Phascolarctos cinereus (koala): 110206438
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Entry
110206438 CDS
T05867
Gene name
ALK
Definition
(RefSeq) LOW QUALITY PROTEIN: ALK tyrosine kinase receptor
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw05200
Pathways in cancer
pcw05223
Non-small cell lung cancer
pcw05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110206438 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110206438 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
110206438 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110206438 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pcw04090
]
110206438 (ALK)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110206438 (ALK)
Protein kinases [BR:
pcw01001
]
Receptor tyrosine kinases (RTK)
ALK family
110206438 (ALK)
CD molecules [BR:
pcw04090
]
Proteins
110206438 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
MAM
Gly_rich
Ldl_recept_a
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
110206438
NCBI-ProteinID:
XP_020839426
UniProt:
A0A6P5K3N3
LinkDB
All DBs
Position
Unknown
AA seq
1651 aa
AA seq
DB search
MGAPRMFPSAVLPPLLLVLLVTIPRSLSLDPFGFSAGSSPTTEQPQTQQQQPGQQQPQQQ
REPLSYSRLQRKSLAVDFIVPSLFRIYARDLLLLLPSVPGTSLPEARSSLALDCSPLLLL
LLRRQGATRTAALPHLPPGGRVLSKVLKGGSVXKLRRAKQLVLEVGEEAILEGCTGTSTS
PPEQAAVATAGMLEFNLTEMFSWWVRHGEGRLRIRLMPEKKDSLPGREVRLSAAIRASQP
RLLFQIIRKAPSSLESSTKVLAFTPEPFIWNLTWIMKDSPPFLSQRSRYGFECNFDFPCE
LEYSPPLQEDGNHYWSWRHITSEEASQMNLFSGGTAVIHSEDMPKGSFLLLNTSENTKHT
ILSPWMRSNSEHCTMQVSVYRDLQTSGRYMAQLLPHNEARREILLVPNPETHGWTVLHGR
IGYLQSPFRVSLEYISSANGSLSLVDSLSLKNCSEGMPPISKMALKSSFTCWNGTAIHLG
QACNFQRDCSEGEDEGELCKKLPAGFYCDFEDGDCGWIQGMAMPHTPQWQVGILEDAPFP
NYQGYAMLLNTSKASPAETVVLTSIMFPAPMKNSPCELQFSWLIHGVLEGNITLMLVENK
TGKEQSRTIWYFANSGDLGIWHRMVLPLPDVSDRFWLQIVTWWEEDSGAIIAFDNISLSL
DCYLTIHGEEIISRDDAPNSRNLFESIYKKSLQEPRLQETAHGENLNFDPTVHWLFTTCG
ASGPQGPTQTQCNNAYRNSNLSVVVGSEGALKGVQIWKVPATDTYSISGYGAAGGKGGKN
TMMRSHGVSVLGVFDLEKDDVLYILVGQQGGDACPSTNEIIQKVCIGENNVIEEEIRANQ
SVNEWAGGGGGGGGATYIFKMKNGIPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLG
LNGISGAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGFGGGGGGCS
SGGGGGGYIGGNAAVNNDPEVDGEDGVSFISPLGILYTPALKVMEGHGEVNIKLYLNCSH
CEVDECHIDPESHKVICFCEHGTVLAEDGVSCIVSPTSEPHLPLSLILSVVTSALVAALV
LAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTTSISDLK
EVPRKNISLIRGLGHGAFGEVYEGQVSGSPSDPSPLQVAVKTLPEVCSEQDELDFLMEAL
IISKFNHQNIVRCIGVSLQALPRFILLELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHV
ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA
MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD
PPKNCPGPVYRIMTQCWQHLPEDRPNFATILERIEYCTQDPDVVNTALPIEYGPVTEEEE
