KEGG   ORTHOLOGY: K07825
Entry
K07825                      KO                                     
Symbol
GNB3
Name
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Pathway
map04014  Ras signaling pathway
map04062  Chemokine signaling pathway
map04151  PI3K-Akt signaling pathway
map04371  Apelin signaling pathway
map04713  Circadian entrainment
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04727  GABAergic synapse
map04728  Dopaminergic synapse
map04742  Taste transduction
map04926  Relaxin signaling pathway
map05032  Morphine addiction
map05034  Alcoholism
map05163  Human cytomegalovirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05170  Human immunodeficiency virus 1 infection
map05200  Pathways in cancer
Disease
H00787  Congenital stationary night blindness
H01633  High blood pressure
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   04371 Apelin signaling pathway
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   04151 PI3K-Akt signaling pathway
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
  09152 Endocrine system
   04926 Relaxin signaling pathway
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
  09156 Nervous system
   04724 Glutamatergic synapse
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   04727 GABAergic synapse
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   04725 Cholinergic synapse
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   04728 Dopaminergic synapse
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   04726 Serotonergic synapse
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   04723 Retrograde endocannabinoid signaling
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
  09157 Sensory system
   04742 Taste transduction
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
  09159 Environmental adaptation
   04713 Circadian entrainment
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   05163 Human cytomegalovirus infection
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   05167 Kaposi sarcoma-associated herpesvirus infection
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
  09165 Substance dependence
   05032 Morphine addiction
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   05034 Alcoholism
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
   04031 GTP-binding proteins
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
GTP-binding proteins [BR:ko04031]
 Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Genes
HSA: 2784(GNB3)
PTR: 100612078(GNB3)
PPS: 100968267(GNB3)
GGO: 101134530(GNB3)
PON: 100453483(GNB3)
NLE: 100596905(GNB3)
HMH: 116472600(GNB3)
MCC: 713913(GNB3)
MCF: 102125334(GNB3)
MTHB: 126930448
MNI: 105484206(GNB3)
CSAB: 103218476(GNB3)
CATY: 105583036(GNB3)
PANU: 100997846(GNB3)
TGE: 112634141(GNB3)
MLEU: 105541805(GNB3)
RRO: 104680094(GNB3)
RBB: 108542034(GNB3)
TFN: 117090616(GNB3)
PTEH: 111555925(GNB3)
CANG: 105519004(GNB3)
CJC: 100407336(GNB3)
SBQ: 101030203(GNB3)
CIMI: 108295005(GNB3)
CSYR: 103265017(GNB3)
MMUR: 105869000(GNB3)
LCAT: 123640104(GNB3)
PCOQ: 105805044(GNB3)
OGA: 100950950(GNB3)
MMU: 14695(Gnb3)
MCAL: 110295995(Gnb3)
