Homo sapiens (human): 2027
Entry
2027 CDS
T01001
Gene name
ENO3, GSD13, MSE
Definition
(RefSeq) enolase 3
KO
K01689
enolase [EC:
4.2.1.11
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00010
Glycolysis / Gluconeogenesis
hsa01100
Metabolic pathways
hsa01200
Carbon metabolism
hsa01230
Biosynthesis of amino acids
hsa03018
RNA degradation
hsa04066
HIF-1 signaling pathway
Module
hsa_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
hsa_M00002
Glycolysis, core module involving three-carbon compounds
hsa_M00003
Gluconeogenesis, oxaloacetate => fructose-6P
Network
nt06017
Glycogen metabolism
Element
N00731
Glycolysis
N00733
LDHA deficiency in glycolysis
N00735
ENO3 deficiency in glycolysis
Disease
H00069
Glycogen storage disease
H01762
Muscle glycogen storage disease
H01953
Glycogen storage disease type XIII
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
2027 (ENO3)
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
2027 (ENO3)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
2027 (ENO3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
2027 (ENO3)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
2027 (ENO3)
Enzymes [BR:
hsa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.11 phosphopyruvate hydratase
2027 (ENO3)
Messenger RNA biogenesis [BR:
hsa03019
]
Prokaryotic type
Bacterial mRNA degradation factors
RNA degradosome components
Other RNA degradosome components
2027 (ENO3)
Exosome [BR:
hsa04147
]
Exosomal proteins
Proteins found in most exosomes
2027 (ENO3)
SSDB
Motif
Pfam:
Enolase_C
Enolase_N
MR_MLE_C
MAAL_C
Other DBs
NCBI-GeneID:
2027
NCBI-ProteinID:
NP_001967
OMIM:
131370
HGNC:
3354
Ensembl:
ENSG00000108515
Vega:
OTTHUMG00000099394
Pharos:
P13929
(Tbio)
UniProt:
P13929
LinkDB
Structure
PDB:
2XSX
Position
17p13.2
AA seq
434 aa
MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK
GVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK
AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE
AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV
VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD
WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA
QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK
AIFAGRKFRNPKAK
NT seq
1305 nt
+upstream
nt +downstream
nt
atggccatgcagaaaatctttgcccgggaaatcttggactccaggggcaaccccacggtg
gaggtggacctgcacacggccaagggccgattccgagcagctgtgcccagtggggcttcc
acgggtatctatgaggctctggaactaagagacggagacaaaggccgctacctggggaaa
ggagtcctgaaggctgtggagaacatcaacaatactctgggccctgctctgctgcaaaag
aaactaagcgttgtggatcaagaaaaagttgacaaatttatgattgagctagatgggacc
gagaataagtccaagtttggggccaatgccatcctgggcgtgtccttggccgtgtgtaag
gcgggagcagctgagaagggggtccccctgtaccgccacatcgcagatctcgctgggaac
cctgacctcatactcccagtgccagccttcaatgtgatcaacgggggctcccatgctgga
aacaagctggccatgcaggagttcatgattctgcctgtgggagccagctccttcaaggaa
gccatgcgcattggcgccgaggtctaccaccacctcaagggggtcatcaaggccaagtat
gggaaggatgccaccaatgtgggtgatgaaggtggcttcgcacccaacatcctggagaac
aatgaggccctggagctgctgaagacggccatccaggcggctggttacccagacaaggtg
gtgatcggcatggatgtggcagcatctgagttctatcgcaatgggaagtacgatcttgac
ttcaagtcgcctgatgatcccgcacggcacatcactggggagaagctcggagagctgtat
aagagctttatcaagaactatcctgtggtctccatcgaagacccctttgaccaggatgac
tgggccacttggacctccttcctctcgggggtgaacatccagattgtgggggatgacttg
acagtcaccaaccccaagaggattgcccaggccgttgagaagaaggcctgcaactgtctg
ctgctgaaggtcaaccagatcggctcggtgaccgaatcgatccaggcgtgcaaactggct
cagtctaatggctggggggtgatggtgagccaccgctctggggagactgaggacacattc
attgctgaccttgtggtggggctctgcacaggacagatcaagactggcgccccctgccgc
tcggagcgtctggccaaatacaaccaactcatgaggatcgaggaggctcttggggacaag
gcaatctttgctggacgcaagttccgtaacccgaaggccaagtga
DBGET
integrated database retrieval system
