KEGG   ORTHOLOGY: K06276
Entry
K06276                      KO                                     
Symbol
PDPK1
Name
3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
Pathway
map01524  Platinum drug resistance
map03320  PPAR signaling pathway
map04011  MAPK signaling pathway - yeast
map04068  FoxO signaling pathway
map04071  Sphingolipid signaling pathway
map04140  Autophagy - animal
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04152  AMPK signaling pathway
map04210  Apoptosis
map04360  Axon guidance
map04510  Focal adhesion
map04660  T cell receptor signaling pathway
map04664  Fc epsilon RI signaling pathway
map04722  Neurotrophin signaling pathway
map04910  Insulin signaling pathway
map04919  Thyroid hormone signaling pathway
map04931  Insulin resistance
map04960  Aldosterone-regulated sodium reabsorption
map05145  Toxoplasmosis
map05205  Proteoglycans in cancer
map05208  Chemical carcinogenesis - reactive oxygen species
map05213  Endometrial cancer
map05215  Prostate cancer
map05223  Non-small cell lung cancer
map05231  Choline metabolism in cancer
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04011 MAPK signaling pathway - yeast
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   04068 FoxO signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   04071 Sphingolipid signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   04151 PI3K-Akt signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   04152 AMPK signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   04150 mTOR signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09143 Cell growth and death
   04210 Apoptosis
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   04664 Fc epsilon RI signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09152 Endocrine system
   04910 Insulin signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   03320 PPAR signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   04919 Thyroid hormone signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09158 Development and regeneration
   04360 Axon guidance
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   05208 Chemical carcinogenesis - reactive oxygen species
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   05231 Choline metabolism in cancer
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09162 Cancer: specific types
   05215 Prostate cancer
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   05213 Endometrial cancer
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
   05223 Non-small cell lung cancer
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  PDK1 family
   K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
Membrane trafficking [BR:ko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Acrosomal exocytosis proteins
