KEGG ORTHOLOGY: K27306

ORTHOLOGY: K27306

Entry

K27306                      KO

Symbol

cmrA

Name

mycolic acid reductase

Reaction

R13276

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99983 Lipid metabolism
    K27306  cmrA; mycolic acid reductase

Other DBs

COG:

COG0300

Genes

MTU:

MTV:

MTC:

MRA:

MTF:	TBFG_12531

MTB:	TBMG_01462

MTK:	TBSG_01473

MTZ:	TBXG_001449

MTG:	MRGA327_15475

MTI:	MRGA423_15715

MTE:	CCDC5079_2313

MTUR:

CFBS_2658

MTL:	CCDC5180_2285

MTO:	MTCTRI2_2555

MTD:

UDA_2509

MTN:	ERDMAN_2759

MTJ:	J112_13455

MTUB:

MT7199_2540

MTUC:

J113_17450

MTUE:

J114_13420

MTX:	M943_12955

MTUH:

MTUL:

MTUT:

MTUU:

MTQ:	HKBS1_2656

MBO:	BQ2027_MB2537

MBB:

BCG_2529

MBT:

JTY_2523

MBM:	BCGMEX_2521

MBK:	K60_026070

MBX:

BCGT_2346

MAF:

MAF_25240

MMIC:

RN08_2781

MCE:	MCAN_25481

MCQ:	BN44_50501

MCV:	BN43_40176

MCX:	BN42_40467

MCZ:	BN45_50895

MORY:

MO_002630(cmrA)

MLE:

MLB:

MPA:

MAO:

MAVI:

MAVU:

MAV:

MIT:

MIA:

MID:

MYO:

MCHI:

MIR:

MMAL:

MLP:

MMAN:

MSA:	Mycsm_04403

MUL:

MUL_3788

MMI:

MMAR_3856

MMAE:

MMARE11_37420

MLI:	MULP_04104

MPSE:

MSHO:

MMC:

MKM:

MJL:

MMM:

MKN:	MKAN_05670

MYV:	G155_20240

MYE:	AB431_21115

MHAD:

B586_08560

MDX:	BTO20_11045

MSHG:

MSG_03518

MFJ:	MFLOJ_51750

MSTO:

MSTO_55960

MSIM:

MSIM_41220

MSAK:

MSAS_17910

MKU:	I2456_18530

MLW:	MJO58_19310(cmrA)

MXE:	MYXE_17620

MNV:	MNVI_02250

MPAG:

C0J29_21375

MNM:	MNVM_04900

MGOR:

H0P51_19395

MCOO:

MCOO_15680

MBAI:

MB901379_03424(ydfG)

MSEO:

MSEO_23190

MHEK:

JMUB5695_01845

MGAU:

MGALJ_24790

MLJ:	MLAC_10750

MBRD:

MSHJ:

MMAM:

MSPG:

MOT:	LTS72_05550

MLM:

MLPF_0631

MPAA:

MKK62_08070(cmrA)

MMEH:

M5I08_10905(cmrA)

MKY:	IWGMT90018_19520

MADI:

A7U43_11670

MWU:	PT015_08905(cmrA)

MSM:	MSMEG_4722

MSG:	MSMEI_4605

MSB:	LJ00_23355

MSN:	LI99_23360

MSH:	LI98_23365

MVA:

Mvan_4098

MGI:

Mflv_2545

MSP:	Mspyr1_19740

MCB:	Mycch_3541

MNE:	D174_19755

MYN:	MyAD_19375

MFT:	XA26_41280

MPHL:

MPHLCCUG_03674(ydfG_1)

MVQ:

MYVA_3897

MLL:	B1R94_08670

MRH:	MycrhN_4081

MTHN:

4412656_02967(ydfG)

MHAS:

MHAS_01102(ydfG_1)

MDU:	MDUV_05630

MCHT:

MCHIJ_30190

MDR:	MDOR_26830

MAUU:

NCTC10437_03845(ydfG_2)

MMAG:

MMAD_38490

MMOR:

MMOR_24610

MFX:	MFAL_15590

MAIC:

MAIC_37230

MIJ:	MINS_34500

MALV:

MALV_53900

MTY:	MTOK_61060

MPSC:

MARZ:

MGAD:

MHEV:

MSAR:

MANY:

MAUB:

MPOF:

MPHU:

MMUC:

MMAT:

MBOK:

MFG:	K6L26_11515

MSEI:

MSEDJ_49860

MFLV:

NCTC10271_01627(ydfG_1)

MCEE:

MCEL_01120

MBRM:

L2Z93_002584(cmrA)

MMON:

EWR22_18770

MGO:	AFA91_16905

MHOL:

K3U96_08920

MSEN:

K3U95_09730

MPAE:

K0O64_20660

MRF:	MJO55_18535(cmrA)

MDF:	K0O62_20040

MCRO:

MI149_21240(cmrA)

MGRO:

FZ046_23945

MKR:	MKOR_02720

MPAK:

MIU77_05620(cmrA)

MAB:

MAB_1537c

MMV:	MYCMA_0844

MABB:

MASS_1632

MABL:

MMASJCM_1557

MCHE:

BB28_08355

MIZ:	BAB75_08340

MSTE:

MSTE_01530

MSAO:

MYCSP_06895

MSAL:

DSM43276_01395(isfD2)

MJD:	JDM601_1396

MTER:

4434518_01289(ydfG_3)

MMIN:

MMIN_29630

MHIB:

MHIB_08530

MHER:

K3U94_07640

MVM:	MJO54_07660(cmrA)

CGL:	Cgl2472(Cgl2472)

CGB:

cg2717

CGU:	WA5_2385(CmrA)

CGT:

cgR_2383

CGS:	C624_12155

CGG:	C629_12160

CGM:

cgp_2717

CGJ:

AR0_11875

CGQ:	CGLAR1_11730

CGX:	SB89_11535

CEF:

CE2369

CDI:

DIP1812

CDP:	CD241_1741(cmrA)

CDH:	CDB402_1700(cmrA)

CDT:	CDHC01_1744(cmrA)

CDE:	CDHC02_1740(cmrA)

CDR:	CDHC03_1721(cmrA)

CDA:	CDHC04_1716(cmrA)

CDZ:	CD31A_1813(cmrA)

CDB:	CDBH8_1784(cmrA)

CDS:	CDC7B_1793(cmrA)

CDD:	CDCE8392_1707(cmrA)

CDW:	CDPW8_1804(cmrA)

CDV:	CDVA01_1682(cmrA)

CDIP:

ERS451417_01830(cmrA)

CJK:

jk0519

CUR:

cu1392

CUA:	CU7111_1384(cmrA)

CAR:	cauri_2057(cmrA)

CPU:	CPFRC_08220

CPL:	Cp3995_1676

CPG:	CP316_08310

CPP:	CpP54B96_1662

CPK:	CP1002_04925

CPQ:	CPC231_08220

CPX:	CPI19_03300

CPZ:	CpPAT10_1635

COR:	Cp267_1700

COP:	CP31_08535

COD:	Cp106_1592

COS:	Cp4202_1624

COI:	CPCIP5297_08325

COE:	CP258_08325

COU:	CP162_08320

CPSE:

CPTA_00004

CPSU:

CPTB_01522

CPSF:

CPTC_02230

CRD:	CRES_0610(cmrA)

CUL:	CULC22_01789(cmrA)

CUC:	CULC809_01709(cmrA)

CUE:	CULC0102_1849(cmrA)

CUN:	Cul210932_1812

CUQ:	Cul210931_1709

CUZ:	Cul05146_1798

CUJ:	CUL131002_1735

CUS:	CulFRC11_1710

CVA:	CVAR_0796(cmrA)

CHN:	A605_11365

CCN:	H924_10400

CTER:

A606_03390

CMD:	B841_10485

CAZ:	CARG_01660

CFN:	CFAL_03140

CCG:	CCASEI_11210

CVT:	B843_10230

CGY:	CGLY_12080

CAX:	CATYP_08340

CII:	CIMIT_09510

CUV:	CUREI_09085

CDO:	CDOO_10815

CHM:	B842_10395

CSX:	CSING_10660(cmrA)

CMQ:	B840_09960

CKU:	UL82_03250(cmrA)

CCJ:	UL81_09070(cmrA)

CMV:	CMUST_12290

CEI:	CEPID_09895

CTED:

CTEST_10465(cmrA)

CUT:	CUTER_08655

CDX:	CDES_11195

CSP:

WM42_1952

CSTA:

CSTAT_10445

CCJZ:

ccrud_11095

CFK:	CFRA_09410

CPHO:

CPHO_03060

CFC:	CFLV_09895

CGV:	CGLAU_10065

CSTR:

CAQU:

CSPH:

CAMG:

CMIN:

NCTC10288_00506(cmrA)

CPEG:

CPELA_02600(fabG3)

CXE:	FOB82_08590

CEE:	CENDO_08970(fabG4)

CSAN:

E3227_06285

CGK:	CGERO_08410(fabG4)

CRF:	FRC0190_01839

CRL:	NCTC7448_00283(actIII_1)

CCHO:

CCHOA_08850(ydfG)

CPRE:

Csp1_19390(isfD)

CPSO:

CPPEL_02545(fabG3)

CSUR:

N24_2546(cmrA)

CCYS:

SAMEA4530656_0361(fabG_1)

CMAT:

HBA49_03635

CYZ:	C3B44_09360

CKF:	I6I12_03350

CANS:

CLIA:

CPRP:

CGLU:

CUO:	CUROG_02870(sadH1)

CLIZ:

CSIL:

CTUB:

CLUJ:

CQN:	G7Y29_08530

CKW:	CKALI_02815(fabG2)

CCOE:

CETAM_10595(fabG4)

COK:	COCCU_10980(ydfG)

CZO:	IAU67_02500

CORY:

FQV43_07900

CMF:	GWO64_003050

CWK:	IA203_09575

CUW:	LH390_09095

CPOY:

GP475_09580

CACC:

CACC_09440(fabG2)

CFY:	I6L56_11835

CPSL:

KBP54_08735(cmrA)

CHIN:

J5O04_11310

CJH:	CJEDD_09635

CPSP:

L9H27_02465

CHEI:

CHEID_03160

CIHU:

CIHUM_08780(fabG2)

CCOY:

CCOY_09535(fabG3)

CHAD:

CHAD_09730(fabG4)

CFG:	CFREI_10895(ydfG)

CAQM:

CAQUA_02600(isfD)

CCAW:

CCANI_11110(fabG4)

CAUI:

CAURIS_08820(fabG3)

CFAC:

CFAEC_10810(ydfG)

CFOU:

CFOUR_08875(fabG2)

CFEU:

CFELI_11120(fabG2)

CAUS:

CAURIC_03140

CATR:

CATRI_10030(fabG2)

CDUR:

CDUR_10530(dhbA)

CCOU:

CCONF_09220(fabG2)

CHAN:

CHAN_03530(actIII)

CAFE:

CAFEL_08705(fabG2)

CGF:	CGUA_10720(fabG10)

CGOI:

CGOTT_09375(fabG3)

CAPP:

CAPP_09160

CBOV:

CBOVI_07760(ydfG)

CSUE:

QP029_00770(cmrA)

CBRE:

QP027_08850(cmrA)

CPYR:

CYJ47_02755(cmrA)

CRIE:

AK829_00255

BFV:	C628_12015

NFA:

NFA_12890

NFR:	ERS450000_02831(rbtD_2)

NCY:	NOCYR_1289

NBR:	O3I_008055

NSL:	BOX37_06215

NOZ:	DMB37_28820

NAD:	NCTC11293_02162(ydfG_1)

NIE:	KV110_08670

NGP:	LTT66_05110

NSPU:

IFM12276_49940

RHA:	RHA1_ro01416

RER:

RER_38590

REY:

O5Y_17850

REB:	XU06_18045

RQI:	C1M55_19110

ROP:

ROP_11270

ROA:	Pd630_LPD05536

RPY:	Y013_00310

RBY:	CEJ39_10900

RHB:

NY08_343

RAV:	AAT18_10530

RFA:	A3L23_03669(isfD_2)

RHS:	A3Q41_04571(isfD)

RHW:	BFN03_10870

RRZ:	CS378_00255

RHU:	A3Q40_00942(isfD)

RHQ:	IM25_14260

RHOD:

AOT96_29740

RRT:	4535765_01760(ydfG)

RCR:	NCTC10994_01113(ydfG_1)

RTM:	G4H71_02185

RKO:	JWS14_07275

RGO:	KYT97_26470

ROZ:	CBI38_10895

RPSK:

JWS13_38895

RGOR:

NMQ04_07740(cmrA)

RHOP:

D8W71_20240

REQ:

REQ_30640

GPO:	GPOL_c19110

GOQ:	ACH46_07990

GIT:	C6V83_08405

GMG:	NWF22_20135(cmrA)

DIT:	C3V38_11195

DIZ:	CT688_05290

DPC:	A6048_05275

DLU:	A6035_05420

DKN:	NHB83_04990(cmrA)

TOY:	FO059_13155

» show all

Reference

PMID:17308303

Authors

Lea-Smith DJ, Pyke JS, Tull D, McConville MJ, Coppel RL, Crellin PK

Title

The reductase that catalyzes mycolic motif synthesis is required for efficient attachment of mycolic acids to arabinogalactan.

Journal

J Biol Chem 282:11000-8 (2007)
DOI:10.1074/jbc.M608686200

Sequence

[cgl:Cgl2472]

Reference

PMID:18804030

Authors

Bhatt A, Brown AK, Singh A, Minnikin DE, Besra GS

Title

Loss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing beta-oxo-mycolic acid analogs and accumulation of ketones.

Journal

Chem Biol 15:930-9 (2008)
DOI:10.1016/j.chembiol.2008.07.007

Sequence

[msm:MSMEG_4722] [mtu:Rv2509]

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