KVPVRPEDPDRIPPLLVSPQQEKKEDVCPPSVPPPLSTTSSGKPVKKAMALEPPVRVTRG
THVEGGHVNMAYSQSNPPTELHKGRGSRNKPTSLWNPTYGSWFTEKSATKNNPLTEKEQP
ERGKSGPEGQSTAGPPSVVPGRLPGSSLLLEPSSLTATMTEVPLFRLRHFPCGNVHYGYQ
QQGLPLEATPAAGSYGDSVPRNPSSVTQPGP
NT seq
4956 nt
NT seq
+upstream
nt +downstream
nt
atgggagcacccagaatgttcccatcggcggtgctgccacctctgctgttagtattgctg
gttacaatccctcggtcactgagcttggacccttttggcttctccgctggcagttcccca
acgacggagcaaccccagacccaacagcagcagcccggacagcagcagcctcagcagcaa
cgcgagccacttagctactcccggctccagaggaagagcctggctgtggacttcattgtg
ccctctctattcaggatctatgcccgggacctgctactgttgcttccatcggtaccgggt
accagcctacccgaggcgcgcagttctctggcgctggactgctcgcccctgctgctgctg
cttctgaggcgtcagggtgccaccaggactgctgctctgccccacctaccacccggagga
cgagtactgtccaaggttctgaagggtggctctgtgnnaaagctccgcagggccaagcag
ctggtgctggaagtgggcgaggaggcgatcctggagggctgcacgggcacctccactagt
cctccggagcaggcggctgtggccacggcaggaatgctagagttcaacctcacagagatg
ttcagttggtgggttcgccacggcgaagggcggctgcggatccgcctgatgccggagaag
aaggactctttgccaggcagagaagtaagactgtctgcagcaataagagcctcccagcct
cgtctacttttccaaatcataaggaaggctccaagctccctggaatcttctacaaaggtc
cttgctttcactcccgaaccctttatctggaacctaacatggatcatgaaagactctccc
cctttcctctctcaacgtagccgctatggttttgagtgcaactttgatttcccctgtgag
ctggagtattcaccacctctgcaggaagatggaaaccactactggtcttggcgccacatc
acttctgaggaggcttcccaaatgaacctgttcagtggtggcactgcagtgattcattct
gaggacatgccgaaaggttctttccttctcctcaatacatctgaaaacaccaaacatact
attctgagcccttggatgaggagcaacagtgaacactgcaccatgcaagtgtctgtatac
agggacctccaaacttcggggagatacatggcccaactcctaccacacaatgaagctagg
agagagatccttctggttccaaatccagagacacatggctggacagtgctccatgggaga
attggatacctacagagtcctttccgggtctccttggaatacatctcaagtgccaatggg
agcctatctctggtagattctttgtctctgaagaactgcagtgaagggatgccacctatc
tccaaaatggccctgaagagctccttcacctgctggaatggaacagccattcacctgggc
caggcttgcaactttcagagagactgctctgagggcgaagacgagggagaattgtgcaaa
aaactcccagctggattttattgtgactttgaggatggagactgtggctggattcaaggc
atggccatgccccatactccccagtggcaggttgggatcttggaggatgccccatttcca
aattaccaaggctacgcaatgctgcttaacactagcaaggctagcccagcagaaactgtg
gtactgaccagcatcatgtttcctgcaccaatgaagaactctccttgtgagctccaattc
tcatggctcatccacggagtcttggaaggaaacattaccctgatgctggtggagaacaaa
actgggaaggagcaaagccggactatctggtactttgccaacagtggagatttgggcatt
tggcatcggatggtcttacctcttcctgatgtgtcagacagattctggctccagattgtc
acatggtgggaggaagactcaggcgccatcattgcttttgacaacatctccctcagcctg
gactgctatcttacaattcatggggaggagataatatcaagggatgacgctcccaattca
agaaacctctttgagagtatctataagaagtcattacaggagccaagattgcaggagact
gcacatggggagaacctcaactttgatccaacagttcactggctgttcaccacatgtgga
gccagcgggccccagggtcctacgcagacccaatgcaacaatgcctacaggaattccaat
ctgagcgtggtagtgggcagcgagggtgccctgaagggtgttcagatctggaaagtgcca