MPAH: 110315943(Gnb3)
RNO: 60449(Gnb3)
MCOC: 116099581(Gnb3)
ANU: 117715413(Gnb3)
MUN: 110548560(Gnb3)
CGE: 100756790(Gnb3)
MAUA: 101842314(Gnb3)
PROB: 127212957(Gnb3)
PLEU: 114708827(Gnb3)
MORG: 121437224(Gnb3)
MFOT: 126514867
AAMP: 119806987(Gnb3)
NGI: 103727502(Gnb3)
HGL: 101718903(Gnb3)
CPOC: 100725705(Gnb3)
CCAN: 109682772(Gnb3)
DORD: 105991079(Gnb3)
MMMA: 107154943(Gnb3)
OCU: 100346625
OPI: 101536793(GNB3)
TUP: 102503265(GNB3)
GVR: 103586407(GNB3)
CFA: 403511(GNB3)
CLUD: 112675357(GNB3)
VVP: 112917330(GNB3)
VLG: 121479877(GNB3)
NPO: 129503454(GNB3)
AML: 100475485(GNB3)
UMR: 103656186(GNB3)
UAH: 113257958(GNB3)
UAR: 123781583(GNB3)
ELK: 111159773
LLV: 125106051
MPUF: 101682835(GNB3)
MNP: 132019915(GNB3)
MLK: 131838470(GNB3)
NVS: 122892610(GNB3)
ORO: 101371845(GNB3)
EJU: 114222462(GNB3)
ZCA: 113921349(GNB3)
MLX: 118025725(GNB3)
NSU: 110581074(GNB3)
LWW: 102732783(GNB3)
FCA: 101084799(GNB3)
PYU: 121021966(GNB3)
PCOO: 112867306(GNB3)
PBG: 122472382(GNB3)
PVIV: 125169798(GNB3)
LRUF: 124502071
PTG: 102953535(GNB3)
PPAD: 109276106(GNB3)
PUC: 125917979 125917990
AJU: 106965344
HHV: 120220432(GNB3)
BTA: 513340(GNB3)
BOM: 102281665(GNB3)
BIU: 109558919(GNB3)
BBUB: 102414827(GNB3)
BBIS: 104992176(GNB3)
CHX: 102169841(GNB3)
OAS: 101110493(GNB3)
BTAX: 128047979(GNB3)
ODA: 120858736(GNB3)
CCAD: 122423970(GNB3)
MBEZ: 129536555(GNB3)
SSC: 100154522(GNB3)
CFR: 102509553(GNB3)
CBAI: 105071086(GNB3)
CDK: 105098202(GNB3)
VPC: 102530911(GNB3)
BACU: 103008105(GNB3)
BMUS: 118901681(GNB3)
LVE: 103089752(GNB3)
OOR: 101286052(GNB3)
DLE: 111176690 111176694(GNB3)
PCAD: 102982318(GNB3)
PSIU: 116760197(GNB3)
NASI: 112391810(GNB3)
ECB: 100052560(GNB3)
EPZ: 103547020(GNB3)
EAI: 106847320(GNB3)
MYB: 102262102(GNB3)
MYD: 102759440(GNB3)
MMYO: 118649724(GNB3)
MLF: 102428334(GNB3)
PKL: 118730180(GNB3)
EFUS: 103289027(GNB3)
MNA: 107544078(GNB3)
DRO: 112321762(GNB3)
SHON: 119002185(GNB3)
AJM: 119060292(GNB3)
PDIC: 114512641(GNB3)
PHAS: 123810635(GNB3)
MMF: 118624402(GNB3)
PPAM: 129071446(GNB3)
HAI: 109373669(GNB3)
RFQ: 117028938(GNB3)
PALE: 102893506(GNB3)
PGIG: 120611665(GNB3)
PVP: 105295952(GNB3)
RAY: 107519797(GNB3)
MJV: 108403551(GNB3)
TOD: 119247771(GNB3)
SARA: 101547419(GNB3)
SETR: 126006589(GNB3)
LAV: 100674807(GNB3)
TMU: 101355136
ETF: 101664254(GNB3)
DNM: 101410636(GNB3)
MDO: 100013759(GNB3)
GAS: 123254622
SHR: 100914745(GNB3)
AFZ: 127539236
PCW: 110213789(GNB3)
OAA: 100090311(GNB3)
PCOC: 116239955(GNB3)
MGP: 100540671(GNB3)
CJO: 107318687(GNB3)
TPAI: 128089888(GNB3)
LMUT: 125685313(GNB3)
NMEL: 110398388(GNB3)
APLA: 101790589(GNB3)
ACYG: 106047856(GNB3)
CATA: 118247633(GNB3)
AFUL: 116496193(GNB3)
TGU: 100228760(GNB3)
LSR: 110480853(GNB3)
SCAN: 103827145(GNB3)
PMOA: 120506424(GNB3)
OTC: 121339246(GNB3)
PRUF: 121351586(GNB3)
GFR: 102041903(GNB3)
FAB: 101810457(GNB3)
OMA: 130248949(GNB3)
PHI: 102112113(GNB3)
PMAJ: 107204110(GNB3)
CCAE: 111938262(GNB3)
CCW: 104687126(GNB3)
CBRC: 103613954(GNB3)
ETL: 114058155(GNB3)
ZAB: 102073295(GNB3)
ACHL: 103797627(GNB3)
SVG: 106857882(GNB3)
MMEA: 130574791(GNB3)
HRT: 120748510(GNB3)
FPG: 101913486(GNB3)
FCH: 102050147(GNB3)
CLV: 102091867(GNB3)
EGZ: 104126600(GNB3)
