Entry |
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Symbol |
PDPK1
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Name |
3-phosphoinositide dependent protein kinase-1 [EC: 2.7.11.1]
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Pathway |
map04660 | T cell receptor signaling pathway |
map04664 | Fc epsilon RI signaling pathway |
map04919 | Thyroid hormone signaling pathway |
map04960 | Aldosterone-regulated sodium reabsorption |
map05208 | Chemical carcinogenesis - reactive oxygen species |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
09132 Signal transduction
04011 MAPK signaling pathway - yeast
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
04068 FoxO signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
04071 Sphingolipid signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
04151 PI3K-Akt signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
04152 AMPK signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
04150 mTOR signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09143 Cell growth and death
04210 Apoptosis
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09144 Cellular community - eukaryotes
04510 Focal adhesion
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
04664 Fc epsilon RI signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09152 Endocrine system
04910 Insulin signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
03320 PPAR signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
04919 Thyroid hormone signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09156 Nervous system
04722 Neurotrophin signaling pathway
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09158 Development and regeneration
04360 Axon guidance
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
05208 Chemical carcinogenesis - reactive oxygen species
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
05231 Choline metabolism in cancer
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09162 Cancer: specific types
05215 Prostate cancer
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
05213 Endometrial cancer
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
05223 Non-small cell lung cancer
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09174 Infectious disease: parasitic
05145 Toxoplasmosis
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09167 Endocrine and metabolic disease
04931 Insulin resistance
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
09182 Protein families: genetic information processing
04131 Membrane trafficking
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
Enzymes [BR:ko01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
Protein kinases [BR:ko01001]
Serine/threonine kinases: AGC group
PDK1 family
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
Membrane trafficking [BR:ko04131]
Exocytosis
Calcium ion-dependent exocytosis
Acrosomal exocytosis proteins
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, Reese CB, Cohen P |
Title |
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. |
Journal |
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Sequence |
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Reference |
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Authors |
Pullen N, Dennis PB, Andjelkovic M, Dufner A, Kozma SC, Hemmings BA, Thomas G. |
Title |
Phosphorylation and activation of p70s6k by PDK1. |
Journal |
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Sequence |
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Reference |
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Authors |
Casamayor A, Torrance PD, Kobayashi T, Thorner J, Alessi DR |
Title |
Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast. |
Journal |
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Sequence |
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Reference |
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Authors |
Inagaki M, Schmelzle T, Yamaguchi K, Irie K, Hall MN, Matsumoto K |
Title |
PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast. |
Journal |
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Sequence |
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LinkDB |
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