gccaccgacacatacagcatctcaggctatggagcagctggaggtaaaggagggaagaat
actatgatgaggtcccatggtgtgtcagtcttgggagtctttgatctggagaaggatgac
gtcttatacatcttggtgggacagcaagggggagatgcctgccccagtactaatgaaatt
atccagaaggtttgcattggagagaacaatgtgatagaagaagagattcgagccaaccaa
agtgtgaatgagtgggctggaggtggaggaggtgggggtggagcgacctacatttttaag
atgaagaacggaataccagtacctctgatcattgcagccggaggtggtggaagagcctat
ggggccaaaacagatacattccatccagaaagactggaaaataactcctctgttctaggt
ctgaatggcatttctggagccgcaggtggtggaggtggctggaatgataacacttccttg
ctttggtcgggaaaatctttgctggaaggtgctacaggaggacattcctgcccccaggcc
atgaagaagtgggggtgggagacaagagggggtttcggagggggtggaggggggtgctcc
tcaggtggaggaggcggaggatacatagggggtaatgcagctgtgaacaatgaccccgaa
gtggatggggaggatggggtctccttcatcagtccattgggcatcctgtacaccccggct
ctgaaagtgatggagggccatggggaggtgaacatcaaactttacttgaactgcagccac
tgtgaggtggatgaatgccacattgacccagagagccacaaagttatctgtttctgcgag
catggcacagtgctggccgaagacggggtctcctgcatagtgtcacccacctctgagcct
cacctgcctctctctctgatactgtctgttgtgacctctgccctggtggctgccctagtc
ctggcattctctggcatcatgattgtgtaccgcaggaagcaccaggaactccaggcgatg
cagatggaactgcagagccccgagtacaaactgagcaaactgagaacctcaaccatcatg
accgactataaccccaactactgttttgctggcaaaaccacatccatcagtgacctcaag
gaggtgcctcggaaaaacatctccctcattcggggtctgggccatggtgcctttggggag
gtgtatgaaggacaagtgtctggaagccccagtgaccccagccccctgcaggtggcagtt
aagacgcttccagaggtgtgttcagaacaggatgagctggatttcctcatggaagcattg
atcattagcaaattcaaccaccagaacattgttcgctgtattggggtgagcctgcaggcc
ctgccccgatttatcctcctagagctgatggctggaggagacctcaaatccttccttcgg
gagactcgccctcgcccgaaccagccctcctccctggctatgctggacctgctgcacgtg
gctcgtgacattgcctgtggctgtcagtatctggaagaaaaccacttcattcaccgggat
attgctgctaggaactgtctcttgacctgccctggaccaggcagagtggccaaaatcgga
gactttggaatggctcgagacatctacagagcaagctactacaggaagggaggatgtgcc
atgcttccagtcaagtggatgcccccagaggccttcatggaggggatctttacatccaaa
acggatacgtggtccttcggtgtgcttctatgggaaatattctcccttggatacatgcca
tacccaagcaaaagcaatcaggaagttctggagtttgtcaccagtggaggacggatggat
ccacccaaaaattgccctgggcctgtgtaccggatcatgactcagtgctggcagcatctg
cctgaggaccggcccaattttgccaccatcttagagaggattgaatattgtacccaggat
ccagatgtggttaacactgctttgccaatagaatatggtccagtgactgaagaggaagag
aaggtgcccgtgaggccggaagatcctgatagaatacctcctcttttagtctctccacag
caagagaaaaaagaggatgtgtgtccaccatctgttccccctccactgtccaccacttcc
tctggtaagcccgtgaagaaagcaatggctctagagcctccagtccgcgtcaccagaggg
acacacgtagaaggaggacatgtcaacatggcatattctcagtctaatccgccaacagag
ctgcacaaagggcgtggatcaagaaacaaaccaaccagtctttggaaccccacatatggc
tcctggtttacagagaaatctgcaaccaaaaacaatcccctgacagagaaggaacagccc
gagaggggtaaatcagggccagaaggacaatccaccgcggggccacccagtgttgtccct
ggcaggctgccagggtcctccctgctcttggaaccatcttccctgactgccaccatgacg
gaagtgcctctatttaggctccgccacttcccttgtgggaatgtccactacggatatcag