    K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1
Other DBs
COG: COG0515
GO: 0004676
Genes
HSA: 5170(PDPK1)
PTR: 112205915 467875(PDPK1)
PPS: 100971139 100981220(PDPK1)
GGO: 101147096(PDPK1) 101147811
PON: 100452403(PDPK1) 112129400
PPYG: 129015996(PDPK1) 129015998
NLE: 100593010 115831277
SSYN: 129462537 129462538
MCC: 697523(PDPK1)
MCF: 101866379(PDPK1)
MNI: 105485792(PDPK1)
CSAB: 103247598(PDPK1)
CATY: 105573290(PDPK1)
PANU: 101006436(PDPK1)
MLEU: 105541556(PDPK1)
RRO: 104661825 104682713(PDPK1)
TFN: 117083793
CANG: 105501470(PDPK1)
CJC: 100389944(PDPK1)
SBQ: 101032521(PDPK1)
CIMI: 108291018(PDPK1)
ANAN: 105709815(PDPK1)
CSYR: 103265584(PDPK1)
MMUR: 105859676(PDPK1)
LCAT: 123631504(PDPK1)
PCOQ: 105813132(PDPK1)
OGA: 100950210(PDPK1)
MMU: 18607(Pdpk1)
MCAL: 110312395(Pdpk1)
MPAH: 110337888(Pdpk1)
RNO: 81745(Pdpk1)
MCOC: 116078189(Pdpk1)
ANU: 117710000(Pdpk1)
MUN: 110553013(Pdpk1)
CGE: 100772477(Pdpk1)
MAUA: 101835018(Pdpk1)
PROB: 127219578(Pdpk1)
PLEU: 114680796(Pdpk1)
MORG: 121463628(Pdpk1)
MFOT: 126514348
AAMP: 119813044(Pdpk1)
NGI: 103743959(Pdpk1)
HGL: 101709940(Pdpk1)
CPOC: 100735138(Pdpk1)
CCAN: 109689940(Pdpk1)
DORD: 105982143(Pdpk1)
DSP: 122123899(Pdpk1)
PLOP: 125341041(Pdpk1)
NCAR: 124970168
MMMA: 107146703(Pdpk1)
OCU: 100347954
OPI: 101528473(PDPK1)
TUP: 102497633(PDPK1)
GVR: 103585343(PDPK1)
CFA: 479875(PDPK1)
CLUD: 112640520(PDPK1)
VVP: 112909152(PDPK1)
VLG: 121488142(PDPK1)
NPO: 129519211(PDPK1)
AML: 100473305(PDPK1)
UMR: 103668498(PDPK1)
UAH: 113245405(PDPK1)
UAR: 123783746(PDPK1)
ELK: 111156293
LLV: 125090410
MPUF: 101687213(PDPK1)
MNP: 132027002(PDPK1)
MLK: 131819765(PDPK1)
NVS: 122895932(PDPK1)
ORO: 101378353(PDPK1)
EJU: 114215744(PDPK1)
ZCA: 113933750(PDPK1)
MLX: 118021736(PDPK1)
NSU: 110587808(PDPK1)
FCA: 101101686(PDPK1)
PYU: 121019662(PDPK1)
PCOO: 112853361(PDPK1)
PBG: 122471796(PDPK1)
PVIV: 125153912(PDPK1)
LRUF: 124517688
PTG: 102960424(PDPK1)
PPAD: 109278175(PDPK1)
PUC: 125927192
AJU: 106978772
HHV: 120241500(PDPK1)
BTA: 100138102(PDPK1)
BOM: 102264327(PDPK1)
BIU: 109578066(PDPK1)
BBUB: 102410169(PDPK1)
BBIS: 104988870(PDPK1)
CHX: 102184966(PDPK1)
OAS: 101117211(PDPK1)
BTAX: 128060129(PDPK1)
CSUM: 138076201(PDPK1)
ODA: 120873714(PDPK1)
CCAD: 122432732(PDPK1)
MREE: 136160449(PDPK1)
MBEZ: 129545284(PDPK1)
SSC: 100192445(PDPK1)
CFR: 102504617(PDPK1)
CBAI: 105064838(PDPK1)
CDK: 105099701(PDPK1)
VPC: 102528174(PDPK1)
BACU: 103010966(PDPK1)
BMUS: 118880851(PDPK1)
LVE: 103081765(PDPK1)
OOR: 101270868(PDPK1)
DLE: 111185202(PDPK1)
PCAD: 102977392(PDPK1)
PSIU: 116739722(PDPK1)
NASI: 112409350(PDPK1)
ECB: 100630736(PDPK1)
EPZ: 103551639(PDPK1)
EAI: 106826000(PDPK1)
MYB: 102262391(PDPK1)
MYD: 102756818(PDPK1)
MMYO: 118656443(PDPK1)
MLF: 102431196(PDPK1)
MDT: 132232956(PDPK1)
PKL: 118702963(PDPK1)
EFUS: 103290523(PDPK1)
MNA: 107533364(PDPK1)
