KEGG   Homo sapiens (human): 2027Help
Entry
2027              CDS       T01001                                 

Gene name
ENO3, GSD13, MSE
Definition
(RefSeq) enolase 3
  KO
K01689  enolase [EC:4.2.1.11]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01230  Biosynthesis of amino acids
hsa03018  RNA degradation
hsa04066  HIF-1 signaling pathway
Module
hsa_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
hsa_M00002  Glycolysis, core module involving three-carbon compounds
hsa_M00003  Gluconeogenesis, oxaloacetate => fructose-6P
Network
nt06017  Glycogen metabolism
  Element
N00731  Glycolysis
N00733  LDHA deficiency in glycolysis
N00735  ENO3 deficiency in glycolysis
Disease
H00069  Glycogen storage disease
H01762  Muscle glycogen storage disease
H01953  Glycogen storage disease type XIII
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    2027 (ENO3)
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    2027 (ENO3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    2027 (ENO3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    2027 (ENO3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2027 (ENO3)
Enzymes [BR:hsa01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.11  phosphopyruvate hydratase
     2027 (ENO3)
Messenger RNA biogenesis [BR:hsa03019]
 Prokaryotic type
  Bacterial mRNA degradation factors
   RNA degradosome components
    Other RNA degradosome components
     2027 (ENO3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   2027 (ENO3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Enolase_C Enolase_N MR_MLE_C MAAL_C
Motif
Other DBs
NCBI-GeneID: 2027
NCBI-ProteinID: NP_001967
OMIM: 131370
HGNC: 3354
Ensembl: ENSG00000108515
Vega: OTTHUMG00000099394
Pharos: P13929(Tbio)
UniProt: P13929
LinkDB All DBs
Structure
PDB: 

Position
17p13.2
AA seq 434 aa AA seqDB search
MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK
GVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK
AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE
AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV
VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD
WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA
QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK
AIFAGRKFRNPKAK
NT seq 1305 nt NT seq  +upstreamnt  +downstreamnt
atggccatgcagaaaatctttgcccgggaaatcttggactccaggggcaaccccacggtg
gaggtggacctgcacacggccaagggccgattccgagcagctgtgcccagtggggcttcc
acgggtatctatgaggctctggaactaagagacggagacaaaggccgctacctggggaaa
ggagtcctgaaggctgtggagaacatcaacaatactctgggccctgctctgctgcaaaag
aaactaagcgttgtggatcaagaaaaagttgacaaatttatgattgagctagatgggacc
gagaataagtccaagtttggggccaatgccatcctgggcgtgtccttggccgtgtgtaag
gcgggagcagctgagaagggggtccccctgtaccgccacatcgcagatctcgctgggaac
cctgacctcatactcccagtgccagccttcaatgtgatcaacgggggctcccatgctgga
aacaagctggccatgcaggagttcatgattctgcctgtgggagccagctccttcaaggaa
gccatgcgcattggcgccgaggtctaccaccacctcaagggggtcatcaaggccaagtat
gggaaggatgccaccaatgtgggtgatgaaggtggcttcgcacccaacatcctggagaac
aatgaggccctggagctgctgaagacggccatccaggcggctggttacccagacaaggtg
gtgatcggcatggatgtggcagcatctgagttctatcgcaatgggaagtacgatcttgac
ttcaagtcgcctgatgatcccgcacggcacatcactggggagaagctcggagagctgtat
aagagctttatcaagaactatcctgtggtctccatcgaagacccctttgaccaggatgac
tgggccacttggacctccttcctctcgggggtgaacatccagattgtgggggatgacttg
acagtcaccaaccccaagaggattgcccaggccgttgagaagaaggcctgcaactgtctg
ctgctgaaggtcaaccagatcggctcggtgaccgaatcgatccaggcgtgcaaactggct
cagtctaatggctggggggtgatggtgagccaccgctctggggagactgaggacacattc
attgctgaccttgtggtggggctctgcacaggacagatcaagactggcgccccctgccgc
tcggagcgtctggccaaatacaaccaactcatgaggatcgaggaggctcttggggacaag
gcaatctttgctggacgcaagttccgtaacccgaaggccaagtga

DBGET integrated database retrieval system