Homo sapiens (human): 5062 Help Entry 5062              CDS       T01001                                  Gene name PAK2, PAK65, PAKgamma Definition (RefSeq) p21 (RAC1) activated kinase 2   KO K04410   p21-activated kinase 2 [EC:2.7.11.1] Organism hsa  Homo sapiens (human) Pathway hsa04010   MAPK signaling pathway hsa04012   ErbB signaling pathway hsa04014   Ras signaling pathway hsa04360   Axon guidance hsa04510   Focal adhesion hsa04660   T cell receptor signaling pathway hsa04810   Regulation of actin cytoskeleton hsa05130   Pathogenic Escherichia coli infection hsa05170   Human immunodeficiency virus 1 infection hsa05211   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     5062 (PAK2)    04012 ErbB signaling pathway     5062 (PAK2)    04014 Ras signaling pathway     5062 (PAK2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     5062 (PAK2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     5062 (PAK2)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     5062 (PAK2)   09158 Development and regeneration    04360 Axon guidance     5062 (PAK2)  09160 Human Diseases   09162 Cancer: specific types    05211 Renal cell carcinoma     5062 (PAK2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     5062 (PAK2)   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     5062 (PAK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     5062 (PAK2) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      5062 (PAK2) Protein kinases [BR:hsa01001]  Serine/threonine kinases: STE group   STE20 family    5062 (PAK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PBD Kinase-like Pkinase_fungal APH Kdo zinc-ribbons_6 Motif Other DBs NCBI-GeneID:  5062 NCBI-ProteinID:  NP_002568 OMIM:  605022 HGNC:  8591 Ensembl:  ENSG00000180370 Vega:  OTTHUMG00000155534 Pharos:  Q13177(Tchem) UniProt:  Q13177 A8K5M4 LinkDB All DBs Position 3q29 AA seq 524 aa AA seqDB search MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSGT EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAKGTEAPAVVTEEEDDDEETAP PVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIV SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR NT seq 1575 nt NT seq  +upstreamnt  +downstreamnt atgtctgataacggagaactggaagataagcctccagcacctcctgtgcgaatgagcagc accatctttagcactggaggcaaagaccctttgtcagccaatcacagtttgaaacctttg ccctctgttccagaagagaaaaagcccaggcataaaatcatctccatattctcaggcaca gagaaaggaagtaaaaagaaagaaaaggaacggccagaaatttctcctccatctgatttt gagcacaccatccatgttggctttgatgctgttactggagaattcactggcatgccagaa cagtgggctcgattactacagacctccaatatcaccaaactagagcaaaagaagaatcct caggctgtgctggatgtcctaaagttctacgactccaacacagtgaagcagaaatatctg agctttactcctcctgagaaagatggctttccttctggaacaccagcactgaatgccaag ggaacagaagcacccgcagtagtgacagaggaggaggatgatgatgaagagactgctcct cccgttattgccccgcgaccggatcatacgaaatcaatttacacacggtctgtaattgac cctgttcctgcaccagttggtgattcacatgttgatggtgctgccaagtctttagacaaa cagaaaaagaagactaagatgacagatgaagagattatggagaaattaagaactatcgtg agcataggtgaccctaagaaaaaatatacaagatatgaaaaaattggacaaggggcttct ggtacagttttcactgctactgacgttgcactgggacaggaggttgctatcaaacaaatt aatttacagaaacagccaaagaaggaactgatcattaacgagattctggtgatgaaagaa ttgaaaaatcccaacatcgttaactttttggacagttacctggtaggagatgaattgttt gtggtcatggaataccttgctggggggtcactcactgatgtggtaacagaaacgtgcatg gatgaagcacagattgctgctgtatgcagagagtgtttacaggcattggagtttttacat gctaatcaagtgatccacagagacatcaaaagtgacaatgtacttttgggaatggaagga tctgttaagctcactgactttggtttctgtgcccagatcacccctgagcagagcaaacgc agtaccatggtcggaacgccatactggatggcaccagaggtggttacacggaaagcttat ggccctaaagtcgacatatggtctctgggtatcatggctattgagatggtagaaggagag cctccatacctcaatgaaaatcccttgagggccttgtacctaatagcaactaatggaacc ccagaacttcagaatccagagaaactttccccaatatttcgggatttcttaaatcgatgt ttggaaatggatgtggaaaaaaggggttcagccaaagaattattacagcatcctttcctg aaactggccaaaccgttatctagcttgacaccactgatcatggcagctaaagaagcaatg aagagtaaccgttaa

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