Homo sapiens (human): 23098
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Entry
23098 CDS
T01001
Symbol
SARM1, HsTIR, MyD88-5, SAMD2, SARM, hSARM1
Name
(RefSeq) sterile alpha and TIR motif containing 1
KO
K27536
NAD(+) hydrolase SARM1 [EC:
3.2.2.6
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00760
Nicotinate and nicotinamide metabolism
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
23098 (SARM1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.2 Glycosylases
3.2.2 Hydrolysing N-glycosyl compounds
3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
23098 (SARM1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SAM_2
SAM_1
TIR_2
SAM_3
TIR
SAM_PNT
HEAT_2
GHMP_kinases_C
Carb_kinase
DUF4704
Arm
Motif
Other DBs
NCBI-GeneID:
23098
NCBI-ProteinID:
NP_055892
OMIM:
607732
HGNC:
17074
Ensembl:
ENSG00000004139
UniProt:
Q6SZW1
Q05B42
Q0D2N8
Structure
PDB
LinkDB
All DBs
Position
17:28371694..28404049
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AA seq
724 aa
AA seq
DB search
MVLTLLLSAYKLCRFFAMSGPRPGAERLAVPGPDGGGGTGPWWAAGGRGPREVSPGAGTE
VQDALERALPELQQALSALKQAGGARAVGAGLAEVFQLVEEAWLLPAVGREVAQGLCDAI
RLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLAKEREPVEL
ARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALGNCALHGGQA
VQRRMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVERSGTLALVEPLV
ASLDPGRFARCLVDASDTSQGRGPDDLQRLVPLLDSNRLEAQCIGAFYLCAEAAIKSLQG
KTKVFSDIGAIQSLKRLVSYSTNGTKSALAKRALRLLGEEVPRPILPSVPSWKEAEVQTW
LQQIGFSKYCESFREQQVDGDLLLRLTEEELQTDLGMKSGITRKRFFRELTELKTFANYS
TCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIHLGVHRARILT
AAREMLHSPLPCTGGKPSGDTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEA
GKFEDKLIQSVMGARNFVLVLSPGALDKCMQDHDCKDWVHKEIVTALSCGKNIVPIIDGF
EWPEPQVLPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQGRSSRDSSAGSDTSLEGAAP
MGPT
NT seq
2175 nt
NT seq
+upstream
nt +downstream
nt
atggtcctgacgctgcttctctccgcctacaagctgtgtcgcttcttcgccatgtcgggc
ccacggccgggcgccgagcggctggcggtgcctgggccagatgggggcggtggcacgggc
ccatggtgggctgcgggtggccgcgggccccgcgaagtgtcgccgggggcaggcaccgag
gtgcaggacgccctggagcgcgcgctgccggagctgcagcaggccttgtccgcgctgaag
caggcgggcggcgcgcgggccgtgggcgccggcctggccgaggtcttccaactggtggag
gaggcctggctgctgccggccgtgggccgcgaggtagcccagggtctgtgcgacgccatc
cgcctcgatggcggcctcgacctgctgttgcggctgctgcaggcgccggagttggagacg
cgtgtgcaggccgcgcgcctgctggagcagatcctggtggctgagaaccgagaccgcgtg
gcgcgcattgggctgggcgtgatcctgaacctggcgaaggaacgcgaacccgtagagctg
gcgcggagcgtggcaggcatcttggagcacatgttcaagcattcggaggagacatgccag
aggctggtggcggccggcggcctggacgcggtgctgtattggtgccgccgcacggacccc
gcgctgctgcgccactgcgcgctggcgctgggcaactgcgcgctgcacgggggccaggcg
gtgcagcgacgcatggtagagaagcgcgcagccgagtggctcttcccgctcgccttctcc
aaggaggacgagctgcttcggctgcacgcctgcctcgcagtagcggtgttggcgactaac
aaggaggtggagcgcgaggtggagcgctcgggcacgctggcgctcgtggagccgcttgtg
gcctcgctggaccctggccgcttcgcccgctgtctggtggacgccagcgacacaagccag
ggccgcgggcccgacgacctgcagcgcctcgtgccgttgctcgactctaaccgcttggag
gcgcagtgcatcggggctttctacctctgcgccgaggctgccatcaagagcctgcaaggc
aagaccaaggtgttcagcgacatcggcgccatccagagcctgaaacgcctggtttcctac
tctaccaatggcactaagtcggcgctggccaagcgcgcgctgcgcctgctgggcgaggag
gtgccacggcccatcctgccctccgtgcccagctggaaggaggccgaggttcagacgtgg
ctgcagcagatcggtttctccaagtactgcgagagcttccgggagcagcaggtggatggc
gacctgcttctgcggctcacggaggaggaactccagaccgacctgggcatgaaatcgggc
atcacccgcaagaggttctttagggagctcacggagctcaagaccttcgccaactattct
acgtgcgaccgcagcaacctggcggactggctgggcagcctggacccgcgcttccgccag
tacacctacggcctggtcagctgcggcctggaccgctccctgctgcaccgcgtgtctgag
cagcagctgctggaagactgcggcatccacctgggcgtgcaccgcgcccgcatcctcacg
gcggccagagaaatgctacactccccgctgccctgtactggtggcaaacccagtggggac
actccagatgtcttcatcagctaccgccggaactcaggttcccagctggccagtctcctg
aaggtgcacctgcagctgcatggcttcagtgtcttcattgatgtggagaagctggaagca
ggcaagttcgaggacaaactcatccagagtgtcatgggtgcccgcaactttgtgttggtg
ctatcacctggagcactggacaagtgcatgcaagaccatgactgcaaggattgggtgcat
aaggagattgtgactgctttaagctgcggcaagaacattgtgcccatcattgatggcttc
gagtggcctgagccccaggtcctgcctgaggacatgcaggctgtgcttactttcaacggt
atcaagtggtcccacgaataccaggaggccaccattgagaagatcatccgcttcctgcag
ggccgctcctcccgggactcatctgcaggctctgacaccagtttggagggtgctgcaccc
atgggtccaacctaa
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