DRO: 112298319(PDPK1)
SHON: 118985111(PDPK1)
AJM: 119041006(PDPK1)
PDIC: 114495251(PDPK1)
PHAS: 123807097(PDPK1)
MMF: 118642806(PDPK1)
PPAM: 129083615(PDPK1)
HAI: 109385875(PDPK1)
RFQ: 117019434(PDPK1)
PALE: 102896950(PDPK1)
PGIG: 120620273(PDPK1)
PVP: 105303144(PDPK1)
RAY: 107498762(PDPK1)
MJV: 108399811(PDPK1)
TOD: 119242012(PDPK1)
SARA: 101538779 101540891(PDPK1)
SETR: 126001240(PDPK1)
LAV: 100660030(PDPK1)
TMU: 101353040
ETF: 101661509(PDPK1)
DNM: 101432391(PDPK1)
MDO: 100018830(PDPK1)
GAS: 123231496(PDPK1) 123244679
SHR: 100917568(PDPK1)
PCW: 110221981(PDPK1)
TVP: 118830969(PDPK1) 118858781
PBRV: 138176766(PDPK1)
OAA: 100089083(PDPK1)
GGA: 416588(PDPK1)
PCOC: 116237470(PDPK1)
MGP: 100541724(PDPK1)
CJO: 107320588(PDPK1)
TPAI: 128078925(PDPK1)
LMUT: 125700911(PDPK1)
NMEL: 110405647(PDPK1)
APLA: 101798010(PDPK1)
ACYG: 106046039(PDPK1)
CATA: 118256396(PDPK1)
AFUL: 116495306(PDPK1)
TGU: 100227045(PDPK1)
LSR: 110477756(PDPK1)
SCAN: 103817549(PDPK1)
PMOA: 120513308(PDPK1)
OTC: 121334611(PDPK1)
PRUF: 121365851(PDPK1)
GFR: 102032960(PDPK1)
FAB: 101813442(PDPK1)
OMA: 130266833
PHI: 102107665(PDPK1)
PMAJ: 107211032(PDPK1)
CCAE: 111936219(PDPK1)
CCW: 104684909(PDPK1)
CBRC: 103615482(PDPK1)
ACOE: 138118727(PDPK1)
ETL: 114061437(PDPK1)
ZAB: 102075317(PDPK1)
ZLE: 135454163(PDPK1)
ACHL: 103798629(PDPK1)
SVG: 106859269(PDPK1)
MMEA: 130576467(PDPK1)
HRT: 120759544(PDPK1)
SATI: 136368230(PDPK1)
FPG: 101919837(PDPK1)
FCH: 102054066(PDPK1)
CCRI: 104161988(PDPK1)
NNT: 104399731(PDPK1)
SHAB: 115607169(PDPK1)
ACUN: 113485931(PDPK1)
TALA: 104358545(PDPK1)
ACHC: 115335528(PDPK1)
HALD: 104311864(PDPK1)
HLE: 104833677(PDPK1)
AGEN: 126033889
HHAR: 128134545(PDPK1)
GCL: 127022208
CSTI: 104550883(PDPK1)
LDI: 104345816(PDPK1)
MNB: 103779323(PDPK1)
DPUB: 104298820(PDPK1)
PPUS: 135180992(PDPK1)
AVIT: 104276007(PDPK1)
BRHI: 104489831(PDPK1)
EGZ: 104131301(PDPK1)
NNI: 104015160(PDPK1)
PCAO: 104039773(PDPK1)
PADL: 103913922(PDPK1)
AFOR: 103904950(PDPK1)
FGA: 104082750(PDPK1)
GSTE: 104254735(PDPK1)
CLV: 102092469(PDPK1)
MUI: 104545013(PDPK1)
PGUU: 104463698(PDPK1)
PLET: 104628859(PDPK1)
EHS: 104514725(PDPK1)
CMAC: 104480561(PDPK1)
CUCA: 104065039(PDPK1)
TEO: 104370151(PDPK1)
BREG: 104630150(PDPK1)
OHA: 104336152(PDPK1)
ACAR: 104523875(PDPK1)
CPEA: 104393099(PDPK1)
CVF: 104295102(PDPK1)
RTD: 128914374(PDPK1)
AAM: 106486128(PDPK1)
AROW: 112975524(PDPK1)
NPD: 112959758(PDPK1)
TGT: 104574754(PDPK1)
DNE: 112991425(PDPK1)
SCAM: 104139059(PDPK1)
ASN: 102383992(PDPK1)
AMJ: 102575851(PDPK1)
CPOO: 109314582(PDPK1)
GGN: 109294444(PDPK1)
PSS: 102460679(PDPK1)
CMY: 102946336(PDPK1)
CCAY: 125643573(PDPK1)
DCC: 119863008(PDPK1)
CPIC: 101943277(PDPK1)
TST: 117883619(PDPK1)
CABI: 116830167(PDPK1)
MRV: 120374088(PDPK1)
ACS: 100559955(pdpk1)
ASAO: 132781891(PDPK1)
PVT: 110085010(PDPK1)
SUND: 121914625(PDPK1)
