KEGG ORTHOLOGY: K06704

ORTHOLOGY: K06704

Entry

K06704                      KO

Symbol

ADAM10, CD156c

Name

disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]

Pathway

map04148

Efferocytosis

map04361

Axon regeneration

map05010

Alzheimer disease

map05120

Epithelial cell signaling in Helicobacter pylori infection

Disease

H00056

Alzheimer disease

H02665

Reticulate acropigmentation of Kitamura

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10
09150 Organismal Systems
  09158 Development and regeneration
   04361 Axon regeneration
    K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10
09160 Human Diseases
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.81  ADAM10 endopeptidase
     K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M12: astacin/adamalysin family
   K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10
CD molecules [BR:ko04090]
Proteins
  K06704  CD156c, ADAM10; a disintegrin and metalloproteinase domain 10

Genes

HSA:	102(ADAM10)

PTR:	746942(ADAM10)

PPS:	100979438(ADAM10)

GGO:	101142970(ADAM10)

PON:	100169741(ADAM10)

PPYG:

129013591(ADAM10)

NLE:	100606667(ADAM10)

HMH:	116463538 116463631

SSYN:

129482472(ADAM10)

MCC:	701355(ADAM10)

MCF:	101925715(ADAM10)

MTHB:

126958467

MNI:	105489609(ADAM10)

CSAB:

103245557(ADAM10)

CATY:

105601091(ADAM10)

PANU:

101023521 116275816(ADAM10)

TGE:	112627561(ADAM10)

MLEU:

105541907(ADAM10)

RRO:	104670896(ADAM10)

RBB:	108544959(ADAM10)

TFN:	117070589(ADAM10)

PTEH:

111553697(ADAM10)

CANG:

105510620(ADAM10)

CJC:	100415138(ADAM10)

SBQ:	101041855(ADAM10)

CIMI:

108306813(ADAM10)

ANAN:

105710665(ADAM10)

CSYR:

103249370(ADAM10)

MMUR:

105881392(ADAM10)

LCAT:

123623265(ADAM10)

PCOQ:

105821373(ADAM10)

OGA:	100962332(ADAM10)

MMU:	11487(Adam10)

MCAL:

110302364(Adam10)

MPAH:

110327224(Adam10)

RNO:	29650(Adam10)

MCOC:

116073842(Adam10)

ANU:	117699738(Adam10)

ASYL:

127688848(Adam10)

MUN:	110561143(Adam10)

CGE:	100772891(Adam10)

MAUA:

101831586(Adam10)

PROB:

127231951(Adam10)

PLEU:

114690776(Adam10)

MORG:

121466052(Adam10)

MFOT:

126490574

AAMP:

119809064(Adam10)

NGI:	103737147(Adam10)

HGL:	101698280(Adam10)

CPOC:

100718999(Adam10)

CCAN:

109689747

DORD:

105980955(Adam10)

DSP:	122114386(Adam10)

DMER:

138808956(Adam10)

PLOP:

125340272(Adam10)

NCAR:

124976191

MMMA:

107137608(Adam10)

ITI:	101970693(Adam10)

OCU:

100101614

OPI:	101527689(ADAM10)

TUP:	102467957(ADAM10)

GVR:	103608716(ADAM10)

CFA:	478321(ADAM10)

CLUD:

112675851(ADAM10)

VVP:	112920741(ADAM10)

VLG:	121484395(ADAM10)

NPO:	129506397(ADAM10)

AML:	100476350(ADAM10)

UMR:	103676794(ADAM10)

UAH:	113269679(ADAM10)

UAR:	123785029(ADAM10)

ELK:

111153288

LLV:

125103845

MPUF:

101673179(ADAM10)

MNP:	131999240(ADAM10)

MLK:	131835865(ADAM10)

NVS:	122893415(ADAM10)

ORO:	101380324(ADAM10)

EJU:	114206362(ADAM10)

ZCA:	113909095(ADAM10)

MLX:	118003444(ADAM10)

NSU:	110584026(ADAM10)

LWW:	102736978(ADAM10)

FCA:	101087998(ADAM10)

PYU:	121041772(ADAM10)

PCOO:

112855202(ADAM10)

PBG:	122468583(ADAM10)

PVIV:

125167886(ADAM10)

LRUF:

124508550

LGF:	123582947(ADAM10)

AJU:

106973789

PTG:	102950285(ADAM10)

PPAD:

109262917(ADAM10)

PUC:

125910047

PLEZ:

122221979(ADAM10)

HHV:	120230860(ADAM10)

BTA:	282132(ADAM10)

BOM:	102285401(ADAM10)

BIU:	109564357(ADAM10)

BBUB:

102390753(ADAM10)

BBIS:

104986299(ADAM10)

CHX:	102172903(ADAM10)

OAS:	101116733(ADAM10)

BTAX:

128054075(ADAM10)

CSUM:

138096382(ADAM10)

