Odobenus rosmarus divergens (Pacific walrus): 101369340
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Entry
101369340 CDS
T05148
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
oro
Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro00140
Steroid hormone biosynthesis
oro00980
Metabolism of xenobiotics by cytochrome P450
oro01100
Metabolic pathways
oro05204
Chemical carcinogenesis - DNA adducts
Module
oro_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
oro00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
101369340 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
101369340 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
101369340 (HSD11B1)
Enzymes [BR:
oro01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
101369340 (HSD11B1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
Shikimate_DH
NAD_binding_2
2-Hacid_dh_C
Pyr_redox_3
Motif
Other DBs
NCBI-GeneID:
101369340
NCBI-ProteinID:
XP_004408826
UniProt:
A0A2U3WJ27
LinkDB
All DBs
Position
Unknown
AA seq
292 aa
AA seq
DB search
MAFMKKYLPPILGIFLAYYYYSANEEFRPEMLQGKKVIVTGASKGIGEQMAYHLAKMGAH
VVVTARSKETLKKVVSHCLELGAASAHYIAGSMENVTFAEQFVAQAGKLMGGLDMLILNH
ITNTSLNLFSGDIHLVRRNMEVNFLSYVVLSVAALPMLKQSNGSIVVVSSKAGKMASPLV
APYSASKFALDGFFSSIRMEHSVTKVNVSITLCILGLINTDTAMKAVSGILNIDASPKEE
CALEIIKGGALRQEEVYYDNSVWTDLLLGNPGRKILEFLSLRSYSLDKFINN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctcccccccattctggggatcttcttggcctactactac
tattctgcgaatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaggggatcggagaacagatggcctatcatctggcaaaaatgggagcccat
gtggtggtgacggcaaggtctaaagaaactctaaagaaggtggtatcccactgcctggag
cttggagcagcctcagcgcactacattgctggctccatggagaatgtgaccttcgcagag
caatttgttgcccaagctgggaagctcatggggggactagacatgctcattctcaaccac
atcaccaacacttccttgaatctgtttagtggtgatatccacctcgtgcgcagaaacatg
gaagtcaacttcctcagttacgtggtcctgagcgttgctgccttgcccatgctgaagcag
agcaatgggagcattgttgtcgtctcctcgaaggctgggaaaatggctagtccacttgtt
gcaccctattctgcaagcaagtttgctctggatgggtttttctcctctatcaggatggaa
cattcagtgaccaaggtcaatgtctcgatcactctctgtatcctcggcctcataaacaca
gacacagccatgaaggccgtttctgggatactcaacatcgatgcgtctccgaaggaagaa
tgtgccctggagatcatcaaagggggagctctgcgtcaagaggaagtgtactatgacaac
tcagtctggacagatctcctgctgggaaacccagggaggaagatcctggaattcttgtcc
ttaagaagttatagtttggacaaatttataaacaactaa
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