PBI: 103067411(PDPK1)
PMUR: 107302608(PDPK1)
CTIG: 120313560(PDPK1)
TSR: 106552820(PDPK1)
PGUT: 117667344(PDPK1)
APRI: 131185126(PDPK1)
PTEX: 113438588(PDPK1)
NSS: 113422560(PDPK1)
VKO: 123034806(PDPK1)
PMUA: 114584125(PDPK1)
PRAF: 128401414(PDPK1)
ZVI: 118092862(PDPK1)
HCG: 128336671(PDPK1)
GJA: 107106228(PDPK1)
STOW: 125431736(PDPK1)
EMC: 129340664(PDPK1)
XLA: 108703133(pdpk1.S) 444529(pdpk1.L)
XTR: 779524(pdpk1)
NPR: 108794718(PDPK1)
RTEM: 120943428(PDPK1)
BBUF: 121007440(PDPK1)
BGAR: 122944762(PDPK1)
MUO: 115475789(PDPK1)
GSH: 117345537(PDPK1)
DRE: 403000(pdpk1b) 768202(pdpk1a)
PTET: 122329752(pdpk1b) 122341500(pdpk1a)
LROH: 127155812(pdpk1b) 127157032(pdpk1a)
OMC: 131532993(pdpk1b) 131536992(pdpk1a)
PPRM: 120479594(pdpk1b) 120489359(pdpk1a)
RKG: 130076607(pdpk1a) 130103344(pdpk1b)
MAMB: 125257763(pdpk1b) 125270192(pdpk1a)
CERY: 137014146(pdpk1b) 137017817(pdpk1a)
TROS: 130547188(pdpk1b) 130562084(pdpk1a)
TDW: 130413523(pdpk1b) 130426641(pdpk1a)
MANU: 129426111(pdpk1b) 129431830(pdpk1a)
IPU: 108257355(pdpk1a) 108264442(pdpk1b)
IFU: 128600260(pdpk1a) 128604408(pdpk1b)
SMEO: 124375995(pdpk1a) 124384291(pdpk1b)
TFD: 113652089(pdpk1b) 113661748(pdpk1a)
TVC: 132846426(pdpk1b) 132863980(pdpk1a)
TRN: 134310921(pdpk1b)
AMEX: 103022926(pdpk1a) 103033547(pdpk1b)
CMAO: 118805760(pdpk1a) 118822345(pdpk1b)
CHAR: 105910229(pdpk1b)
TRU: 101076701(pdpk1)
TFS: 130526428(pdpk1b)
LCO: 104923215(pdpk1)
NCC: 104946334(pdpk1)
TBEN: 117473661(pdpk1b)
CGOB: 115024330(pdpk1)
PGEO: 117464693(pdpk1b)
GACU: 117545078(pdpk1b)
EMAC: 134870788(pdpk1b)
ELY: 117247415(pdpk1b)
EFO: 125880414(pdpk1b)
PLEP: 121958807(pdpk1b)
SLUC: 116044291(pdpk1b)
ECRA: 117937188(pdpk1b)
ESP: 116671370(pdpk1)
PFLV: 114548419(pdpk1)
GAT: 120818979(pdpk1b)
PPUG: 119213165(pdpk1b)
AFB: 129091729(pdpk1b)
CLUM: 117748707(pdpk1b)
PSWI: 130203227(pdpk1b)
CANA: 137789268(pdpk1b)
MSAM: 119915538(pdpk1b)
SCHU: 122868056(pdpk1b)
CUD: 121528338(pdpk1b)
ALAT: 119009774(pdpk1b)
ASTR: 137588191(pdpk1b)
MZE: 101463568(pdpk1)
ONL: 100696321(pdpk1)
OAU: 116319876(pdpk1b)
OLA: 101164682(pdpk1)
OML: 112154440(pdpk1b)
CSAI: 133418928(pdpk1b)
XMA: 102230385(pdpk1)
XCO: 114157111(pdpk1)
XHE: 116727073(pdpk1)
PRET: 103481066(pdpk1)
PLAI: 106936097 106940164(pdpk1)
PPRL: 129377784(pdpk1b)
CVG: 107089553(pdpk1)
CTUL: 119793747(pdpk1b)
GMU: 124875685(pdpk1b)
NFU: 107388035(pdpk1)
KMR: 108237196(pdpk1b)
ALIM: 106517371(pdpk1)
NWH: 119423421(pdpk1b)
AOCE: 111584920(pdpk1)
EJA: 138202093(pdpk1b)
MCEP: 125022245(pdpk1b)
CSEM: 103381714(pdpk1)
POV: 109626882(pdpk1)
SSEN: 122758972(pdpk1b)
HHIP: 117753368(pdpk1b)
HSP: 118100245(pdpk1b)
PPLT: 128426619(pdpk1b)
SMAU: 118287022(pdpk1b)
LCF: 108886759(pdpk1b)
SDU: 111220410(pdpk1)
SLAL: 111658643(pdpk1)
XGL: 120794611(pdpk1b)
HCQ: 109530196(pdpk1)
SSCV: 125991102(pdpk1b)
SBIA: 133495847(pdpk1b)
