| Entry |
|
| Symbol |
HK
|
| Name |
|
| Pathway |
| map00051 | Fructose and mannose metabolism |
| map00520 | Amino sugar and nucleotide sugar metabolism |
| map00524 | Neomycin, kanamycin and gentamicin biosynthesis |
| map01110 | Biosynthesis of secondary metabolites |
| map01120 | Microbial metabolism in diverse environments |
| map01250 | Biosynthesis of nucleotide sugars |
| map04973 | Carbohydrate digestion and absorption |
| map05230 | Central carbon metabolism in cancer |
|
| Module |
| M00001 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate |
| M00549 | UDP-Glc biosynthesis, Glc => UDP-Glc |
| M01015 | GDP-Man biosynthesis, Man => GDP-Man |
|
| Reaction |
| R00299 | ATP:D-glucose 6-phosphotransferase |
| R00760 | ATP:D-fructose 6-phosphotransferase |
| R00867 | ATP:D-fructose 6-phosphotransferase |
| R01326 | ATP:D-mannose 6-phosphotransferase |
| R01600 | ATP:beta-D-glucose 6-phosphotransferase |
| R01786 | ATP:alpha-D-glucose 6-phosphotransferase |
| R01961 | ATP:D-glucosamine 6-phosphotransferase |
| R03920 | ATP:D-fructose 6-phosphotransferase |
|
| Disease |
| H00264 | Charcot-Marie-Tooth disease |
| H00664 | Anemia due to disorders of glycolytic enzymes |
| H02470 | Neurodevelopmental disorder with structural brain abnormalities |
| H02999 | Congenital nonspherocytic hemolytic anemia |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
K00844 HK; hexokinase
00051 Fructose and mannose metabolism
K00844 HK; hexokinase
00052 Galactose metabolism
K00844 HK; hexokinase
00500 Starch and sucrose metabolism
K00844 HK; hexokinase
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
K00844 HK; hexokinase
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
K00844 HK; hexokinase
00524 Neomycin, kanamycin and gentamicin biosynthesis
K00844 HK; hexokinase
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
K00844 HK; hexokinase
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
K00844 HK; hexokinase
09154 Digestive system
04973 Carbohydrate digestion and absorption
K00844 HK; hexokinase
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
K00844 HK; hexokinase
09171 Infectious disease: bacterial
05131 Shigellosis
K00844 HK; hexokinase
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
K00844 HK; hexokinase
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking
K00844 HK; hexokinase
Enzymes [BR:ko01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
K00844 HK; hexokinase
Membrane trafficking [BR:ko04131]
Autophagy
Mitophagy
Other mitophagy associated proteins
K00844 HK; hexokinase
|
| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Kawai S, Mukai T, Mori S, Mikami B, Murata K |
| Title |
Hypothesis: structures, evolution, and ancestor of glucose kinases in the hexokinase family. |
| Journal |
|
| Reference |
|
| Authors |
Nishi S, Seino S, Bell GI |
| Title |
Human hexokinase: sequences of amino- and carboxyl-terminal halves are homologous. |
| Journal |
|
| Sequence |
|
| LinkDB |
|