KEGG   Manis javanica (Malayan pangolin): 108400067
Entry
108400067         CDS       T06054                                 
Name
(RefSeq) cytochrome P450 11B1, mitochondrial isoform X1
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv00140  Steroid hormone biosynthesis
mjv01100  Metabolic pathways
mjv04927  Cortisol synthesis and secretion
mjv04934  Cushing syndrome
Module
mjv_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    108400067
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    108400067
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    108400067
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:mjv00199]
    108400067
Enzymes [BR:mjv01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     108400067
Cytochrome P450 [BR:mjv00199]
 Cytochrome P450, animal type
  CYP11 family
   108400067
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 108400067
NCBI-ProteinID: XP_017520750
LinkDB
Position
Unknown
AA seq 503 aa
MAFRAKADMRMAGPWLSLCRARALGAGASLVPKAVLPFEAIPQSPGNKWVRVLQVWKDKG
SENFHLDLHRTFQELGPIFRYDVGGPHTVFVMLPEDTEQLQRVESSEPWRTPLYPWLAYR
EHRGHRCGVFLLNGPQWRSDRLQLNPDVLSLQATHKFIPMVDRVARDFCKVLKAKVLQNA
RGSLTLDIQPSIFHYSIEASHYVLYGERLGLLGQGPSAASMGFLHALQAILKSTVQLMFM
PRSLSRWVSSPTWREHFEAWDYVFQYANGAIQRTYQELALSPSQHYSGLLGELLAHAEMS
LEAIRANSVDLTAGSVDTTSYPLLMTLFELARNPTLQQSVRQESLVAEAKISENPQLVLT
ELPLLRAALKETLRLYPVGIFVERRVSSDLVLQNYHVPAGTLVKVCLYSLGRNPSVLARP
ESYHPQRWLNSRAAGSRLMHLAFGFGVRQCLGRRLAEVEMLLFLHHVLKGFLVDTLTQED
VRMIYRYVLMPSSLPLLTFRATS
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggccttcagggcaaaggcggacatgcggatggcagggccctggctgtcgctgtgccgg
gcacgcgcactgggagccggagcttctcttgtccccaaggctgtgctgccctttgaagcc
ataccccagagtcctggcaacaagtgggtgagggtgctgcaggtctggaaggataagggc
tccgagaacttccacctggacttgcatcggaccttccaggagctggggcccattttcagg
tatgacgtgggagggccacacacggtgttcgtgatgctgcccgaggacacggagcagctg
cagcgggtggaaagctctgagccctggaggacacctctgtacccctggctggcctaccga
gagcaccgtgggcacagatgcggcgtgttcctgctaaatgggccccagtggcgctcggac
agactgcagctgaacccagacgtgctgtcactgcaggccacccacaagttcatccccatg
gtggaccgggtggccagggatttctgcaaggtcctgaaggcaaaggtgctgcagaatgcc
cggggaagcctgacccttgacatccagcccagcatcttccactacagcatagaagccagc
cactacgtcctgtatggagagcggctgggcctcctgggccaaggcccgagtgctgccagc
atgggctttctccatgctctgcaggccattttaaaatccaccgtgcagctcatgttcatg
cccaggagcctgtcacgctgggtgagctccccgacatggagagagcactttgaggcctgg
gactacgtcttccagtatgccaacggtgccattcagagaacctatcaggagctggccctc
agcccctcgcagcactacagtggcctcttaggggagcttcttgcgcatgcagagatgagc
ctggaagccatcagggccaactctgtggacctcactgccgggagcgtggacacgacgtcc
taccccttgctgatgaccctgtttgagctggcccggaaccccaccttgcagcagtccgta
cgccaggagagtctggtggccgaggccaagatctctgaaaacccccagttggtcctcacg
gagctgcccctgctgcgggcagctctcaaggagaccttgaggctgtaccccgtgggtatc
tttgtggaacgccgggtgagctcagacttggtgctgcagaactaccacgtcccggccggg
accctggtcaaggtgtgcctctactctctgggccgaaaccccagcgtgctcgccaggccc
gagagctaccatccgcagcgctggctgaactcgagggccgccggcagcaggttgatgcac
ctggccttcggcttcggcgtgcgccagtgcctggggcggcgcctggcggaggtggagatg
ctcctatttctgcaccacgtgctgaaaggcttcctggtggacacgctgacgcaggaggac
gtgcggatgatctaccgctacgtcctcatgccctccagcctccccctgctgaccttccgg
gccaccagctag

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