcactcaggctgtagcc
atggacgccctgtctctggagcagcagctgccctacgccttcttcacccaggcgggctcc
cagcagccaccgccgcagccccagcccccgccgcctcctccacccgcgtcccagcagcca
ccacccccgccacccccacaggcgcccgtccgcctgccccctggtggccccctgttgccc
agcgccagcctgactcgtgggccacagccgcccccgcttgcagtcacggtaccgtcctct
ctcccccagtcccccccagagaaccctggccagccatcgatggggatcgacatcgcctcg
gcgccggctctgcagcagtaccgcactagcgccggctccccggccaaccagtctcccacc
tcgccagtctccaatcaaggcttctccccagggagctccccgcaacacacttccaccctg
ggcagcgtgtttggggacgcgtactatgagcagcagatggcggccaggcaggccaatgct
ctgtcccaccagctggagcagttcaacatgatggagaacgccatcagctccagcagcctg
tacagcccgggctccacactcaactactcgcaggcggccatgatgggcctcacgggcagc
cacgggagcctgccggactcgcagcaactgggatacgccagccacagtggcatccccaac
atcatcctcacagtgacaggagagtccccccccagcctctctaaagaactgaccagctct
ctggccggggtcggcgacgtcagcttcgactccgacagccagtttcccctggacgaactc
aagatcgaccccctgaccctcgacggactgcacatgctcaacgaccccgacatggttctg
gccgacccagccaccgaggacaccttccggatggaccgcctgtga

Homo sapiens (human): 64784

Entry

64784 CDS T01001

Gene name

CRTC3, TORC-3, TORC3

Definition

(RefSeq) CREB regulated transcription coactivator 3

K16334

CREB-regulated transcription coactivator 3

Organism

hsa Homo sapiens (human)

Pathway

hsa05166

Human T-cell leukemia virus 1 infection

Brite

KEGG Orthology (KO) [BR:hsa00001]
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    64784 (CRTC3)

SSDB

Motif

Pfam:

TORC_M TORC_C TORC_N

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

Q6UUV7(Tbio)

UniProt:

Q6UUV7 Q8TEF4

LinkDB

Position

15q26.1

AA seq 619 aa
MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG
GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG
SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG
GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR
PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM
SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL
HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT
SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ
SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN
CGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD
SSMGLLDPSVEETFRADRL

NT seq 1860 nt +upstreamnt +downstreamnt
atggccgcctcgccgggctcgggcagcgccaacccgcggaagttcagtgagaagatcgcg
ctgcacacgcagagacaggccgaggagacgcgggccttcgagcagctcatgaccgacctc
accctgtcgcgggttcaatttcagaagcttcagcaactgcgccttacacagtaccatgga
ggatccttaccaaatgtgagccagctgcggagcagtgcgtcagagtttcagccgtcattt
caccaagctgataatgttcggggaacccgccatcacgggctggtggagaggccatccagg
aaccgcttccaccccctccaccgaaggtctggggacaagccagggcgacaatttgatggt
agtgcttttggagccaattattcctcacagcctctggatgagagttggccaaggcagcag
cctccttggaaagacgaaaagcatcctgggttcaggctgacatctgcacttaacaggacc
aattctgattctgctcttcacacgagtgctctgagtaccaagccccaggacccctatgga
ggagggggccagtcggcctggcctgccccatacatgggtttctgtgatggtgagaataat
ggacatggggaagtagcatctttccctggcccattgaaagaagagaatctgttaaatgtt
ccgaagccactgccaaaacaactgtgggagaccaaggagattcagtccctgtcaggacgc
cctcgatcctgtgatgttggaggtggcaatgcttttccacataatggtcaaaacctaggc
ctctcacccttcttggggaccttgaacactggagggtcattgccagatctaaccaacctc
cactactcgacacccctgccagcctccctggacaccaccgaccaccactttggcagtatg
agtgtggggaatagtgtgaacaacatcccagctgctatgacccacctgggtataagaagc
tcctctggtctccagagttctcggagtaacccctccatccaagccacgctcaataagact
gtgctttcctcttccttaaataaccacccacagacatctgttcccaacgcatctgctctt
cacccttcgctccgtctgttttcccttagcaacccatctctttccaccacaaacctgagc
ggcccgtctcggcgtcggcagcctcccgtcagccctctcacgctttctcctggccctgaa
gcacatcaaggtttcagcagacagctgtcttcaaccagcccactggccccatatcctacc
tcccagatggtgtcctcagaccgaagccaactttcctttctgcccacagaagctcaagcc
caggtgtcgccgccacccccttaccctgcaccccaggagctcacccagcccctcctgcag
cagccccgcgcccctgaggcccctgcccagcagccccaggcagcctcctcactgccacag
tcagactttcagcttctcccggcccagggctcatctttgaccaacttcttcccagatgtg
ggttttgaccagcagtccatgaggccaggccctgcctttcctcaacaggtgcctctggtg
caacaaggttcccgagaactgcaggactcttttcatttgagaccaagcccgtattccaac
tgcgggagtctcccgaacaccatcctgccagaagactccagcaccagcctgttcaaagac
ctcaacagtgcgctggcaggcctgcctgaggtcagcctgaacgtggacactccatttcca
ctggaagaggagctgcagattgaacccctgagcctggacggactcaacatgttaagtgac
tccagcatgggcctgctggacccctctgttgaagagacgtttcgagctgacagactgtga

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