Pteropus alecto (black flying fox): 102884281
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Entry
102884281 CDS
T02993
Gene name
MDM2
Definition
(RefSeq) E3 ubiquitin-protein ligase Mdm2
KO
K06643
E3 ubiquitin-protein ligase Mdm2 [EC:
2.3.2.27
]
Organism
pale
Pteropus alecto (black flying fox)
Pathway
pale01522
Endocrine resistance
pale01524
Platinum drug resistance
pale04068
FoxO signaling pathway
pale04110
Cell cycle
pale04115
p53 signaling pathway
pale04120
Ubiquitin mediated proteolysis
pale04144
Endocytosis
pale04151
PI3K-Akt signaling pathway
pale04218
Cellular senescence
pale04625
C-type lectin receptor signaling pathway
pale04919
Thyroid hormone signaling pathway
pale05163
Human cytomegalovirus infection
pale05165
Human papillomavirus infection
pale05169
Epstein-Barr virus infection
pale05200
Pathways in cancer
pale05202
Transcriptional misregulation in cancer
pale05203
Viral carcinogenesis
pale05205
Proteoglycans in cancer
pale05206
MicroRNAs in cancer
pale05214
Glioma
pale05215
Prostate cancer
pale05218
Melanoma
pale05219
Bladder cancer
pale05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
pale00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102884281 (MDM2)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
102884281 (MDM2)
04151 PI3K-Akt signaling pathway
102884281 (MDM2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102884281 (MDM2)
09143 Cell growth and death
04110 Cell cycle
102884281 (MDM2)
04115 p53 signaling pathway
102884281 (MDM2)
04218 Cellular senescence
102884281 (MDM2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
102884281 (MDM2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
102884281 (MDM2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102884281 (MDM2)
05202 Transcriptional misregulation in cancer
102884281 (MDM2)
05206 MicroRNAs in cancer
102884281 (MDM2)
05205 Proteoglycans in cancer
102884281 (MDM2)
05203 Viral carcinogenesis
102884281 (MDM2)
09162 Cancer: specific types
05214 Glioma
102884281 (MDM2)
05220 Chronic myeloid leukemia
102884281 (MDM2)
05218 Melanoma
102884281 (MDM2)
05219 Bladder cancer
102884281 (MDM2)
05215 Prostate cancer
102884281 (MDM2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
102884281 (MDM2)
05169 Epstein-Barr virus infection
102884281 (MDM2)
05165 Human papillomavirus infection
102884281 (MDM2)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102884281 (MDM2)
01522 Endocrine resistance
102884281 (MDM2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pale04131
]
102884281 (MDM2)
04121 Ubiquitin system [BR:
pale04121
]
102884281 (MDM2)
Enzymes [BR:
pale01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
102884281 (MDM2)
Membrane trafficking [BR:
pale04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
102884281 (MDM2)
Ubiquitin system [BR:
pale04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
MDM2/MDM4 proteins
102884281 (MDM2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
zf-C3HC4_3
SWIB
zf-RanBP
zf-RING_2
DUF1229
zf-FPG_IleRS
Motif
Other DBs
NCBI-GeneID:
102884281
NCBI-ProteinID:
XP_006923785
LinkDB
All DBs
Position
Unknown
AA seq
492 aa
AA seq
DB search
MCNTSMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY
IMNKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQEPSDSGI
PVSENRCHLESGSDEKDPVQELQEEKPSSSDLVSRPSASSRRRTISETEDNSDELPGERQ
RKRHKSDSISFSFDESLALCVIREIRCERNSSSESTGTSSNPDLDAGVSEHSGDWLDQDS
VSDRFSVEFEVESFNSEDYNLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEDDPEISLA
DYWKCTSCSEMNPPLPPHCNRCWALRENWLPEDKRKEKGKMDEKTELENSVQVEEGFDVP
DCKKNPTVYDSRESCIEENDEKITQASQSQESEDYSQPSTSSSIIYSSQEDVKELEKEET
QDKEESVESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCR
QPIQMIVLTYFS
NT seq
1479 nt
NT seq
+upstream
nt +downstream
nt
atgtgcaataccagcatgtctgtgtctactgatggtgctgtaagcacctcacagattcca
gcttcagagcaagagaccctggttagaccaaagccattacttttgaagttgttgaaatct
gttggtgcacaaaaagacacttacactatgaaagaggttatattttatcttggccagtat
attatgaacaaacgattatatgatgagaagcaacagcatattgtatattgttcaaatgat
cttctaggggatttgtttggagtgccaagcttctctgtgaaagaacacaggaaaatatat
acaatgatctacagaaacttggtagtagtcaatcagcaggaaccatcagattcaggcata
cctgtgagtgaaaacaggtgtcatcttgaaagtgggagtgatgaaaaggaccctgtgcaa
gagctacaagaagaaaaaccttcatcttcagatttggtttctagaccatctgcctcatct
agaaggagaacgattagtgagacagaagacaattcagatgaattacctggtgaacgacaa
agaaagcgccacaaatctgatagtatttccttttcctttgatgaaagccttgctctgtgt
gtaataagggagatacgttgtgaaagaaacagtagcagtgaatcaacagggacttcatca
aatccggatctcgatgctggtgtcagtgaacattcaggtgattggttggatcaggattca
gtttcagatcgattcagtgtagaatttgaagttgagtctttcaattcggaagattataac
cttagtgaagaaggacaagaactctcagatgaagatgatgaggtatatcaagttaccgtg
tatcaggcaggggaaagtgatacggattcatttgaagacgaccctgaaatctccttagct
gactattggaagtgtacttcatgcagtgaaatgaatcctccccttccaccacattgcaac
agatgctgggcccttcgtgagaattggcttcctgaagacaaaaggaaagaaaaagggaaa
atggatgagaaaactgaacttgaaaactcagtacaagtagaagagggctttgatgtccct
gattgtaaaaaaaatcctacagtgtatgattcccgagaatcatgtattgaggaaaatgat
gaaaagatcacacaagcctcccaatcccaagaaagtgaagactattctcagccatcaact
tctagtagcatcatttatagcagccaagaagatgtcaaagagttagagaaagaagaaaca
caagacaaagaagaaagtgtggagtctagttttccacttaatgccatcgaaccttgtgtg
atttgccaaggtcgacctaaaaatggttgcatcgtccatggcaaaacaggacatcttatg
gcatgttttacatgtgcaaagaagctaaagaaaaggaacaagccctgcccagtatgtaga
caaccaattcaaatgatcgtgttaacttatttctcctag
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