Loxodonta africana (African savanna elephant): 100668973
Entry
100668973 CDS
T04351
Gene name
ERBB3
Definition
(RefSeq) LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01521
EGFR tyrosine kinase inhibitor resistance
lav04010
MAPK signaling pathway
lav04012
ErbB signaling pathway
lav04020
Calcium signaling pathway
lav04151
PI3K-Akt signaling pathway
lav05205
Proteoglycans in cancer
lav05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100668973 (ERBB3)
04012 ErbB signaling pathway
100668973 (ERBB3)
04020 Calcium signaling pathway
100668973 (ERBB3)
04151 PI3K-Akt signaling pathway
100668973 (ERBB3)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100668973 (ERBB3)
05205 Proteoglycans in cancer
100668973 (ERBB3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100668973 (ERBB3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100668973 (ERBB3)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100668973 (ERBB3)
Protein kinases [BR:
lav01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100668973 (ERBB3)
SSDB
Motif
Pfam:
Pkinase_Tyr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
Kinase-like
Other DBs
NCBI-GeneID:
100668973
NCBI-ProteinID:
XP_003405167
LinkDB
Position
Unknown
AA seq
1343 aa
MRANGALQVLGFLLSLARGSEVGSSQAVCPGTLNGLSVTGDAENQYQTLYKLYNRCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILSGGVYIERNEKLCHMDTIDWRDIVRHQDAEIVVKENG
KSCPPCHEVCKGRCWGPGPEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD
TDCIACRHFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQAS
CVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIEG
RSLYNRGFSLLIMKNLNITSLGLRSLREISAGRIYISANRQLCYHHSLNWTKLLRGPAEE
RLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEP
REFAHEAECFSCHPECEPMEGAATCNGSGSDACAQCAHFRDGPHCVSSCPHGVLGAKGPI
YKYPDVQNECRPCHENCTQGCKGPDLQDCLDQTQVPISKTHLAMALALVVGSLMIFLILG
SSFLYWRGRRIQNKRAMRRYLERGESLEPLDPREKANKVLARIFKETELRKLKVLGSGVF
GTVHKGVWIPEGESIKIPVCIKVIEDKSERQSFQAVTDHMRAIGSLDHAHIVRLLGLCPG
SSLQLVTQYLPLGSLLDYVREHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVT
VWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRESGPGIPPGAEPPALTNKELEEVELEPELDLDLDLEGEED
NLATTLGSALSLPVGTLTRPRGSQSLLSPSSGYMPMNQGNLGEACQESAVGGGSERCPRP
ASLHPMPWRHLTSESSEGHVTGSEAELQEKASMCRSRSRSRSRSPRPCGDSAYHSQRHSL
LTPVTPLSPPGLEEEDINGYVMPDTHLKGTPSSREGTLSSVGLSSVLGTEEDDEDEEYEY
MNRRRKHSPPRPPRPSSLEELGYEYMDLGSDLSASLGSTQSCPLHPVPIMPTAGTTPDED
YEYMNRRRGGGDPGGDYASMGACSAAEQGYEEMRAFRGPGYHAPNVHYTRLKTLRSLEAT
DSAFDNPDYWHSRLFPKTNAQGT
NT seq
4032 nt
+upstream
nt +downstream
nt
atgagggcgaacggggctctgcaggtgctgggcttccttctcagcctggcccggggctcc
gaggtgggcagctcgcaggcagtatgtcccggaactctgaatggcctgagtgtgactggc
gatgccgagaaccaataccagacactgtacaagctctacaataggtgtgaggtggtgatg
gggaaccttgagattgtgctcacaggacacaatgcagatctctcattcttgcagtggatc
cgagaagtgacaggttatgtcctcgtggccatgaatgaattctctacactgccactgccc
aacctgcgagtggtacggggcacccaggtctatgatgggaagtttgccatcttcgtcatg
ttgaactataacaccaactccagccatgctctgcggcagctccgctttactcagctcact
gaaattctgtcagggggtgtttatattgagaggaacgagaaactttgtcacatggacaca
attgactggagggacatcgtgaggcaccaggacgctgaaattgtggtgaaggaaaatggc
aagagctgtcccccctgtcatgaggtctgcaaaggacgatgctggggtccaggaccagaa
gactgccagacattgaccaagaccatctgtgcccctcaatgtaatggtcactgctttggg
ccaaatcccaaccagtgctgccatgatgagtgtgcagggggctgctcaggccctcaagac
acagattgcattgcctgccgacacttcaatgacagtggagcctgtgtacgtcagtgtcca
cagccacttgtctacaacaagctaactttccagctggaacccaatccccacaccaagtat