PEE: 133418280(pdpk1b)
PTAO: 133469481(pdpk1b)
BPEC: 110159640(pdpk1)
MALB: 109963581(pdpk1)
BSPL: 114845715(pdpk1b)
SJO: 128381694(pdpk1b)
OTW: 112223683(pdpk1b) 112224117
OMY: 110486327(pdpk1a) 110491592(pdpk1b) 110498855
OGO: 124039893 124048341(pdpk1b)
OKE: 118357632 118365314(pdpk1a) 118365343 118371044(pdpk1b)
ELS: 105021296(pdpk1)
SFM: 108923949(pdpk1)
AANG: 118217213 118220815(pdpk1b)
LOC: 102691100(pdpk1)
PSPA: 121300983(pdpk1b) 121330948
PSEX: 120542912
LCM: 102346160(PDPK1)
CMK: 103186641(pdpk1a)
CPLA: 122560705
HOC: 132825446
LERI: 129706787
PMRN: 116949603(PDPK1)
LRJ: 133347045(PDPK1)
BFO: 118428892
BBEL: 109462798
SPU: 581490
APLC: 110979717
ARUN: 117292240
AJC: 117100611
SKO: 100377375
DME: Dmel_CG1210(Pdk1)
DER: 6544057
DSE: 6610130
DSI: Dsimw501_GD13545(Dsim_GD13545)
DSR: 110184506
DPO: 6899962
DPE: 6601047
DMN: 108152238
DWI: 6643143
DGR: 6556798
DAZ: 108614362
DNV: 108657900
DHE: 111597413
DVI: 6622672
CCAT: 101449813
BOD: 106619258
BDR: 105225577
RZE: 108379430
AOQ: 129242940
TDA: 119681125
SCAC: 106094275
LCQ: 111687838
LSQ: 119605901
GFS: 119632139
ECOE: 129946054
CLON: 129613550
HIS: 119650179
AGA: 1281703
ACOZ: 120947585
AARA: 120897320
AMER: 121588870
ASTE: 118505196
AFUN: 125764085
AMOU: 128308892
AALI: 118458146
CNS: 116351052
BCOO: 119083335
LLL: 129793648
PPAP: 129804517
AME: 410732
ACER: 107994871
ALAB: 122718631
ADR: 102672095
AFLR: 100863943
BIM: 100742861
BBIF: 117204525
BVK: 117235193
BVAN: 117153635
BHUN: 126868462
BTER: 100644761
BAFF: 126918014
BPYO: 122569560
BPAS: 132916389
FVI: 122530198
CCAL: 108629641
OBB: 114875379
OLG: 117603960
NMEA: 116430517
CGIG: 122395239
SOC: 105202789
MPHA: 105829835
AEC: 105144913
ACEP: 105620300
PBAR: 105426049
VEM: 105561076
HST: 105186906
DQU: 106741613
CFO: 105258854
FEX: 115234796
LHU: 105672857(Pdk1)
PGC: 109859788
OBO: 105275845
PCF: 106787987
PFUC: 122517462
VPS: 122628270
VCRB: 124421978
VVE: 124954020
NVI: 100115534
CSOL: 105360683
TPRE: 106652644
LHT: 122508511
LBD: 127277560
MDL: 103579399
CGLO: 123273679
FAS: 105271096
DAM: 107042808
AGIF: 122850106
CINS: 118065393
VCAN: 122408115
CCIN: 107264915
DSM: 124413580
NPT: 124221660(Pdk1)
NFB: 124184663
NLO: 107223053
NVG: 124306726
AROA: 105692966
TCA: 661920
DPA: 109542293
SOY: 115885962
AGRG: 126739654
ATD: 109596747
CSET: 123321114
AGB: 108913723
LDC: 111513594
DVV: 114325167
NVL: 108564485
APLN: 108742633
PPYR: 116172989
OTU: 111414770
BMOR: 101746352
BMAN: 114249556
MSEX: 115451287
BANY: 112044972
MJU: 123867949
NIQ: 126774546
VCD: 124536484
MCIX: 123659698
PMAC: 106708826
PPOT: 106099928
PXU: 106121263
BPHI: 137919578(Pdk1)
PRAP: 111003009
PBX: 123709279
PNAP: 125048607
CCRC: 123694255
LSIN: 126970152
AAGE: 121738312
HZE: 124635413
TNL: 113496147
SLIU: 111358786
OFU: 114357704
ATRA: 106135085
GMW: 113521365
PXY: 105381681
PGW: 126372338
