Homo sapiens (human): 6768
Entry
6768 CDS
T01001
Gene name
ST14, ARCI11, HAI, MT-SP1, MTSP1, PRSS14, SNC19, TADG15, TMPRSS14
Definition
(RefSeq) suppression of tumorigenicity 14
KO
K08670
suppressor of tumorigenicity protein 14 [EC:
3.4.21.109
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa05206
MicroRNAs in cancer
Disease
H00734
Autosomal recessive congenital ichthyosis
H00739
Ichthyosis with hypotrichosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
6768 (ST14)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
6768 (ST14)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.109 matriptase
6768 (ST14)
Peptidases and inhibitors [BR:
hsa01002
]
Serine peptidases
Family S1: chymotrypsin family
6768 (ST14)
SSDB
Motif
Pfam:
Trypsin
CUB
Ldl_recept_a
SEA
CUB_2
DUF1986
Other DBs
NCBI-GeneID:
6768
NCBI-ProteinID:
NP_068813
OMIM:
606797
HGNC:
11344
Ensembl:
ENSG00000149418
Vega:
OTTHUMG00000165768
Pharos:
Q9Y5Y6
(Tchem)
UniProt:
Q9Y5Y6
LinkDB
Structure
PDB:
3NCL
3P8G
4IS5
3NPS
4R0I
4O9V
4JZ1
6N4T
4JZI
4JYT
3P8F
4ISO
3SO3
2GV6
3BN9
4O97
2GV7
4ISL
4ISN
5LYO
1EAW
1EAX
Position
11q24.3
AA seq
855 aa
MGSDRARKGGGGPKDFGAGLKYNSRHEKVNGLEEGVEFLPVNNVKKVEKHGPGRWVVLAA
VLIGLLLVLLGIGFLVWHLQYRDVRVQKVFNGYMRITNENFVDAYENSNSTEFVSLASKV
KDALKLLYSGVPFLGPYHKESAVTAFSEGSVIAYYWSEFSIPQHLVEEAERVMAEERVVM
LPPRARSLKSFVVTSVVAFPTDSKTVQRTQDNSCSFGLHARGVELMRFTTPGFPDSPYPA
HARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHALVQLCGTYPPS
YNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQGTFNSPYYPGHY
PPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEINGEKYCGERSQFVVTS
NSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDH
SDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRCSNGKCLSK
SQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEK
DCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYID
DRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKP
AEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLL
PQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYT
RLPLFRDWIKENTGV
NT seq
2568 nt
+upstream
nt +downstream
nt
atggggagcgatcgggcccgcaagggcggagggggcccgaaggacttcggcgcgggactc
aagtacaactcccggcacgagaaagtgaatggcttggaggaaggcgtggagttcctgcca
gtcaacaacgtcaagaaggtggaaaagcatggcccggggcgctgggtggtgctggcagcc
gtgctgatcggcctcctcttggtcttgctggggatcggcttcctggtgtggcatttgcag
taccgggacgtgcgtgtccagaaggtcttcaatggctacatgaggatcacaaatgagaat
tttgtggatgcctacgagaactccaactccactgagtttgtaagcctggccagcaaggtg
aaggacgcgctgaagctgctgtacagcggagtcccattcctgggcccctaccacaaggag
tcggctgtgacggccttcagcgagggcagcgtcatcgcctactactggtctgagttcagc
atcccgcagcacctggtggaggaggccgagcgcgtcatggccgaggagcgcgtagtcatg
ctgcccccgcgggcgcgctccctgaagtcctttgtggtcacctcagtggtggctttcccc
acggactccaaaacagtacagaggacccaggacaacagctgcagctttggcctgcacgcc
cgcggtgtggagctgatgcgcttcaccacgcccggcttccctgacagcccctaccccgct
catgcccgctgccagtgggccctgcggggggacgccgactcagtgctgagcctcaccttc
cgcagctttgaccttgcgtcctgcgacgagcgcggcagcgacctggtgacggtgtacaac
accctgagccccatggagccccacgccctggtgcagttgtgtggcacctaccctccctcc
tacaacctgaccttccactcctcccagaacgtcctgctcatcacactgataaccaacact
gagcggcggcatcccggctttgaggccaccttcttccagctgcctaggatgagcagctgt
ggaggccgcttacgtaaagcccaggggacattcaacagcccctactacccaggccactac
ccacccaacattgactgcacatggaacattgaggtgcccaacaaccagcatgtgaaggtg
cgcttcaaattcttctacctgctggagcccggcgtgcctgcgggcacctgccccaaggac
tacgtggagatcaacggggagaaatactgcggagagaggtcccagttcgtcgtcaccagc
aacagcaacaagatcacagttcgcttccactcagatcagtcctacaccgacaccggcttc
ttagctgaatacctctcctacgactccagtgacccatgcccggggcagttcacgtgccgc
acggggcggtgtatccggaaggagctgcgctgtgatggctgggccgactgcaccgaccac
agcgatgagctcaactgcagttgcgacgccggccaccagttcacgtgcaagaacaagttc
tgcaagcccctcttctgggtctgcgacagtgtgaacgactgcggagacaacagcgacgag
caggggtgcagttgtccggcccagaccttcaggtgttccaatgggaagtgcctctcgaaa
agccagcagtgcaatgggaaggacgactgtggggacgggtccgacgaggcctcctgcccc
aaggtgaacgtcgtcacttgtaccaaacacacctaccgctgcctcaatgggctctgcttg
agcaagggcaaccctgagtgtgacgggaaggaggactgtagcgacggctcagatgagaag
gactgcgactgtgggctgcggtcattcacgagacaggctcgtgttgttgggggcacggat
gcggatgagggcgagtggccctggcaggtaagcctgcatgctctgggccagggccacatc
tgcggtgcttccctcatctctcccaactggctggtctctgccgcacactgctacatcgat
gacagaggattcaggtactcagaccccacgcagtggacggccttcctgggcttgcacgac
cagagccagcgcagcgcccctggggtgcaggagcgcaggctcaagcgcatcatctcccac
cccttcttcaatgacttcaccttcgactatgacatcgcgctgctggagctggagaaaccg
gcagagtacagctccatggtgcggcccatctgcctgccggacgcctcccatgtcttccct
gccggcaaggccatctgggtcacgggctggggacacacccagtatggaggcactggcgcg
ctgatcctgcaaaagggtgagatccgcgtcatcaaccagaccacctgcgagaacctcctg
ccgcagcagatcacgccgcgcatgatgtgcgtgggcttcctcagcggcggcgtggactcc
tgccagggtgattccgggggacccctgtccagcgtggaggcggatgggcggatcttccag
gccggtgtggtgagctggggagacggctgcgctcagaggaacaagccaggcgtgtacaca
aggctccctctgtttcgggactggatcaaagagaacactggggtatag
DBGET
integrated database retrieval system
