KEGG   Mycobacterium leprae TN: ML1705
Entry
ML1705            CDS       T00047                                 
Symbol
ligA
Name
(GenBank) DNA ligase
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
mle  Mycobacterium leprae TN
Pathway
mle03030  DNA replication
mle03410  Base excision repair
mle03420  Nucleotide excision repair
mle03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:mle00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    ML1705 (ligA)
   03410 Base excision repair
    ML1705 (ligA)
   03420 Nucleotide excision repair
    ML1705 (ligA)
   03430 Mismatch repair
    ML1705 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mle03032]
    ML1705 (ligA)
   03400 DNA repair and recombination proteins [BR:mle03400]
    ML1705 (ligA)
Enzymes [BR:mle01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     ML1705 (ligA)
DNA replication proteins [BR:mle03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     ML1705 (ligA)
DNA repair and recombination proteins [BR:mle03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     ML1705 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     ML1705 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     ML1705 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      ML1705 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD PTCB-BRCT HHH Bac_small_YrzI
Other DBs
NCBI-ProteinID: CAC30658
Pasteur: ML1705
UniProt: O33102
LinkDB
Position
complement(2055744..2057828)
AA seq 694 aa
MSSPEADPIGPEVLQQWRKLTEEVREHQFRYYVRDAPIISDAEFDALLDRLTVLEEQHPE
LCTPDSPTQLVGGAGFMTDFVATEHLERMFSLDNAFSGDELNAWVTRIRAEIGNDAHYLC
ELKIDGVALSLVYRDGRLTRATTRGDGRTGEDVTLNARTIEDVPERLTVSDIYPLPEVLE
VRGEVFFRVVDFQALNTSLVEEGKNPFANPRNSAAGSLRQKDPAVTAHRKLRMICHGLGH
IEGFRPATQHQAYLALRDWGLPVSEHTTLVNDIAGVQGCIAYWAEHRHEVDHEIDGIVVK
IDEVTLQRRLGSTSRAPRWAIAYKYLPEEAQTKLLDIRVNVGRTGRVTPFAFMTPVKVAG
STVGQATLHNPSEVKRKGVLIGDTVVIRKAGDVIPEVLGPVVDLRDGSEREFVMPTTCPE
CGTTLAPEKEGDADIRCPNARSCPGQLRERVFHVASRSALDIQGLGYEAGVALLAAQVIT
SEGDLFTLTEKALLRTELFRNKAGELSANGKRLLVNVDKAKTAPLWRVLVALSIRHVGPT
AARALATEFGSVDAILAASPEQLAAVEGVGTTIAAAVTEWFTVDWHRVIVNKWRAAGVRM
VDERDTSVLPTCEGLTIVVTGSLAGFSRDDAKEAIVARGGKVAGSVSKKIAYVVVGDLPG
YKYDKAVELGVPILNEDGFRLLLEQGPPVQQVVD
NT seq 2085 nt   +upstreamnt  +downstreamnt
gtgagttcccccgaagctgaccctatcggacccgaggtgttgcagcagtggcgaaagctg
accgaagaggtgcgtgaacaccagttccgttactatgtgcgtgacgcgccgatcatctct
gacgcggagtttgatgctctgctggacaggctcactgtgctggaggaacagcatcccgag
ctgtgcacgcccgattcacctacccagctggtcggcggtgctggcttcatgactgatttc
gtggcgaccgagcatctcgaacggatgttcagcctcgacaacgccttcagtggggatgaa
ctcaatgcctgggtcactcgcatccgcgcagagatcggtaatgacgcccattatttgtgt
gagctcaagatcgacggtgtcgcattgtcgttggtctaccgggatggacgcctgacccgc
gccacgactcggggcgatggtcgcaccggcgaagacgtcacgctgaacgcgcggaccatc
gaagatgtgccggaacggctgaccgtcagcgatatttacccgctgccagaggttcttgag
gtccgcggcgaggtgttcttccgagtggtggactttcaagcgcttaacacgagcctcgtt
gaggagggcaagaatccgttcgctaacccacgaaacagcgcggcgggctcgctgcgccag
aaggatccggcggtcacggctcaccgtaaactgcgaatgatctgtcatggactggggcac
atcgaaggctttcgtcccgctacccagcatcaggcttacttagctttacgggactggggg
ttgccggtgtccgagcatacgacgctggtcaacgacatagctggcgtccagggatgcatc
gcatactgggccgaacatcgtcacgaggtggaccatgaaatcgacgggatagtggtcaaa
atcgacgaggttacgttgcagcgcaggctgggttccacctcgcgagctccacgatgggcc
atcgcttacaagtacctacccgaggaggcgcagaccaagctgctcgacatccgggtgaac
gtcggccgcaccggtcgggttacgccattcgcgttcatgacgcccgtgaaagttgccggg
tcgacggtcgggcaggcgaccttgcacaacccttctgaggtcaaacgcaaaggtgtgctg
atcggtgacaccgtggtgatccgcaaggccggcgacgtgattcccgaagttttgggacct
gtggttgacttgcgcgacgggtccgaacgtgaatttgtgatgcccacaacgtgtcccgag
tgcggtactacgttagcgccagaaaaggaaggcgatgccgacatccgttgccccaatgcc
aggagctgcccggggcaactgcgagagcgagtgtttcacgtcgctagccgcagcgctctg
gacattcaggggttgggttacgaggccggtgtggcgttgctggctgcgcaagtgatcact
agcgagggcgacctgttcaccctcaccgagaaggccttgttgcgcaccgagcttttccgc
aacaaggcaggggagttgtcggcgaatggcaaacggttgctagtcaacgtcgacaaagcc
aaaactgcaccgctgtggcgagtgctggtggcgttgtcgatccggcatgtcgggccgacg
gctgcgcgagccttggccaccgagttcggcagcgttgacgcaatcttggccgcgtcccct
gaacaactggccgctgtcgagggtgtagggaccaccatcgcggccgcggttaccgagtgg
ttcaccgtcgactggcatcgcgtgattgtcaataagtggcgggctgccggggtgcggatg
gtcgatgagcgtgacaccagcgtgctgcccacatgcgaagggttgaccatcgtggtcact
ggttctttagcagggttttcccgtgacgatgccaaggaggcgatcgtggcgcgcggaggc
aaggtcgctggttcggtatcgaagaagatcgcctacgtggtcgtaggcgacttgccggga
tacaaatatgacaaggcggtcgagctcggggtgccgatcctcaacgaggacgggtttcgc
ctgttgcttgagcagggacctccggtgcagcaagtcgttgactag

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