NNI: 104022493(GNB3)
PCRI: 104028667(GNB3)
PLET: 104624764(GNB3)
EHS: 104509306(GNB3)
PCAO: 104052976(GNB3)
ACUN: 113477022(GNB3)
TALA: 104356921(GNB3)
PADL: 103920938(GNB3)
AFOR: 103905453(GNB3)
ACHC: 115343594(GNB3)
HALD: 104319097(GNB3)
HLE: 104831772(GNB3)
AGEN: 126049050
GCL: 127015798
CCRI: 104160054(GNB3)
CSTI: 104563839(GNB3)
CMAC: 104474088(GNB3)
MUI: 104534050(GNB3)
BREG: 104641456(GNB3)
FGA: 104079484(GNB3)
GSTE: 104257374(GNB3)
LDI: 104350896(GNB3)
OHA: 104327137(GNB3)
NNT: 104400615(GNB3)
SHAB: 115601649(GNB3)
DPUB: 104299450(GNB3)
PGUU: 104459959(GNB3)
ACAR: 104532897(GNB3)
CPEA: 104389531(GNB3)
AVIT: 104268961(GNB3)
CVF: 104292999(GNB3)
RTD: 128904222(GNB3)
CUCA: 104064366(GNB3)
TEO: 104374328(GNB3)
BRHI: 104498148(GNB3)
AAM: 106497266(GNB3)
AROW: 112973015(GNB3)
NPD: 112960115(GNB3)
TGT: 104565679(GNB3)
DNE: 112991063(GNB3)
SCAM: 104150717(GNB3)
AMJ: 106736636(GNB3)
CPOO: 109319390(GNB3)
GGN: 109304605(GNB3)
PSS: 102452897(GNB3)
CMY: 102930298(GNB3)
CCAY: 125622750(GNB3)
DCC: 119853557(GNB3)
CPIC: 101938087(GNB3)
TST: 117885766(GNB3)
CABI: 116837575(GNB3)
MRV: 120401794(GNB3)
ACS: 100564941(gnb3)
ASAO: 132767539(GNB3)
PVT: 110084634(GNB3)
SUND: 121924051(GNB3)
PBI: 103049124(GNB3)
PMUR: 107285810(GNB3)
CTIG: 120306100(GNB3)
PGUT: 117661818(GNB3)
APRI: 131190664(GNB3)
PTEX: 113444489(GNB3)
NSS: 113424514(GNB3)
VKO: 123033196(GNB3)
PMUA: 114587411(GNB3)
PRAF: 128405261(GNB3)
ZVI: 118097709(GNB3)
HCG: 128342829(GNB3)
GJA: 107116804(GNB3)
STOW: 125436787(GNB3)
EMC: 129345373(GNB3)
XLA: 380144(gnb3.L) 380378(gnb3.S)
XTR: 496520(gnb3)
NPR: 108796000(GNB3)
RTEM: 120946605(GNB3)
BBUF: 121005061(GNB3)
BGAR: 122940375(GNB3)
MUO: 115456938(GNB3)
GSH: 117350935(GNB3)
DRE: 406483(gnb3b) 436710(gnb3a)
SRX: 107724639 107727720 107744305 107753988
SANH: 107665150 107666347 107672997 107700194
SGH: 107549492 107549874 107563025 107576905
CCAR: 109048695 109059111 109104354 109111982
CAUA: 113062023 113062433 113116843 113119653 113119881
CGIB: 127935477 127974438 127979172
PTET: 122323924(gnb3b) 122360144(gnb3a)
LROH: 127178659(gnb3a) 127181300(gnb3b)
OMC: 131522305(gnb3a) 131525501(gnb3b)
PPRM: 120484636(gnb3a) 120485655(gnb3b)
RKG: 130090429(gnb3b) 130103673(gnb3a)
MAMB: 125244059(gnb3a) 125275782(gnb3b)
CIDE: 127497554 127501461
MASI: 127421574 127424939 127453365 127453966
TROS: 130558478(gnb3a) 130566792(gnb3b)
TDW: 130416022(gnb3b) 130433506(gnb3a)
MANU: 129447878(gnb3a) 129455248(gnb3b)
IPU: 108266619(gnb3a) 108272554
IFU: 128608098(gnb3a) 128615985(gnb3b)
PHYP: 113535131 113542620(gnb3)
SMEO: 124381817(gnb3b) 124384527(gnb3a)
TFD: 113642712(gnb3a) 113653842(gnb3b)
TVC: 132842255(gnb3b) 132845357(gnb3a)
AMEX: 103042898
CMAO: 118805102(gnb3b) 118814336(gnb3a)
EEE: 113570632 113572607
CHAR: 105892016(gnb3b) 105895148(gnb3a)
TRU: 101069051 101069099
TFS: 130528053 130533009(gnb3a)
TNG: GSTEN00006742G001 GSTEN00015314G001
LCO: 104922229 104935009
NCC: 104946927
TBEN: 117478244(gnb3b) 117494788(gnb3a)
CGOB: 115015676
PGEO: 117440672 117455454(gnb3b)
GACU: 117545371(gnb3b) 117549602(gnb3a)
EMAC: 134861281(gnb3a) 134874497(gnb3b)
ELY: 117262989(gnb3b) 117265296(gnb3a)
EFO: 125893148(gnb3a) 125904675(gnb3b)
