KEGG   Loxodonta africana (African savanna elephant): 100656243
Entry
100656243         CDS       T04351                                 

Gene name
CHRM5
Definition
(RefSeq) muscarinic acetylcholine receptor M5
  KO
K04133  muscarinic acetylcholine receptor M5
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04020  Calcium signaling pathway
lav04080  Neuroactive ligand-receptor interaction
lav04725  Cholinergic synapse
lav04810  Regulation of actin cytoskeleton
lav05010  Alzheimer disease
lav05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    100656243 (CHRM5)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    100656243 (CHRM5)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100656243 (CHRM5)
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    100656243 (CHRM5)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100656243 (CHRM5)
   05022 Pathways of neurodegeneration - multiple diseases
    100656243 (CHRM5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:lav04030]
    100656243 (CHRM5)
G protein-coupled receptors [BR:lav04030]
 Rhodopsin family
  Biogenic amine
   Acetylcholine (muscarinic)
    100656243 (CHRM5)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4 7TM_GPCR_Srbc
Other DBs
NCBI-GeneID: 100656243
NCBI-ProteinID: XP_003418683
UniProt: G3TYL0
LinkDB
Position
Unknown
AA seq 532 aa
MEGESYHNATTVNGTPVNHQPLEHHGLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ
LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN
LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGERTVPP
DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSVSMAEDE
KRKPSHRDLFRSCFNCPRPTLAQKERNQASWSSSRRSTSTTGKPTQPTGLSTDWAKAEQL
TTCSSYPSSEDEDKPTTDPVFQVVYKSQAKESPKEEFSAEETREAFGKAQTEKNDYDTHK
YFLSPAAAHTPKSQKCVAYKFRLVVKADGTQETNNSCRKVKIMPCSFPVSKDSSPKSLDP
NLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLG
YWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
NT seq 1599 nt   +upstreamnt  +downstreamnt
atggaaggggaatcttatcacaatgcaaccactgtcaatggcaccccagtcaatcatcag
cccttggaacaccatggattgtgggaagtcatcaccatagcagctgtaacagctgtggta
agcctgatcaccattgtgggcaatgttttagtcatgatctccttcaaagtcaacagtcag
ctcaagacagttaacaactattacttgctcagcttagcttgtgcagatctcatcataggg
atcttctccatgaacctctatacgacttacatcctcatgggacgctgggccctggggagt
ctggcttgtgatctatggcttgcactggactatgtggccagcaatgcttctgtcatgaac
cttctggtgatcagctttgaccgttacttttccatcacaagacccctgacatatcgggcc
aagcgtactccaaagagagctggcattatgattggtttggcctggctgatctccttcatc
ctctgggccccagcaatcctctgctggcagtacttggttggggagcggacagtaccacca
gatgagtgccagatccaattcctttctgagcccaccatcacttttggtactgccattgct
gccttctacatccctgtttctgtcatgaccatcctctactgccgaatctaccgggaaaca
gagaagcggaccaaggacctggctgacctccagggctctgtctccatggccgaagatgag
aagagaaagccctctcacagggatctgttcaggtcctgcttcaactgccctcggcccacc
ctggcccaaaaggaaaggaaccaggcctcctggtcatcttcccgaagaagcacttccacc
actggaaagccaacccaacccactggcctaagcactgactgggccaaagctgagcagctt
actacctgtagcagctacccctcctcagaggatgaggacaagcccaccactgaccctgtc
ttccaagtggtttacaagagtcaggccaaggaaagcccaaaggaagaattcagtgctgaa
gagaccagggaagcttttgggaaagctcaaactgaaaaaaatgactatgacacccataaa
tacttcctgtctccagctgctgctcatacacccaagagtcagaaatgtgtggcctataaa
ttcagattggtggtaaaagctgatgggacccaggagaccaacaatagctgtagaaaggtg
aaaatcatgccctgctcctttccagtatccaaggactcttcaccgaaaagccttgacccc
aacctcagccatcaaatgactaaacgaaagagaatggtccttgtcaaagagaggaaagca
gctcagaccttgagtgctattcttctagctttcatcatcacatggaccccttataatatc
atggtcctggtctctaccttctgtgacaagtgtgtcccagtcaccctgtggcacttgggc
tactggttgtgctatgtcaacagcactgtcaaccccatctgctatgccctctgcaacaga
accttcaggaagacctttaagatgctgcttctctgccgatggaaaaagaaaaaagtggaa
gagaagttgtattggcaagggaatagcaagctaccatga

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