ODA:	120853042(ADAM10)

CCAD:

122443550(ADAM10)

MREE:

136171537(ADAM10)

OVR:	110130482(ADAM10)

MBEZ:

129563558(ADAM10)

SSC:	397345(ADAM10)

CFR:	102518129(ADAM10)

CBAI:

105080513(ADAM10)

CDK:	105088967(ADAM10)

VPC:	102527501(ADAM10)

BACU:

103011557(ADAM10)

BMUS:

118890218(ADAM10)

LVE:	103071850(ADAM10)

OOR:	101275940(ADAM10)

LALB:

132521320(ADAM10)

GMF:	115864793(ADAM10)

DDP:	132420957(ADAM10)

DLE:	111177664(ADAM10)

PCAD:

102975188(ADAM10)

PSIU:

116748974(ADAM10)

PPHC:

136143575(ADAM10)

NASI:

112410577(ADAM10)

ECB:	100068314(ADAM10)

EPZ:	103552041(ADAM10)

EAI:	106830043(ADAM10)

MYB:	102260183(ADAM10)

MYD:	102754258(ADAM10)

MMYO:

118652779(ADAM10)

MLF:	102442016(ADAM10)

MDT:	132236751(ADAM10)

MYUM:

139014926(ADAM10)

PKL:	118720561(ADAM10)

EFUS:

103287466(ADAM10)

MNA:	107533751(ADAM10)

DRO:	112311976(ADAM10)

SHON:

118992259(ADAM10)

AJM:	119053476(ADAM10)

PDIC:

114493218(ADAM10)

PHAS:

123808151(ADAM10)

MMF:	118636203(ADAM10)

PPAM:

129064211(ADAM10)

HAI:	109390694(ADAM10)

RFQ:	117023543(ADAM10)

PALE:

102895434(ADAM10)

PGIG:

120604587(ADAM10)

PVP:	105294280(ADAM10)

RAY:	107518608(ADAM10)

MJV:	108393396(ADAM10)

TOD:	119238671(ADAM10)

SARA:

101538322(ADAM10)

SFUM:

130038995(ADAM10)

SETR:

126009249(ADAM10)

LAV:	100659084(ADAM10)

TMU:

101350043

ETF:	101639437(ADAM10)

DNM:	101417950(ADAM10)

MDO:	100024929 100027329(ADAM10)

GAS:	123232128 123238019(ADAM10)

SHR:	100913194(ADAM10) 100925760

AFZ:	127538726 127551192

PCW:	110197392 110205292(ADAM10)

TVP:	118828589(ADAM10) 118832264

PBRV:

138160201 138169048(ADAM10)

MLAO:

141500578 141521725(ADAM10)

OAA:	100074755(ADAM10) 114806495

TACU:

119931600(ADAM10) 119949916

GGA:	374113(ADAM10)

PCOC:

116244652(ADAM10)

MGP:

100545069

CJO:	107318510(ADAM10)

TPAI:

128075128(ADAM10)

LMUT:

125698000(ADAM10)

NMEL:

110403587(ADAM10)

APLA:

101794215(ADAM10)

ACYG:

106033621(ADAM10)

CATA:

118251633(ADAM10)

AFUL:

116493283(ADAM10)

TGU:	100219653(ADAM10)

LSR:	110471419(ADAM10)

SCAN:

103816174(ADAM10)

PMOA:

120509226(ADAM10)

OTC:	121343422(ADAM10)

PRUF:

121354390(ADAM10)

ATRC:

139596915(ADAM10)

GFR:	102043060(ADAM10)

FAB:	101811782(ADAM10)

OMA:	130257331(ADAM10)

PHI:	102110765(ADAM10)

PMAJ:

107209233(ADAM10)

CCAE:

111933890(ADAM10)

CCW:	104684038(ADAM10)

CBRC:

103619470(ADAM10)

ACOE:

138116503(ADAM10)

ETL:	114056365(ADAM10)

ZAB:	102073584(ADAM10)

ZLE:	135452289(ADAM10)

ACHL:

103811304(ADAM10)

SVG:	106851801(ADAM10)

MMEA:

130583428(ADAM10)

HRT:	120758699(ADAM10)

SATI:

136367115(ADAM10)

CCIC:

134049157(ADAM10)

FPG:	101910860(ADAM10)

FCH:	102050786(ADAM10)

CCRI:

104167548(ADAM10)

NNT:	104413305(ADAM10)

SHAB:

115613156(ADAM10)

ACUN:

113483904(ADAM10)

TALA:

104367477(ADAM10)

ACHC:

115341169(ADAM10)

HALD:

104317139(ADAM10)

HLE:	104834711(ADAM10)

AGEN:

126043583

HHAR:

128151512(ADAM10)

GCL:

127020453

CSTI:

104550924(ADAM10)

LDI:	104351936(ADAM10)

MNB:	103773044(ADAM10)

DPUB:

104309907(ADAM10)

PPUS:

135182916(ADAM10)

AVIT:

104276603(ADAM10)

BRHI:

104488198(ADAM10)

EGZ:	104130770(ADAM10)

NNI:	104016847(ADAM10)

PCRI:

104023999

PCAO:

104039831(ADAM10)

PADL:

103914880(ADAM10)

AFOR:

103899879(ADAM10)

FGA:	104070317(ADAM10)

GSTE:

104256756(ADAM10)

CBOY:

140655513(ADAM10)

CLV:	102083444(ADAM10)

CNIC:

135992402(ADAM10)

MUI:	104537344(ADAM10)

PGUU:

104458494(ADAM10)

PLET:

104621900(ADAM10)

EHS:	104506529(ADAM10)

CMAC:

104483316(ADAM10)

CUCA:

104056429(ADAM10)

TEO:	104372218(ADAM10)

BREG:

104637805(ADAM10)

OHA:	104330661(ADAM10)

ACAR:

104520833

CPEA:

104386000(ADAM10)

CVF:	104287112(ADAM10)

RTD:	128914891(ADAM10)

CRID:

134520524(ADAM10)

AAM:	106496382(ADAM10)

AROW:

112974729(ADAM10)

NPD:	112952770(ADAM10)

TGT:	104567505(ADAM10)

DNE:	112991137(ADAM10)

SCAM:

104148424(ADAM10)

ASN:	102371205 102371793

AMJ:	102562482 102563250(ADAM10)

CPOO:

109308972(ADAM10) 109320461

GGN:	109288646(ADAM10) 109294893

PSS:	102444574(ADAM10) 102461827

CMY:	102936468 102944138(ADAM10)

CCAY:

125627339 125643537(ADAM10)

DCC:	119848522 119862424(ADAM10)

CPIC:

101948731 101953463

TST:	117868878 117883650(ADAM10)

CABI:

116821168(ADAM10) 116838433

MRV:	120373604(ADAM10) 120391577

ACS:	100553674(adam10)

ASAO:

132762580(ADAM10)

PVT:	110074537(ADAM10) 110079237

SUND:

121932590(ADAM10) 121936559

PBI:	103053091 103062263(ADAM10)

PMUR:

107283154(ADAM10)

CTIG:

120297076 120306557(ADAM10)

TSR:	106542883(ADAM10)

PGUT:

117660950(ADAM10) 117668650

PCAE:

139308369 139324183(ADAM10)

APRI:

131184515(ADAM10) 131188358

PTEX:

113442309(ADAM10)

NSS:	113421602(ADAM10)

VKO:	123027648(ADAM10)

PMUA:

114583918(ADAM10) 114588574

PRAF:

128401348(ADAM10) 128405612

ZVI:	118086073 118093232(ADAM10)

HCG:	128334968(ADAM10) 128343475

GJA:	107107516(ADAM10)

STOW:

125424460(ADAM10)

EMC:	129345312(ADAM10)

XLA:	108706832 108711361 399187(adam10.S)

XTR:	100491788 733451(adam10)

NPR:	108789826(ADAM10) 108796952

RTEM:

120924706 120931382(ADAM10)

ACAT:

141130685 141131487(ADAM10)

BBUF:

120985758(ADAM10) 120989514

BGAR:

122919690 122927656(ADAM10)

DTC:	141049408 141098945(ADAM10)

PWL:	138268010 138283887(ADAM10)

MUO:	115458968(ADAM10) 115480953

GSH:	117348352(ADAM10) 117365650

DRE:	393392(adam10b) 560975(si:ch1073-396h14.1) 566044(adam10a)

SRX:	107706850 107715085 107741424 107750500

SANH:

107653620 107670741 107687609 107700430 107704208

SGH:	107552424 107561888 107574154 107585986 107588113 107595097

CCAR:

109046957(si:ch1073-396h14.1) 109050964 109087040(adam10a) 109113683

CAUA:

113040149 113040165 113042957 113042958 113051523 113051912 113067144 113105935

CGIB:

127947390 127961248 127987059(si:ch1073-396h14.1) 128014654 128016971

PTET:

122327702(si:ch1073-396h14.1) 122330937 122348925(adam10a)

LROH:

127153704(si:ch1073-396h14.1) 127156647 127168228(adam10a)

GRF:	141301259 141331218(adam10a) 141338415

OMC:	131529654(si:ch1073-396h14.1) 131534697 131544062(adam10a)

PPRM:

120474036 120486226(si:ch1073-396h14.1) 120491441(adam10a)

RKG:	130069931(adam10a) 130070840 130089312(si:ch1073-396h14.1)

MAMB:

125246761 125251118(si:ch1073-396h14.1) 125261896(adam10b) 125264716(adam10a)

CIDE:

127494308 127515451 127520833(si:ch1073-396h14.1)

CERY:

137014508 137027684(si:ch1073-396h14.1) 137029833(adam10a)

