Myotis davidii (David's myotis): 102754742 Help Entry 102754742         CDS       T02992                                  Symbol PTK2 Name (RefSeq) protein tyrosine kinase 2   KO K05725   focal adhesion kinase 1 [EC:2.7.10.2] Organism myd  Myotis davidii (David's myotis) Pathway myd01522   Endocrine resistance myd04012   ErbB signaling pathway myd04062   Chemokine signaling pathway myd04148   Efferocytosis myd04151   PI3K-Akt signaling pathway myd04360   Axon guidance myd04370   VEGF signaling pathway myd04510   Focal adhesion myd04670   Leukocyte transendothelial migration myd04810   Regulation of actin cytoskeleton myd04935   Growth hormone synthesis, secretion and action myd05100   Bacterial invasion of epithelial cells myd05135   Yersinia infection myd05146   Amoebiasis myd05163   Human cytomegalovirus infection myd05165   Human papillomavirus infection myd05170   Human immunodeficiency virus 1 infection myd05200   Pathways in cancer myd05202   Transcriptional misregulation in cancer myd05205   Proteoglycans in cancer myd05208   Chemical carcinogenesis - reactive oxygen species myd05222   Small cell lung cancer myd05417   Lipid and atherosclerosis myd05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:myd00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     102754742 (PTK2)    04370 VEGF signaling pathway     102754742 (PTK2)    04151 PI3K-Akt signaling pathway     102754742 (PTK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     102754742 (PTK2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     102754742 (PTK2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     102754742 (PTK2)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     102754742 (PTK2)    04062 Chemokine signaling pathway     102754742 (PTK2)   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     102754742 (PTK2)   09158 Development and regeneration    04360 Axon guidance     102754742 (PTK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102754742 (PTK2)    05202 Transcriptional misregulation in cancer     102754742 (PTK2)    05205 Proteoglycans in cancer     102754742 (PTK2)    05208 Chemical carcinogenesis - reactive oxygen species     102754742 (PTK2)   09162 Cancer: specific types    05222 Small cell lung cancer     102754742 (PTK2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102754742 (PTK2)    05163 Human cytomegalovirus infection     102754742 (PTK2)    05165 Human papillomavirus infection     102754742 (PTK2)   09171 Infectious disease: bacterial    05135 Yersinia infection     102754742 (PTK2)    05100 Bacterial invasion of epithelial cells     102754742 (PTK2)   09174 Infectious disease: parasitic    05146 Amoebiasis     102754742 (PTK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102754742 (PTK2)    05418 Fluid shear stress and atherosclerosis     102754742 (PTK2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102754742 (PTK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:myd01001]     102754742 (PTK2)    01009 Protein phosphatases and associated proteins [BR:myd01009]     102754742 (PTK2) Enzymes [BR:myd01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102754742 (PTK2) Protein kinases [BR:myd01001]  Non-receptor tyrosine kinases   FAK family    102754742 (PTK2) Protein phosphatases and associated proteins [BR:myd01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      102754742 (PTK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Focal_AT Pkinase FERM_C_FAK1 FERM_N_2 FERM_M Kinase-like Haspin_kinase FERM_F2 GIT1_C ABC1 Motif Other DBs NCBI-GeneID:  102754742 NCBI-ProteinID:  XP_006753316 LinkDB All DBs Position Un AA seq 1106 aa AA seqDB search MLLELAGRQALKPAGAGCMEKSGCSPFPVCWAKEYDRYLASSKIMAAAYLDPNLNHTPNS SAKTHLGTGAERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK VKHVACYGFRLSHLRSEEVHWLHLDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ FTEDKPTLNFFYQQVKSDYMLEIADQVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL ANSEKQGVRTHAVSVSETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIG EGQFGDVHQGTYVSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGV ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAA RNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFG VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF TELKAQLSTILEEEKAQHEERVRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGF YPSPQHMVQTNHYQVSGYPGSHGIPALAGSMYPGQASLLDQTDSWNHRPQEMCMWPPSVE DPAALDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSVDREDA SLQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLAGLSSPGDSYNEGVKPWRLQP QEISPPPTANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLA TVAETIPGLPASTHREVEMAQKLLNSDLGELISKMRLAQQHVLTSLQQEYKKQMLTAAHA LAVDAKNLLDVIDQARLKMLGQARPH NT seq 3321 nt NT seq  +upstreamnt  +downstreamnt atgttgctggaactggcgggccgacaggccctgaagccagcaggggccggctgtatggag aagagcggctgtagcccattcccagtgtgttgggctaaagaatatgacaggtacctagca tctagcaaaataatggcagctgcttacctggacccaaacttgaatcacacaccgaattcg agtgccaagacgcacctgggcactggtgcggaaaggtccccgggagccatggagcgagtg ctaaaagtctttcattattttgaaagcaacagcgagccgaccacgtgggccagtattatc aggcatggagatgctacggatgtcaggggcatcattcagaagatcgtggacagtcacaaa gtgaagcacgtggcctgctacggatttcggctcagtcacctccggtcagaggaggtgcac tggctccacctggacatgggcgtctccagcgtgagggagaagtacgagctcgcacacccg ccggaggagtggaagtatgaattgagaattcgttatttgccaaaaggatttctaaaccag tttactgaagacaagccaactttgaatttcttctatcaacaggtgaagagtgattatatg ttggagatcgcggaccaagtagaccaggacatcgctttgaagttgggttgtctagaaata cggcgatcgtactgggagatgcggggcaatgcactggagaagaagtctaactatgaagta ttagaaaaagatgttggtttgaagcggtttttccccaggagtttactggattctgtcaag gccaaaacgctcagaaaactgatccagcagacgttcaggcagttcgccaacctcaaccgc gaggagagcatcctgaagttcttcgagatcctctccccagtgtacaggttcgacaaggag tgcttcaagtgcgcgctcgggtcaagctggattatttcggtggagctggcgatcggcccc gaggaaggcatcagctacctcacagacaagggctgcaatcccacacacctggccgacttc aatcaagtgcagaccatccagtattcaaacagcgaggacaaggacaggaaaggcatgctc cagctcaagatcgcgggcgcgcctgagcctctgacggtgacagcaccgtccctgaccatt gccgagaacatggccgacttgatcgatgggtactgccggctggtgaacggagcctcccag tccttcatcatccgaccccagaaagaaggcgaacgggctttgccgtcaataccaaagctg gccaacagcgagaagcagggcgtgcggacacatgcggtctccgtgtcagaaaccgacgac tatgccgagatcatagacgaagaggacacctacaccatgccctcaaaaagctatggaata gatgaagccagagattatgagattcaaagagaaagaatagagctgggacgatgcattgga gaaggccagttcggagacgtccaccaaggcacttacgtgagccccgagaatccagctttg gcggttgcaattaaaacatgtaaaaactgtacttccgacagcgtgagagagaagttcctt caagaagccttaaccatgcgccagtttgaccaccctcatatcgtgaagttgattggcgtc atcacggagaaccctgtctggatcatcatggagctgtgcactctcggagagctgcggtca tttctgcaagtccggaagtacagtttggatctggcgtccttgatcctgtatgcctaccag cttagcacagctctcgcgtacctggagagcaagagatttgtgcacagggacattgctgct cggaatgttctggtgtcctcaaatgattgcgtgaaattaggagactttggattatcccga tacatggaagacagtacttactacaaagcttccaaaggaaaattgcctattaaatggatg gctccagagtcgatcaattttcgacgctttacctcagctagcgatgtgtggatgtttggt gtatgtatgtgggagatactgatgcatggtgtgaagccctttcaaggagtgaagaacaat gatgtgatcgggcgcattgagaatggggagagattgccaatgcctcccaattgccctccc accctctacagccttatgacgaaatgctgggcctatgaccccagcaggcggccccggttc actgagctcaaggctcagctcagcacaatcttggaggaggagaaggctcagcacgaggag cgcgtgaggatggagtccaggcgacaggtcaccgtgtcctgggactccggagggtccgac gaagctccgcccaagcccagcaggcctggttatcctagtccgaggtccagtgaagggttt tatcccagcccgcagcacatggtgcagaccaaccattaccaggtctctggttaccctggc tcccacggaatcccagccctggcgggcagcatgtacccggggcaggcatccctcttggac cagacagactcgtggaatcacaggccccaggagatgtgcatgtggccgcccagcgtggag gaccccgcggcgctggacctgcgcgggatcggacaggtgctgcccacacacctgatggag gagcggctgatccggcagcagcaggagatggaggaggaccagcgctggctggagaaagag gagaggttcctgaaacccgacgtgcggctctcccgaggcagcgtggacagggaggatgcg agtctccagggcccgactggaaaccagcacatctaccagccggtggggaagccagatcct gcagctccaccaaagaagccaccacgccccggagcccccggccacctgggcagccttgcc ggcctcagcagccccggggacagctacaacgagggcgtcaagccgtggaggctgcagccc caggagatcagccccccacccacggccaacctggaccgctccaatgacagggtgtacgag aacgtgacgggcctggtgaaggcggtcatcgagatgtccagcaagatccagcccgccccg cccgaggagtacgtgcccatggtgaaggaagtcggcctggccctgaggacgctgttggcc actgtggccgagaccatccctggcctgccggccagcacacaccgcgaggttgagatggcc cagaagctgctcaactcggacctgggcgagctcatcagcaagatgcggctggcccagcag catgtcctcaccagcctgcagcaggagtacaagaagcagatgctgacggccgcgcacgcc ctggccgtggacgccaagaacctgctggacgtcattgaccaggccagactgaagatgctg gggcaggcgaggccgcactga

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