Neomonachus schauinslandi (Hawaiian monk seal): 110589652
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Entry
110589652 CDS
T08474
Symbol
HK1
Name
(RefSeq) hexokinase-1 isoform X1
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00010
Glycolysis / Gluconeogenesis
nsu00051
Fructose and mannose metabolism
nsu00052
Galactose metabolism
nsu00500
Starch and sucrose metabolism
nsu00520
Amino sugar and nucleotide sugar metabolism
nsu00524
Neomycin, kanamycin and gentamicin biosynthesis
nsu01100
Metabolic pathways
nsu01200
Carbon metabolism
nsu01250
Biosynthesis of nucleotide sugars
nsu04066
HIF-1 signaling pathway
nsu04910
Insulin signaling pathway
nsu04930
Type II diabetes mellitus
nsu04973
Carbohydrate digestion and absorption
nsu05230
Central carbon metabolism in cancer
Module
nsu_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
nsu_M00549
Nucleotide sugar biosynthesis, glucose => UDP-glucose
nsu_M00892
UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110589652 (HK1)
00051 Fructose and mannose metabolism
110589652 (HK1)
00052 Galactose metabolism
110589652 (HK1)
00500 Starch and sucrose metabolism
110589652 (HK1)
00520 Amino sugar and nucleotide sugar metabolism
110589652 (HK1)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
110589652 (HK1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110589652 (HK1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
110589652 (HK1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
110589652 (HK1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110589652 (HK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110589652 (HK1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
nsu04131
]
110589652 (HK1)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
110589652 (HK1)
Membrane trafficking [BR:
nsu04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
110589652 (HK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Sec23_helical
UvrD-helicase
Motif
Other DBs
NCBI-GeneID:
110589652
NCBI-ProteinID:
XP_021555866
EnsemblRapid:
ENSNSCG00000001642
UniProt:
A0A2Y9HWE4
LinkDB
All DBs
Position
6:98340284..98403575
Genome browser
AA seq
917 aa
AA seq
DB search
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFKKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQNVHMESEIYDTPENIVH
GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEGILITWTKKFKASGV
EGMDVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKESLLFEGRITPELLTRGKFKTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCISVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQFSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFRLT
KDMLLEVKKRMRAEMDMGLRKQTHEKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPKMPLGF
TFSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLREAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMLEGNDGRMCINMEWGAFGDNGCLDD
IRTIYDRLVDEYSLNAGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG
IFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA
VVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSGIMYQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLREETSS
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
atgatcgccgcgcagctcctggcctattacttcaccgagctgaaggatgaccaagtcaaa
aagattgacaagtatctctatgccatgcggctctccgatgaaactctaatagatatcatg
actcgtttcaagaaggagatgaagaatggcctctcccgggattttaatccaacagccaca
gtcaagatgttgccaacgtttgtaaggtccatccctgatggttcagaaaagggagatttc
attgccctggatcttggcgggtcttcctttcgaattctgagggtacaagtgaatcatgag
caaaaccagaatgttcacatggagtccgagatttacgacaccccggagaacatcgtgcac
ggcagtggaagccagctttttgatcacgtggctgagtgcctgggagacttcatggagaaa
aaaaaaatcaaggacaagaaattacctgtgggattcacgttttctttcccttgtcggcag
tccaaaatagacgagggcatcctgatcacctggacaaagaaatttaaagcgagtggagtg
gagggaatggatgtggtgaagctgcttaacaaagccatcaaaaagcgtggggactacgat
gccaacattgtggccgtggtgaatgacacggtggggaccatgatgacctgtggctatgat
gaccagcagtgtgaagtcggcctcatcatcggcactggcaccaatgcctgctacatggag
gaactgaggcacattgacctggtggaaggcgatgaggggaggatgtgcatcaacacagaa
tggggggccttcggggacgacgggtcgctggaagacatccgcactgagttcgaccgggag
atagaccgtggctctctcaaccccgggaagcagctgtttgagaagatggtcagtggcatg
tacttgggagagctggtgcgactgatcctggtcaagatggccaaggagagcctcttattt
gaagggcggatcaccccggagctgctcacccgggggaagttcaagaccagcgatgtgtca
gccattgagaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga
gtggagccatccgatgacgactgtatttcagtccagcacgtgtgtaccattgtctcattt
cgctctgccaacctggtggctgcaacgctgggcgccatcttgaaccgccttcgagataac
aagggcacacccaggctgcggaccacggttggtgtcgacgggtctctttacaagacgcac
ccacagttttcccggcgtttccacaagactctgaggcgcttggtgcccgactccgatgtg
cgtttcctcctctcggagagcggcagtggcaagggggctgccatggtcaccgcggtggcc
taccgcctggccgagcagcaccgacagatcgaggagaccctggcccacttccgcctcacc
aaggacatgctgctggaggtgaagaagagaatgcgggctgagatggatatgggcctgagg
aagcagacgcacgagaaggccgtggtcaagatgctgccctcctttgtccggagcactcca
gatgggaccgagcatggtgacttcttggcgcttgatcttggaggaacaaatttccgtgtc
ctgctggtgaaaatccgcagtgggaaaaagagaacggtggaaatgcacaacaagatctat
gccattcccattgaaatcatgcagggcaccggggaagagctatttgaccacatagtctcc
tgcatctctgacttcctggactacatggggatcaaaggccccaaaatgcctctgggcttc
acgttctcattcccctgcaagcagacgagcctggatgcgggaatcttgatcacctggaca
aagggttttaaggcaaccgactgcgtggggcacgatgtagcaacattactaagggaagca
ataaaaaggagagaggaatttgacctggacgtggtggctgtggtaaatgacacggtgggc
accatgatgacctgtgcttacgaggagcctacctgcgaggttggactcatcgtagggacc
ggcagcaatgcctgctacatggaagaaatgaagaatgtcgagatgctggaggggaatgac
gggcgcatgtgcatcaacatggagtggggtgcctttggggacaacgggtgtctagatgat
atcagaacaatctatgacagactggtggatgaatattctctaaacgctgggaagcaaagg
tttgagaagatgattagcggtatgtacctgggtgagatcgtccgcaacatcttgatcgac
ttcaccaagaaggggttcctcttccgagggcagatctctgagacactgaagacccggggc
atctttcagaccaaatatctttcccagattgagagtgaccggttagcgctgctccaggtg
cgggccatcctgcagcagctgggcctgaacagcacctgtgacgatagcatcctggtcaag
accgtgtgcggggtggtgtccaagagggctgcacagctgtgcggtgcgggcatggccgcc
gtggtggacaagatccgcgagaacagagggctggaccacctcaacgtgactgtgggcgtg
gatggaacactctacaagcttcatccgcacttctccggaatcatgtaccaaaccgtgaag
gaactgtccccaaaatgtaacgtgtcattcctcctgtccgaagacggtagcggcaagggg
gctgccctcatcacggcagtgggcgtccggctccgggaagagacgagcagctaa
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