KEGG   NETWORK: N00932
Entry
N00932                      Network                                

Name
Escherichia NleH1 to TNF-NFKB signaling pathway
Definition
NleH1 -| RPS3 -> NFKB
  Expanded
K16042 -| 6188 -> (4790+5970)
Class
nt06123 TNF signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05130  Pathogenic Escherichia coli infection
Disease
H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
H00278  Enteropathogenic Escherichia coli (EPEC) infection
Gene
6188  RPS3; ribosomal protein S3
4790  NFKB1; nuclear factor kappa B subunit 1
5970  RELA; RELA proto-oncogene, NF-kB subunit
Perturbant
K16042 (NleH1)  nleH; non-LEE-encoded effector NleH
Reference
  Authors
Gao X, Wan F, Mateo K, Callegari E, Wang D, Deng W, Puente J, Li F, Chaussee MS, Finlay BB, Lenardo MJ, Hardwidge PR
  Title
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function.
  Journal
PLoS Pathog 5:e1000708 (2009)
DOI:10.1371/journal.ppat.1000708
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