Loxodonta africana (African savanna elephant): 100674758
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Entry
100674758 CDS
T04351
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04014
Ras signaling pathway
lav04072
Phospholipase D signaling pathway
lav04148
Efferocytosis
lav04360
Axon guidance
lav04625
C-type lectin receptor signaling pathway
lav04630
JAK-STAT signaling pathway
lav04650
Natural killer cell mediated cytotoxicity
lav04660
T cell receptor signaling pathway
lav04670
Leukocyte transendothelial migration
lav04722
Neurotrophin signaling pathway
lav04920
Adipocytokine signaling pathway
lav04931
Insulin resistance
lav05168
Herpes simplex virus 1 infection
lav05205
Proteoglycans in cancer
lav05208
Chemical carcinogenesis - reactive oxygen species
lav05211
Renal cell carcinoma
lav05220
Chronic myeloid leukemia
lav05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100674758 (PTPN11)
04630 JAK-STAT signaling pathway
100674758 (PTPN11)
04072 Phospholipase D signaling pathway
100674758 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100674758 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
100674758 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
100674758 (PTPN11)
04660 T cell receptor signaling pathway
100674758 (PTPN11)
04670 Leukocyte transendothelial migration
100674758 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
100674758 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
100674758 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
100674758 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100674758 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
100674758 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100674758 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100674758 (PTPN11)
05211 Renal cell carcinoma
100674758 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
100674758 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100674758 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
lav01009
]
100674758 (PTPN11)
Enzymes [BR:
lav01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
100674758 (PTPN11)
Protein phosphatases and associated proteins [BR:
lav01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
100674758 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
100674758
NCBI-ProteinID:
XP_023395098
LinkDB
All DBs
Position
Unknown
AA seq
597 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFRENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQVLLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPSCTEMREDNARVYENVGLMQQQKSFR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcgaagatggtttcacccaaatatcactggcgtggaggcagaaaacctactg
ttgacaagaggagttgatggcagttttttggcaagacccagtaaaagtaaccctggagac
ttcacactttccgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gattactatgacctgtacggaggggagaagtttgccactttggctgagctggtccagtat
tacatggaacatcacgggcaattgaaagagaagaatggagacgttattgagctcaaatat
cctctgaactgtgcagaccctacctctgaaaggtggtttcatggacacctgtctgggaaa
gaagccgagaaattactgacagagaaaggaaaacacggcagctttcttgtgcgcgagagc
cagagccaccctggagattttgttctctctgtccgcactggagatgacaaaggggagagc
aatgatggcaagtctaaagtgacccacgtcatgattcgctgtcaggaactgaaatatgat
gtcggtggaggagagcggtttgattctttgacagatctcgtggagcattacaagaagaac
cctatggtagaaacattgggcaccgttctacaactcaagcagcccctcaatacaactcgt
atcaatgctgctgagatagaaagccgtgttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagactctgcaacaacaggagtgcaaa
cttctctacagccgcaaagagggccaaaggcaagaaaataaaaacaaaaatagatataaa
aacatcctgccttttgatcacaccagggttgtcctacacgatggcgatcccaacgagcct
gtttcagattatatcaatgcaaatattataatgcctgaatttgaaaccaagtgcaacaat
tcaaaacccaagaagagttacattgccacccaaggctgcctgcaaaacacggtgaacgac
ttctggcggatggtgttccgggagaactcccgagtgattgtcatgacaacgaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgatgagtatgccctcaaagaatat
ggggtcatgcgtgttaggaacgtcaaagaaagtgccgctcatgactataccttaagagaa
cttaaactttcgaaggttgggcaagttctactccagggcaatacggagagaaccgtctgg
caataccactttcggacctggccggaccatggcgtgcccagtgaccccgggggtgtgctg
gacttcttggaggaggtgcaccacaagcaggagagcatcatggatgcggggcctgtggtg
gttcactgcagtgctggaattggccgaacagggacattcattgtgattgatatcctcatt
gacatcatcagagagaaaggcgtcgactgtgacatcgatgttcccaaaaccatccagatg
gtgcggtctcagaggtcagggatggtccagacagaagcacaataccggttcatctatatg
gctgtccagcactatattgaaacactacagcgcaggatcgaagaagaacagaaaagcaag
aggaaagggcatgaatatacaaatattaagtattccctagcggaccagaccagtggagat
cagagtccccttccaccttgtaccccaacaccatcctgtacagaaatgagagaagataat
gccagagtctatgaaaacgtgggtctgatgcagcagcagaaaagtttcagatga
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