LGLY: 125231568
CSTB: 134745128
CCRN: 123297816
API: 100159966
AGS: 114125591
RMD: 113549217
ACOO: 126847387
DVT: 126896723
BTAB: 109039594
DCI: 103505367
CLEC: 106663173
HHAL: 106690061(Pdk1)
HVI: 124354154
FOC: 113204003
TPAL: 117651310
ZNE: 110834503
CSEC: 111867624
SGRE: 126354876
BROR: 134542679
IEL: 124166111
FCD: 110848044
DMK: 116919464
DPZ: 124344159
AFRA: 136039972
PVM: 113830594
PJA: 122258341
PCHN: 125043571
PMOO: 119586023
HAME: 121872566
PCLA: 123759444(Pdk1)
CQD: 128698231
PTRU: 123505229
MNZ: 135208812
MRJ: 136845789(Pdk1)
HAZT: 108672262
EAF: 111713315
LSM: 121127823
TCF: 131886896
DSV: 119453106
RSAN: 119400031
RMP: 119180141
VDE: 111245450
VJA: 111268520
DPTE: 113790838
DFR: 124496663
CSCU: 111640149
CVS: 136986131(Pdk1)
PTEP: 107438749
ABRU: 129957018
UDV: 129223362
SDM: 118201474
LPOL: 106470789
PMEO: 129580807
CEL: CELE_H42K12.1(pdk-1)
CBR: CBG_08059(Cbr-pdk-1) CBG_15618
BMY: BM_BM4698(Bma-pdk-1)
TSP: Tsp_11250
PVUL: 126810732
PCAN: 112575444
BGT: 106052819
GAE: 121378389
HRF: 124110633
HRJ: 124275069
HASI: 137283391
CRG: 105331792
CANU: 128166562
CVN: 111119108
OED: 125671173
MYI: 110450565
PMAX: 117325522
AIRR: 138322927
MCAF: 127709043
MMER: 123563462
RPHI: 132738034
MAEA: 128211568
OBI: 106872777
OSN: 115215594
LJP: 135466717
LAK: 106155605
EGL: EGR_10565
LLON: 135486025
NVE: 5520244
EPA: 110253154
ATEN: 116298865
ADF: 107355943
AMIL: 114957652
MCAZ: 138059599
MFOO: 137970096
PDAM: 113667682
SPIS: 111325453
DGT: 114519485
XEN: 124449268
HMG: 100200349
HSY: 130649074
RES: 135691717
AQU: 100634673
ATH: AT3G10540 AT5G04510(PDK1)
THJ: 104816450
CPAP: 110809121
CIT: 102606895
PVY: 116108603
MINC: 123193105
TCC: 18586587
EGR: 104421748
PVU: 137828705
VRA: 106771878
VAR: 108321979
VUN: 114190166
VUM: 124839007
CCAJ: 109804760
APRC: 113870900
MTR: 25484865
TPRA: 123917943
CAM: 101506953
VVO: 131643807
LJA: 130718170
ADU: 107466702
AIP: 107618205
FVE: 101302872
AANS: 126802089
RCN: 112182237
PPER: 18787083
PMUM: 103332290
PAVI: 110765519
PDUL: 117619089
ZJU: 107413089
MNT: 21388684
CSAV: 115706067
CSV: 101212874
CMO: 103489417
BHJ: 120081895
MCHA: 111010127
RCU: 8263596
MEAN: 126660540
JCU: 105648420
CAVE: 132164552
AGLU: 133879725
QSU: 112026659
QLO: 115986603
TWL: 119990053
VVI: 100264394
SLY: 101262698 544184(Pdk1)
ECAD: 122604804
LSV: 111911126
RVL: 131319473
BVG: 104884292
SOE: 110803688
ATRI: 130818184
MOF: 131166378
OSA: 4324953
OBR: 102704941
OGL: 127760547
BDI: 100835821
ATS: 109758876
TUA: 125545410
LPER: 127344209
SBI: 8060994
ZMA: 103650947
SITA: 101769773
SVS: 117857682
PHAI: 112892113
PDA: 103702739
EGU: 105036581
NCOL: 116264059
ATR: 18424293
CJF: 131076613
PPP: 112277681
MNG: MNEG_8513
APRO: F751_4489
SCE: YDR466W(PKH3) YDR490C(PKH1) YOL100W(PKH2)
KMX: KLMA_20554(PKH3) KLMA_80265(PKH1)
CGR: 2888021(PKH2) 2888974(GVI51_I07337) 2890437(GVI51_K06325)