cagtatggaggagtttgtgtggccagctgtccccataacttcgtggtggatcaagcttct
tgtgtcagggcctgtcctccagacaagatggaggtagataaaaatgggctcaagatgtgc
gagccttgtggggggctgtgtcccaaagcctgtgaggggacgggctctgggagccgcttc
cagactgtggactcgagcaacatcgatggatttgtgaactgcaccaagatcctaggcaac
ctggacttcctcatcactggcctcaatggagacccctggcacaagatacctgccctggac
cctgagaaactcaatgtcttccggacagtacgggagatcaccggttacctaaacatccag
tcctggcctccccacatgcacaacttcagtgtcttttccaacctgacaaccattgagggc
agaagcctctacaaccggggcttctccttgttgatcatgaagaacttgaatatcacatct
ctgggcctccggtccctgagggaaattagtgctgggcgtatctacataagtgccaatcgg
cagctctgctatcaccattctctaaactggaccaagctgcttcgagggcctgcagaagag
agactagacatcaagcataatcggccccgcagagactgtgtggcggagggcaaagtgtgc
gacccactgtgctcctctgggggatgttggggcccaggccctggtcagtgcttatcctgc
cgaaactacagccgaggaggtgtctgcgtgacacactgcaactttctgaatggggagcct
cgtgagtttgcccatgaggctgaatgtttctcctgccacccggaatgcgaacccatggag
ggcgctgccacatgcaatggctcgggctctgatgcttgtgctcagtgtgcccattttcga
gatgggccgcactgtgtgagcagctgccctcatggagtcctaggtgccaagggtcccatc
tacaagtatccggatgttcagaatgaatgccgaccctgtcatgagaactgcacccaaggg
tgtaaaggaccagacctgcaagactgtttagaccaaactcaggtgccgatcagcaaaacc
catctggcaatggctttggcattggtagtaggatcgcttatgattttcctgatcctgggc
agtagttttctctattggcgtgggcgccggatccagaataaaagggccatgaggcgctac
ttggaacggggtgagagtttagagcctctggatcccagagagaaggctaacaaggtcttg
gccagaatcttcaaagagacagagctgaggaagcttaaagtgcttggttcaggcgtcttt
ggaactgtgcacaaaggtgtgtggatccctgagggtgaatccatcaagattccagtctgc
ataaaagtcattgaggacaagagtgaacggcagagttttcaagctgtgacagatcatatg
cgggccattggcagcctagaccacgcccacattgtacggctgctgggactgtgcccaggg
tcatcgctgcagcttgtcacacaatacttgcctctgggttccctgctggattatgtgaga
gaacaccggggggccctggggccacaactgctgcttaactggggagtacaaattgccaag
ggtatgtactaccttgaggagcatggtatggtacataggaacctggccgcccgaaacgtg
ctgctcaagtcacccagtcaagttcaggtggcagattttggggtggctgacctgctgccc
cctgatgataaacagctactacacagtgaggccaagactccaattaagtggatggccctc
gagagcatccactttgggaaatacacgcaccagagtgacgtctggagctatggtgtgaca
gtttgggagctgatgaccttcggggcagagccctatgcagggctgagactggctgaagta
ccagatctgctggagaagggggagcgattggcacagccccagatctgcaccattgatgtc
tacatggtcatggtcaagtgttggatgattgatgagaacattcgccccacctttaaagaa
ctagccaatgagttcaccaggatggcccgtgacccacccaggtatctggtcataaagaga
gagagtgggcctggaatcccccctggggcagagccccctgctctgacaaacaaggaactg
gaggaagtagagctagagccagagctagacctggacctggacttggaaggagaggaggac
aacctggcaaccacactgggttcagccctcagcctgccagttggaacactcactcggcca
cgtggaagccagagtcttctaagtccatcatctggatacatgcccatgaaccagggtaat
cttggggaggcttgccaggaatctgcagtcggtgggggtagtgagcggtgtccccgtcca
gcctccctgcacccaatgccatggcgacacctgacatcagagtcatcggagggccatgtg
acaggctctgaggctgagctccaggagaaggcatcaatgtgtaggagccggagccgaagc
cggagccggagcccacggccatgtggggacagtgcctaccattcccagcgccacagcctg
cttactcctgtcaccccactctccccaccagggctagaggaagaggatatcaatggttat
gtcatgccagatacccaccttaaaggtactccctcctcccgggaaggcaccctttcttca
gtgggtctcagttctgtcctgggtacggaagaagatgatgaagatgaagagtatgaatac
atgaaccggaggagaaagcatagtccacctcgtcctcctaggccaagttccctcgaggag
ctgggttatgagtacatggatttgggatcagacctcagtgcctcccttggcagcacacag
agttgccccctccaccctgtgcctattatgcccactgctggcacaactccagatgaagac
tatgagtatatgaaccgacgacgtggtggaggagatcctgggggggattatgcatccatg
ggggcctgttcggcagctgagcaagggtatgaagagatgagagcttttcgggggcctgga
taccatgcccccaatgtccattatacccgtctcaaaacgctccggagcttagaagccact
gactctgcctttgataaccctgattactggcatagcaggcttttccccaagaccaatgcg
cagggaacataa
DBGET
integrated database retrieval system
