Nomascus leucogenys (northern white-cheeked gibbon): 100580437
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Entry
100580437 CDS
T03265
Gene name
CACNA1C
Definition
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010
MAPK signaling pathway
nle04020
Calcium signaling pathway
nle04022
cGMP-PKG signaling pathway
nle04024
cAMP signaling pathway
nle04260
Cardiac muscle contraction
nle04261
Adrenergic signaling in cardiomyocytes
nle04270
Vascular smooth muscle contraction
nle04713
Circadian entrainment
nle04720
Long-term potentiation
nle04723
Retrograde endocannabinoid signaling
nle04724
Glutamatergic synapse
nle04725
Cholinergic synapse
nle04726
Serotonergic synapse
nle04727
GABAergic synapse
nle04728
Dopaminergic synapse
nle04742
Taste transduction
nle04911
Insulin secretion
nle04912
GnRH signaling pathway
nle04921
Oxytocin signaling pathway
nle04924
Renin secretion
nle04925
Aldosterone synthesis and secretion
nle04927
Cortisol synthesis and secretion
nle04929
GnRH secretion
nle04930
Type II diabetes mellitus
nle04934
Cushing syndrome
nle04935
Growth hormone synthesis, secretion and action
nle05010
Alzheimer disease
nle05020
Prion disease
nle05022
Pathways of neurodegeneration - multiple diseases
nle05031
Amphetamine addiction
nle05410
Hypertrophic cardiomyopathy
nle05412
Arrhythmogenic right ventricular cardiomyopathy
nle05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100580437 (CACNA1C)
04020 Calcium signaling pathway
100580437 (CACNA1C)
04024 cAMP signaling pathway
100580437 (CACNA1C)
04022 cGMP-PKG signaling pathway
100580437 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100580437 (CACNA1C)
04929 GnRH secretion
100580437 (CACNA1C)
04912 GnRH signaling pathway
100580437 (CACNA1C)
04921 Oxytocin signaling pathway
100580437 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
100580437 (CACNA1C)
04924 Renin secretion
100580437 (CACNA1C)
04925 Aldosterone synthesis and secretion
100580437 (CACNA1C)
04927 Cortisol synthesis and secretion
100580437 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
100580437 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
100580437 (CACNA1C)
04270 Vascular smooth muscle contraction
100580437 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
100580437 (CACNA1C)
04727 GABAergic synapse
100580437 (CACNA1C)
04725 Cholinergic synapse
100580437 (CACNA1C)
04728 Dopaminergic synapse
100580437 (CACNA1C)
04726 Serotonergic synapse
100580437 (CACNA1C)
04720 Long-term potentiation
100580437 (CACNA1C)
04723 Retrograde endocannabinoid signaling
100580437 (CACNA1C)
09157 Sensory system
04742 Taste transduction
100580437 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
100580437 (CACNA1C)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100580437 (CACNA1C)
05020 Prion disease
100580437 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
100580437 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
100580437 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100580437 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
100580437 (CACNA1C)
05414 Dilated cardiomyopathy
100580437 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100580437 (CACNA1C)
04934 Cushing syndrome
100580437 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
nle04040
]
100580437 (CACNA1C)
Ion channels [BR:
nle04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100580437 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
GPHH
Ca_chan_IQ
PKD_channel
DUF4834
Motif
Other DBs
NCBI-GeneID:
100580437
NCBI-ProteinID:
XP_030660370
Ensembl:
ENSNLEG00000002735
LinkDB
All DBs
Position
23
AA seq
2135 aa
AA seq
DB search
MVNENTRMYIPEENHQGSNYGSARPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
QEGIAAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITME
GWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQK
LREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGD
IEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIAS
EHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILET
ILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFII
IFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPS
FPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTAS
PEKKQELMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPNENEDKSPYPNPETT
GEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFT
NLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGS
FCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVF
VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH
PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS
IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI
PKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFT
VEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRI
SITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFG
KIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEG
ETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAE
YDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLF
ALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFL
IQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAM
KEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESP
SHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIR
VQEVAWKLSSSRCHSQESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQD
DENRQLTLPEEDKRDIQQSPKRGFLHSASLGRRASFHLECLKRQKDRGGDISQKTVLPLH
LVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKL
NSSFPSIHCGSWAETTPGGGGSSAARRARPVSLMVPSQAGAPGRQFHGSASSLVEAVLIS
EGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDA
GQDRAGGEEDAGCARARGRLSEEELQDSRVYVSSL
NT seq
6408 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgagaatacgaggatgtacattccagaggaaaaccaccaaggttccaactat
gggagcgcacgccccgcccatgccaacatgaatgccaatgcggcagcggggctggcccct
gaacacatccccaccccgggggccgccctgtcctggcaggcggccatcgacgcagcccgg
caggctaagctgatgggcagcgctggcaatgcgaccatctccacagtcagctccacgcag
cggaagcggcagcaatatgggaaacccaagaagcagggcagcaccacggccacacgcccg
ccccgagccctgctctgcctgaccctgaagaaccccatccggagggcctgcatcagcatt
gtcgaatggaaaccatttgaaataattattttactgactatttttgccaattgtgtggcc
ttagcgatctatattccctttccagaagatgattccaacgccaccaattccaacctggaa
cgagtggaatatctctttctcataatttttacggtggaagcgtttttaaaagtcatcgcc
tatggactcctctttcaccccaatgcctacctccgcaacggctggaacctactagatttt
ataattgtggttgtggggctttttagtgcaattttagaacaagcaaccaaagcagacggg
gcaaacgctctcggagggaaaggggccggatttgatgtgaaggcgctgagggccttccgc
gtgctgcgccccctgcggctggtgtccggagtcccaagtctccaggtggtcctgaattcc
atcatcaaggccatggtccccctgctgcacatcgccctgcttgtgctgtttgtcatcatc
atctacgccatcatcggcctggagctcttcatggggaagatgcacaagacctgctacaac
caggagggcatagcagcagaagatgacccttccccttgtgcactggaaacaggccacggg
cggcagtgccagaacggcacggtgtgcaagcccggctgggatgggcccaagcacggcatc
accaactttgacaactttgccttcgccatgctcacggtgttccagtgcatcaccatggag
ggctggacggacgtgctgtactggatgcaggacgctatgggctatgagttaccctgggtg
tattttgtcagtctggtcatctttggatcctttttcgttctaaatctggttctcggtgtg
ttgagcggagagttttccaaagagagggagaaggccaaggcccggggagatttccagaag
ctgcgggagaagcagcagctagaagaggatctcaaaggctacctggactggatcactcag
gccgaagacatcgatcctgagaacgaggacgagggcatggatgaggagaagccccgaaac
atgagcatgcccaccagtgagaccgagtccgtcaacaccgaaaacgtggctggaggtgac
atcgagggagaaaactgcggggccaggctggcccaccggatctccaagtcaaagttcagc
cgctactggcgccggtggaatcggttctgcagaagaaagtgccgcgccgcagtcaagtct
aatgtcttctactggctggtgattttcctggtgttcctcaacacgctcaccattgcctct
gagcactacaaccagccccactggctcaccgaagtccaagacacggcgaacaaggccctg
ctggccctgttcacagcggagatgctcctgaagatgtacagcctgggcctgcaggcctat
ttcgtgtccctcttcaaccgctttgactgcttcgtcgtgtgtggcggcatcctggagacc
atcctggtggagaccaagatcatgtccccactgggcatctccgtgctcagatgtgtccgg
ctgctgaggatattcaagatcacgaggtactggaactccttgagcaacctggtggcatcc
ttgctgaactctgtgcgctccatcgcctccctgctccttctcctcttcctcttcatcatc
atcttctccctcctggggatgcagctctttggaggaaagttcaactttgatgagatgcag
acccggaggagcacatttgataacttcccccagtccctcctcactgtgtttcagatcctg
accggggaggactggaattcggtgatgtatgatgggatcatggcttatggcggcccctct
tttccagggatgttagtctgtatttacttcatcatcctcttcatctgtggaaactatatc
ctactgaatgtgttcttggccattgctgtggacaacctggctgatgctgagagcctcaca
tctgcccaaaaggaggaggaagaggagaaggagagaaagaagctggccaggactgccagc
ccagagaagaaacaagagttgatggagaagccggcagtggaggaatccaaggaggagaag
attgagctgaaatccatcacggctgacggagagtctccacccaccaccaagatcaacatg