NCS: NCAS_0A07990(NCAS0A07990) NCAS_0C04940(NCAS0C04940)
NDI: NDAI_0G04290(NDAI0G04290) NDAI_0H01020(NDAI0H01020)
TPF: TPHA_0D02740(TPHA0D02740) TPHA_0P01050(TPHA0P01050)
TBL: TBLA_0B02310(TBLA0B02310) TBLA_0B08250(TBLA0B08250) TBLA_0E02790(TBLA0E02790)
TDL: TDEL_0A04580(TDEL0A04580) TDEL_0D05320(TDEL0D05320)
KAF: KAFR_0C01440(KAFR0C01440) KAFR_0K02490(KAFR0K02490)
KNG: KNAG_0C06060(KNAG0C06060) KNAG_0K00680(KNAG0K00680)
PIC: PICST_83871(PKH2) PICST_924(PKH1)
LEL: PVL30_003097(PKH1) PVL30_005382(PKH3)
LBG: 92205292(LODBEIA_P00960) 92206510(LODBEIA_P13140)
CTEN: 18249337(PKH3)
YLI: 2907363(YALI2_C00228g)
SLB: AWJ20_4178(PKH2)
NCR: NCU03571(stk-23)
NTE: NEUTE1DRAFT130853(NEUTE1DRAFT_130853)
SMP: 10810002(SMAC4_07806)
PBEL: QC761_604370(PKH1)
PPSD: QC762_604370(PKH1)
PPSP: QC763_604370(PKH1)
PPSA: QC764_604370(PKH1)
MGR: MGG_01795
PGRI: PgNI_03694
SSCK: SPSK_08534
TATV: 25776088(TrAtP1_003824)
TASP: 36609428(TrAFT101_007454)
MAW: 90962489(ssr3_1)
MAJ: MAA_02689
MBRN: 26241811(ksg1)
CMT: CCM_07467
PLJ: 28888772(PLICBS_009205)
PTKZ: JDV02_005899(PKH1)
CDET: 87943018(CDEST_06515)
MBE: MBM_07372
ALUC: AKAW2_10727A(PKH3)
ACHE: ACHE_20264S(PKH3)
APUU: APUU_30405S(PKH3)
CPW: 9694247(PKH3)
ABE: ARB_00106
TVE: TRV_06647
PNO: SNOG_06367(SNOG_06366)
PTE: PTT_09636
PTRR: 6339691(PtrM4_020290)
SPO: 2539517(ksg1)
SOM: SOMG_04866(ksg1)
CNE: CNC05250
CNB: CNBC1920
CDEU: CNBG_3559
CDEP: 91085013(L203_100799)
KMG: 30165484(I203_101619)
KNE: 92178038(IAR55_000779)
TASA: A1Q1_06053
CCAC: CcaHIS019_0705200(PKH1)
ABP: AGABI1DRAFT36927(AGABI1DRAFT_36927)
ABV: AGABI2DRAFT68901(AGABI2DRAFT_68901)
MGL: MGL_1245
MRT: MRET_2899
DDI: DDB_G0281471(pdkA) DDB_G0284489(pdkB)
DFA: DFA_05743(pdkB) DFA_09142(pdkA)
BLAC: 94348144(CCR75_004387)
 » show all
Reference
PMID:9094314
  Authors
Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, Reese CB, Cohen P
  Title
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.
  Journal
Curr Biol 7:261-9 (1997)
DOI:10.1016/S0960-9822(06)00122-9
  Sequence
[hsa:5170]
Reference
PMID:9445476
  Authors
Pullen N, Dennis PB, Andjelkovic M, Dufner A, Kozma SC, Hemmings BA, Thomas G.
  Title
Phosphorylation and activation of p70s6k by PDK1.
  Journal
Science 279:707-10 (1998)
DOI:10.1126/science.279.5351.707
  Sequence
[hsa:5170]
Reference
  Authors
Casamayor A, Torrance PD, Kobayashi T, Thorner J, Alessi DR
  Title
Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast.
  Journal
Curr Biol 9:186-97 (1999)
DOI:10.1016/S0960-9822(99)80088-8
  Sequence
Reference
  Authors
Inagaki M, Schmelzle T, Yamaguchi K, Irie K, Hall MN, Matsumoto K
  Title
PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast.
  Journal
Mol Cell Biol 19:8344-52 (1999)
DOI:10.1128/MCB.19.12.8344
  Sequence
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