Neomonachus schauinslandi (Hawaiian monk seal): 110588209
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Entry
110588209 CDS
T08474
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04014
Ras signaling pathway
nsu04072
Phospholipase D signaling pathway
nsu04148
Efferocytosis
nsu04360
Axon guidance
nsu04625
C-type lectin receptor signaling pathway
nsu04630
JAK-STAT signaling pathway
nsu04650
Natural killer cell mediated cytotoxicity
nsu04660
T cell receptor signaling pathway
nsu04670
Leukocyte transendothelial migration
nsu04722
Neurotrophin signaling pathway
nsu04920
Adipocytokine signaling pathway
nsu04931
Insulin resistance
nsu05168
Herpes simplex virus 1 infection
nsu05205
Proteoglycans in cancer
nsu05208
Chemical carcinogenesis - reactive oxygen species
nsu05211
Renal cell carcinoma
nsu05220
Chronic myeloid leukemia
nsu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
110588209 (PTPN11)
04630 JAK-STAT signaling pathway
110588209 (PTPN11)
04072 Phospholipase D signaling pathway
110588209 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
110588209 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
110588209 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
110588209 (PTPN11)
04660 T cell receptor signaling pathway
110588209 (PTPN11)
04670 Leukocyte transendothelial migration
110588209 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
110588209 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
110588209 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
110588209 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
110588209 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
110588209 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110588209 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
110588209 (PTPN11)
05211 Renal cell carcinoma
110588209 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
110588209 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
110588209 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
nsu01009
]
110588209 (PTPN11)
Enzymes [BR:
nsu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
110588209 (PTPN11)
Protein phosphatases and associated proteins [BR:
nsu01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
110588209 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
DSPc
PTPlike_phytase
Y_phosphatase3
Motif
Other DBs
NCBI-GeneID:
110588209
NCBI-ProteinID:
XP_021554169
EnsemblRapid:
ENSNSCG00000008340
UniProt:
A0A2Y9HW85
LinkDB
All DBs
Position
14:complement(82633404..82715286)
Genome browser
AA seq
613 aa
AA seq
DB search
MKEILLGAREESSEVDGIHGGLRYLWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGD
FTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKY
PLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGES
NDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR
INAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYK
NILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVND
FWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRE
LKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCS
AGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQH
YIETLQRRIEEEQKSKRKGHEYTNIKYSLTDQTSGDQSPLPPGTPTPSCAEMREDNARVY
ENVGLMQPQKSFR
NT seq
1842 nt
NT seq
+upstream
nt +downstream
nt
atgaaggaaatcttgttgggagctagagaggaatcctctgaagtggatggcattcatggt
ggacttcgttatttatggtttcacccaaacatcactggcgtggaggcagaaaacctgctg
ttgacaagaggagttgatggcagttttttggcgaggcccagtaaaagcaaccctggagac
ttcaccctttccgtcagaagaaatggcgctgtcacccacatcaagattcagaacactggt
gattactatgacttgtacggaggggagaagtttgccactttggctgagttggtccagtat
tacatggaacatcatgggcaattaaaagagaagaatggagatgttattgagcttaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattactaactgagaaaggaaaacacggtagctttctggtacgagagagc
cagagccaccccggagattttgttctgtctgtccgaactggtgacgacaaaggggagagc
aatgatggcaagtctaaagtgacccacgtcatgatccgctgtcaggaactgaaatatgat
gttggtggaggagaacggtttgactctttaacagatcttgtggagcattacaagaagaat
cccatggtggaaacattgggcacagtactacaactcaagcagcccctcaacacaacacgt
atcaatgctgctgaaatagaaagccgggttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgaaaagagggtcagaggcaagaaaataagaacaaaaatagatataaa
aacatcctgccctttgatcataccagggttgtcctacacgatggtgatcccaatgagcct
gtttcagattacatcaatgcaaatattatcatgcctgagtttgaaaccaaatgcaacaat
tcaaagcccaaaaaaagttacatcgccacacaaggctgcctgcagaacacggtgaacgac
ttttggcggatggtatttcaggagaactcccgagtgatcgtcatgacaacgaaggaggtg
gagagaggaaagagtaaatgtgtcaaatactggcctgacgagtatgctctaaaagaatac
ggggtcatgcgtgttaggaacgtcaaagaaagtgctgctcatgactatacattaagagaa
cttaaactttcaaaagttggacaagggaatacagagagaaccgtgtggcaataccacttt
cggacctggccggaccacggagtgcccagtgaccctgggggcgtgctggacttcctggag
gaggtccaccataagcaagagagcattatggacgcagggcctgtggtagttcactgcagt
gctggaatcggcaggacagggacgttcattgtgattgatatccttattgacatcatcaga
gagaaaggcgtcgactgtgacatcgatgttcccaaaaccattcagatggtgcggtctcag
aggtcagggatggtccagacagaagcacagtaccggttcatctatatggccgtccagcat
tacattgaaacactacagcgcaggattgaagaagagcagaaaagcaagaggaaagggcat
gaatacacaaatattaagtattctctaacggaccagacaagtggagatcagagtcccctc
ccgcctggtaccccaacaccatcttgtgcagaaatgagagaagataatgctagagtctat
gaaaacgtgggtctgatgcagccgcagaaaagtttcagatga
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