cagcaaggcttacctttggaggccaccccagcagctggcagttatggggactccgttcct
agaaatccgagtagcgtgacccagcctggtccctga
Phascolarctos cinereus (koala): 110218476
Help
Entry
110218476 CDS
T05867
Gene name
EML4
Definition
(RefSeq) echinoderm microtubule-associated protein-like 4 isoform X1
KO
K15420
echinoderm microtubule-associated protein-like 4
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw05200
Pathways in cancer
pcw05223
Non-small cell lung cancer
pcw05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110218476 (EML4)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110218476 (EML4)
09162 Cancer: specific types
05223 Non-small cell lung cancer
110218476 (EML4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
pcw04812
]
110218476 (EML4)
Cytoskeleton proteins [BR:
pcw04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EMAP
110218476 (EML4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
WD40
HELP
Motif
Other DBs
NCBI-GeneID:
110218476
NCBI-ProteinID:
XP_020856878
UniProt:
A0A6P5LG87
LinkDB
All DBs
Position
Unknown
AA seq
997 aa
AA seq
DB search
MEDSLPSLDSLCDTSTLMNFCTDDSISATSTSDVQDRLSALELRVQQQEDEITVLKAALA
DVLRRLTISEDNVVSVKKTASSKGPPALSISCVSNGSGRSRKTNHASPISISRKETFSSA
AKSSTEKKKEKPQGQKEKKEDSHSNDQSPHIRASPSPQPSSQPLQTHRQTQESKSSPPTK
SIKRLPTAEKSLSTWENSDDGHHKLLQPAVTPKLISKIIKNVDKHKDVVINQAKMSTREK
NSQEGEYIKMFMRGRPITMFIPSDVNSYDDIRTELPPEKLKLEWAYGYRGKDCRANVYLL
PTGEIVYFIASVVVLFNYEERTQRHYLSHTDCVKCLAVHPDKMRIATGQIAGVDKDGRPL
QPHVRVWDSVSLATLQVIGLGTFERGVGCLDFSKADSGVHLCVVDDSNDHMLTVWDWQKK
SKRAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWNGNSLTRKQGIFGKYEKPKFV
QCLAFLGNGDVLTGDSGGIILIWNKTTVEPTPGKGPKGVYQIVKQIKAHDGSVFTLCQMR
NGMLLTGGGKDRKVILWDHDLNPEREIEVPEQYGAIRAVAEGKADQFLVGTSRNFILRGT
FNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLEWTRLLDEPGHCA
DFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSKDGTFLAVGSHDNFI
YLYVVSESGRKYSRYGKCAGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRN
RSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYP
CSKPKAPSHKYNGHSSHVTNVSFTHNDSHLISTGGKDMSIIQWRVVEKLSLPQNETPVDI
AITKAPISTNENVLQPNTSTPPPSSQPFSDAAENERMSDSSTPLENDLEQAEEHSEEQSE
GSSEYLAEPSCEEPSNETREEQNESPIPEDQQNSPAS
NT seq
2994 nt
NT seq
+upstream
nt +downstream
nt
atggaagacagcttgcctagtctcgattcactatgtgatacttctacacttatgaacttc
tgcactgatgatagtatctctgctacaagtacttctgatgtccaggatcgtctctctgcc
cttgagttgcgagttcagcaacaagaagatgaaatcacagttctgaaggcagctttggct
gatgtgttaaggcgtcttacaatctctgaagataatgtggtatctgtgaaaaaaacagcc
tcaagtaaaggtccgccagccctttctatttcctgtgtaagcaatggcagtggtagaagc
agaaaaacaaaccatgccagcccgatatcaatatcaagaaaagaaaccttttcatctgct
gctaaaagcagtacagaaaaaaagaaagaaaaaccacaaggacagaaagaaaaaaaagag
gattctcattctaacgatcaaagtccacacattcgagcatcaccttctccccagccctct
