Homo sapiens (human): 5062
Entry
5062 CDS
T01001
Gene name
PAK2, PAK65, PAKgamma
Definition
(RefSeq) p21 (RAC1) activated kinase 2
KO
K04410
p21-activated kinase 2 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
hsa04012
ErbB signaling pathway
hsa04014
Ras signaling pathway
hsa04360
Axon guidance
hsa04510
Focal adhesion
hsa04660
T cell receptor signaling pathway
hsa04810
Regulation of actin cytoskeleton
hsa05170
Human immunodeficiency virus 1 infection
hsa05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
5062 (PAK2)
04010 MAPK signaling pathway
5062 (PAK2)
04012 ErbB signaling pathway
5062 (PAK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
5062 (PAK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
5062 (PAK2)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
5062 (PAK2)
09158 Development and regeneration
04360 Axon guidance
5062 (PAK2)
09160 Human Diseases
09162 Cancer: specific types
05211 Renal cell carcinoma
5062 (PAK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
5062 (PAK2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
5062 (PAK2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: STE group
STE20 family
5062 (PAK2)
SSDB
Motif
Pfam:
Pkinase
Pkinase_Tyr
PBD
Kinase-like
Pkinase_fungal
APH
Haspin_kinase
Kdo
Other DBs
NCBI-GeneID:
5062
NCBI-ProteinID:
NP_002568
OMIM:
605022
HGNC:
8591
Ensembl:
ENSG00000180370
Vega:
OTTHUMG00000155534
Pharos:
Q13177
(Tchem)
UniProt:
Q13177
A8K5M4
LinkDB
Position
3q29
AA seq
524 aa
MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSGT
EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP
QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAKGTEAPAVVTEEEDDDEETAP
PVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIV
SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE
LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH
ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC
LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR
NT seq
1575 nt
+upstream
nt +downstream
nt
atgtctgataacggagaactggaagataagcctccagcacctcctgtgcgaatgagcagc
accatctttagcactggaggcaaagaccctttgtcagccaatcacagtttgaaacctttg
ccctctgttccagaagagaaaaagcccaggcataaaatcatctccatattctcaggcaca
gagaaaggaagtaaaaagaaagaaaaggaacggccagaaatttctcctccatctgatttt
gagcacaccatccatgttggctttgatgctgttactggagaattcactggcatgccagaa
cagtgggctcgattactacagacctccaatatcaccaaactagagcaaaagaagaatcct
caggctgtgctggatgtcctaaagttctacgactccaacacagtgaagcagaaatatctg
agctttactcctcctgagaaagatggctttccttctggaacaccagcactgaatgccaag
ggaacagaagcacccgcagtagtgacagaggaggaggatgatgatgaagagactgctcct
cccgttattgccccgcgaccggatcatacgaaatcaatttacacacggtctgtaattgac
cctgttcctgcaccagttggtgattcacatgttgatggtgctgccaagtctttagacaaa
cagaaaaagaagactaagatgacagatgaagagattatggagaaattaagaactatcgtg
agcataggtgaccctaagaaaaaatatacaagatatgaaaaaattggacaaggggcttct
ggtacagttttcactgctactgacgttgcactgggacaggaggttgctatcaaacaaatt
aatttacagaaacagccaaagaaggaactgatcattaacgagattctggtgatgaaagaa
ttgaaaaatcccaacatcgttaactttttggacagttacctggtaggagatgaattgttt
gtggtcatggaataccttgctggggggtcactcactgatgtggtaacagaaacgtgcatg
gatgaagcacagattgctgctgtatgcagagagtgtttacaggcattggagtttttacat
gctaatcaagtgatccacagagacatcaaaagtgacaatgtacttttgggaatggaagga
tctgttaagctcactgactttggtttctgtgcccagatcacccctgagcagagcaaacgc
agtaccatggtcggaacgccatactggatggcaccagaggtggttacacggaaagcttat
ggccctaaagtcgacatatggtctctgggtatcatggctattgagatggtagaaggagag
cctccatacctcaatgaaaatcccttgagggccttgtacctaatagcaactaatggaacc
ccagaacttcagaatccagagaaactttccccaatatttcgggatttcttaaatcgatgt
ttggaaatggatgtggaaaaaaggggttcagccaaagaattattacagcatcctttcctg
aaactggccaaaccgttatctagcttgacaccactgatcatggcagctaaagaagcaatg
aagagtaaccgttaa
DBGET
integrated database retrieval system
