Loxodonta africana (African savanna elephant): 100659450
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Entry
100659450 CDS
T04351
Gene name
MMP2
Definition
(RefSeq) 72 kDa type IV collagenase
KO
K01398
matrix metalloproteinase-2 (gelatinase A) [EC:
3.4.24.24
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01522
Endocrine resistance
lav04670
Leukocyte transendothelial migration
lav04912
GnRH signaling pathway
lav04915
Estrogen signaling pathway
lav04926
Relaxin signaling pathway
lav04933
AGE-RAGE signaling pathway in diabetic complications
lav05200
Pathways in cancer
lav05205
Proteoglycans in cancer
lav05219
Bladder cancer
lav05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
100659450 (MMP2)
09152 Endocrine system
04912 GnRH signaling pathway
100659450 (MMP2)
04915 Estrogen signaling pathway
100659450 (MMP2)
04926 Relaxin signaling pathway
100659450 (MMP2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100659450 (MMP2)
05205 Proteoglycans in cancer
100659450 (MMP2)
09162 Cancer: specific types
05219 Bladder cancer
100659450 (MMP2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100659450 (MMP2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100659450 (MMP2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100659450 (MMP2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
lav01002
]
100659450 (MMP2)
Enzymes [BR:
lav01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.24 gelatinase A
100659450 (MMP2)
Peptidases and inhibitors [BR:
lav01002
]
Metallo peptidases
Family M10
100659450 (MMP2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Peptidase_M10
fn2
Hemopexin
PG_binding_1
Reprolysin_5
Reprolysin_3
Peptidase_M66
Reprolysin_4
Motif
Other DBs
NCBI-GeneID:
100659450
NCBI-ProteinID:
XP_003416360
LinkDB
All DBs
Position
Unknown
AA seq
661 aa
AA seq
DB search
MMENLGARGALAGALRTLCVLGCLLGHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYG
CPKESCNLFVLKDTLKKMQKFFGLPQTGELDQSTIETMRKPRCGNPDVANYNFFPRKPKW
DKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHG
DGYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLF
GGKEYTSCTDTGRSDGFLWCSTTYNFDKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQG
TSYNSCTTEGRTDGYRWCGTTDDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNK
HESCTSTGRNDGKMWCATTGNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSEDPGA
LMAPIYTYTKNFRLSQDDIKGIQELYGGSPDAGTGTGPTPTLGPVTPEICKQDITFDGVA
QIRGEIFFFKDRFMWRTVTRRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKTVFFAGNE
YWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMD
PGFPKLIADAWNAVPDNLDAVVDLQGGGHSYFFKEAYYLKLENQSLKVVKFGSIKSDWLG
C
NT seq
1986 nt
NT seq
+upstream
nt +downstream
nt
atgatggagaacctaggggcccgaggcgcgcttgccggtgccctgcggacgctctgtgtc
ctaggctgcctgttgggccacgccgccgccgcgccgtcgcccatcatcaagttccccggt
gacgtcgcccccaaaacggacaaagagttggctgtgcaatacctgaacaccttctatggc
tgtcccaaagagagctgcaacctgtttgtgctgaaggacacgctgaagaagatgcagaag
ttctttggactgccccagacaggcgaacttgaccagagcaccattgagaccatgaggaaa
ccacgctgtggcaaccccgatgtagccaactacaacttcttcccccgcaagcccaagtgg
gacaaaaaccagatcacatacaggatcattggctacacacctgatctggaccctgagaca
gtggacgatgccttcgcccgagccttccaagtctggagtgacgtgaccccattgcggttt
tctcgcattcacgatggagaggctgacatcatgatcaactttggccgctgggagcatggc
gatgggtacccatttgacggcaaggacggactcctggcacacgccttcgccccaggccct
ggagttgggggagattcccactttgacgacgatgagctgtggaccctgggagaagggcag
gtggtccgtgtgaagtacgggaacgccgatggagaatactgcaagttcccattcctgttt
ggtggcaaggagtacaccagctgcactgacacgggccgcagtgacggcttcctctggtgt
tccaccacctacaacttcgacaaggacggcaagtacggcttctgtccccacgaagccctg
ttcaccatgggtggcaatgctgacggacagccctgcaagttcccgttccgcttccagggc
acgtcctacaacagctgcaccaccgagggccgcacggatggctaccgctggtgtggtacc
accgacgactacgaccgcgacaagaagtatggcttctgcccagagactgccatgtcaact
gtcggcgggaactcagaaggtgccccatgtgtcttccccttcaccttcctgggcaacaag
cacgagagctgcaccagcaccggacgcaatgacgggaagatgtggtgcgcaaccacgggc
aactacgatgatgaccgcaagtggggcttctgccccgaccaagggtacagcctgttcctc
gtggcagcccacgagtttggccatgcgatggggctggagcactcggaggaccctggagcc
ctgatggcgcccatttacacctacaccaagaacttccgcctgtcccaagatgacatcaag
ggcattcaagagctctatgggggctcccctgacgctggcactggcaccggccccaccccc
acgctgggacccgtcactcccgagatctgcaaacaggacattacctttgatggcgtcgct
cagatccgtggggaaatcttcttcttcaaggaccggttcatgtggcggacagtgacacgg
cgtgacaaacccatgggacccctgttggtggctacgttctggcctgagctcccggagaag
attgacgctgtgtacgaggccccgcaagaggagaagactgtgttttttgcagggaatgag
tactgggtctattcagccagcaccctggagcgcgggtaccccaagcctctgaccagcctg
gggctgccccctgacgtccaacaagtagatgctgcctttaactggagcaagaataagaag
acatacatctttgctggggacaagttctggaggtacaatgaagtgaagaagaaaatggat
cctggcttccccaagctcatcgcagatgcctggaacgctgtccctgataatctggacgcc
gttgtggacctgcagggtggtggtcacagctacttcttcaaggaagcatattacctgaag
ctggaaaaccaaagtttgaaggttgtcaagtttggaagcatcaaatcggactggctgggc
tgctga
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