MASI:

127409612 127436233 127437623 127439042(si:ch1073-396h14.1) 127447476

TROS:

130548346(si:ch1073-396h14.1) 130551632 130554878(adam10a)

TDW:	130413805 130423549(adam10a) 130429637(si:ch1073-396h14.1)

MANU:

129434287 129442798(adam10a) 129452754

PDAB:

135727089 135749325(adam10a) 135768147

IPU:	108259300(adam10a) 108271130(si:ch1073-396h14.1) 108275251

IFU:	128603054(adam10a) 128613918(si:ch1073-396h14.1) 128618398

PHYP:

113530072 113536691 113540838(adam10)

SMEO:

124379666(adam10a) 124391425(si:ch1073-396h14.1) 124392002

TFD:	113636788(adam10a) 113639154 113644300(si:ch1073-396h14.1)

TVC:	132838517(adam10a) 132854365(si:ch1073-396h14.1) 132856603

CGAR:

128507343 128518748(adam10a) 128542679(si:ch1073-396h14.1)

NGRA:

132874962(adam10a) 132881764 132899409(si:ch1073-396h14.1)

TRN:	134303934(adam10a) 134321320 134331836(si:ch1073-396h14.1)

AMEX:

103027184 103041829(si:ch1073-396h14.1) 103043423(adam10a)

CMAO:

118811815 118817577(adam10a) 118819356(si:ch1073-396h14.1)

EEE:	113571849 113574487 113575694(adam10)

CHAR:

105892433 105893023(adam10a) 122132156

SPIL:

134058315(si:ch1073-396h14.1) 134074665 134094499

TRU:	101068415 101072781 101078173(adam10)

TFS:	130521853(adam10a) 130528581(si:ch1073-396h14.1) 130535896

TNG:	GSTEN00017721G001 GSTEN00025611G001 GSTEN00028800G001

LCO:	104924306(adam10) 104931412 109138148

NCC:	104960057(adam10) 104960084

TBEN:

117471295(adam10a) 117491647 117495638(si:ch1073-396h14.1)

CGOB:

115007325 115009702 115025305(adam10)

PGEO:

117445636 117448005 117467957(adam10a)

GACU:

117533264(adam10a) 117538862 117541131(si:ch1073-396h14.1)

EMAC:

134863302(adam10a) 134869801(si:ch1073-396h14.1) 134875897

ELY:	117252642(adam10a) 117253616(si:ch1073-396h14.1) 117262371

EFO:	125887242 125895492(si:ch1073-396h14.1) 125899756(adam10a)

PLEP:

121937813(si:ch1073-396h14.1) 121947514(adam10a) 121950293

SLUC:

116038274 116055227(si:ch1073-396h14.1) 116060685(adam10a)

ECRA:

117949631 117951000(si:ch1073-396h14.1) 117958595(adam10a)

ESP:	116691941(adam10) 116693868 116695127

PFLV:

114560197 114561555 114571794(adam10)

GAT:	120809559 120812703 120824183(si:ch1073-396h14.1) 120831617(adam10a)

PPUG:

119195954 119216355(si:ch1073-396h14.1) 119228370(adam10a)

AFB:	129095060(si:ch1073-396h14.1) 129102437(adam10a) 129108039

CLUM:

117730193(si:ch1073-396h14.1) 117731989 117747927(adam10a)

PSWI:

130192162(adam10a) 130193741(si:ch1073-396h14.1) 130195476

CANA:

137783959(adam10a) 137794663(si:ch1073-396h14.1) 137804009

CVE:	137870095(si:ch1073-396h14.1) 137881169 137887939(adam10a)

MSAM:

119890154(adam10a) 119893471 119900750(si:ch1073-396h14.1)

SCHU:

122874550 122877697(si:ch1073-396h14.1) 122878274(adam10a)

CUD:	121508420(adam10a) 121512543(si:ch1073-396h14.1) 121514982

SPUL:

138587736(adam10a) 138607564 138613077

LMIX:

132963167(si:ch1073-396h14.1) 132972631 132974593(adam10a)

ALAT:

119017915(adam10a) 119023933 119028768(si:ch1073-396h14.1)

ASTR:

137593657 137594341 137597129 137599094(si:ch1073-396h14.1)

MZE:	101468342(adam10) 101469610 101471777

ONL:	100695735 100707598 100710655(adam10)

OAU:	116309232(si:ch1073-396h14.1) 116326736 116334631(adam10a)

OLA:	101155340(adam10) 101159183 101172489

OML:	112150653(si:ch1073-396h14.1) 112152362 112160714(adam10a)

CSAI:

133444111 133458380(si:ch1073-396h14.1) 133462338(adam10a)

XMA:	102230569(adam10) 102232731 102235509

XCO:	114142909(adam10) 114150800 114160272

XHE:	116718526(adam10) 116725567 116735620

PRET:

103462514(adam10) 103463533 103466445

PFOR:

103129915 103155695 103156888

PLAI:

106955286 106958140 106958532

PMEI:

106907089 106919346 106928916

GAF:	122835335 122838502(si:ch1073-396h14.1) 122843708(adam10a)

PPRL:

129359322 129364056(adam10a) 129374594(si:ch1073-396h14.1)

CVG:	107087405 107095645(adam10) 107097307

CTUL:

119775039 119780852(si:ch1073-396h14.1) 119795460(adam10a)

GMU:	124866912(adam10a) 124873924(si:ch1073-396h14.1) 124880736

NFU:	107381374(adam10) 107388626 107393171

KMR:	108230196 108230826(si:ch1073-396h14.1) 108251752(adam10a)

ALIM:

106521566 106526819 106531660(adam10)

NWH:	119407429(si:ch1073-396h14.1) 119416346 119422316(adam10a)

AOCE:

111577572(adam10a) 111577716 111586567(si:ch1073-396h14.1)

EJA:	138198780 138205743 138212959(adam10a)

BFRE:

138618050(adam10a) 138621177 138626502

MCEP:

125005094(adam10a) 125008901 125014792

CSEM:

103378728(adam10) 103380473 103397216

POV:	109624447 109625416 109636872(adam10)

SSEN:

122760920 122761376 122780907(si:ch1073-396h14.1)

SSOE:

131459417(adam10a) 131466257(si:ch1073-396h14.1) 131470388

HHIP:

117756608(adam10a) 117760656(si:ch1073-396h14.1) 117763808

HSP:	118106022(adam10a) 118109680 118121612(si:ch1073-396h14.1)

PPLT:

128441620(adam10a) 128444987 128448180(si:ch1073-396h14.1)

SMAU:

118302927(adam10a) 118314718 118318520(si:ch1073-396h14.1)

LCF:	108876711 108881395(si:ch1073-396h14.1) 108887706(adam10a)

SDU:	111221439(adam10) 111229691 111232234

SLAL:

111654257 111655135(adam10) 111666982

XGL:	120789059(adam10a) 120790937(si:ch1073-396h14.1) 120793207

HCQ:	109507576 109525931(adam10) 109532053

SSCV:

125967675(adam10a) 125970101 125973800(si:ch1073-396h14.1)

SBIA:

133497851(adam10a) 133502181 133503448(si:ch1073-396h14.1)

PEE:	133399245(adam10a) 133402433 133406220(si:ch1073-396h14.1)

PTAO:

133468637(adam10a) 133478558 133481407(si:ch1073-396h14.1)

BPEC:

110160182 110169553 110175225(adam10)

ENY:	140349576 140354459 140380684(adam10a)

MALB:

109963286(adam10) 109967440 109973882

BSPL:

114852731(adam10a) 114853516(si:ch1073-396h14.1) 114857455

SJO:	128359316 128360136(adam10a) 128362031(si:ch1073-396h14.1)

SSCO:

133981414 133983381(adam10a) 133985371(si:ch1073-396h14.1)

GMH:	115550437 115559067(adam10)

SASA:

106561772 106561774 106562201(adam10) 106573543 106584732 106587342

STRU:

115151751 115167240 115192885 115197708 115203098

OTW:	112219062 112249184 112252197(si:ch1073-396h14.1) 112263716(adam10a) 112265333

OMY:	110501717(si:ch1073-396h14.1) 110502564 110521213 110526414(adam10a) 118944511

OGO:	123998865(si:ch1073-396h14.1) 124031711 124033743 124035726 124037494

ONE:	115109210 115112270 115113653 115124074 115144664

OKI:	109876107 109887842 109888613 109895382 109897681

OKE:	118359506(adam10a) 118373228 118375110(si:ch1073-396h14.1) 118377547 118393877

OMM:	135524589(si:ch1073-396h14.1) 135549149 135559046

OCLA:

139376479 139377194 139385246 139406353 139411473

SALP:

111952855 111969384 111973806 112068468

SNH:	120025369 120036120 120047253 120052330 120053169(si:ch1073-396h14.1) 120066766

CCLU:

121540691 121558909 121568068 121576809 123485820

ELS:	105011472 105016508(adam10) 105018354

OEP:	134010967(si:ch1073-396h14.1) 134021615 134028493(adam10a)

SFM:	108919823 108926731(adam10) 108931162

PKI:	111845001 111846754 111860388

AANG:

118215630 118225832(si:ch1073-396h14.1) 118227666

AROT:

135242387 135252949(si:ch1073-396h14.1) 135255343

CCOG:

133110979 133125961(si:ch1073-396h14.1) 133130444

LOC:	102689715(adam10) 102693175

PSPA:

121294484 121299163 121300696(si:ch1073-396h14.1)

ARUT:

117401274 117429900 117963203(adam10a) 117966367

PSEX:

120537804(si:ch1073-396h14.1) 120539900(adam10a)