PLEP: 121945279(gnb3a) 121958031(gnb3b)
SLUC: 116046416(gnb3b) 116049728(gnb3a)
ECRA: 117946265(gnb3a) 117957083(gnb3b)
ESP: 116691275(gnb3) 116701907
PFLV: 114557513(gnb3) 114568259
GAT: 120810855(gnb3a) 120826998
PPUG: 119197260(gnb3a) 119218995(gnb3b)
AFB: 129096907(gnb3b) 129109558(gnb3a)
CLUM: 117738785(gnb3b) 117745475(gnb3a)
PSWI: 130194278 130213470(gnb3a)
MSAM: 119896328 119897413(gnb3a) 119906976
SCHU: 122864808(gnb3b) 122882067(gnb3a)
CUD: 121513927(gnb3a) 121523274
ALAT: 119006364(gnb3a) 119016911(gnb3b)
MZE: 101464387 101485059(gnb3)
ONL: 100691200 100695768
OAU: 116311895(gnb3b) 116323796(gnb3a)
OLA: 100049496(ol-gb) 101155714(gnb3)
OML: 112143693(gnb3a) 112159608(gnb3b)
CSAI: 133435149(gnb3a) 133460726(gnb3b)
XMA: 102224245 102234508(gnb3)
XCO: 114142261(gnb3) 114155971
XHE: 116717848 116731532
PRET: 103472833 103477980(gnb3)
PFOR: 103136766(gnb3) 103146452
PLAI: 106951139(gnb3) 106952234
PMEI: 106919898 106927928(gnb3)
GAF: 122830984(gnb3a) 122843307(gnb3b)
PPRL: 129371159(gnb3a) 129375944(gnb3b)
CVG: 107082164(gnb3) 107086118
CTUL: 119783155(gnb3a) 119795069(gnb3b)
GMU: 124865298(gnb3a) 124878786(gnb3b)
NFU: 107379476(gnb3) 107394774
KMR: 108235428(gnb3a) 108242690(gnb3b)
ALIM: 106519591 106521057
NWH: 119409348(gnb3a) 119425603(gnb3b)
AOCE: 111569239 111571076
MCEP: 125016963(gnb3a) 125020456(gnb3b)
CSEM: 103388022(gnb3) 103393771
POV: 109633306(gnb3) 109644608
SSEN: 122774970(gnb3a) 122786662(gnb3b)
HHIP: 117771053(gnb3b) 117776817(gnb3a)
HSP: 118113222(gnb3a) 118124643(gnb3b)
SMAU: 118292459(gnb3b) 118315310(gnb3a)
LCF: 108880727(gnb3a) 108887531(gnb3b)
SDU: 111230081(gnb3) 111233212
SLAL: 111665726 111669914(gnb3)
XGL: 120784110(gnb3a) 120786415(gnb3b)
HCQ: 109515382(gnb3) 109528029
SSCV: 125975767 125986866
SBIA: 133500673 133500728(gnb3a)
PEE: 133395414 133401407(gnb3a)
PTAO: 133471536(gnb3b) 133479111(gnb3a)
BPEC: 110162629 110163028(gnb3)
MALB: 109966206 109968899
BSPL: 114842949(gnb3a) 114866149(gnb3b)
SJO: 128365859(gnb3a) 128374697(gnb3b)
SASA: 106570161 106583400 106588420 106605091
STRU: 115173520 115175948 115176477 115177279
OTW: 112223117 112233278 112246596 112265914
OMY: 110488373 110489429 110496204 110517987(gnb3a)
OGO: 123997560 124005948 124012055 124043559
ONE: 115128362 115131637 115141331 115141346
OKI: 109864293 109901493 109903120 109908695
OKE: 118364245 118367320 118397751 118399047
SALP: 111954900 111955480 111965241(gnb3) 111965242
SNH: 120022768 120027450 120031493 120047545
CCLU: 121564969(gnb3a) 121571555 121586434
ELS: 105025847 105028241(gnb3)
SFM: 108922103(gnb3) 108926569
PKI: 111835367(gnb3) 111839731
AANG: 118210269(gnb3a) 118234181
LOC: 102699060(gnb3)
PSPA: 121326288(gnb3a)
ARUT: 117425396(gnb3a)
PSEX: 120535750(gnb3a)
LCM: 102348681(GNB3)
LERI: 129710490
 » show all
Reference
PMID:2107550
  Authors
Levine MA, Smallwood PM, Moen PT Jr, Helman LJ, Ahn TG
  Title
Molecular cloning of beta 3 subunit, a third form of the G protein beta-subunit polypeptide.
  Journal
Proc Natl Acad Sci U S A 87:2329-33 (1990)
DOI:10.1073/pnas.87.6.2329
  Sequence
[hsa:2784]
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