tcacagcctctccaaacacacagacaaactcaagaaagcaagagctctcctcccaccaaa
agcataaaacgactacctacagctgaaaaatcacttagtacatgggagaattcggatgat
ggtcatcacaaactattgcagccagctgtaacaccaaaattaatatcaaaaattattaaa
aatgtagacaagcataaagatgttgtcatcaatcaagcaaaaatgtcaactcgtgaaaaa
aacagccaagaaggagaatatatcaaaatgttcatgagaggtcggccaatcacaatgttt
attccttctgatgtcaacagctatgatgacatccgaactgaactgcctcctgagaagctt
aaactggagtgggcatatggctatcggggaaaagattgtcgagctaatgtttaccttctt
cctaccggggaaatagtatatttcatagcttcagtagtagttttgtttaattatgaggaa
agaacccagagacattacctgagtcacacagactgtgtaaaatgccttgctgtacatcct
gacaaaatgaggattgcaactggacagatagctggagtggataaagatggaaggcctcta
cagccccacgtcagagtttgggactcagtcagtctggccacactgcaagttattgggctt
ggaacttttgaacgtggagtgggttgtctggatttttcaaaagcagattcaggtgttcat
ttatgtgtagttgatgactccaatgaccacatgctgactgtgtgggactggcagaaaaaa
tcaaaaagagcagaaatcaagactacaaatgaagttgttctggctgtagaattccatcca
acagatgcaaatacaataataacatgtggcaaatctcatatctttttttggacctggaat
gggaattcactaacaagaaaacaaggaatttttggaaaatatgaaaaacccaaatttgtt
cagtgcttagctttcttggggaatggagatgttcttacaggagactcaggtggaatcatt
cttatatggaacaaaactactgtagaacccacacctgggaaaggacctaaaggtgtatat
caaatagtcaaacaaatcaaagctcatgatggcagtgtcttcacgctttgtcaaatgagg
aatgggatgctactaactggaggagggaaagacagaaaagtaattttgtgggatcatgac
ctaaatcctgaaagagaaatagaggttcctgaacagtatggagcaatccgggcagttgca
gaaggaaaggcagatcaatttttggttggcacatcgagaaattttattctacgaggaacg
tttaatgatggttttcaaatagaagtacagggtcacacagatgaactttggggtcttgct
acacatcccttcaaagacttattattgacctgtgctcaggacaggcaggtgtgcatgtgg
aactcggtggagcacagactggagtggaccagacttttggatgaaccaggacactgtgca
gacttccatccaagtggcacagttgtggccataggaacgcattcaggcaggtggtttgtc
ctggatgcagaaaccagagatctagtttcaatccatacagatggtaatgagcagctctca
gtgatgcgatactcaaaagatggcaccttccttgccgtaggatcccatgacaactttatt
tacctctatgtagtctcagaaagtggaagaaaatatagcagatacggaaaatgcgctgga
cattccagctatattacacaccttgactggtccccagacaacaaatatataatgtccaac
tcaggagactatgagatactatattgggacattccaagtggctgcaaactgatccgaaat
cgttctgactgtaaagacattgactggacaacttacacttgtgtactaggcttccaagtc
tttggagtgtggccagaaggatcagatggaacagatatcaatgctctagtgagatcccat
aaccgaaaagtgatagcagttgctgatgacttttgcaaggtccatctttttcagtatcct
tgttccaagccaaaggcaccaagtcacaagtataatggccacagcagccatgttactaat
gtcagctttactcataatgacagccacttaatttcaactggtggaaaagacatgagtatc
attcagtggagagttgtggagaagttatctttgcctcagaatgagactccagtagatatc
gctataaccaaagcacccatttctaccaatgagaatgtcctacaaccaaatacttccaca
ccacctccctcctcccagcccttcagtgatgctgctgaaaatgaaagaatgagtgattct
tcaacaccccttgagaatgacctggaacaggctgaagaacacagtgaggagcagagtgaa
ggcagcagtgaatacctggctgagcctagttgtgaagagccttccaatgagaccagggaa
gagcagaatgagtcacctattcctgaggaccagcagaattcaccagcttcttaa
DBGET
integrated database retrieval system