LCM:	102349523 102351415(ADAM10)

CMK:	103183500(si:ch1073-396h14.1) 103189371(adam10a)

RTP:	109936297(adam10a)

CPLA:

122541013(adam10a)

HOC:	132828850 132834284(adam10a)

LERI:

129711215(si:ch1073-396h14.1) 129712636(adam10a)

HAKA:

140718777(adam10a) 140740048

PMRN:

116937372 116950624 116953601 116954876

LRJ:	133341406 133346567 133354180 133355124

BFO:	118411340 118411919 118412071 118412678

BBEL:

109468335 109468471 109468715 109468796

CIN:

100184040

SCLV:

120336775

SPU:	115918272 115919534 581388 755122

AJJ:	139966998 139967038

APLC:

110979325 110989644 110989645

ARUN:

117288092 117288282 117288283

AAMU:

139937144 139937357 139937616

AFIL:

140142312 140154376 140154383

AJC:	117101974 117101975

SKO:	100313545(Adam10) 100366937 100367090 100367238 102807735

PFLL:

139116869 139117200 139117389 139117509

DME:	Dmel_CG1964(Kul) Dmel_CG7147(kuz)

DER:	6540795 6554538

DSE:	6612731 6617895

DSI:	Dsimw501_GD15481(Dsim_GD15481) Dsimw501_GD21457(Dsim_GD21457)

DYA:	Dyak_GE18670 Dyak_GE23876

DAN:	6505589 6506009

DSR:	110185137 110189010

DPO:	4800507 4818148

DPE:	6593486 6595137

DMN:	108156102 108162207

DWI:	6644248 6647620

DGR:	6567184 6569582

DMO:	Dmoj_GI10418 Dmoj_GI17667

DAZ:	108611405 108616110

DNV:	108659131 115563697

DHE:	111592702 111600434

DVI:	6632222(Kul) 6634065(kuz)

CCAT:

101455868

BOD:

106622771

BDR:	105225682 105229909

RZE:	108361935 108372162 108372853 108375029 108381691

AOQ:	129248701 129252921

ALUD:

128854922 128864712

TDA:	119663047 119667420 119676898 119687179

MDE:	101888784 101900641 131801326

SCAC:

106082815 106089926

LCQ:	111687946 111690479

LSQ:

119609134

CVJ:	135948728(Kul) 135952459(kuz)

GFS:	119633549 119634712

ECOE:

129940919 129942202

CLON:

129606026 129612138

HIS:	119650694 119650921

AGA:	1273746 1275648

ACOZ:

120948706 120955312 120960899

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:	5565610 5575585

AALB:

109410817 109621728 115256260

ASUA:

134202255 134213552 134225837

CQU:	CpipJ_CPIJ016694 CpipJ_CPIJ017248

CPII:

120421296 120424630

CBRI:

134832234 134833659

CNS:	116341542 116345620

BCOO:

119070042 119071547

LLL:	129790529 129797822

PPAP:

129798494 129807335

AME:	409611 409692 410609

ACER:

107994235 108000950 108001185

ALAB:

122712815 122712908 122719607

ADR:	102670923 102672303 102681224

AFLR:

100866886 100868097 100869852

BIM:	100743906 100745330 100746737

BBIF:

117208929 117209893 117216802

BVK:	117230491 117230827 117235321

BVAN:

117160523 117164369 117166445

BHUN:

126869964 126870411 126873697

BTER:

100649309 100650342 100651761

BAFF:

126923951 126924012 126924928

BPYO:

122570335 122575365 122575766

BPAS:

132911599 132911682 132913931

FVI:	122528408 122532762 122536336

CCAL:

108626630 108628261 108630835

OBB:	114874433 114876424 114883107

OLG:	117603982 117604167 117605030

MGEN:

117222094 117223028 117225172

NMEA:

116429251 116429544 116431352

CGIG:

122396188 122401744 122405321

SOC:	105193142 105201458

MPHA:

105833729 105837793

AEC:	105153222 105154964

ACEP:

105622013 105626161

ACOC:

108689112 108694876

MZT:	108726119(kuz) 108729140

CCOA:

108772314 108779675

PBAR:

105429073 105430103

VEM:	105559899 105565273

COBS:

139109092 139110303(Kuz)

TLN:	139813792(Kuz)

HST:	105184009 105191448

DQU:	106741621 106751921

CFO:	105248456 105253828

FEX:	115234608 115237314

PMEC:

138934462 138944942(Kuz)

LHU:	105671140(Kul) 105675974(kuz)

PGC:	109855381 109863846

OBO:	105281663 105284419

PCF:	106784078 106784802 106790186

PFUC:

122513965 122521467 122523545

VPS:	122627349 122629531 122633897

VCRB:

124423844 124424596 124429252

VVE:	124946418 124949768 124953299

NVI:	100117425 100120688

CSOL:

105365278 105367405

TPRE:

106651781 106657105

LHT:	122499656 122510570

LBD:	127283644 127289616

MDL:	103571724 103580624 103581013

CGLO:

123262848 123264729 123271459

CTYP:

141524585(Kuz) 141533310 141537607

FAS:	105267024 105267045 105273108

DAM:	107035459 107038309 107040618

AGIF:

122850084 122854975 122858939

CINS:

118065975 118067286 118072453

VCAN:

122405799 122409035 122419042

CCIN:

107263166 107264542 107268185

DSM:	124408055 124408149

NPT:	124214662 124215857 124216333(kuz)

NFB:	124177744 124179718 124179772

NLO:	107225363 107225787 107228052

NVG:	124301176 124301738 124302293

AROA:

105683634 105688474 105692011

TCA:	659820 661872

TMOL:

138135551(Kul) 138136515(kuz)

DPA:	109536145 109543348 109546236

ESIM:

136408701 136409186 136410606(kuz)

EFOR:

136343175 136345346 136345558(kuz)

SOY:	115874612 115874613 115882775 115884798 115887382 115887387

AGRG:

126733859 126738665 126747994

ATD:	109594866 109608669

CSET:

123308802 123315573

HAXR:

123676676 123681162

AGB:	108903817 108906840

LDC:	111505843 111507221 111507902

DVV:	114328012 114330043

NVL:	108562925 108565817

APLN:

108734318 108734964

PPYR:

116164872 116167113 116167115

OTU:	111413356 111420464 111424671

BMOR:

101745975 101747087 110385458

BMAN:

114239703 114242067 114245089

MSEX:

115447604 115448198 115452805

DPL:	KGM_204534 KGM_208907 KGM_208923

BANY:

112043461 112053037 112054680

MJU:	123865156 123867426 123867893

NIQ:	126769091 126769262

VCD:	124532237 124532620 124540248

MCIX:

123655116 123655262

PMAC:

106720588 106720604

PPOT:

106103498 106111711

PXU:	106115840 106115996

BPHI:

137925682 137931527 137931881(kuz)

PRAP:

110995185 110995601 111002035

PBX:	123710041 123720451

PNAP:

125063227 125063752

ZCE:	119837157 119840388 119840581

CCRC:

123692979 123693453

LSIN:

126968374 126968604

AAGE:

121726859 121727171

HAW:	110383922 110383939(kuz)

HZE:	124631700 124632072 124641174

TNL:	113494213 113500625 113500765 113500808

SLIU:

111351070 111355438 111355647

OFU:	114353679 114361841 114366719

ONU:	135073794 135074145

ATRA:

106135813 106142849 106142860

GMW:	113515382 113515680

PXY:

105393130

PGW:	126369364 126369451 126376521 126381587

LGLY:

125238086 125242058 125242533 125242569

CSTB:

134743505 134743671

CFUM:

141427314 141427352(kuz) 141441701

CFEL:

113372655 113373467 113373521

CCRN:

123292762 123301277 123305777

API:	100163716 100166223

DNX:	107165629 107172187

AGS:	114130150 114132195

RMD:	113549234 113551419

ACOO:

126833894 126847541

DVT:	126894393 126906516

BTAB:

109032598 109034688

DCI:	103513829 103518111

CLEC:

106663669 106669688

HHAL:

106683289 106686740(kuz)

NLU:	111044216 111054136

HVI:

124369436

MQU:

128997913

PHU:	Phum_PHUM259590 Phum_PHUM259860

FOC:	113201936 113205559

TPAL:

117649610 117649987

ZNE:	110830086 110832133

CSEC:

111862333 111867292

PAME:

138705030(Kul) 138714975(kuz)

SGRE:

126293282 126293640

BROR:

134528432 134535070

IEL:	124159561 124168389

HAMR:

139690264(kuz) 139690492(Kul)

FCD:	110848219 110858640

DPX:	DAPPUDRAFT_310789 DAPPUDRAFT_99915

DMK:	116916909 116932428

DPZ:	124340639 124349396

AFRA:

136031410 136031446

PVM:	113803072(Kul) 113807613(kuz)

PJA:	122248958 122266244

PCHN:

125033622 125040023

PMOO:

119577766 119597465

HAME:

121853479 121863996 121879430

PCLA:

123766772(kuz) 123773138(Kul)

CQD:	128693010(Kul) 128704299(kuz)

PTRU:

123502954 123510302

ESN:	126980258 126996286

MNZ:	135201411 135220906

MRJ:	136832714(Kul) 136849483(kuz)

PORN:

139765712 139767273(kuz)

HAZT:

108671972 108679974

EAF:	111698034 111709038 111712714 111713433

LSM:	121113583 121122187 121131774(kuz) 121131882

TCF:	131887083 131892307

PPOI:

