Oryctolagus cuniculus (rabbit): 100347954
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Entry
100347954 CDS
T03373
Gene name
PDPK1
Definition
(RefSeq) 3-phosphoinositide dependent protein kinase 1
KO
K06276
3-phosphoinositide dependent protein kinase-1 [EC:
2.7.11.1
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu01524
Platinum drug resistance
ocu03320
PPAR signaling pathway
ocu04068
FoxO signaling pathway
ocu04071
Sphingolipid signaling pathway
ocu04140
Autophagy - animal
ocu04150
mTOR signaling pathway
ocu04151
PI3K-Akt signaling pathway
ocu04152
AMPK signaling pathway
ocu04210
Apoptosis
ocu04510
Focal adhesion
ocu04660
T cell receptor signaling pathway
ocu04664
Fc epsilon RI signaling pathway
ocu04722
Neurotrophin signaling pathway
ocu04910
Insulin signaling pathway
ocu04919
Thyroid hormone signaling pathway
ocu04931
Insulin resistance
ocu04960
Aldosterone-regulated sodium reabsorption
ocu05145
Toxoplasmosis
ocu05205
Proteoglycans in cancer
ocu05213
Endometrial cancer
ocu05215
Prostate cancer
ocu05223
Non-small cell lung cancer
ocu05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100347954 (PDPK1)
04071 Sphingolipid signaling pathway
100347954 (PDPK1)
04151 PI3K-Akt signaling pathway
100347954 (PDPK1)
04152 AMPK signaling pathway
100347954 (PDPK1)
04150 mTOR signaling pathway
100347954 (PDPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100347954 (PDPK1)
09143 Cell growth and death
04210 Apoptosis
100347954 (PDPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100347954 (PDPK1)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
100347954 (PDPK1)
04664 Fc epsilon RI signaling pathway
100347954 (PDPK1)
09152 Endocrine system
04910 Insulin signaling pathway
100347954 (PDPK1)
03320 PPAR signaling pathway
100347954 (PDPK1)
04919 Thyroid hormone signaling pathway
100347954 (PDPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100347954 (PDPK1)
09156 Nervous system
04722 Neurotrophin signaling pathway
100347954 (PDPK1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100347954 (PDPK1)
05231 Choline metabolism in cancer
100347954 (PDPK1)
09162 Cancer: specific types
05215 Prostate cancer
100347954 (PDPK1)
05213 Endometrial cancer
100347954 (PDPK1)
05223 Non-small cell lung cancer
100347954 (PDPK1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100347954 (PDPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100347954 (PDPK1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100347954 (PDPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocu01001
]
100347954 (PDPK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ocu04131
]
100347954 (PDPK1)
Enzymes [BR:
ocu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100347954 (PDPK1)
Protein kinases [BR:
ocu01001
]
Serine/threonine kinases: AGC group
PDK1 family
100347954 (PDPK1)
Membrane trafficking [BR:
ocu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Acrosomal exocytosis proteins
100347954 (PDPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
100347954
NCBI-ProteinID:
XP_008250214
Ensembl:
ENSOCUG00000002145
LinkDB
All DBs
Position
Un
AA seq
450 aa
AA seq
DB search
MARTTSHLYDAVPIQSSVVLCSCPSPSMVRTQTESSAAPGIPSGGSRQSPTMEGTTAEAR
PSANALQHAAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHI
IKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD
ETCTRFYTAEIVCALEYLHGKGVIHRDLKPENILLNEDMHIQITDFGTAKVLSPASKQAR
ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLE
YDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESITWENLHQQTPPKL
TAYLPAMSEDDEDCYGNYDNLLSQFGCLQVSASSSSHSLSAADAGPPQRSGSNIEQYIHD
LDTNSFELDLQFSEDEKKLLLEKQAGGNPW
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atggccaggaccaccagccacttgtatgacgccgtccccatccagtccagcgtggtgtta
tgttcctgcccatccccatccatggtgagaacccagactgagtccagcgcagcccctggc
atccccagcggtggcagcaggcagagccccaccatggagggcaccacagccgaggcccgg
cccagtgccaacgccctgcagcatgctgcccagccaccgccacagcctcggaagaaacgg
cctgaagacttcaaatttgggaagattctgggcgaaggctccttctcaaccgttgtcctg
gctcgagaactggcaacctccagagaatatgctattaaaatcctggagaagcggcatatt
ataaaagagaacaaggttccgtatgtgaccagagagcgggatgtgatgtcgcgcctggat
caccccttctttgttaagctttacttcacttttcaggacgacgaaaagctctattttggt
cttagttatgccaaaaatggagaactacttaaatacattcgcaaaatcggttcctttgat
gagacctgtacgcgattttacactgccgagattgtgtgtgctttagagtacttgcatggc
aagggcgtcatccacagggacctgaaaccggagaacatcctgttgaatgaagacatgcac
atccagatcacagacttcggaacagcaaaggtgttgtctccggcgagcaagcaagccagg
gccaactcgttcgtgggaacggcgcagtatgtctctccagagctgctcacggagaagtcg
gcctgcaaaagttcagacctttgggctctgggatgcataatataccagctcgtggcagga
ctaccaccgttccgagccggaaatgaatatcttatatttcagaagatcattaaattggaa
tatgactttccagaaaaattcttccctaaggcaagagaccttgtggaaaaacttttggtt
ttagatgccacaaagcggttaggctgtgaagagatggaagggtatggccctctcaaagct
catccattcttcgagtccatcacgtgggagaatctgcaccagcagacgcctccgaagctc
acggcctacctaccggccatgtctgaggatgacgaggactgctatggcaattatgacaac
ctcctgagccagtttggctgcttgcaggtgtcggcgtcgtcctcctcgcactccctgtcc
gcagcagatgccggcccgccccagaggtcaggcagcaacatagagcagtacatccacgac
ttggacactaattcttttgaactggacctgcagttttctgaagatgagaagaagttgtta
ctggagaagcaggctggtggaaacccctggtaa
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