gatgacctccagcccaatgaaaatgaggataagagcccctaccccaacccagaaactaca
ggagaagaggatgaggaggagccagagatgcctgtcggccctcgcccacgaccactctct
gagcttcaccttaaggaaaaagcagtgcccatgccagaagccagcgcatttttcatcttc
agctctaacaacaggtttcgcctccagtgccaccgcattgtcaatgacacgatcttcacc
aacctgatcctcttcttcattctgctcagcagcatttccctggctgctgaggacccggtc
cagcacacctccttcaggaaccatatcctaggcaatgcagactatgtcttcactagtatc
tttacattagaaattatccttaagatgactgcttatggggctttcctgcacaagggctct
ttctgccgtaactacttcaacatcctggacctgctggtggtcagcgtgtccctcatctcc
tttggcatccagtccagtgcaatcaatgtcgtgaagatcttgcgagtcctgcgagtactc
aggcccctgagggccatcaacagggccaaggggctaaagcatgtggttcagtgtgtgttt
gtcgccatccggaccatcgggaacatcgtgattgtcaccaccctgctgcagttcatgttt
gcctgcattggggtccagctcttcaagggaaagctgtacacctgttcagacagttccaag
cagacagaggcggaatgcaagggcaactacatcacgtacaaagacggggaggttgaccac
cccatcatccaaccccgcagctgggagaacagcaagtttgactttgacaatgttctggca
gccatgatggctctcttcactgtctccaccttcgaagggtggccagagctgctgtaccgc
tccatcgactcccacacggaagacaagggccccatctacaactaccgcgtggagatctcc
atcttcttcatcatctacatcatcatcatcgccttcttcatgatgaacatcttcgtgggc
ttcgtcatcgtcaccttccaggagcagggggagcaggagtacaagaactgtgagctggac
aagaaccagcgacagtgcgtggaatacgccctcaaggcccggcccctgcggaggtacatc
cccaagaaccagcaccagtacaaagtgtggtacgtggtcaactccacctacttcgagtac
ctgatgttcgtcctcatcctgctcaacaccatctgcctggccatgcagcactacggccag
agctgcctgttcaaaattgccatgaacatcctcaacatgctcttcactggcctcttcacc
gtggagatgatcctgaagctcattgccttcaaacccaagcactatttctgtgatgcatgg
aatacatttgatgccttgattgttgtgggtagcattgttgatatagcaatcaccgaggta
aacccagctgaacatacccaatgctctccctctatgaacgcagaggaaaactcccgcatc
tccatcaccttcttccgcctgttccgggtcatgcgcctggtgaagctgctgagccgtggg
gagggcatccggacgctgctgtggaccttcatcaagtccttccaggccctgccctatgtg
gccctcctgatcgtgatgctattcttcatctacgcggtgatcgggatgcaggtgtttggg
aaaattgccctgaatgataccacagagatcaaccggaacaacaactttcagaccttcccc
caggccgtgctgctcctcttcaggtgtgccactggggaggcctggcaggacatcatgctg
gcctgcatgccaggcaagaagtgtgccccggagtctgagcccagcaacagcacggagggt
gaaacgccctgtggcagcagctttgctgtcttctacttcatcagcttctatatgctctgt
gccttcctgatcatcaacctctttgtagctgtcatcatggacaactttgactacctgaca
agggactggtccatccttggtccccaccacctggatgagtttaaaagaatctgggcagag
tatgaccctgaagccaagggtcgtatcaaacacctggatgtggtgaccctcctccggcgg
attcagcccccactaggttttgggaagctgtgccctcaccgcgtggcttgcaaacgcctg
gtctccatgaacatgcctctgaacagcgacgggacagtcatgttcaatgccaccctgttt
gccctggtcaggacggccctgaggatcaaaacagaagggaacctagaacaagccaatgag
gagctgcgggcgatcatcaagaagatctggaagcggaccagcatgaagctgctggaccag
gtggtgccccctgcaggtgatgatgaggtcaccgttggcaagttctatgccaccttcctg
atccaggagtacttccggaagttcaagaagcgcaaagagcagggccttgtgggcaagccc
tcccagaggaacgcactgtctctgcaggctggcttgcgcacgctgcatgacatcgggcct
gagatccgacgggccatctctggagatctcaccgctgaggaagagctggacaaggccatg
aaggaggctgtgtccgctgcttctgaagatgacatcttcaggcgggccggtggcctgttc
ggcaaccacgtcagctactaccaaagcgacggccggagcgccttcccccagaccttcacc
actcagcgcccgctgcacatcaacaaggcgggcagcagccagggtgacactgagtcgccg
tcccacgagaagctggtggactccaccttcacccccagcagctactcgtccaccggctcc
aacgccaacatcaacaacgctaacaacactgccctgggtcgcctccctcgccctgccggc
taccccagcacagtcagcactgtggagggccatgggccccccttgtcccctgccatccgg
gtgcaggaggtggcgtggaagctcagctccagcaggtgccattcccaggagagccaggca
gccatggcgggtcaggaggagacgtctcaggatgagacctatgaagtgaagatgaaccat
gacacggaggcctgcagtgagcccagcctgctctccacagagatgctctcctaccaggat
gacgaaaatcggcaactgacgctcccagaggaggacaagagggacatccagcaatctccg
aagaggggtttcctccactctgcctcactaggtcgaagggcctccttccacctggaatgt
ctgaagcgacagaaggaccgagggggagacatctctcagaagacagtcctgcccttgcat
ctggttcatcatcaggcattggcagtggcaggcctgagccccctcctccagagaagccat
tcccctgcctcattccccaggccttttgccaccccaccagccacacctggcagccgaggc
tggcccccacagcccgtccccaccctgcggctggagggggtcgagtccagtgagaaactc
aacagcagcttcccatccatccactgcggctcctgggctgagaccacccccggtggcggg
ggcagcagcgccgcccggagagcccggcccgtctccctcatggtgcccagccaggctggg
gccccagggaggcagttccacggcagtgccagcagcctggtggaagcggtcttgatttca
gaaggactggggcagtttgctcaagatcccaagttcatcgaggtcaccacccaggagctg
gccgacgcctgcgacatgaccatagaggagatggagagcgcggccgacaacatcctcagc
gggggcgccccacagagccccaatggcgccctcttaccctttgtgaactgcagggacgcg
gggcaggaccgagccgggggcgaagaggacgcgggctgtgcgcgcgcgcgggggcggctg
agcgaggaggagctccaggacagcagggtgtacgtcagcagcctgtag
DBGET
integrated database retrieval system