119089849 119111239 119111240 119111242 119111857

ISC:	8024889 8027278 8042795

DSV:	119432845 119448863 119455611 119455860 119456432 119456691 119456715 119456719 119456995 119457614 119462221 119462270 119462273

RSAN:

119375037 119381865 119393090 119393092 119393264 119394647 119394802 119394815 119394848 119394854 119394903 119394905 119394920 119397371

RMP:	119168276 119169701 119171595 119171598 119171781 119172289 119172596 119172734 119172754 119172892 119173739 119184081 119184932 119185859 119187018

VDE:	111245256 111245594 111253857

VJA:	111261476 111262792

GOE:	100898954 100900479 100904463

TUT:	107362658 107369529

DPTE:

113798778 113799663

DFR:	124498357 124500201

PTEP:

107437723 107445643 107448159 107455245

ABRU:

129958943 129972715 129975525 129976095 129981456

UDV:	129219954 129227340 129231158

SDM:	118185997 118186283 118186863 118188832 118200803 118203260

LPOL:

106457004 106457284 106466516 106472701 106477018

PMEO:

129585215

CEL:	CELE_DY3.7(sup-17)

CBR:	CBG_12369(Cbr-sup-17)

CRQ:	GCK72_002527

NAI:	NECAME_03812

BMY:	BM_BM3076(Bma-sup-17)

LOA:	LOAG_00135

TSP:

Tsp_11370

HRO:	HELRODRAFT_113770 HELRODRAFT_191436

LGI:	LOTGIDRAFT_138941 LOTGIDRAFT_235956 LOTGIDRAFT_54048

PVUL:

126815205 126815554 126821586

PCAN:

112555188 112566009 112577167

LSAX:

138950542 138961206

BGT:	106051225 106055443 106059943

GAE:	121369787 121370310 121370363 121372011 121372012 121373320 121373354

HRF:	124115045 124117150 124125978

HRJ:	124253926 124268832 124269537

HASI:

137259289 137260119 137294261

HCRA:

139441700 139460738 139461157

CRG:	105323098 105346452 105346795 109620949 117687376 136269727 136276118

CANU:

128171357 128171999 128172249 128178972

CVN:	111112332 111117423 111117731 111117732 111117733

OED:	125651171 125660929 125660930 125662187

MYI:	110450489 110457318 110465949 110466983

PMAX:

117314957 117315663 117322949 117339763

AIRR:

138305574 138318444

MCAF:

127732558

MMER:

123542283 123542541 123544997 123559793

RPHI:

132713553 132714667 132716161 132731502 132731503 132732396 132732397 132735627 132744168

DPOL:

127849932 127850896 127868181 127869545 127871710

MAEA:

128208335 128222409 128236565 128236978 128238322 128238324 128238327 128241671

OBI:

106879111

OSN:

115219650

LJP:	135462431 135462492 135462717 135468157

LAK:	106151004 106168401 106177601 106177612 106180087

SMM:	Smp_197390

SHX:	MS3_00010597(ADAM10_1)

LLON:

135498561 135498911

NVE:	5501630 5513665 5517822

EPA:	110237622 110248525 110254921

ATEN:

116290581 116291980 116308772

ADF:	107344794 107356551

AMIL:

114949978 114958833 114961861

MCAZ:

138029120 138038407 138042446

MFOO:

137992035 137993697 138007761

PDAM:

113670791 113672703 113683701

SPIS:

111334955 111336097 111340547

DGT:	114519082 114522772 114530322 114530383 114536582

XEN:	124439126 124439129 124439431 124447186 124451092 124452214

HMG:	100208233 100215515

HSY:	130649476 130662768

RES:	135690361 135693095

TAD:	TRIADDRAFT_19172 TRIADDRAFT_19354 TRIADDRAFT_51548 TRIADDRAFT_51549 TRIADDRAFT_52298 TRIADDRAFT_56535 TRIADDRAFT_60597 TRIADDRAFT_62134 TRIADDRAFT_62135

AQU:	100632085 105314001 109584186

MBR:	MONBRDRAFT_29860 MONBRDRAFT_31368

SRE:	PTSG_01510 PTSG_07825 PTSG_10317

» show all

Reference

PMID:9305925

Authors

Rosendahl MS, Ko SC, Long DL, Brewer MT, Rosenzweig B, Hedl E, Anderson L, Pyle SM, Moreland J, Meyers MA, Kohno T, Lyons D, Lichenstein HS

Title

Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases.

Journal

J Biol Chem 272:24588-93 (1997)
DOI:10.1074/jbc.272.39.24588

Sequence

[hsa:102]

Reference

PMID:11477090

Authors

Vincent B, Paitel E, Saftig P, Frobert Y, Hartmann D, De Strooper B, Grassi J, Lopez-Perez E, Checler F

Title

The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein.

Journal

J Biol Chem 276:37743-6 (2001)
DOI:10.1074/jbc.M105677200

Sequence

[hsa:102]

LinkDB

DBGET integrated database retrieval system